• Journal of Physiology & Pathology in Korean Medicine
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• v.26 no.1
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• pp.53-58
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• 2012

The aim of this study was to investigate the antimicrobial, antiperspirant and deodorant effect of herb mixtures including Schisandra chinensis(SC). This herb mixtures including Schisandra chinensis was made of Astragalus membranaceus(AM), Triticum aestivum(TA), Atractylodes japonica(AJ) and peppermint essential oil extracted from Mentha piperita(MP). We examined antimicrobial activity, antiperspirant activity and L-leucine dehydrogenase activity of the herbal extracts. We found that the mixture of SC and MP have the best antimicrobial effects on B. subtilis subsp. spizizenii and mixture of SC, AJ, AM and TA have best antiperspirant effect. Moreover, the combination of SC and AM showed the most inhibitory effect on L-leucine dehydrogenase activity. These results suggested that the herb mixtures Including Schisandra chinensis have good antimicrobial and antiperspirant effects.

• Proceedings of the SCSK Conference
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• 2003.09a
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• pp.232-257
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• 2003

It has been shown that transparent microemulsion gels of flexibly adjustable viscosity containing less than 10％ w/w surfactants can be obtained just by cooling down through a new 1-step preparation procedure (via 4 different in-situ colloidal systems) using PIT-technology with a range of emulsifiers, co-emulsifiers and lipids. They can be used for a wide scope of applications. Specific examples have been given with antiperspirant formulas that proof the stability of these thickened microemulsions even with high content of electrolytes and low pH. We propose that the structure of these microemulsion gels can be described by cross-linking of nano-fine oil droplets via an ABA-triblock copolymer. A new generation of transparent antiperspirant roll-ons with significantly improved skin tolerance can now be formulated as an attractive alternative to alcohol-based products.

• Proceedings of the SCSK Conference
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• 2003.09b
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• pp.110-116
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• 2003

We have developed a high performance powder, which has a quenching efficacy not only for short-chain fatty acids and amines, but also for vinyl ketones (l-octen-3-one, cis-l,5-octadien-3-one), newly found as other key compounds in axillary malodor. By investigating various powders known to have a quenching efficacy, we finally developed a highly porous silica bead containing magnesium oxide. We found that the superior deodorant effect performed by this powder was the result of multiple effects due to both an excellent physical adsorption capability from its high porosity and a specific adsorption of vinyl ketones by magnesium in the powder. An antiperspirant formulation containing both this powder and a Morus alba extract showed good efficacy as a deodorant.

• Korean Journal of Medicinal Crop Science
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• v.17 no.4
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• pp.233-237
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• 2009

Astragalus membranaceus has a long history of medicinal use in Chinese herbal medicine. It has been shown to have immunostimulant, tonic, antioxidant, antiperspirant, diuretic, anti-diabetic, expectorant properties, and a supplementary medicine during cancer therapy. In this study, we investigated the effect of anti-oxidation of Astragalus membranaceus root extract. The anti-oxidative activities of water, 80% methanol, and 100% methanol extracts from Astragalus membranaceus were analyzed by DPPH free radical scavenging activity, Superoxide dismutase-like activity, reducing power, and crude ash. The water extract demonstrated to be more effective than methanol extract for a DPPH radicals scavenging activities and reducing power. Superoxide dismutase-like activity showed higher efficiency in 80% methanol extract. Our results indicate that Astragalus membranaceus extracts could be used as a source of antioxidant ingredients in the food industry.

• Journal of Food Hygiene and Safety
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• v.21 no.2
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• pp.100-106
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• 2006

The use of underarm and body care cosmetics with oestrogenic chemical excipients (particularly the parabens) and the hypothesized association with breast cancer incidence, particularly in women. It is noted that the type of cosmetic product is irrelevant (e.g. antiperspirant/deodorant versus body lotion, moisturizers or sprays versus creams) and attention must focus on issues of actual exposure to chemicals through continued dermal application of body care products and the endocrine/hormonal activity and toxicity of the chemicals in the formulations. To evaluate the estrogenic activities of parabens such as ethylparaben, butylparaben, propylparaben, isobutylparaben and isopropylparaben, we used recombinant yeasts containing the human estrogen receptor [Saccharomyces cerevisiae ER+LYS 8127], human breast cancer MCF-7 cell lines and human estrogen receptor ${\alpha}\;and\;{\beta}$. In E-screen assays, isopropylparaben is the most estrogenic paraben, and in ER competition assay, isobutylparaben is the most estrogenic paraben. We evaluated isopropylparaben was most active in the recombinant yeast assay, followed by propylparaben, ethylparaben, isobutylparaben and butylparaben. Results from this study demonstrate that parabens are observed in human endocrine system. Therefore, we have shown that the parabens is induced the estrogenic activities similar to $17{\beta}$-estradiol and Bisphenol-A.