• Journal of Chest Surgery
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• 제24권10호
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• pp.1011-1018
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• 1991

From September, 1985 to March, 1991, 33 patients under went thoracotomy for treatment of pulmonary aspergilloma with Pulmonary tuberculosis on the department of Thoracic and Cardiovascular Surgery, National Kongju Hospital. 1. There were 25 male and 8 female patients ranging from 19 to 57 years old [mean age, 36.2 years]. 2. Hemoptysis was the most common symptom [recurrent minor hemoptysis: 24cases, severe hemoptysis [200cc /day]: 4 cases, massive hemoptysis [600/day]: 4 cases]. 3. In the chest X-ray films, intracavitary fungus balls [air meniscus sign] were noted in 20 cases [61%] and upper lobe involvements were 29 cases [88%]. 4. All cases had a history of treatment with antituberculosis drugs under diagnosis of pulmonary tuberculosis for an average of 10 years and 2 months. 5. The most common indication for operation was hemoptysis [32 cases] - hemoptysis with total destroyed lung or lobe: 12cases, hemoptysis with open AFB [t-] cavity: 6cases, recurrent or massive hemoptysis: 14 cases. 6. The operative procedures was as follows - - - lobectomy . 16 cases, pneumonectomy: 8 cases, bilobectomy, segmentectomy, cavernoplasty and lobectomy with segmentectomy: each 2 cases, lobectomy with cavernoplasty: 1 case. 7. 6 complications appeared postoperatively which included empyema with BPF [2 cases], empyema [2 cases] and wound infection [2 cases]. In conclusion, surgical resection is the treatment of choice in the management of pulmonary aspergilloma associated pulmonary tuberculosis.

• 미생물학회지
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• 제27권2호
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• pp.155-161
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• 1989

Lactobacillus sporogenes를 NTG로 처리하여 rifampicin에 내성인 돌연변이 균주를 얻었으며, 이중 58 종이 rifampicin에 현저한 내성을 보였다. 9종의 mutants를 선발하여 그 생화학적 특성을 검토한 결과, 포자형성능, 산생성능, E. coli 생육억제능 면엣 parent와 유사한 특성을 나타내었다. In vitro 시험을 통해ㅐ, 내성균주들에 의해 rifampicin이 불활성화 되지 않음이 밝혀졌다. 따라서 이들 mutants를 유산균 제제원으로 사용할 수 있으며, 그 제제는 rifampicin과 병용투여시, 효과적인 정장제로 사용될 수 있을 것으로 사료된다.

• Tuberculosis and Respiratory Diseases
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• 제43권5호
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• pp.818-823
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• 1996

The tumorous type of endobronchial tuberculosis was reponed to be 5 to 10% in the bronchoscopic examination. It was protruding mass that tuberculosis mediastinal lymph nooe ruprured into the bronchial lumen. Generally histologic examination has been performed for purpose of differentiation, because the tuberculosis type of endobronchial tuberculosis simulate lung cancer in bronchoscopic finding. A case considering operation similar to bronchial adenoma in the bronchoscopic finding was confirmed to endobronchial tuberculosis by JX5itive AFB and disapperance of mass after antituberculosis medication. Case history was presented and reviewed.

• Archives of Pharmacal Research
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• 제28권7호
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• pp.854-858
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• 2005

A Lactobacillus isolate was collected from the feces of a healthy Korean individual and named as Lactobacillus ruminus SPM0211. It was further characterized by subjecting it to an antibiotic resistance test and genetic analysis. In the antibiotic resistance test, all tested Lactobacillus spp. were classified as 'high resistance' for multiple antibiotics, such as isoniazid, ethambutol, cycloserine, and vancomycin. L. ruminus SPM0211 was classified as 'high resistance' for streptomycin also, while the other tested Lactobacillus spp. were classified as low resistance. This suggests that the antimicrobial spectra may be a good indicator in the discrimination of this strain among the tested Lactobacillus spp. In a polymerase chain reaction-random amplified polymorphic DNA (PCR-RAPD) analysis using the Microbial Uniprimer kit, L. ruminus SPM0211, and L. suebicus were clustered as a group with a 74.3% similarity level, suggesting that these two species are genetically related. Thus, our data suggest that the PCR-RADP method using the Microbial Uniprimer kit may be valuable in discriminating L. ruminus SPM0211 from other Lactobacillus spp.

