• 제목/요약/키워드: antiseptic

검색결과 115건 처리시간 0.021초

생리식염수 세척이 구강 소독제의 타액 내 세균 수의 변화에 미치는 영향 (Effect of saline irrigation used in combination with antimicrobial agents on salivary bacterial counts)

  • 김동주;유경환;임형섭;이성규;김수관;김학균
    • Journal of the Korean Association of Oral and Maxillofacial Surgeons
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    • 제36권3호
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    • pp.202-205
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    • 2010
  • Introduction: The aim of the present study was to investigate the effect of mechanical irrigation in combination with mouthwash of antimicrobial agents on salivary bacterial counts. Materials and Methods: This study was performed with a randomized study employing a panel of 40 healthy volunteers (20 males and 20 females) between the age of 26 and 32 years. Volunteers were randomly put in one of four treatment groups. In the first group, 0.2 mL of non-stimulatory saliva was collected from every subjective person. Then, saliva was collected after rinsing with chlorhexidine (CHX) for 1 minute. In the second group, non-stimulatory saliva was collected, and then saliva was collected after rinsing with CHX and irrigation with saline. In the third and fourth groups, the same procedures as the first and second groups were performed with povidone iodine (PVI) instead of CHX. All of these samples were cultured for 48 hours aerobically. The reduction rates of colony-forming units (CFU) were calculated for each group. The reduction rate between each group was tested statistically using student t-test. Results: Using CHX in combination with saline irrigation showed a significant decrease of the salivary bacterial CFU when compared with only using CHX.(P<0.01) And using PVI with saline irrigation showed a little decrease of the CFU when compared with only using PVI, but there was no statistical significance.(P>0.01) Conclusion: It was concluded that the CHX or PVI used with saline irrigation made the salivary bacterial counts reduced more than when CHX or PVI was used alone as an oral antiseptic agent.

목조건축물의 흰개미 방제에 대한 국외 현황조사(I) - 미국의 사례를 중심으로 - (Study of the present situation on the termite control of wooden structures(I) - Focused on the case of US)

  • 정소영
    • 보존과학연구
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    • 통권32호
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    • pp.123-136
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    • 2011
  • 우리나라에는 지중흰개미의 일종인 큐슈흰개미 1종이 분포하고 있으며, 흰개미 피해가 발견되었을 경우 훈증처리, 토양처리, 방충방부처리, 흰개미 군체제거시스템 등 4가지 방법을 적용하여 방제하고 있다. 그러나 점차적으로 흰개미에 의한 피해가 증가하고 있으므로 흰개미 피해가 심각한 미국, 일본 등 다른 나라의 피해 현황 및 방제 방법에 대해서도 조사할 필요가 있다. 본 고에서는 1950년경부터 흰개미 피해가 발생한 미국을 중심으로 흰개미 분포 현황 및 방제 체계에 대해 살펴보고자 한다. 미국에는 지중흰개미, 건재흰개미, 습재흰개미 등 다양한 종류의 흰개미가 분포하고 있어, 우리나라에 비해 흰개미에 의한 피해가 더 심하게 발생한다. 따라서 흰개미 피해를 조사하고 적절한 방제방법을 선택하는 것이 중요한데, 그 과정은 흰개미 피해 조사, 화학적 방제처리(토양 약제 처리, 흰개미 군체제거시스템), 건축물 유지보수, 주기적인 모니터링의 순서로 이루어진다. 그리고 분포하는 흰개미의 종류가 다양하기 때문에 흰개미 피해로부터 방제작업을 진행할 때도 흰개미의 특성을 고려하여 각각 다르게 적용된다. 지중흰개미에 의한 피해가 발견되었을 경우에는 건축물에 대한 기피성 또는 비기피성 살충제를 이용하여 처리하거나 흰개미 군체제거시스템을 이용하여 처리한다. 반면, 건재흰개미에 의한 피해가 발생한 경우에는 훈증처리,열처리 등을 통해 방제하고 있다.

