• Title/Summary/Keyword: aromatic compound

Search Result 295, Processing Time 0.028 seconds

Microbial Degradation of Monohydroxybenzoic Acids

  • Kim, Chi-Kyung;Tim
    • Journal of Microbiology
    • /
    • v.38 no.2
    • /
    • pp.53-61
    • /
    • 2000
  • Hydroxybenzoic acids are the most important intermediates in the degradative pathways of various aromatic compounds. Microorganisms catabolize aromatic compounds by converting them to hydroxylated intermediates and then cleave the benzene nucleus with ring dioxygenases. Hydroxylation of the benzene nucleus of an aromatic compound is an essential step for the initiation and subsequent disintegration of the benzene ring. The incorporation of two hydroxyl groups is essential for the labilization of the benzene nucleus. Monohydroxybenzoic acids such as 2-hydroxybenzoic acid, 3-hydroxybenzoic acid, and 4-hydrosybenzoic acid, opr pyrocattechuic acid that are susceptible for subsequent oxygenative cleavage of the benzene ring. These terminal aromatic intermediates are further degraded to cellular components through ortho-and/or meta-cleavage pathways and finally lead to the formation of constituents of the TCA cycle. Many groups of microorganisms have been isolated as degraders of hydroxybenzoic acids with diverse drgradative routes and specific enzymes involved in their metabolic pahtway. Various microorganisms carry out unusual non-oxidative decarboxylation of aromatic acids and convert them to respective phenols which have been documented. Futher, Pseudomonas and Bacillus spp. are the most ubiquitous microorganisms, being the principal components of microflora of most soil and water enviroments.

  • PDF

A New Antioxidant from the Marine Sponge-derived Fungus Aspergillus versicolor

  • Li, Jian Lin;Lee, Yoon-Mi;Hong, Jong-Ki;Bae, Kyung-Sook;Choi, Jae-Soo;Jung, Jee-H.
    • Natural Product Sciences
    • /
    • v.17 no.1
    • /
    • pp.14-18
    • /
    • 2011
  • A chemical investigation of the marine-derived fungi Aspergillus versicolor led to the isolation of a new aromatic polyketide (1), The structure was elucidated by spectroscopic analysis, and its radical-scavenging activity, reducing power, and inhibitory activity to lipid oxidation were investigated. Those activities of compound 1 were compared with standard antioxidants such as butylated hydroxyanisole (BHA), butylated hydroxytoluene (BHT), tertiarybutylhydroquinone (TBHQ), and ascorbic acid ($V_C$). Compound 1 showed antioxidant activity comparable to that of BHA, and siginificantly higher than that of BHT.

Ethyl Haematommate from Stereocaulon graminosum Schaer.: Isolation and Crystal Structure

  • Ismed, Friardi;Arifa, Nurwahidatul;Zaini, Erizal;Bakhtiar, Amri;Umeda, Daiki;Putra, Okky Dwichandra;Yonemochi, Etsuo
    • Natural Product Sciences
    • /
    • v.24 no.2
    • /
    • pp.115-118
    • /
    • 2018
  • Herein, we reported the phytochemical investigation of whole thallus Sumatran lichen, Stereocaulon graminosum Schaer, and isolated a mono aromatic compound, ethyl haematommate (1). The structure of compound 1 have been established based on spectroscopic data and confirmed by single crystal X-ray structure analysis.

Synthesis and Biological Activity of Aspirin Derivatives

  • Cha, Bae-Cheon;Lee, Seung-Bae
    • Archives of Pharmacal Research
    • /
    • v.23 no.2
    • /
    • pp.116-120
    • /
    • 2000
  • Aspirin has been widely used as analgesic and anti-inflammatory drug. Recently, it was elucidated that aspirin have anti-coaggregatory effect in low dose. This study was carried out to investigate the synthesis of aspirin derivatives from aspirin and aromatic compound of antioxidant and its biological activities. Synthesis of aspirin derivatives was prepared by esterification in the presence of 1, 1-carbonyldiimidazole. Biological activities was examined using effect of anti-coagulant on bleeding time, effect of antioxidant and effect of anti-platelet aggregation. As a result, SJ-101 showed strong antioxidative activity and anti-coagulant activity among four compounds. Anti-platelet aggregation of SJ-101 was examined by collagen, ADP, PAF method. SJ-101 exhibited more stronger activity to aspirin at collagen aggregation reaction. These finding demonstrates that SJ-101 is usefull as care drug of aging and old-disease because of its has antioxidant activity, anti-coagulant activity and anti-platelet activity.

  • PDF

A Short Kinetic Mechanism for Premixed Flames of Aromatic Compound : Benzene (방향족 화합물 화염의 축소 반응 메카니즘 개발 : 벤젠)

  • Lee, Ki Yong
    • Journal of the Korean Society of Combustion
    • /
    • v.20 no.4
    • /
    • pp.49-55
    • /
    • 2015
  • A short kinetic mechanism for premixed benzene/air flames was developed with a reduction method of Simulation Error Minimization Connectivity Method(SEM-CM). It consisted of 38 species and 336 elementary reactions. Flame speeds were calculated and compared with those from full mechanisms and experiments of other researchers. Flame temperature, the heat release rate, the concentration profiles of major species and radicals were also calculated with both mechanism. Those comparisons are in good agreement between the full mechanism and the short mechanism at high pressure condition. In numerical work the running time with the short mechanism was over 12 times faster than one with the full mechanism.

