• Title/Summary/Keyword: arches

Search Result 349, Processing Time 0.023 seconds

Mecoprop-p interrupts the development of zebrafish via apoptosis and vascular damage

  • Park, Junho;An, Garam;Park, Hahyun;Hong, Taeyeon;Song, Gwonhwa;Lim, Whasun
    • Journal of Animal Reproduction and Biotechnology
    • /
    • v.37 no.3
    • /
    • pp.162-168
    • /
    • 2022
  • Mecoprop-p, a chlorophenoxy herbicide, has been widely used since the 1980s. Due to its high water solubility, it could be detected in the aquatic environment, as it has already been detected in the surface water or groundwater in several countries. The toxicity of other chlorophenoxy herbicides has been reported; however, there are few studies on the toxicity of mecoprop-p, one of the chlorophenoxy herbicides, on aquatic organisms. Here, we investigated the toxic effects of mecoprop-p using zebrafish. After mecoprop-p exposure, we observed that the zebrafish larvae eyes did not form normally, heart edema was generated, and the body length was shortened. The number of cells undergoing apoptosis also increased in the anterior part including head, heart, and yolk sac of the mecoprop-p-treated zebrafish compared to the untreated controls. Moreover, cardiovascular structures, including the heart and aortic arches, were also malformed after exposure to mecoprop-p. Therefore, our results suggest that mecoprop-p could cause abnormal development in zebrafish larvae and there is also a high possibility that mecoprop-p would be toxic to other aquatic organisms.

Investigation on the masonry vault by experimental and numerical approaches

  • Guner, Yunus;Ozturk, Duygu;Ercan, Emre;Nuhoglu, Ayhan
    • Earthquakes and Structures
    • /
    • v.23 no.1
    • /
    • pp.13-21
    • /
    • 2022
  • Masonry constructions exhibit uncertain behaviors under dynamic effects such as seismic action. Complex issues arise in the idealization of structural systems of buildings having different material types and mechanical properties. In this study, the structural behavior of a vaulted masonry building constructed using full clay brick and lime-based mortar and sitting on consecutive arches was investigated by experimental and numerical approaches. The dimensions of the structure built in the laboratory were 391 × 196 cm, and its height was 234 cm. An incremental repetitive loading was applied to the prototype construction model. Along the gradually increasing loading pattern, the load-displacement curves of the masonry structure were obtained with the assistance of eight linear displacement transducers. In addition, crack formation areas, and relevant causes of its formation were determined. The experimental model was idealized using the finite element method, and numerical analyses were performed for the area considered as linear being under similar loading effect. From the linear analyses, the displacement values and stress distribution of the numerical model were obtained. In addition, the effects of tie members, frequently being used in the supports of curved load-bearing elements, on the structural behavior were examined. Consequently, the experimental and numerical analysis results were comparatively evaluated.

Behaviour of soil-steel composite bridge with various cover depths under seismic excitation

  • Maleska, Tomasz;Beben, Damian
    • Steel and Composite Structures
    • /
    • v.42 no.6
    • /
    • pp.747-764
    • /
    • 2022
  • The design codes and calculation methods related to soil-steel composite bridges and culverts only specify the minimum soil cover depth. This value is connected with the bridge span and shell height. In the case of static and dynamic loads (like passing vehicles), such approach seems to be quite reasonable. However, it is important to know how the soil cover depth affects the behaviour of soil-steel composite bridges under seismic excitation. This paper presents the results of a numerical study of soil-steel bridges with different soil cover depths (1.00, 2.00, 2.40, 3.00, 4.00, 5.00, 6.00 and 7.00 m) under seismic excitation. In addition, the same soil cover depths with different boundary conditions of the soil-steel bridge were analysed. The analysed bridge has two closed pipe-arches in its cross section. The load-carrying structure was constructed as two shells assembled from corrugated steel plate sheets, designed with a depth of 0.05 m, pitch of 0.15 m, and plate thickness of 0.003 m. The shell span is 4.40 m, and the shell height is 2.80 m. Numerical analysis was conducted using the DIANA programme based on the finite element method. A nonlinear model with El Centro records and the time history method was used to analyse the problem.

