• Title/Summary/Keyword: area study

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Analgesic Effect of Hippophae rhamnoides Extract in Orofacial Pain in Rats (구강안면통증모델에서 산자나무 추출물의 진통효과)

  • Kim, Yun-Kyung;Choi, Ja-Hyeong;Kim, Hee-Jin;Yoon, Hyun-Seo;Hyun, Kyung-Yae;Lee, Min-Kyung
    • Journal of dental hygiene science
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    • v.17 no.6
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    • pp.495-500
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    • 2017
  • Hippophae rhamnoides L. (sea buckthorn) is a shrub wood that belongs to the bamboo tree family, and is rich in vitamin C, D, and E; it is referred to as a vitamin tree. It is mainly grown in the high mountains of Europe and Central Asia, and has been widely used in China and Russia as natural medicine. Recent studies have shown that it is effective in the treatment of cancer, liver diseases, cardiovascular diseases, and gastrointestinal diseases. However, results of studies on its effect on the regulation of pain are insufficient. In this study, we investigated the effect of sea buckthorn on the development and control of pain in two facial areas. The experimental animals included 7- to 8-week-old Sprague-Dawley rats (240~260 g). Formalin (5%), which is known as an inflammation inducer, was injected into the vibrissa pad or temporomandibular joints to induce orofacial acute pain. Rubbing or scraping of the region injected with formalin was regarded as a pain index, and the behavioral response was observed for 45 minutes after the injection. Sea buckthorn extract diluted to 150, 300 mg/kg (in 1 ml of distilled water) was orally administered 30 minutes prior to the acute pain. The facial pain behavior was effectively reduced in the 300 mg/kg group when compared to the control group (vehicle). Likewise, in an experiment in which formalin was injected into the temporomandibular joints, effective pain alleviation was confirmed at the same drug concentration. These results suggest that sea buckthorn extract may be useful in the development of therapeutic agents for acute inflammatory pain in the orofacial area and for controlling temporomandibular joint pain.

The Analysis of Operational Characteristics in Contract - managed Highschool Foodservice in Seoul (서울시 소재 고등학교 위탁급식 운영현황 분석)

  • Yang, Il-Seon;Kim, Hyeon-A;Sin, Seo-Yeong;Jo, Mi-Na;Park, Su-Yeon;Cha, Jin-A;Lee, Bo-Suk
    • Journal of the Korean Dietetic Association
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    • v.8 no.3
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    • pp.280-288
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    • 2002
  • The purpose of this study was to investigate the operational characteristics of the contract-managed highschool foodservice and to analyze the factors to effect the menu price. The data was collected from 249 highschools in Seoul. The results are as follows; Those surveyed highschools were established as 1 national, 74 public, and 174 private institution. Highschools were classified as 176 academic, 66 vocational, and 7 specific purposed institution. Students were organized as 70 boys', 23 girls', and 41 coeducational highschools. Most highschool started contract-managed highschool foodservice from 1999 and the period of foodservice contract was most 3 years and the operation styles in food distribution were 96 classrooms, 105 dining halls and 17 classrooms combined dining halls. The scale of contract foodservice management companies was 63.1% small and medium and 36.9% large enterprises. The surveyed highschools had the average meal price 2,141 won per meal and they had 1,518 pupils on the register. The participating rate to the foodservice was 68.5%. The facilities investment cost of the contract foodservice management company was 179,204,230 won for private institutions and was 138,119,010 won for national&public institutions. The period of the contract was 3.22 years in private institutions, which was significantly higher than national&public institutions which showed 2.85 years. The commissary foodservice schools had higher facilities investment cost than conventional foodservice schools. Classrooms foodservice had higher participating foodservice rate than Dining halls. The investment cost for facilities showed high in order of girls', boys', and coeducational high schools, and the number on the register and the number participating in the foodservice showed high in order of boys', girls', and coeducational high schools. The number on the register showed the highest in academic and vocational schools, specific purposed institutions in sequence, and the number participating in the foodservice showed high in order of academic schools, specific purposed institutions and vocational. However, the participating foodservice rate showed high in specific purposed institution, academic and vocational schools in order, and the meal price, the investment cost for facilities showed high in specific purposed institution, academic and vocational schools in sequence. Regionally, the district south of Han river had the average meal price 2,266.13 won, which showed higher in the eastern part which had 2,033.33 won. The western part had the average investment cost for facilities of 233,331,060 won, and the central district 126,137,140 won. The number on the register showed 1845.68 in the eastern part and 1308.00 in Dong-Jak area, that had clear differences among areas. When the period of the contract went longer, the investment cost for facilities had a tendency to increase. The significant differences were existed among meal price, the investment cost for facilities, the number on the register, the number participating in the foodservice, and the participating foodservice rate. The investment cost for facilities had increased according to the number participating in the foodservice and the participating foodservice rate. And the large enterprises showed higher participating foodservice rate than the small and medium enterprises.