• Pediatric Infection and Vaccine
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• 제9권1호
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• pp.117-121
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• 2002

어린 영유아에서 결핵성 육아종 및 결핵성 수막염, 속립성 결핵 등의 중증 결핵은 치료 시작시 임상상태와 밀접한 연관이 있으며 경과가 진행될수록 예후가 좋지 못하다. 본 증례에서는 결핵성 육아종과 함께 결핵성 수막염 및 속립성 결핵이 동반된 영아에서 12개월 동안 항결핵 요법을 시행한 후 특별한 임상적, 이학적, 신경학적 이상 소견 없는 완치를 경험하였기에 문헌 고찰과 함께 보고하는 바이다.

• Journal of Preventive Medicine and Public Health
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• 제7권1호
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• pp.185-190
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• 1974

우리나라 결핵관리(結核管理)에 있어서 보건소(保健所) 등록대상자(登錄對象者)를 경증환자(輕症患者)까지 확대(擴大)하여 치료가능성(治療可能性) 환자(患者)를 취급(取扱)함이 요망(要望)되며 치료방식(治療方式)에 있어서도 맹목적(盲目的)으로 일차약(一次藥)만을 사용(使用)할 것이 아니라 내성균소지자(耐性菌所持者)에 대(對)해서는 이차약(二次藥) 투약(投藥)도 시도(試圖)하여아 하며 화학요법(化學療法) 일방(一方)으로만 하지 말고 외과적응증(外科適應症)에 대(對)해서도 적절(適切)한 외과적수술(外科的手術)을 시행(施行) 할것이 요망(要望)된다. 퇴녹자(退錄者)의 50%가 활동성(活動性)임이 추측(推測)됨으로 이들에 대한 적절(適切)한 대책(對策)이 시급(時急)하다. 기발견(旣發見)된 결핵환자(結核患者)가 전체적(全體的)으로는 50%정도(程度)이나 중등증이상(中等症以上)에만 국한(局限)시킨다면 80%이상(以上)에 달(達)함으로 무계획적(無計劃的)인 검진사업(檢診事業)에 과중(過重)한 비용(費用)을 허비(虛費)하지 말고 치료사업(治療事業)이나 예방사업(豫防事業)에 경비(經費)를 더 많이 투입(投入)함이 요망(要望)된다.

• 셀메드
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• 제3권3호
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• pp.19.1-19.32
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• 2013

Piper sarmentosum is a creeping herb belongs to the family of Piperaceae. It is locally known to the Malays as 'Pokok kadok' and can be found in different regions of South-East Asia including Malaysia. Ethnopharmacologically, various parts of the plant (e.g. leave, fruit and root) are widely used in Asian countries for centuries to treat different types of diseases and ailments such as hypertension, diabetes, joint aches, muscle pain, coughs, influenza, toothaches and rheumatism. Scientific findings also demonstrated different pharmacological actions of various parts of P. sarmentosum such as adulticidal, antitermite, antioxidant, antifungal, antituberclosis, antiplasmoid, antimalarial, hypoglycemia, antiinflammatory, antinoceptive, antipyretic, antibacterial, anticancer, antituberculosis, antiangiogenesis, antimicrobial, antifeedant and cytotoxic activities. Different types of phytochemical constituents have been successfully identified and isolated from various parts of P. sarmentosum. Therefore, the information related to the botany, ethnomedicinal uses, phytochemical constituents and pharmacological activities of P. sarmentosum were reviewed here.

