• 제목/요약/키워드: anti- evolution

검색결과 51건 처리시간 0.03초

New insights on the origin of multiple stellar populations in globular clusters

  • 김재연;이영욱
    • 천문학회보
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    • 제43권1호
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    • pp.46.1-46.1
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    • 2018
  • In order to investigate the origin of multiple stellar populations in the halo and bulge of the Milky Way, we have constructed chemical evolution models for the low-mass proto-Galactic subsystems such as globular clusters. Unlike previous studies, we assume that supernova blast waves undergo blowout without expelling the pre-enriched gas, while relatively slow winds of massive stars, together with the winds and ejecta from low and intermediate mass asymptotic-giant-branch stars, are all locally retained in these less massive systems. We find that the observed Na-O anti-correlations in metal-poor GCs can be reproduced when multiple episodes of starbursts are allowed to continue in these subsystems. A specific form of star formation history with decreasing time intervals between the stellar generations, however, is required to obtain this result, which is in good agreement with the parameters obtained from our stellar evolution models for the horizontal-branch. The "mass budget problem" is also much alleviated by our models without ad-hoc assumptions on star formation efficiency and initial mass function. We also applied these models to investigate the origin of super helium-rich red clump stars in the metal-rich bulge as recently suggested by Lee et al. (2015). We find that chemical enrichments by the winds of massive stars can naturally reproduce the required helium enhancement (dY/dZ = 6) for the second-generation stars. Disruption of proto-globular clusters in a hierarchical merging paradigm would have provided helium enhanced stars to the bulge field.

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Sequence Analysis and Potential Action of Eukaryotic Type Protein Kinase from Streptomyces coelicolor A3(2)

  • Roy, Daisy R.;Chandra, Sathees B.C.
    • Genomics & Informatics
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    • 제6권1호
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    • pp.44-49
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    • 2008
  • Protein kinase C (PKC) is a family of kinases involved in the transduction of cellular signals that promote lipid hydrolysis. PKC plays a pivotal role in mediating cellular responses to extracellular stimuli involved in proliferation, differentiation and apoptosis. Comparative analysis of the PKC-${\alpha},{\beta},{\varepsilon}$ isozymes of 200 recently sequenced microbial genomes was carried out using variety of bioinformatics tools. Diversity and evolution of PKC was determined by sequence alignment. The ser/thr protein kinases of Streptomyces coelicolor A3 (2), is the only bacteria to show sequence alignment score greater than 30% with all the three PKC isotypes in the sequence alignment. S.coelicolor is the subject of our interest because it is notable for the production of pharmaceutically useful compounds including anti-tumor agents, immunosupressants and over two-thirds of all natural antibiotics currently available. The comparative analysis of three human isotypes of PKC and Serine/threonine protein kinase of S.coelicolor was carried out and possible mechanism of action of PKC was derived. Our analysis indicates that Serine/ threonine protein kinase from S. coelicolor can be a good candidate for potent anti-tumor agent. The presence of three representative isotypes of the PKC super family in this organism helps us to understand the mechanism of PKC from evolutionary perspective.

Comparative analysis of antibody responses to BNT162b2, ChAdOx1, and CoronaVac vaccines in the Albanian population over the pandemic years 2021 to 2022

  • Genc Sulcebe;Margarita Kurti-Prifti;Erkena Shyti;Jonida Dashi-Pasholli;Fabian Cenko;Alban Ylli
    • Clinical and Experimental Vaccine Research
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    • 제13권1호
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    • pp.63-67
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    • 2024
  • This repeated cross-sectional study with two independent sample populations compared the antibody response to severe acute respiratory syndrome coronavirus 2 vaccines in Albania in July-August 2021 and 2022. In 2021, it found higher anti-spike-1 seropositivity and antibody levels in fully vaccinated individuals, especially with BNT162b2 and ChAdOx1 and to a lesser degree with CoronaVac. By 2022, all single-dose recipients showed high antibody responses, suggesting natural infection-enhanced immunity. The study indicates a significant evolution in the antibody response to different coronavirus disease 2019 vaccines and suggests that a single vaccine dose, coupled with natural infection, might suffice to maintain adequate immunity levels in an endemic scenario.