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Effects of Elevated $CO_2$ Concentration and Temperature on the Response of Seed Germination, Phenology and Leaf Morphology of Phytolacca insularis(Endemic species) and Phytolacca americana(Alien species) ($CO_2$농도와 온도증가에 따른 한국특산식물 섬자리공과 귀화식물 미국자리공의 발아, 식물계절 및 잎의 형태학적 반응연구)

  • Kim, Hae-Ran;You, Young-Han
    • Korean Journal of Environment and Ecology
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    • v.24 no.1
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    • pp.62-68
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    • 2010
  • This study was conducted to find out how the germination, phenology and leaf morphology of Phytolacca insularis(endemic species of Korea) and P. americana(alien species) react to the global warming situation. Seed and seedlings of two species were sampled and placed under two separate conditions for the experiment. One of the seed and seedlings was treated in the glass house with control(ambient $CO_2$+ambient temperature, (AC-AT), and the other with control(elevated $CO_2$+ elevated temperature, EC-ET), over the period of one year, 2008-2009. The germination rate of two species was fast, and the time of their germination started early, when they were treated at EC-ET than at AC-AT. Furthermore, the germination rate of Phytolacca insularis(endemic species of Korea) was found to be comparatively lower than that of P. americana(alien species). The former showed only vegetative growth whereas the latter showed both vegetative growth and reproductive growth in one year period. The more $CO_2$ degree and temperature increased, phenological responses of two species, including leaf growth, the formation of flower stems, flowering, and fruit maturing, became much faster, and the time of their leaf-yellowing was delayed. The lamina length of P. insularis was not significantly affected by elevated $CO_2$ and temperature. The lamina length of P. americana, on the other hand, became longer at EC-ET than at AC-AT, but the leaf width of both species increased at EC-ET. As for the number of leaves, both species showed no difference. Finally, the ratio of the leaf area of P. insularis was high at AC-AT, but P. americana was high at EC-ET. These results indicate that P. americana, aliens species, reacts more sensitively to global warming than P. insularis, endemic species, does.

Effect of the Preparation Method on the Activity of CeO2-promoted Co3O4 Catalysts for N2O Decomposition (촉매 제조방법에 따른 Co-CeO2 촉매의 N2O 분해 특성 연구)

  • Kim, Hye Jeong;Kim, Min-Jae;Lee, Seung-Jae;Ryu, In-Soo;Yi, Kwang Bok;Jeon, Sang Goo
    • Clean Technology
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    • v.24 no.3
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    • pp.198-205
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    • 2018
  • This study investigated the influence of catalyst preparation on the activity of $Co-CeO_2$ catalyst for $N_2O$ decomposition. $Co-CeO_2$ catalysts were synthesized by co-precipitation and incipient wetness impregnation. In order to estimate the performance of the as prepared catalysts, direct catalytic $N_2O$ decomposition test was carried out under $250{\sim}375^{\circ}C$. As a result, the catalyst prepared by co-precipitation (CoCe-CP) showed an enhanced performance on $N_2O$ decomposition reaction even in the presence of $O_2$ and/or $H_2O$, whereas the impregnation catalyst (CoCe-IM) did not. In order to investigate the difference in catalytic activity, characterization such as XRD, BET, TEM, $H_2-TPR$, $O_2-TPD$, and XPS was conducted. It is confirmed that the particle size and specific surface area were changed depending on the catalyst preparation method and the synthesis process influenced the physical properties of the catalysts. In addition, the improvement in the activity of the catalyst prepared by co-precipitation is due to the enhanced reduction from $Co^{3+}$ to $Co^{2+}$ and the improved oxygen desorption rate. However, it has been confirmed that the surface electron state and binding energy, which are related to $N_2O$ decomposition, do not change depending on the preparation method.