• Journal of Korean Neurosurgical Society
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• 제40권6호
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• pp.412-418
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• 2006

Objective : The safety of titanium metal cages in tuberculous spondylitis has not been investigated. We evaluated the outcome and complications of titanium mesh cages for reconstruction after thoracolumbar vertebrectomy in the tuberculous spondylitis. Methods : There were 17 patients with 18 operations on the tuberculous spondylitis in this study. Sixteen patients were operated with anterior corpectomy and reconstruction with titanium mesh cage followed by posterior transpedicular screw fixations on same day, two pateints were operated by either anterior or posterior approach only. After the affected vertebral body resection and pus drainage from the psoas muscle, titanium mesh cage, filled with morselized autogenous bone, was inserted. All the patients had antituberculosis medication for 18 months. The degree of kyphosis correction and the subsidence of cage were measured in the 15 patients available at a minimum of 2 years. Outcome was assessed with various cross-sectional outcome measures. Recurrent infection was identified by serial ESR[Erythrocyte Sedimentation Rate] and CRP[Cross Reactive Protein]. Results : There was no complication from the use of a titanium mesh cage. Recurrent infection was not detected in any case. Average preoperative of $9.2^{\circ}$ was reduced to $-2^{\circ}$ at immediate postoperative period, and on final follow up period kyphotic angle was measured to be $4.5^{\circ}$. Postoperatively, subsidence was detected in most patients especially at ambulation period, however further subsidence was prevented by the titanium mesh cage. Osseous union was identified in all cases at the final follow-up. Conclusion : The cylindrical mesh cage is a successful instrument in restoring and maintaining sagittal plane alignment without infection recurrence after vertebrectomy for tuberculous spondylitis.

• Maxillofacial Plastic and Reconstructive Surgery
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• 제17권4호
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• pp.456-461
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• 1995

저자들은 좌측 악하부의 종창을 주소로 내원한 48세 여자 환자에서 임상소견과 방사선 검사 및 절제생검 조직의 병리조직학적 검사를 통해 폐의 일차적 결핵병소 없이 발생한 결핵성 경부 임파선염으로 진단하고 절제생검과 술후 isoniazid, rifampin, ethambutol을 이용한 화학요법을 시행하여 양호한 결과를 치험하였다. 비록 흔하지는 않지만 특히 젊은 성인에서 경부에 종괴가 있을 경우 감별진단시에 결핵성 경부 임파선염을 고려해야 하며, 이 질환은 재발의 가능성이 있기 때문에 주기적인 관찰과 검사가 필요할 것으로 생각된다.

• Pediatric Infection and Vaccine
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• 제20권3호
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• pp.190-196
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• 2013

결핵은 다양한 임상양상을 보이는 감염병으로 과거에 비해 많이 감소하였고 소아 결핵도 점차 줄어들고 있으나 여전히 중요한 감염병이다. 소아의 결핵은 성인과는 다른 임상적 특징을 가지며 폐외 결핵의 빈도가 성인보다 높고, 청소년의 결핵은 결핵균 감염에서 실제 질병으로 발전될 위험이 크다. 폐외 결핵 중 장결핵은 증상이 비특이적이고 다양하여 진단이 늦어질 경우 사망률 및 이환율이 높아질 수 있다. 크론병 또는 만성적인 소화기 질환과의 감별이 중요하며, 최근 대장 내시경의 발달로 감별 진단이 용이해지고 있다. 저자들은 6개월간 지속된 설사와 복통, 체중 감소와 간헐적이고 반복적인 $37.5-38^{\circ}C$의 발열로 내원한 12세 여아에게서 대장 내시경 검사를 하여 시행한 생검 조직의 PCR 검사와 조직학적 소견으로 장결핵을 진단하였고, 연이어 촬영한 흉부 방사선 상 활동성 폐결핵으로 진단되어 11개월간의 항결핵제 치료로 완치된 증례를 경험하였다.