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보존제로서 선형 1,2-알킬아미노프로판디올의 합성과 항균활성 (Synthesis of Linear 1,2-Alkylaminopropanediols as Preservatives and Antimicrobial Activity)

  • 차경온;곽상운;정국인;김영호
    • 공업화학
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    • 제33권4호
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    • pp.394-401
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    • 2022
  • 알킬 사슬의 탄소 수가 10개, 12개, 14개 및 16개인 직쇄상 1,2-알칸디올의 친수성을 향상할 목적으로 1,2-알킬아미노프로판디올(1,2-alkylaminopropanediol, 1,2-AAP)의 합성을 설계하였다. 1,2-AAP는 40 ℃ 에탄올(ethanol) 용매에서 2 h동안 3-모노클로로-1,2-프로판디올(3-monochloro-1,2-propanediol, 3-MCPD)과 10, 12, 14 및 16의 탄소 수를 갖는 선형 알킬아민 화합물과의 반응에 의해 합성하였다. 합성한 4 종류 1,2-AAP의 수율과 순도는 각각 51~58%와 85~99% 범위인 것으로 나타났다. 정제된 페이스트 또는 고체 합성물로 pH 7까지 산(HCl)을 가하여 4 종류 1,2-AAP의 아민염을 제조한 다음, 용해성과 항균효과를 시험하였다. 물에 대한 용해 농도는 1,2-데실아미노프로판디올(1,2-decylaminopropanediol, 1,2-DAP)이 100%, 1,2-도데실아미노프로판디올(1,2-dodecylaminopropanediol, 1,2-DDAP)이 50%, 1,2-테트라데실아미노프로판디올(1,2-tetradecylaminopropanediol, 1,2-TDAP)이 0.1%이었으며, 1,2-헥사데실아미노프로판디올(1,2-hexadecylaminopropanediol, 1,2-HDAP)은 용해되지 않았다. 항균 효과는 알킬 사슬의 길이가 증가할수록 향상되었다. 응용을 위해 1,2-AAP가 적용된 로션(화장품 제형)에서 보존효과를 확인한 결과 0.005~0.2% 범위의 낮은 농도에서 매우 우수한 항균력을 보였다.

보존제로서 1,2-도데실아미노프로판디올의 합성 및 1,2-알칸디올 화합물의 혼합 효과 (Synthesis of 1,2-Dodecylaminopropanediol and Its Mixing Effect with 1,2-Alkanediols as Preservatives)

  • 차경온;곽상운;정국인;김영호
    • 공업화학
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    • 제33권2호
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    • pp.179-187
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    • 2022
  • 본 연구에서는 1,2-알칸디올계 화합물의 보존력과 친수성을 향상할 목적으로 12개의 탄소 사슬 길이와 아민기를 갖는 1,2-도데실아미노프로판디올(1,2-dodecylaminopropanediol, 1,2-DDAP)의 합성을 설계하였다. 1,2-DDAP는 40 ℃의 에탄올(ethanol) 용매에서 도데실아민(dodecyl amine, DDA)과 3-모노클로로-1,2-프로판디올(3-monochloro-1,2-propanediol, 3-MCPD)의 반응에 의해 제조하였으며, 그 수율과 순도는 1:0.8의 DDA:3-MCPD 몰 비와 2 h의 반응 조건에서 각각 약 56%와 98%였다. 1,2-DDAP의 항균 효과는 1,2-옥탄디올(1,2-octanediol, 1,2-ODIOL) 또는 1,2-데칸디올(1,2-decanediol, 1,2-DDIOL)과 비교하여 10~100배 낮은 농도에서 미생물에 대한 최소억제농도와 최소살균농도 값을 나타내었다. 1,2-DDAP의 친수성을 바탕으로 1,2-DDAP로 물에 난용성인 1,2-ODIOL 또는 1,2-DDIOL을 소량 첨가하여 혼합 보존제를 제조하였다. 항균력 시험에서 혼합 보존제는 1,2-DDAP 단독사용 대비 동등 이상의 미생물 억제효과를 나타내었다. 응용을 위해 로션(화장품 제형)에서 보존 효과를 확인한 결과, 1,2-DDAP는 1,2-ODIOL 또는 1,2-DDIOL과 비교하여 0.3~0.6배의 낮은 농도에서 유사한 항균력을 나타내었다. 따라서 1,2-DDAP의 단독 사용 및 1,2-ODIOL 또는 1,2-DDIOL을 소량 혼합하여 사용하는 것이 제품 내 보존제에 대한 좋은 대안으로 사용될 수 있을 것이다.

