• Title/Summary/Keyword: anti-soil

Search Result 141, Processing Time 0.026 seconds

In-vitro Anti-thrombosis Activity of Sphagnum palustre (수태의 항혈전 활성)

  • Lee, Ye-Seul;Jung, Su-Jin;Kim, Mi-Sun;Sohn, Ho-Yong;Jung, In-Chang
    • Microbiology and Biotechnology Letters
    • /
    • v.42 no.4
    • /
    • pp.417-421
    • /
    • 2014
  • Sphagnum palustre (SP), a species of moss belong to the Sphagnaceae family, is used as a dwarfed potted plant, in diapers, bandages, and soil additives. Although, SP can be found all over the world and is very cheap, the study of SP components and bioactivities are still at a rudimentary stage. In this study, the hot-water extract of SP (HWSP) and its subsequent organic solvent fractions were prepared, and their in-vitro anti-thrombosis activities were evaluated. The results showed that the water residue of HWSP has a strong anti-coagulation activity with significant extensions of thrombin time, and platelet aggregation activity. Our results suggest that the SP has the potential to be a novel resource for anti-thrombosis agents. This report provides the first evidence of the anti-thrombosis activity of SP.

The Characteristics of Antitumor Agent Isolated from Streptomyces sp.409 (Streptomyces sp.409 에서 분리한 항암활성 물질의 특징)

  • 장영수
    • YAKHAK HOEJI
    • /
    • v.44 no.5
    • /
    • pp.478-487
    • /
    • 2000
  • This study was carried out to find new anti-tumor agent producing microbe and to characterize the anti-tumor agent produced from the microbe. Purified compound that has a high cytotoxicity against tumor cell-lines could be obtained from the broth culture filtrates of Streptomyces sp.409 strain isolated from soil in Korea. The in vitro cytotoxicity the in vivo evaluation of acute toxicity the safety assessment of the anti-tumor compounds and the taxonomic characteristics of the anti-tumor agent were measured. The antitumor compound 1 and 2 were obtained from the broth culture filtrates of Streptomyces sp.409 strain. The cytotoxicity of the compound 1 against tumor cell-line P388D$_1$ showed almost 4.5 times higher than that of adriamycin. However in the cytotoxicity against normal cell line Vero E6, adriamycin showed adversely 4 times higher than the compound 1 ($IC_{50}$/ value: 228.7 $\mu\textrm{g}$/$m\ell$). In comparison study with compound 1 and compound 2 in the in vitro cytotoxin productivity against tumor cell lines, $IC_{50}$/ value of the compound 1 was 0.25 $\mu\textrm{g}$/$m\ell$ in tumor cell line P388D$_1$and 0.53 $\mu\textrm{g}$/$m\ell$ in tumor cell-line L1210, and that of the compound 2 was 7.18 $\mu\textrm{g}$/$m\ell$ and 35.71 $\mu\textrm{g}$/$m\ell$, respectively; LD$_{50}$ value of the compound 1 in the in vivo acute toxicity in mice was 22.62 $\mu\textrm{g}$/kg body weight. These results suggest that compound 1 purified from Streptomyces sp. 409 has anti-tumor activity and will be developed as an anti-tumor drug.g.

  • PDF

Identification of Jet fuel (JP-8) in Petroleum Hydrocarbon Contaminated Soil through the Qualitative Analysis of Antioxidants (유류 오염 토양 중 산화방지제 정성 분석을 통한 항공유(JP-8) 유종 판별)

  • Kim, Yonghun;Lee, Goontaek;Jang, Hanjeon;Jo, Yunju;Kim, Moongun;Choi, Jaeho;Kang, Jiyoung
    • Journal of Soil and Groundwater Environment
    • /
    • v.27 no.4
    • /
    • pp.37-48
    • /
    • 2022
  • Accurate analysis of petroleum hydrocarbons in soil is an important prerequisite for proper source tracking of contamination. Identification of petroleum compounds is commonly carried out by peak pattern matching in gas chromatography. However, this method has several technical limitations, especially when the soils underwent biological, physical and chemical transformation. For instance, it is very difficult to distinguish jet fuel (JP-8) from kerosene because JP-8 is derivatized from secondary reaction between chemical agents (e.g. anti-oxidants, antifreezer and so on) and kerosene. In this study, an alternative method to separately analyze JP-8 and kerosene in the petroleum hydrocarbon contaminated soil was proposed. Qualitative analyses were performed for representative phenolic antioxidants [2,6-di-tert-butyl phenol (2,6-DTBP), 2,4-di-tert- butylphenol(2,4-DTBP), 2,6-di-tert-butyl-4-methyl phenol (2,6-DTBMP)] using a two dimensional gas chromatograph mass spectrometer (2D GC×GC-TOF-MS). This qualitative analysis of antioxidants in soil would be a useful complementary tool for the peak pattern matching method to identify JP-8 contamination in soil.

