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http://dx.doi.org/10.5667/tang.2013.0002

Review on the ethnomedicinal, phytochemical and pharmacological properties of Piper sarmentosum: scientific justification of its traditional use  

Seyyedan, Atefeh (Department of Biomedical Sciences, Faculty of Medicine and Health Sciences, Universiti Putra Malaysia)
Yahya, Farhana (Department of Biomedical Sciences, Faculty of Medicine and Health Sciences, Universiti Putra Malaysia)
Kamarolzaman, Mohammad Fauzi Fahmi (Department of Biomedical Sciences, Faculty of Medicine and Health Sciences, Universiti Putra Malaysia)
Suhaili, Zarizal (Faculty of Agriculture and Biotechnology, Universiti Sultan Zainal Abidin, Kampus Kota)
Desa, Mohd Nasir Mohd (Department of Biomedical Sciences, Faculty of Medicine and Health Sciences, Universiti Putra Malaysia)
Khairi, Hussain Mohd (Department of Biomedical Sciences, Faculty of Medicine and Health Sciences, Universiti Putra Malaysia)
Somchit, Muhammad Nazrul (Department of Biomedical Sciences, Faculty of Medicine and Health Sciences, Universiti Putra Malaysia)
Fatimah, Corazon Abdullah (Institute of Bio-IT Selangor, Universiti Selangor)
Teh, Lay Kek (Pharmacogenomics Centre (PROMISE), Faculty of Pharmacy, Universiti Teknologi MARA)
Salleh, Mohd Zaki (Pharmacogenomics Centre (PROMISE), Faculty of Pharmacy, Universiti Teknologi MARA)
Zakaria, Zainul Amiruddin (Department of Biomedical Sciences, Faculty of Medicine and Health Sciences, Universiti Putra Malaysia)
Publication Information
CELLMED / v.3, no.3, 2013 , pp. 19.1-19.32 More about this Journal
Abstract
Piper sarmentosum is a creeping herb belongs to the family of Piperaceae. It is locally known to the Malays as 'Pokok kadok' and can be found in different regions of South-East Asia including Malaysia. Ethnopharmacologically, various parts of the plant (e.g. leave, fruit and root) are widely used in Asian countries for centuries to treat different types of diseases and ailments such as hypertension, diabetes, joint aches, muscle pain, coughs, influenza, toothaches and rheumatism. Scientific findings also demonstrated different pharmacological actions of various parts of P. sarmentosum such as adulticidal, antitermite, antioxidant, antifungal, antituberclosis, antiplasmoid, antimalarial, hypoglycemia, antiinflammatory, antinoceptive, antipyretic, antibacterial, anticancer, antituberculosis, antiangiogenesis, antimicrobial, antifeedant and cytotoxic activities. Different types of phytochemical constituents have been successfully identified and isolated from various parts of P. sarmentosum. Therefore, the information related to the botany, ethnomedicinal uses, phytochemical constituents and pharmacological activities of P. sarmentosum were reviewed here.
Keywords
Piper sarmentosum; Piperaceae; ethnomedicinal uses; phytochemical constituents; pharmacological activities;
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