젖소 유방염 관리에 따른 세균 및 체세포수 등급 실태 조사 분석 (Analytical studies of bovine mastitis management by standard plate counts(SPC) and somatic cell counts(SCC))

  • 허정호;정명호;박영호;조명희;이주홍
    • 한국동물위생학회지
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    • 제21권3호
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    • pp.285-300
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    • 1998
  • 1. The number of average milking cows, clinical forms of mastitis, mastitis-developing cows, and cows killed by mastitis a year were 25.7, 1.8(7%), 6.3(26%), and 2.7(10.1%)heads, respectively. The annual grade changes of standard plate counts(SPC) and somatic cell counts(SCC) showed the grade 1A of SPC diminished sharply from April to August, we think it was due to the lack of proper management in farming season and the grade 3 of SCC indirectly influenced increased in huge during August. 2. The average number of parturitions of farms was 2.3, but 50% of below 1 parturition were 22 farms(31%), 50% of above 3 parturitions were 16(23%) out of 71 farms. According to grades of the number of parturitions of milking cows per each farm, the farms' grades recording 3 parturitions and 50% were little bit excellent. 3. The actual situation research of foremilking CMT revealed 35 out of 74 farmer didn't do CMT Among them(35 out of 74 farmers), 80% did not test thanks to the troublesome process of the CMT. SCC grade 3, among farms who did foremilking CMT once or twice a month and who did not were 29% and 40% respectively and SPC grade 1A were 55% and 9%, respectively. 4. The research of actual situation on milking management let us know 29 farms(39%) did not do lastmilking, 37 farms(49%) usually did overmilking, and 34 farms(46%) did milking for 4 or 5 minutes. Grades according to average requiring times of milking showed SCC grade 1 of farms milking within 7 minutes was 11% and SPC grade 1A was 34%, on the other side, farms milking more than 7 minutes were 0% in SCC grade 1 and 13% in SPC grade 1A. Grades according to the starting time of milking after rubbing teats showed SPC grade 1A of farms starting milking at about 1 minute and over 2 minutes were 50% and 20%, respectively. 5. The research of actual situation on hygienic milking management uncovered 65 farms(88%) were using one towel which was used in washing teats and udders to wash more than 3 to 4 cows, and 53 farms(72%) were using one dried towel to dry udders not for each cow but for more than 3 to 4 cows after washing. Also, on milking turns disclosed 30 farms(40%) were milking cows in the order of incoming without isolation of a dominant group. According to grades of towels used in washing teats and udders, farms using a towel for each cow were 56% and a towel for over 3 cows were 31% in SPC grade 1A. According to using-or-not grades of dried towels after washing udders, farms using a towel for each cow were 79% and a towel for over 3 cows were 21% in SPC grade 1A. 6. Farms doing teat-dipping before milking were 7(10%), not doing teat-dipping after milking, or doing sometimes were 9(12%), and doing right after milking were 57(77%). And farms doing teat-dipping after dry cows and before delivery were 21(28a ). Farms using bethadine as an antiseptic solution were 70(95%), 40 farms(59%) diluted it with water as weak as 5 to 10 times, and on drying cows 64 farms(87%) slowly did it more than 2 days. Grade 1A of SPC of farms doing teat-dipping at every milking was 38%, farms doing occasionally or not was 33%, and farms doing it right after milking was 37% and doing after milking more than 5 cows was 20%. Grade 1A of SPC among farms diluting bethadine 5 times and diluting 5 to 10 times with water were 36% and 33%, respectively, and Grade 3 of SCC were 35% and 32%, respectively. 7. Studies on nonlactating period medical treatment, as the cows were on dry, 54 farms treated with their own hands.73 farms(98%) had bovine mastitis treated for themselves. And on applying medicines against mastitis, 55 farmers chose them on the basis of their own experience, 42 farms(57%) were treated more than 3 days. 41 farms(55%) dumped away the mastitis infected milk separately, 24 farms(32%) were feeding and milking at the same time. 8. Fifty-six farms(76%) always washed and disinfected milking machines after milking. Farms using the milking machines at low, or variable vacuum pressures, or at the vacuum pressure, set at the moment of its installation were 31(42%), and farms that did not know pulsation ratio were 27(37%). Farms changing liners when they were torn 8(11%), 58 farms(78%) said they checked milking system when there were wrong with them, 31 farms(42%) changed milking hoses when they found out problems, and 42 farms(57%) cleaned vacuum and milking systems when they felt dirty. The SPC grade 1A of farms washing and sterilizing milking machines was 38% and farms only washing was 28%.

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