Evaluation of the relation between the pulp stones and direct restorations using cone beam computed tomography in a Turkish subpopulation

  • Guzide Pelin Sezgin ;Sema Sonmez Kaplan;Tuna Kaplan
    • Restorative Dentistry and Endodontics
    • /
    • v.46 no.3
    • /
    • pp.34.1-34.9
    • /
    • 2021
  • Objectives: This study aimed to assess the presence of pulp stones through an examination of cone beam computed tomography images and correlate their prevalence with age, sex, dental arch and side, tooth type, and restoration type and depth. Materials and Methods: Cone beam computed tomography images obtained from 673 patients and archival data on 11,494 teeth were evaluated. The associations of pulp stones with age, sex, dental arch and side, tooth type, and restoration type and depth were noted. All the measurements were subjected to a χ2 test and one sample χ2 test (p < 0.05). Results: In the study group, 163 (24.2%) patients and 379 (3.3%) teeth had at least one pulp stone. The pulp stone frequency in those aged 30-39 years was significantly greater than in those aged 18-29 and ≥ 60 years, and the frequency was higher in females than in males (p < 0.05). The highest prevalence of pulp stones was found in maxillary dental arches and molar teeth (p < 0.05). Pulp stones were significantly more common in medium-depth restorations (p < 0.05). Conclusions: Maxillary molar teeth, medium-depth restorations, individuals aged 30-39 years and females had a greater percentage of pulp stones.

Free Vibrations of Elastica Shaped Arches with Linear Taper (선형 변단면 정확탄성곡선형 아치의 자유진동)

  • Lee, Byoung Koo;Lee, Tae Eun;Kim, Gwon Sik
    • KSCE Journal of Civil and Environmental Engineering Research
    • /
    • v.29 no.6A
    • /
    • pp.617-624
    • /
    • 2009
  • This study deals with the free vibrations of the elastica shaped arch with linear taper. The shape of elastica is obtained from the Bernoulli-Euler beam theory. Differential equations governing free vibrations of such arch are derived and numerically solved to determine natural frequencies, in which three kinds of taper type and two kinds of end constraint, respectively, are considered. For validating the theories presented herein, the frequency parameters obtained in this study are compared to those of SAP 2000. As results of the numerical analyses, effects of end constraint, taper type, slenderness ratio and section ratio on the lowest four non-dimensional frequency parameters are extensively investigated.

Comparative Analysis of T4SS Molecular Architectures

  • Mishghan Zehra;Jiwon Heo;Jeong Min Chung;Clarissa L Durie
    • Journal of Microbiology and Biotechnology
    • /
    • v.33 no.12
    • /
    • pp.1543-1551
    • /
    • 2023
  • The recently published high-resolution R388 T4SS structure provides exciting new details about the complete complex of T4SS, including the components making up the stalk and arches, numerous symmetry mismatches between regions of the complex, and an intriguing interpretation of the closed stalk and radial symmetry of the inner membrane complex, which is related to pilus biogenesis assembly. However, there are a few unidentified densities in the electron microscopy map and portions of the identified component sequences for which the structure is not yet known. It is also unclear how well this minimized DNA-transporting T4SS predicts the structure of other T4SSs, such as expanded systems and those that transport proteins rather than DNA. In this review, we evaluate what can be inferred from the recent high-resolution structure of the R388 T4SS with respect to the Cag and Dot/Icm systems. These systems were selected because, given what is currently known about these systems, we expect them to present most structural differences compared to the R388 T4SS structure. Furthermore, we discuss bacterial physiology and diversity, the T4SS structures and their variations between different bacterial species. These insights may prove beneficial for researchers who elucidate the structure and functions of T4SS in different bacterial species.

TREATMENT OF TRANSVERSE DEFICIENCY WITH SURGICALLY ASSISTED RAPID PALATAL EXPANSION IN AN OPEN BITE PATIENT SHOWING PSEUDOMACROGLOSSIA (상대적 거대설을 보이는 전치부 개방교합 환자의 외과적 급속 구개확장술을 통한 횡적 부조화의 치험례)

  • Kim, Yoon-Ji;Lee, Kyu-Hong;Park, Jun-Woo;Rhee, Gun-Joo;Cho, Hyung-Jun;Park, Yang-Ho
    • Journal of the Korean Association of Oral and Maxillofacial Surgeons
    • /
    • v.34 no.3
    • /
    • pp.376-382
    • /
    • 2008
  • Anterior open bite is a condition in which maxillary and mandibular incisors do not occlude at central occlusion. It is a vertical discrepancy of the jaws and dental arches that has many etiologic factors making it difficult in diagnosis, treatment and prediction of prognosis. One of the causes of open bite is abnormal size and shape of the tongue. Macroglossia, a condition in which tongue is oversized, is caused by several factors which are not clearly identifiable, and it may be a major factor of anterior and posterior open bite. Macroglossia is subdivided into true, functional and pseudomacroglossia depending on its relative size in the oral cavity. In this case report, a patient was diagnosed as skeletal Class II with pseudomacroglossia, and was treated with SARPE in order to expand the narrowed maxillary arch and Quad helix for the mandibular arch. As a result the transverse deficiency was treated. In the adult patients where no skeletal growth is expected, SARPE has shown to be effective in treating maxillomandibular transverse discrepancies in which macroglossia was accompanied as in this case.

