• Title/Summary/Keyword: antioxidants

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Protective Effects of a Ginseng Component, M altol(2- M ethyl-3- Hydroxy-4- Pyrone) against Tissue Damages Induced By Oxygen Radicals

  • Jae-Gook Shin;Jon
    • Proceedings of the Ginseng society Conference
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    • 1990.06a
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    • pp.45-48
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    • 1990
  • Maltol(2-methyl-3-hydroxy-r-pyrone), a component known to be present in Korean Ginseng root showed an antioxidant action but its potency as an antioxidant was low; about 1150th that of other antioxidants such as p-phenylenediamine , BHA and BHT. However, maltol was able to protect the oxidation adamants in biological systems such as adriamycin-induced membrane damage in isolated cardiomyocytes, parquet-induced toxicities in isolated hepatocytes and repercussion injury in isolated hearts. The antioxidant action of maltol was also shown to be effective in vivo. The antioxidant action of this compound was probably due to the removal of hydroxyl radicals. In view of the roles of oxygen radical in various pathological processes, Korean Ginseng root, which contains several antioxidants including maltol, is expected to have beneficial efforts on the oxygen radical-involved processes. Keywords Maltol, Oxygen free radicals, Lipid preoccupation, Repercussion injury and Korean ginseng

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Are antioxidants induced by UV-B exposure in a leaf of spinach transported into another leaf\ulcorner

  • Yonemura, Takeshi
    • Journal of Photoscience
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    • v.9 no.2
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    • pp.442-444
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    • 2002
  • Seedlings of spinach (Spinacia oleracea L. "King of Denmark" and "Minsterland") were grown with or without supplemental UV-B under field conditions for five or nine days when their fifth or sixth leaves were expanding. Except two leaves which were just expanded and expanding, all other leaves of each seedling were removed before tested. One of these two leaves was exposed to UV-B irradiation and the other leaf was covered with lumiror film (no transmission below 320 nm) to prevent it from UV-B exposure. l,l-diphenyl-2-picrylhydrazyl scavenging activities (antioxidative activity) in leaves without covers were increased according to UV-B doses they were exposed to. And removal of UV-B exposure with lumiror decreased foliage antioxidative activities. This increase or decrease of activities in leaves did not dependent on the UV-B doses their paired leaves were exposed to in both two cultivars. The results demonstrated that spinach foliage antioxidants induced by UV-B exposure were not transported into another leaf.

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Antioxidative Effect of Aloe (Aloe arborescences) Extracts on Linoleic Acid and Soybean Oil (Aloe추출물의 유지에 대한 항산화 효과)

  • 우나리야;안명수;이기영
    • Korean journal of food and cookery science
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    • v.11 no.5
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    • pp.536-541
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    • 1995
  • The antioxidative effect of Aloe extracts on 0.1 M-linoleic acid was compared with some commercial antioxidants during storage at 50${\pm}$2$^{\circ}C$ for 20 hours, and on soybean oils at 60${\pm}$2$^{\circ}C$ for 30 days. In the oxidation of linoleic acid, antioxidative effects of various Aloe extracts and other antioxidants were shown as following orders: 3% Aloe methanol extract > 1% Aloe methanol extract > 0.02% BHT > 3% Aloe ethyl acetate extract > 0.5% Aloe methanol extract > 0.02%-Tocopherol>Aloe methanol extract, 0.1, 0.02% > Aloe ethylacetate extract, 1, 0.5, 0.1, 0.02% > control, while in the oxidation of soybean oil, l% Aloe methanol extract > 0.02% BHT > 3% Aloe methanol extract > 0.02%-Tocopherol>control.

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Use of Complementary and Alternative Medicine Among Breast Cancer Survivors in Taiwan

  • Wang, Hsiu-Ho;Chung, Ue-Lin
    • Asian Pacific Journal of Cancer Prevention
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    • v.13 no.9
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    • pp.4789-4792
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    • 2012
  • Aims: The purpose of this study was to investigate complementary and alternative medicine use among breast cancer survivors in Taiwan. Materials and Methods: This study employed a descriptive research design approach to detail the CAM use among the target population. Convenience sampling was used along with a structured questionnaire. Results: A total of 230 breast cancer survivors completed the use CAM scale. Prayer, reading books, taking antioxidants, eating various grains, and maintaining a vegetarian diet proved to be the five most frequently used CAM practices among patients in our study. More than 50.0% of the participants reported praying occasionally. More than 40.0% of participants read books occasionally, and 38.7% stated that they occasionally take antioxidants. Conclusions: These results provide more insight into CAM use for nurses who care for breast cancer patients.

Functional Ingredients of Maize and Their Variation (옥수수 기능성 물질의 종류와 변이)

  • Kim Sun Lim;Choi Byung Han;Park Seung Ue;Moon Hyun Guey
    • KOREAN JOURNAL OF CROP SCIENCE
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    • v.41 no.spc1
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    • pp.46-68
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    • 1996
  • The objective of this report is to review the up to present papers including 79 references about functional ingredients in maize and their variations. Maize is a good source of such antioxidants as ${\alpha}-,\;{\gamma}-tocopherols,\;{\alpha}-,\;{\beta}-carotene,\;{\beta}-cryptoxanthin$, zeaxanthin, quercetin and chlorogenic acid. Unsaponifiable standard extracts of Zea mays L. (ZML) have a beneficial effect on various dental diseases. Flavonoids, flavonoid biosynthetic pathway and their controling genes were also reviewed in this report. Flavonoids are required for successful fertilization in maize pollen, and maysin has a potent antibiotic activities to earworm and fall armyworm in maize silks. Maize silks have been used in traditional medicine for diuretic, vascular diseases and diabetes, etc. and boiling water extracts of maize silk have hemodynamic effects, but their ingredients still remain obscure.