Evaluation of Atmospheric Volatile Organic Compound Characteristics in Specific Areas in Korea Using Long-Term Monitoring Data

  • Jo, Wan-Kuen;Chun, Ho-Hwan;Lee, Sang-Ok
    • Environmental Engineering Research
    • /
    • v.17 no.2
    • /
    • pp.103-110
    • /
    • 2012
  • This study was performed mainly to examine whether a city with a metal industrial presence presents different characteristics in ambient volatile organic compound (VOC) concentrations compared to residential (RES) and commercial/residential combined (CRC) areas of another city by using long-term monitoring data (from January 2006 to February 2009). For most target VOCs, ambient concentrations in the metal-industrialized city were lower than for the RES and CRC areas. Aromatic compounds were the predominant VOC groups for the metal industry city as well as for other land uses. The ambient concentrations of aromatic VOCs were higher in the winter and spring seasons than in the summer and fall seasons, whereas those of chlorinated VOCs did not show any distinctive variations. In addition, higher concentrations were observed during daytime hours. The correlations between the ambient target compounds were statistically significant, except for the correlation between benzene and ozone.

Thermal Cyclization of PHA and its Derivatives(I) - Model compound study - (PHA 및 그 유도체의 열적 고리화 거동 고리화 거동(I) - 모델화합물 연구 -)

  • Kim, Eun-Kyoung;Kim, Myung-Kyoon;Baik, Doo-Hyun
    • Proceedings of the Korean Fiber Society Conference
    • /
    • 2001.10a
    • /
    • pp.361-363
    • /
    • 2001
  • Aromatic pelybenzoxazoles(PBOs) display excellent thermal stability plus good solvent and chemical resistance. Wholly aromatic PBOs, in fact, are soluble only in strong acids(e.g., sulfuric, rmethanesulfonic, triflic, and polyphosphoric acids). However, fully heterocyclized polymers have shown some drawbacks in solubility and processing. This problem of processing is currently being exploited to obtain unusual combinations of physical properties in fibers and films. (omitted)

  • PDF

Genome Analysis of Naphthalene-Degrading Pseudomonas sp. AS1 Harboring the Megaplasmid pAS1

  • Kim, Jisun;Park, Woojun
    • Journal of Microbiology and Biotechnology
    • /
    • v.28 no.2
    • /
    • pp.330-337
    • /
    • 2018
  • Polycyclic aromatic hydrocarbons (PAHs), including naphthalene, are widely distributed in nature. Naphthalene has been regarded as a model PAH compound for investigating the mechanisms of bacterial PAH biodegradation. Pseudomonas sp. AS1 isolated from an arseniccontaminated site is capable of growing on various aromatic compounds such as naphthalene, salicylate, and catechol, but not on gentisate. The genome of strain AS1 consists of a 6,126,864 bp circular chromosome and the 81,841 bp circular plasmid pAS1. Pseudomonas sp. AS1 has multiple dioxygenases and related enzymes involved in the degradation of aromatic compounds, which might contribute to the metabolic versatility of this isolate. The pAS1 plasmid exhibits extremely high similarity in size and sequences to the well-known naphthalene-degrading plasmid pDTG1 in Pseudomonas putida strain NCIB 9816-4. Two gene clusters involved in the naphthalene degradation pathway were identified on pAS1. The expression of several nah genes on the plasmid was upregulated by more than 2-fold when naphthalene was used as a sole carbon source. Strains have been isolated at different times and places with different characteristics, but similar genes involved in the degradation of aromatic compounds have been identified on their plasmids, which suggests that the transmissibility of the plasmids might play an important role in the adaptation of the microorganisms to mineralize the compounds.

Quality and Sensory Characteristics of Transgenic Perilla (Perilla frutescens) Overexpressing Rot 3 gene (형질전환 들깨잎의 품질 및 관능적 특성)

  • Lee, Hyeon-Suk;Kim, Kyung-Tae;Sohn, Jae-Keun;Kim, Kyung-Min
    • Journal of Plant Biotechnology
    • /
    • v.33 no.2
    • /
    • pp.111-115
    • /
    • 2006
  • This study was carried out to establish genetic transformation of Rot 3 gene into perilla plants and to evaluate aromatic compounds, brightness, anthocyanin contents and leaf index in Rot 3 overexpressing transgenic lines. Rot 3 transmitted successfully from T$_1$ to T$_2$ generation showing stable gene expression. It revealed that there was no difference between transgenic and non-transgenic plants in major agronomic characteristics of progeny analysis. There was not much difference in aromatic compounds and leaf brightness did not showed variations between transgenic and non-transgenic, but leaf index was distinguished, respectively.

Analysis of VolatHe Flavour Components in Aromatic Rices using Electronic Nose System (전자코 시스템에 의한 향미의 방향미 성분 분석)

  • 문형인;이재학;이동진
    • KOREAN JOURNAL OF CROP SCIENCE
    • /
    • v.41 no.6
    • /
    • pp.672-677
    • /
    • 1996
  • Volatile flavour components rates from aromatic rices were analyzed by Electronic nose systems. In functional group, polar compounds and aldehyde compounds showed much of volatile flavour components than apolar compounds, sulphur compounds and aminated compounds. The profiles of volatile flavour components rates were markedly differents of sen-sing times, amylose content.

  • PDF