A Comparison of Herbage Use, Grazing and Social Behaviour by Livestock Grazing under Grassland Types (초지류형별(草地類型別) 방목축(放牧畜)에 의한 목초이용(牧草利用)과 방목(放牧) 및 사회습성(社會習性) 비교(比較))

  • Lee, In Duk;Myoung, Jeon;Seong, Woo Suk;Raim, Dong Chan
    • Korean Journal of Agricultural Science
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    • v.13 no.2
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    • pp.219-226
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    • 1986
  • A study was conducted to provide direct comparisons of the effect of variations in herbage use, grazing and social behaviour upon the flat, slope and forest grassland with a total 30 Korean Native Cattle and 5 Korean Native Goats under 4-year old grassland established by intensive sowing method in Daecheon. The results obtained are summarized as follows; 1. Relative intake index, dry matter intake per animal and dry matter digestibility by Korean Native Goats in flat, slope and forest grassland were 35.2%-462g-63.7%, 35.0%-459g-63.0% and 29.8%-391g-62.1%, respectively. 2. Grazing time by Korean Native Cattle was not different among the grassland types, but ruminating time was increased in slope grassland, whereas in forest grassland was decreased. Resting time was increased in forest grassland, whereas in slope grassland was decreased. Walking time was increased in flat grassland, but loafing time was increased in forest grassland. The number of rumination, chews per bolus and defecation number were decreased in forest grassland. The number of drinks, total drinking water and walking distance were increased in slope grassland. 3. Animal distance, occupied area per animal and sub group formation by Korean Native Cattle in flat, slope and forest grassland were $3.4m-11.9m^2-3.6head$, $3.56m-11.0m^2-3.7head$ and $3.70m-14.6m^2-3.4head$, respectively. The order of grazing movement was similar to the pear-shaped grazing formation, but the relations of dominance between first grazer and last grazer upon different grassland types was not clear.

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Factors Affecting the Satisfaction for Medical Service and Reuse Intention of Patients at Dental Clinic in Gyeongnam Province (경남 일부지역 치과의원 내원 환자들의 치과 의료서비스 질 만족도와 재이용 의사에 미치는 영향 요인)

  • Seong, Mi-Gyung;Kim, Jae-Hwa;Jang, Kyeung-Ae
    • Journal of dental hygiene science
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    • v.15 no.2
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    • pp.106-112
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    • 2015
  • This study was conducted to provide with baseline data with the purpose of increasing the values of medical services. Self-administered questionnaire survey was conducted on 236 patients at a dental clinic follow-up visit in dentist clinic Gyeongnam area from June 2013 to August 2013. All statistical analyses were performed using SPSS. The motivation visiting the dental clinic is that the first one is introduction from the family and friends, the second is accessibility, the third is conspicuity and the last one is awareness of the dentist. The main variables in the process of treatment are service system, kindness, satisfaction of service, efficient of re-call system. The relief of discomfort at revisit show the highest score in the process of implant treatment and intention of revisit hereafter do in the prostheses process. In the correlation between main variables, service system and relief of discomfort at revisit (r=0.440, p<0.001), kindness and satisfaction of medical service (r=0.675, p<0.001), revisit hereafter and satisfaction of service (r=0.387, p<0.001) and efficiency of re-call system and revisit showed the highest correlation. The influence on satisfaction of dental service show meaningful level in kindness (p<0.001) and efficiency of re-call system (p<0.05). The intention of revisit is affected meaningfully by relief of uncomfort (p<0.05), service system (p<0.05), kindness (p<0.01) and efficiency of re-call system (p<0.01). In summary, the personal network of patients is most important variable at intention for revisit of dental clinic. As satisfaction of kindness and efficiency of re-call system is higher, satisfaction of medical service and intention for revisit are shown higher. Therefore further research for improvement of satisfaction for medical service and of intention of revisit at the dental clinic should be carried out.

