• 대한한의진단학회지
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• 제16권2호
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• pp.1-10
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• 2012

Objectives : Recently, for over ten years, various arterial pulse simulators have been developed for training of pulse palpation technique. In this paper, we summarized development trends of those apparatuses. Materials and methods : To search the cases of development, we mainly used China Knowledge Infrastructure (CNKI), National Discovery for Science Leaders (NDSL), Korean Traditional Knowledge Portal, Patent Search by Baidu (百度專利搜索), and some general search engines. Some domain cases introduced were collected based on personal experience. Results : It was found that there were two types of arterial pulse simulators. The first type uses fluids and pumps, while the second type uses actuators without fluid circulation parts. Conclusion : From year 2000, various arterial pulse simulators have been developed. In general, they could be classified two types. Further effort toward Maixiang (脈象) simulation and validation in field is needed.

• 대한한의진단학회지
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• 제16권1호
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• pp.19-26
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• 2012

Objectives The aim of this study is to develop a cardiovascular simulator that can reproduce blood pressure pulse and blood flow similar to those of the human body. Methods In order to design a system similar to the human cardiovascular system, the required performances were determined by investigating the hemodynamic characteristics of the heart and the arterial system. Main organ to be imitated is heart in simulator. The rest of the system was minimally designed. Also, a blood pressure and blood flow measurement system was developed for measuring the results. Results The developed system showed blood pressure pulse at similar range of the human aorta. The result waveform include primary wave caused by ventricular systole except reflected wave. Conclusions The blood pressure and blow flow patterns were replicated by the simulator. These patterns were similar to those of the human body. The system will play an important role in studying pulse diagnostics.

• 한국정보통신학회:학술대회논문집
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• 한국정보통신학회 2016년도 추계학술대회
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• pp.915-918
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• 2016

의료산업의 급속한 변화와 의료 및 간호 인력의 증가로 인하여 가상 시험 장치에 대한 개발이 요구되고 있으며 심장 모델링할 수 있는 시뮬레이터와 혈관, 혈류에 대한 실습장비에 대한 개발의 중요성이 증가하고 있다. 따라서 본 연구에서는 스텝 모터를 이용하여 심장 펌프를 제작하여 동맥과 정맥 혈압, 혈류 시뮬레이션을 위한 장비를 개발하고 그 기능을 평가하고자 한다. 제안 시스템은 심장 시뮬레이션을 위한 펌프와 동맥, 정맥 혈관의 저항을 모사하기 위한 밸브장치 그리고 정맥계의 특성을 나타내는 저감장치로 구성한다. 심장 시뮬레이터는 롱거펌프(BOXER)를 사용하였으며 동맥과 정맥혈관은 실리콘 튜브를 사용하고 저감장치를 설계 및 제작하였다. 그리고 동맥혈압 측정을 위하여 압력센서를 사용하였다. 또한 제안 시스템의 평가를 위하여 심장 박동수는 분당 60회로 혈압의 범위는 50 ~ 100mmHg로 선정하여 측정 혈압과 사람의 혈압을 비교 평가하였다.

• 한국광학회지
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• 제11권6호
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• pp.452-456
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• 2000

동맥혈의 맥동성분에 의한 파장별 광흡수도를 측정하여 비침습적으로 산소포화도 값을 알수 있는 펄스옥시미터 장치와 신호처리방법을 개발하고 예측 알고리즘을 적용하였다. 본 장치는 광원 및 검출기로 구성된 프로브와 광신호 처리부, LED 구동회로 PC 인터페이스부로 구성되었고 데이터의 수집을 위한 구동소프트웨어 및 데이터 처리 소프트웨어를 개발하였다. 개발된 산소포화도 측정장치의 성능을 평가하는데에는 Bio-Tek 사의 펄스 옥시미터 시뮬레이터를 사용하여 다양한 알고리즘 및 데이터처리 방법들을 비교분석한 결과 맥동파형의 $In(I_p/I_v) 값을 I_{avr}$값으로 보정하는 계산 알고리즘의 방법과 진폭비보다 면적비를 이용한 계산방법이 산소포화도와의 상관관계가 우수한 것으로 나타났다. 정확한 신호 획득을 위해 개발된 맥동의 기저선 보상처리 프로그램을 inv-vivo 테스트의 데이터 처리방법에 적용하여 결과가 향상되는 것을 확인하였고 광원으로 660nm(Red)와 805nm(IR)파장을 이용한 경우보다 660nm(Red)와 940nm(IR) 파장을 이용했을 때 산소포화도와의 상관관계 및 정밀도에서 더 우수한 결과를 얻을 수 있었다.

• Journal of Chest Surgery
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• 제18권2호
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• pp.182-192
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• 1985

[here are so many reports that pulsatile blood flow provides physiologic organ perfusions during cardiopulmonary bypass. So, we compared the recent 30 cases undergoing cardiac surgery by Cobe-Stckert pulsatile roller pump with another 30 cases by Polystan nonpulsatile roller pump. Pulsatile flow was applied during aortic-cross clamping period when synchronized to internal EKG simulator, and perfusion mode was changed to continuous nonpulsatile flow after declamping of aorta. Age, sex, weight, and disease entities were comparable and operative techniques were similar between two groups. 1. There were no differences in average ACC time, ECC time, and Operation time. 2. Postoperative artificial respiration time was 6hrs 30mins in nonpulsatile group and 4hrs 48mins in pulsatile group, and detubation time after ventilator weaning was 2hrs 44mins in nonpulsatile group and 1hrs 43mins in pulsatile group. 3. Average pulse pressure was 8mmHg in nonpulsatile group and 55mmHg in pulsatile group, and a mean arterial pressure was 66.0mmHg in nonpulsatile group and 60.7mmHg in pulsatile group. 4. Mean urine-output during ACC;ECC period was 9.717.3;9.913.2ml/kg/hr in nonpulsatile group and 14.215.0;15.817.5 in pulsatile group [p<0, 05], and thereafter progressive decrease of differences in urine output between two groups until POD 2, and lesser amounts of diuretics was needed in pulsatile group during same postoperative period. Serum BUN/Cr level showed no specific difference and urine concentration power was well preserved in both groups. 5. Plasma proteins and other Enzymes showed no differences between two groups, but serum GOT/GPT level was higher in nonpulsatile group till POD 2. 6. Serum Electrolytes showed no differences between two groups. 7. WBC, RBC, Platelet counts, Hgb and Hct were not different and Coagulogram was well preserved in both groups. 8. Plasma free Hgb level was 7.09mg% in pulsatile group compared with 3.48mg% in pulsatile group on POD 1 but was normalized on POD 2. Gross hemoglobinuria after ECC was noted in 6 cases [20%] of pulsatile group and 4 cases [13%] of nonpulsatile group. 9. In both groups, most patients were included in NYHA class III to IV [28 cases;93% in nonpulsatile group, 22 cases;73% in pulsatile group] preoperatively, and well improved to class I to 11[22 cases; 73% in nonpulsatile group, 30 cases; 100% in pulsatile group] postoperatively. There were 7 operative mortalities in nonpulsatile group only, which were 5 cases of TOF with hepatic failure, 1 case of multiple VSDs with low out-put syndrome, and 1 case of mitral valvular heart disease with cardiomyopathy. We concluded that the new, commercially available Cobe-Stckert pulsatile roller pump device was safe, simple, and reliable.