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Synthesis of 6- Hydroxy-7 -methoxychroman-2-carboxylic Acid Dialkylaminoalkylamides (6-하이드록시-7-메톡시크로만-2-카복실산 디알킬아미노알킬아마이드 합성)

  • Kwak, Jae-Hwan;Lee, Keum-Ho;Jung, Jae-Kyeong;Cho, Jung-Sook;Lee, Hee-Soon
    • YAKHAK HOEJI
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    • v.50 no.5
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    • pp.322-325
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    • 2006
  • In the course of developing novel antioxidants, we synthesized four of 6-hydroxy-7-methoxy-4-oxochroman-2carboxylic acid dialkylamides (3a-d) $(13{\sim}18%)$ and four of 6-hydroxy-7-methoxychroman-2-carboxylic acid dialkylamides (4a-d) $(52{\sim}89%)$, incorporating the basic amine functionality. None of these compounds exhibited significant antioxidant activity possibly due to the hydrophilic character of the basic amine side chains.

Protective Effects of a Ginseng Component, Malto1(2-Mlethyl-3-Hydrox)-4-Pyrone) against Tissue Damages Induced By Oxygen Radicals (활성산소에 의한 조직손상에 미치는 인삼성분의 보호효과)

  • Jae-Gook Shin;Jon
    • Journal of Ginseng Research
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    • v.14 no.2
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    • pp.187-190
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    • 1990
  • Maltol(2-methyl-3-hydroxy-r-pyrone), a component known to be present in Korean Ginseng root showed an antioxidant action but its potency as an antioxidant was low: about 1150th that of other antioxidants such as pphenylenediamine, BHA and BHT. However, maltol was able to protect the oxidation damages in biological systems such as adriamycin-induced membrane damage in isolated cardiomyocytes, paraquat-induced toxicities in isolated hepatocytes and reperfusion injury in isolated hearts. The antioxidant action of maltol was also shown to be effective in vivo. The antioxidant action of this compound was probably due to the removal of hydroxyl radicals. In view of the roles of oxygen radical in various pathological proceises, Korean Ginseng root which contains several antioxidants including maltol is expected to have beneficial effects on the oxygen radical-involved processes.

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Problems and Possible Solutions about Feed Fungi and Mycotoxins (사료 중의 곰팡이와 곰팡이 독소에 대한 문제점과 가능한 대책)

  • 남기홍
    • Korean Journal of Poultry Science
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    • v.21 no.2
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    • pp.113-117
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    • 1994
  • Of the 200, 000 known species of molds, only 50 or 60 are known to be harmful to humans or livestock. Certain fungi that grow on grains and grasses can produce chemical substances called mycotoxins that adversely affect performance in poultry. There are several methods of preserving feed ingredients. The list includes: drying, antioxidants, mold inhibitors, organic acids, phosphates, cooking or toasting, fat extraction, blending and fermenting. Mold inhibitors are manufactured to inhibit mold growth and prevent the production of toxic substances. They are fungistats and not fungicides, that is, they only stop the growth of molds. Practical and cost-effective methods to detoxify mycotoxin containing feedstuffs are in great demand. 0.5% hydrated sodium calcium aluminosilicate added to the diet protected chicks from the deleterious effects of aflatoxin-contaminated feed. The dietary addition of antioxidants and methionine also significantly diminished the negative effects on body weight in chicks toxicated with 3.0 ppm aflatoxin B1.

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Effects of Antioxidants on the Antioxidant and Apoptosis Genes Expression of IVM/IVF Hanwoo Embryos

  • Jang, H.Y.;Parkm C.K.;Cheong, H.T.;Kim, C.I.;Yim, S.V.;Kim, S.S.;Park, D.H.;Yang, B.K.
    • Proceedings of the KSAR Conference
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    • 2002.06a
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    • pp.69-69
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    • 2002
  • To investigate the effects of two antioxidants, aesculeitin and taurine, expression of apoptosis related genes and antioxidant enzyme gene in preimplantation Hanwoo embryos was determined by modified semi-quantitative single cell RT-PCR. Hanwoo embryos derived from in vitro maturation /in vitro fertilization were cultured in 5% CO₂ and 5% O₂ in CR₁aa medium at 37℃. Aesculeitin and taurine were added to medium at concentration of l㎍/㎖ and 2.5mM, respectively. (omitted)

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The Oxidative Stress in Cigarette Smokers and Antioxidant Vitamins

  • Aewha, Ha;Harris, Natholyn D.
    • Journal of Nutrition and Health
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    • v.30 no.9
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    • pp.1102-1108
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    • 1997
  • The purpose of this study was to find the extent of lipid peroxidation of erythrocytes in cigarette smokers, and to determine the relative effectiveness of $\beta$-carotene, canthaxanthin , and $\alpha$-tocopherol as antioxidants. Thirty smokers and 30 nonsmokers participated in this study . No significant differences according to age, sex, and height were shown. Cigarette smokers in this study had higher hemoglobin concentrations and more oxidation of hemoglobin than non-smokers. In addition, the erythrocytes of cigarette smokers had significantly higher MDA concentrations than crythrocytes of nonsmokers, which suggests that smokers may have tocopherol were studied in vitro by measuring the concentration of malondialdehyde(MDA) and precent hemolysis of erythrocytes. The addition of any antioxidant to erythrocytes significantly decreased MDA concentrations(p<0.05) while antioxidants showed nonsignificant inhibition of hemolysis. Among the antioxidant used in this study, canthaxanthin showed the greatest inhibition of both lipid peroxidationand hemolysis. Meanwhile, $\alpha$-tocopherol showed potent inhibition of lipid peroxidation, but not of hemolysis.

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