An Establishment of Database for Effective Design of Anti-Frost Heave Layer using Field Data (도로포장의 효율적 동상방지층 설계를 위한 현장 계측자료의 데이터베이스(DB) 구축)

  • Kim, Nak-Seok;Nam, Young-Kug;Cho, Gyu-Tae;Lee, Bum-Woo
    • Journal of the Korean Society of Hazard Mitigation
    • /
    • v.11 no.3
    • /
    • pp.43-47
    • /
    • 2011
  • Korea has seasonal weathers which result in the frosting of soil in winter times, and the thawing of soil in spring. These climate characteristics result in the damaging of pavements, due to the repeated freezing and thawing of road pavements during winter and spring. In order to reduce these pavement damages, anti-frost heave layers are being specially installed, however it is being applied based on foreign researches, and therefore result in the waste of national budget. With this study, a database system was constructed for effective management and monitoring of measured temperatures and function data of 2 meters below the embankment, cut slope, and the cutting-embankment boundary, which are 15 regions picked by the frost index diagram. As the study result, an effective storage and management-purpose database was established for easy data searching and downloading for the pavement design engineers.

Anti-seismic behavior of composite precast utility tunnels based on pseudo-static tests

  • Yang, Yanmin;Tian, Xinru;Liu, Quanhai;Zhi, Jiabo;Wang, Bo
    • Earthquakes and Structures
    • /
    • v.17 no.2
    • /
    • pp.233-244
    • /
    • 2019
  • In this work, we have studied the effects of different soil thicknesses, haunch heights, reinforcement forms and construction technologies on the seismic performance of a composite precast fabricated utility tunnel by pseudo-static tests. Five concrete specimens were designed and fabricated for low-cycle reciprocating load tests. The hysteretic behavior of composite precast fabricated utility tunnel under simulated seismic waves and the strain law of steel bars were analyzed. Test results showed that composite precast fabricated utility tunnel met the requirements of current codes and had good anti-seismic performance. The use of a closed integral arrangement of steel bars inside utility tunnel structure as well as diagonal reinforcement bars at its haunches improved the integrity of the whole structure and increased the bearing capacity of the structure by about 1.5%. Increasing the thickness of covering soil within a certain range was beneficial to the earthquake resistance of the structure, and the energy consumption was increased by 10%. Increasing haunch height within a certain range increased the bearing capacity of the structure by up to about 19% and energy consumption by up to 30%. The specimen with the lowest haunch height showed strong structural deformation with ductility coefficient of 4.93. It was found that the interfaces of haunches, post-casting self-compacting concrete, and prefabricated parts were the weak points of utility tunnel structures. Combining the failure phenomena of test structures with their related codes, we proposed improvement measures for construction technology, which could provide a reference for the construction and design of practical projects.

The Frost Heaving Characteristics of Subgrade Soils Using Laboratory Freezing System (실내동결시스템을 이용한 노상토의 동상 특성)

  • Shin, Eun-Chul;Ryu, Byung-Hyun;Park, Jeong-Jun
    • International Journal of Highway Engineering
    • /
    • v.12 no.2
    • /
    • pp.71-79
    • /
    • 2010
  • The influence of fines of the frost susceptibility of subgrade soils were established by laboratory freezing system test simulating closely the thermal conditions in the field. During the winter season, the climate is heavily influenced by the cold and dry continental high pressure. Because of siberian air mass, the temperature of January is $-6{\sim}-7^{\circ}C$ on average. This chilly weather generate the frost heaving by freezing the moisture of soil and damage potential of the road structure. In the freezing soil, the ice lenses increase the freeze portion of soil by absorbing the ground water with capillary action. However, the capillary characteristics differ from the sort of soil on the state of freezing condition. In the current design codes for anti-freezing layer, the thickness of anti freezing layer is calculated by freezing depth against the temperature condition. Therefore, they have a tendency of over-design and uniform thickness without the considerations of thermal stability, bearing capacity and frost susceptibility of materials. So, it is essential for studying the appropriateness and bearing capacity besides the seasonal and mechanical properties of pavement materials to take a appropriate and reasonable design of the road structure. In this Paper, the evaluation of frost susceptibility was conducted by means of the mechanical property test and laboratory freezing system apparatus. The temperature, heaving amount, heaving pressure and unfrozen water contents of soil samples, the subgrade soils of highway construction site, were measured to determine the frost susceptibility.

Synthesis and Surface Characteristics of Novel Oligomeric Silane with Perfluoropolyether (과불소 폴리에테르 포함 새로운 실란형 올리고머의 합성과 표면 특성)

  • Park, Eun-Young;Lee, Sang-Goo;Ha, Jong-Wook;Park, In-Jun;Lee, Soo-Bok;Lee, Yong-Taek
    • Polymer(Korea)
    • /
    • v.32 no.4
    • /
    • pp.397-402
    • /
    • 2008
  • Perfluoropolyether(PFPE) has been widely applied in industry because of its very excellent properties of very high contact angle and low surface energy, good lubricant property and antifouling property. But the difficulty to synthesize PFPE has limited the research on this field. In this study, the novel silicon-containing oligomer with perfluoropolyether moiety was synthesized, and the structure was characterized by $^{19}F$-NMR and $^1H$-NMR. The surface properties of contact angle, sliding angle, and soil release property were investigated. The results show that PFPE in this study can be utilized as an anti-smudge coating material because it shows lower sliding angle and better soil release property than commercial products.