Protein Patterns of Ovary and Hemolvmph in Gerris paludum

  • 황명실;최원철
    • The Korean Journal of Zoology
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    • v.32 no.4
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    • pp.337-350
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    • 1989
  • In this study, we compared patterns of hemolvmph with ovarian proteins during the yolk formation of Gewis paludum by using SDS/polyacrylamide gel electrophoresis and he dimen-tlonal electrophoresis. In addition, we examined patterns of glycoprotein which were composed of yolk substances. The results were as follows: The protein patterns in ovary of the 5th instar without eggs were similar to those of adult after ovulation. Protein amounts of the ovaw without developing eggs were less than those of the ovaw containing oocvtes or matured eggs at the molecular weights range from 66, 000 to 110.000 daltons. No glvcoproteins were observed in ovaw without eggs. But the glvcoproteins were gradually increased according to development of eggs in the 5th instar. After the ovulated ovaw of adult, no glvcoprotein bands urere occurred as the bands of the ovary without eggs in the 5th instar. Also, amounts of hemolvmph protein between 66, 000 and 110, 000 in molecular weight were increased during yolk formation of the 5th instal. The results suggest that ovarian protein substances may originate from hemolpnph. In the 5th instar, the amounts of glycoprotein of developing eggs was gradually increased in the hemolymph. The band of M.W. 29, 500 was occurred in the hemolpnph of the 5th instar and adult without eggs. This protein mal be precursor of glvcoprotein in the high molecular weight area in the ovary of more developed eggs. The number of spots and the amounts of protein in ovary without eggs were less than those of ovary containing eggs by two dimensional elec-trophoresis. The protein bands between 45, 000 and 110, 000 almost appeared in acidic field of he dimensional gel. Especially, the band, M.W. 109, 000, uras separated 3 spots, a1, a2, and as. The band, M.W. 102, 000, has spots which designated b1, b2, b3, and b4. Besides, proteins below M.W. 24, 000 were occurred less spots in the basic field than those of acidic field. The mechanism of intracellular organs (= cell organells) uras related to the yolk protein synthesis of oocyte in the process of yolk protein formation of derris pcfudum.

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Establishment of a Single Dose Radiation Model of Oral Mucositis in Mice (일회 방사선조사를 이용한 마우스 구강점막염 모델의 확립)

  • Ryu, Seung-Hee;Moon, Soo-Young;Choi, Eun-Kyung;Kim, Jong-Hoon;Ahn, Seung-Do;Song, Si-Yeol;Park, Jin-Hong;Noh, Young-Ju;Lee, Sang-Wook
    • Radiation Oncology Journal
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    • v.26 no.4
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    • pp.257-262
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    • 2008
  • Purpose: Oral mucositis induced by radiotherapy to the head and neck area, is a common acute complication and is considered as the most severe symptom for cancer patients in the early stages of treatment. This study was proposed to establish the oral mucositis mouse model induced by a single dose of radiation for the facility of testing therapeutic candidates which can be used for the oral mucositis treatments. Materials and Methods: Fifty-five BALB/c mice were divided into four groups: control, 16 Gy, 18 Gy, and 20 Gy. Oral mucositis was induced by a single dose of radiation to the head and neck using 6 MV x-Ray from linear accelerator. After irradiation, body weight and physical abnormalities were checked daily. Tongue tissues from all groups were taken on days 1, 2, 3, 5, 7, 9, and 14, respectively and H&E staining was conducted to examine morphological changes. Results: Body weight dramatically decreased after day 5 in all irradiated mice. In the 16 Gy treatment group, body weight was recovered on day 14. The histology data showed that the thickness of the epithelial cell layer was decreased by the accumulated time after radiation treatment, up to day 9. Severe ulceration was revealed on day 9. Conclusion: A single dose of 16 Gy is sufficient dose to induce oral mucositis in Balb/C mice. Significant changes were observed in the Balb/C mice on days 7 and 9 after radiation. It is suggested that this mouse model might be a useful standard tool for studying oral mucositis induced by radiation.

