• 약학회지
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• 제25권2호
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• pp.75-81
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• 1981

Polypenol oxidase activity in the petals of Chysanthemum indicum var. indica Max. (f.sin-dong-a) and the leaves of Artemisia vulgaris var. indica Max was estimated by means of Warburg's manometric method. The browning reaction in owing to the oxidation of chlorogenic acid with polyphenol oxidase.

• Archives of Pharmacal Research
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• 제24권3호
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• pp.194-197
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• 2001

The phytochemical study of the aerial parts of Artemisia japonica ssp. littoricola (Asteraceae) led to the isolation of two acetylenic compounds, (3R)-dehydrofalcarinol (2) and (3R)-dehydrofalcarindiol (6), two sesquiterpenes, $1{\beta}$, $6{\alpha}$-dihydroxy-4(15)-eudesmene (5) and oplodiol (8), and four phenolic compounds, eugenol (1), vanillin (3), 3'-methoxy-4'- hydroxy-trrans-cinnamaldehyde (4) and p-hydroxyacetophenone (7). Their structures were determined by chemical and spectroscopic methods.

• 대한약학회:학술대회논문집
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• 대한약학회 2003년도 Proceedings of the Convention of the Pharmaceutical Society of Korea Vol.2-2
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• pp.153.2-154
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• 2003

Extracts of Artemisia asiatica Nakai (Asteraceae) possess anti-inflammatory and anti-oxidative activities. Eupatilin (5,7-dihydroxy-3,4,6-tri-methoxy-flavone), one of the pharmacologically active ingredients derived from Artemisia asiatica, was shown to induce apoptosis in human promyelocytic leukemia (HL-60) cells (H.-J. Seo and Y.-J. Surh, Mutat. Res., 496, 191-198, 2001). In the present study, we examined the cytostatic effects of eupatilin in H-ras-transformed human breast epithelial (MCF10A-ras) cells. (omitted)

• The Korean Journal of Ecology
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• 제19권4호
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• pp.295-304
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• 1996

KDICical substances from Artemisia scoparia were analyzed by gas chromatography. Seven phenolic compounds and thirty nine terpenoids were identified. Most abundant within each group were cinnamic acid and camphor, respectively. The KDICicals were prepared as aqueous extracts and then used for germination, growth, and chlorophyll content tests. The extracts were inhibitory to germination and seedling growth of the receptor lants. This inhibitory effect was dependent on concentration. When the effect of the aqueous extract on chlorophyll content was assayed, both chlorophylls a and b were shown to be reduced. The reduction in seedling elongation and growth in dry weight paralleled the reduction in chlorophyll concentration. These KDICical substances, including phenolic compounds and terpenoids, from Artemisia scoparia were responsible for the growth inhibition of the selected species.

• 한국식품조리과학회지
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• 제23권4호통권100호
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• pp.413-422
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• 2007

In this study, changes in the volatile compounds of Artemisia capillaris essential oil were investigated under six different storage conditions for 6 months. The essential oil was collected by steam distillation and analyzed by a gas chromatography-mass selective detector (GC-MSD). Seventy-five volatile compounds were identified from the fresh essential oil of Artemisia capillaris. During storage, the total levels of aldehydes, alcohols, and ketones slightly decreased and the level of hydrocarbons greatly decreased; the total level of esters also decreased in the essential oil. Notably, the levels of carvacrol, eugenol, myrcene, 1,8-cineole, caryophyllene, coumarin, ${\alpha}-thujone$, ${\beta}-thujone$, borneol, and ${\gamma}-terpinene$, known as antioxidants and antimicrobial agents, decreased during storage. Finally, aerobic storage conditions caused greater reductions in some compounds even at low temperatures.

• The Korean Journal of Ecology
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• 제21권3호
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• pp.263-268
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• 1998

The composition and concentration of monoterpenes in the leaves of Artemisia japonica were determined. And seasonal variation in monoterpenes of A. japonica were investigated. Samples were taken from five sites at Mt. Muhak. Monoterpenes in the leaves were analyzed using gas chromatography-mass spectrometry. The leaf monoterpene fractions were dominated by R.T. 5.026, ${\alpha}-thujene$, sabinene, ${\beta}-pinene$, cyclohexane (R.T.=12.859) and R.T. 23.149. There were marked seasonal differences in concentration and composition of leaf monoterpenes. There were many kinds of monoterpenes in leaf of spring time, however most of monoterpenes concentration was small. On the other hand, there were not many kinds of monoterpenes in late time, but monoterpene concentrations were increased.

• 생약학회지
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• 제27권2호
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• pp.96-100
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• 1996

The extracts of aerial parts of Artemisia princeps var. orientalis, A. argyi, A. capillaris, A. rubripes and A. laciniata were investigated on the antimutagenic effect againt aflatoxin $B_1$ $(AFB_1)$. The methanolic extracts of 5 Artemisia species reduced the mutagenicity of $AFB_1$. And also 4,5-O-dicaffeoylquinic acid isolated from A. princeps var. orientalis revealed the antimutagenic activity.

• 한국자원식물학회지
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• 제22권3호
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• pp.242-247
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• 2009

Randomly Amplified Polymorphic DNA (RAPD) was performed to define the genetic variation and relationships of Artemisia capillaris. Fifteen populations by the distributions and habitat were collected to conduct RAPD analysis. RAPD markers were observed mainly between 300bp and 1600bp. Total 72 scorable markers from 7 primers were applied to generate the genetic matrix, and 69 bands were polymorphic and only 3 bands were monomorphic. The genetic dissimilarity matrix by Nei's genetic distance (1972) and UPGMA phenogram were produced from the data matrix. Populations of Artemisia capillaris were clustered with high genetic affinities and cluster patterns were correlated with distributional patterns. Two big groups were clustered as southern area group and middle area group. The closest OTUs were GW2 and GG1 in middle area group, and GB1 from southern area group was clustered with OTUs in middle area group. RAPD data was useful to define the genetic variations and relationships of A. capillaris.

• 생약학회지
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• 제49권3호
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• pp.219-224
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• 2018

Artemisia annua L. (Compositae) is an annual herb, which has been traditionally used as an antipyretic and hemostatic agent with the herbal medicine name of Cheong Ho (菁蒿) in Korea and China. In this study, five di-caffeoylquinic acid derivatives and a coumarin were determined from the hot-water extract of aerial parts of A. annua. The structures of isolates were elucidated to be 1,3-di-O-caffeoylqunic acid (1), 3,4-di-O-caffeoylquinic acid (2), 3,5-di-O-caffeoylqiunic acid (3), 1,5-di-O-caffeoylquinic acid (4) and 4,5-di-O-caffeoylquinic acid (5) and scopoletin (6). The presence of 1,5-di-O-caffeoylquinic acid (4) is firstly reported from A. annua in the current study.

• Natural Product Sciences
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• 제9권2호
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• pp.91-92
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• 2003

The present investigation was carried out to evaluate the antinociceptive and sedative - hypnotic effect of a vacuum dried methanol extract of aerial parts of Artemisia pallens. In the tail-flick method with Swiss albino mice the methanol extract at the doses of (1500 mg/kg, 2000 mg/kg, and 2500 mg/kg) showed significant antinociceptive activity. Significant potentiation of Pentobarbitone sodium - induced sleeping time was observed in mice on co-administration of the various doses of the methanol extract of Artemisia pallens.