Water-induced changes in mechanical parameters of soil-rock mixture and their effect on talus slope stability

  • Xing, Haofeng;Liu, Liangliang;Luo, Yong
    • Geomechanics and Engineering
    • /
    • v.18 no.4
    • /
    • pp.353-362
    • /
    • 2019
  • Soil-rock mixture (S-RM) is an inhomogeneous geomaterial that is widely encountered in nature. The mechanical and physical properties of S-RM are important factors contributing towards different deformation characteristics and unstable modes of the talus slope. In this paper, the equivalent substitution method was employed for the preparation of S-RM test samples, and large-scale triaxial laboratory tests were conducted to investigate their mechanical parameters by varying the water content and confining pressure. Additionally, a simplified geological model based on the finite element method was established to compare the stability of talus slopes with different strength parameters and in different excavation and support processes. The results showed that the S-RM samples exhibit slight strain softening and strain hardening under low and high water content, respectively. The water content of S-RM also had an effect on decreasing strength parameters, with the decrease in magnitude of the cohesive force and internal friction angle being mainly influenced by the low and high water content, respectively. The stability of talus slope decreased with a decrease in the cohesion force and internal friction angle, thereby creating a new shallow slip surface. Since the excavation of toe of the slope for road construction can easily cause a landslide, anti-slide piles can be used to effectively improve the slope stability, especially for shallow excavations. But the efficacy of anti-slide piles gradually decreases with increasing water content. This paper can act as a reference for the selection of strength parameters of S-RM and provide an analysis of the instability of the talus slope.

Design of Replacement Method on Anti-freeze Process of L Type Retaining Wells (L형 옹벽의 동상대책에 있어서 치환공법의 설계)

  • Rui, Da-Hu;Kim, Young-Su;Suzuki, Teruyuki
    • Journal of the Korean Geotechnical Society
    • /
    • v.25 no.9
    • /
    • pp.19-27
    • /
    • 2009
  • In order to investigate anti-freeze process of precast concrete L-type retaining walls in cold regions, test walls were installed in the campus of Kitami Institute of Technology (KIT, Hokkaido, Japan). The wall consists of following three sections, i) back filled with frost susceptible clay soil, ii) using thermal insulation material, and back filled with frost susceptible soil, iii) back filled with frost-unsusceptible soil. The freezing front distribution and ground temperature within the backfill were observed and deflections of the walls were measured over three freeze-thaw seasons. Some understanding of the mechanisms of the build-up of frost heave pressure was gained, and the effectiveness of replacement method was observed. A simulation was performed to predict the shape of the freezing front in the backfill behind L-type walls with various cross sections. These findings were employed to propose a method for determining the appropriate zone to be replaced with frost unsusceptible backfill material in cold regions.

Advantages and disadvantages of renewable energy-oil-environmental pollution-from the point of view of nanoscience

  • Shunzheng Jia;Xiuhong Niu;Fangting Jia;Tayebeh Mahmoudi
    • Advances in concrete construction
    • /
    • v.16 no.1
    • /
    • pp.69-78
    • /
    • 2023
  • This investigation delves into the adverse repercussions stemming from the impact of arsenic on steel pipes concealed within soil designated for rice cultivation. Simultaneously, the study aims to ascertain effective techniques for detecting arsenic in the soil and to provide strategies for mitigating the corrosion of steel pipes. The realm of nanotechnology presents promising avenues for addressing the intricate intersection of renewable energy, oil, and environmental pollution from a novel perspective. Nanostructured materials, characterized by distinct chemical and physical attributes, unveil novel pathways for pioneering materials that exert a substantial impact across diverse realms of food production, storage, packaging, and quality control. Within the scope of the food industry, the scope of nanotechnology encompasses processes, storage methodologies, packaging paradigms, and safeguards to ensure the safety of consumables. Of particular note, silver nanoparticles, in addition to their commendable antibacterial efficacy, boast anti-fungal and anti-inflammatory prowess, environmental compatibility, minimal irritability and allergenicity, resilience to microbial antagonism, thermal stability, and robustness. Confronting the pressing issue of arsenic contamination within both environmental settings and the food supply is of paramount importance to preserve public health and ecological equilibrium. In response, this study introduces detection kits predicated upon silver nanoparticles, providing an expeditious and economically feasible avenue for identifying arsenic concentrations ranging from 0.5 to 3 ppm within rice. Subsequent quantification employs Hydride Atomic Absorption Spectroscopy (HG-AAS), which features a detection threshold of 0.05 ㎍/l. A salient advantage inherent in the HG-AAS methodology lies in its capacity to segregate analytes from the sample matrix, thereby significantly reducing instances of spectral interference. Importantly, the presence of arsenic in the soil beneath rice cultivation establishes a causative link to steel pipe corrosion, with potential consequences extending to food contamination-an intricate facet embedded within the broader tapestry of renewable energy, oil, and environmental pollution.