Toothpick-Aided Detection of Sclerotinia homoeocarpa in the Turfgrass Leaf Canopy, Thatch, and Soil in Relation to Dollar Spot Infection Centers (이쑤시개를 이용한 잔디층, 대취층, 및 토양층에서 동전마름병 전염원의 검출)

  • Lee, Jung Han;Min, Gyu Young;Shim, Gyu Yul;Kim, Dong Soo;Sang, Hyunkyu;Jung, Geunhwa;Kwak, Youn-Sig
    • Weed & Turfgrass Science
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    • v.4 no.4
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    • pp.376-382
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    • 2015
  • Dollar spot, caused by Sclerotinia homoeocarpa, is the major disease in cool-season turfgrasses. Understanding the distribution of this pathogen in soil and thatch is important to developing disease control strategies. In this study, toothpicks were used to detect S. homoeocarpa in the turfgrass canopy, thatch, and soil at different distances from dollar spot infection centers. The effect of penetrant and contact fungicide applications with different water volumes on distribution of S. homoeocarpa was also investigated. S. homoeocarpa was detected in 100% of samples taken from the leaf canopy, 83.3% in thatch area, and 0% in the soil from within the infection center. S. homoeocarpa was isolated in 100% of samples taken from the edge of the infection center, but was only detected in 13% of the samples taken at 1.5 cm away from the infection center edge. S. homoeocarpa was isolated at a higher frequency in the propiconazole treated plots than those treated with chlorothalonil and was not detected in leaf canopy samples when either fungicides was applied with 6.78 L of water. In conclusion, the toothpick-aided detection technique has improved our understanding of S. homoeocarpa epidemiology and could be used as a diagnostic tool to detect for fungicide resistance on golf courses.

Evaluation of Tissue Inhomogeneity for Gamma-knife Radiosurgery Using Film Dosimetry (감마 나이프 방사선 수술시 필름 선량 측정에 의한 조직 불균일성에 대한 연구)

  • Cho, Heung-Lae;Shon, Seung-Chang;Shu, Hyun-Suk
    • Radiation Oncology Journal
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    • v.16 no.3
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    • pp.325-335
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    • 1998
  • Purpose : Since the mid cranial fossa is composed of various thickness of bone, the tissue inhomogeneity caused by bone would produce dose attenuation in cobalt-60 gamma knife irradiation. The correction factor for bone attenuation of cobalt-60 which is used for gamma knife source is -3.5$\%$. More importantly, nearly all the radiosurgery treatment planning systems assume a treatment volume of unit density: any perturbation due to tissue inhomogeneity is neglected, This study was performed to confirm the bone attenuation in mid cranial fossa using gamma knife. Materials and Methods : Computed tomography was performed after Leksell stereotactic frame had been liked to the Alderson Rando Phantom (human phantom) skull area. Kodak X-omat V film was inserted into two sites of pituitary adenoma point and acoustic neurinoma point, and irradiated by gamma knife with 14mm and 18mm collimator. An automatic scanning densitometer with a 1mm aperture is used to measure the dose profile along the x and y axis. Results : Isodose curve constriction in mid cranial fossa is observed with various ranges. Pituitary tumor point is greater than acoustic neurinoma point (0.2-3.0 mm vs 0.1-1.3 mm) and generally 14 mm collimator is greater than 18mm collimator (0.4-3.0 mm vs. 0.2-2.2 mm) Even though the isodose constriction is found, constriction of 50$\%$ isodose curve which is used for treatment reference line does not exceed 1 mm. This range is too small to influence the treatment planning and treatment results. Conclusion : Radiosurgery planning system of gamma knife does not show significant error to be corrected without consideration of bone attenuation.

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