Biomechanical Analysis for the Development of Windlass Mechanism for Trail-walking Shoe (윈들라스 메커니즘을 적용한 트레일 워킹화 개발을 위한 생체역학적 분석)

  • Park, Jong-Jin;Park, Seung-Bum
    • Korean Journal of Applied Biomechanics
    • /
    • v.25 no.4
    • /
    • pp.489-498
    • /
    • 2015
  • Objective : The purpose of this study was to analyze the effects of the windlass mechanism in trail-walking shoe prototypes that can effectively support arches. A study of these effects should help with the development of a first-rate trail-walking shoe development guide for the distribution of quality information to consumers. Methods : The subjects were ten adult males who volunteered to participate in the study. Shoes from three companies, which will be referred to as Company S (Type A), Company M (Type B), and Company P (Type C), were selected for the experiment. The subjects wore these shoes and walked at a speed of 4.2 km/h, and as they tested each shoe, the contact area, maximum pressure average, and surface force were all measured. Results : Shoe Type A showed a contact area of $148.78{\pm}4.31cm^2$, Type B showed an area of $145.74{\pm}4.1cm^2$, and Type C showed an area of $143.37{\pm}4.57cm^2$ (p<.01). Shoe Type A demonstrated a maximum average pressure of $80.80{\pm}9.92kPa$, Type B an average of $85.72{\pm}11.01kPa$, and Type C an average of $89.12{\pm}10.88bkPa$ (p<.05). Shoe Type A showed a ground reaction force of $1.13{\pm}0.06%BW$, Type B a force of $1.16{\pm}0.04%BW$, and Type C a force of $1.16{\pm}0.03%BW$ (p<.05). Conclusion : The Type A trail-walking shoe, which was designed with a wide arch from the center of the forefoot to the front of the rearfoot showed excellent performance, however, more development and analysis of the windlass mechanism for a variety of arch structures is still necessary.

Anatomic Variations of Cervical and High Thoracic Ligamentum Flavum

  • Yoon, Sang Pil;Kim, Hyun Jung;Choi, Yun Suk
    • The Korean Journal of Pain
    • /
    • v.27 no.4
    • /
    • pp.321-325
    • /
    • 2014
  • Background: Epidural blocks are widely used for the management of acute and chronic pain. The technique of loss of resistance is frequently adopted to determine the epidural space. A discontinuity of the ligamentum flavum may increase the risk of failure to identify the epidural space. The purpose of this study was to investigate the anatomic variations of the cervical and high thoracic ligamentum flavum in embalmed cadavers. Methods: Vertebral column specimens of 15 human cadavers were obtained. After vertebral arches were detached from pedicles, the dural sac and epidural connective tissue were removed. The ligamentum flavum from C3 to T6 was directly examined anteriorly. Results: The incidence of midline gaps in the ligamentum flavum was 87%-100% between C3 and T2. The incidence decreased below this level and was the lowest at T4-T5 (8%). Among the levels with a gap, the location of a gap in the caudal third of the ligamentum flavum was more frequent than in the middle or cephalic portion of the ligamentum flavum. Conclusions: The cervical and high thoracic ligamentum flavum frequently has midline intervals with various features, especially in the caudal portion of the intervertebral space. Therefore, the ligamentum flavum is not always reliable as a perceptible barrier to identify the epidural space at these vertebral levels. Additionally, it may be more useful to insert the needle into the cephalic portion of the intervertebral space than in the caudal portion.

Spacing and crowding of the primary dentition in Korean children - relationship to tooth sizes and dental arch dimension (한국인 아동의 유치열기의 특성 - 치아 치열궁의 관계)

  • Im, Dong-Hyuk;Kim, Tae-Woo;Nahm, Dong-Seok;Chang, Young-Il
    • The korean journal of orthodontics
    • /
    • v.36 no.1 s.114
    • /
    • pp.84-90
    • /
    • 2006
  • The aims of this study were to investigate the prevalence of spaced, closed, and crowded primary dentitions by sex and arch in Korean children from Kanghwa, and to determine the frequency of the primate and developmental spaces. The differences in the mesiodistal crown diameters and the arch dimensions between the spaced, closed, and crowded primary dentitions were also evaluated. Dental casts of 102 preschool children (57 males and 45 females, aged $4{\sim}5$ years) were studied. The prevalence of spacing in the primary dentition was 63.2% In males and 57.8% in females. The frequency of spacing was greater in males than in females, and greater in the maxillary arch than in the mandibular arch. The crowns were significantly larger and the arches significantly narrower in closed and crowded dentitions than in those with spacing (p<0.05). The results showed that the prevalence of spacing was lower than that found in previous studies and the presence of spacing in the anterior region was related to the mesiodistal crown diameter and the intercanine width.