A Study on Design of Anti-Sway Controller for ATC using Two Degree of Freedom PID Control

  • Sohn, Dong-Seop;Lee, Jin-Woo;Lee, Young-Jin;Lee, Kwon-Soon
    • 제어로봇시스템학회:학술대회논문집
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    • 제어로봇시스템학회 2003년도 ICCAS
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    • pp.1327-1332
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    • 2003
  • In this paper, an ATC(Automated Transfer Crane) control system is required rapid transportation to get highest productivity with low cost. Therefore, the container paths should be built in terms of the least time and least sway when container is transferred from the initial coordinate to the finial coordinate. So we applied the best-first search method for forming the container path, and calculated the anti-collision path for avoiding collision in its movement to the finial coordinate. And we constructed the neural network two degree of freedom PID (TDOFPID) controller to control the precise navigation. For simulation, we constructed the container profiles so that we analyzed the state of formed path and the performance of TDOFPID controller to the formatted path. Then we compared the performance of ES-tuned PID controller with our proposed controller in terms of trolley position, anti-sway, path change, disturbance, and the load of containers. The computer simulation results show that the proposed controller has better the other on the various conditions.

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Different Way of LMP/TAP/MHC Gene Clustering in Vertebrates,. Viviparity and Anti-tumor Immunity Failure

  • Bubanovic, Ivan;Najman, Stevo
    • Animal cells and systems
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    • 제9권1호
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    • pp.1-7
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    • 2005
  • Class I and class II MHC genes have been identified in most of the jawed vertebrate taxa. In all investigated bony fish species, unlike mammals, the classical class I and class II MHC genes are not linked and even are found on different chromosomes. Linking and clustering of the class I and class II MHC genes is not the only phenomenon clearly detected in the evolution of immune system from cartilaginous to mammals. In all non-mammalian classes the LMP/TAP genes are highly conserved within class I genes region, while these genes are conserved within class II genes region only in mammals. Today we know that LMP/TAP genes in mammals have a crucial role in peptide processing for presentation within class I molecules, as well as in anti-tumor immunity. For these reasons, differences in clustering of LMP/TAP/MHC genes can be responsible for the differences in mechanisms and efficacy of anti-tumor immunity in non-mammalian vertebrates compared to same mechanisms in mammals. Also, the differences in cytokine network and anti-tumor antigens presentation within classes of vertebrates can be explained by toe peculiarity of LMP/TAP/MHC gene clustering.

Optimal Design of Piezoelectric Cantilever Fan by Three-Dimensional Finite Element Analysis

  • Kim Byoung-Jai;Rho Jong-Seok;Jung Hyung-Kyo
    • KIEE International Transaction on Electrical Machinery and Energy Conversion Systems
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    • 제5B권1호
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    • pp.90-94
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    • 2005
  • As the structure of the piezoelectric bimorph cantilever becomes increasingly more complicated, a more accurate and efficient analysis of piezoelectric media is needed. In this paper, the piezoelectric transducer is analyzed by using the three-dimensional finite element method. The validity of the three-dimensional finite element routine is confirmed by comparing the experimental result. The resonance characteristics, such as resonance frequency and anti-resonance frequency, of the piezoelectric cantilever are calculated by the experimentally verified three dimensional finite element method. Subsequently, the characteristics, such as mechanical displacement and impedance, are calculated at the resonance frequency. Besides, to design the piezoelectric bimorph cantilever shape that maximizes displacement at the tip, the ES (Evolution Strategy) algorithm is applied. Finally, optimal design for the fan of the piezoelectric cantilever is fulfilled to obtain maximum displacement at the tip. From these results, the application potentiality of the piezoelectric bimorph cantilever fan is identified.

Star-Gas Misalignment in Galaxies: II. Origins Found from the Horizon-AGN Simulation

  • Khim, Donghyeon J.;Yi, Sukyoung K.
    • 천문학회보
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    • 제46권1호
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    • pp.29.1-29.1
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    • 2021
  • There have been many studies aiming to reveal the origins of the star-gas misalignment found in galaxies, but there still is a lack of understanding of the contribution from each formation channel candidate. We explore the properties, origins, and lifetimes of the star-gas misalignment using Horizon-AGN, a large-volume cosmological simulation. First, the misalignment fraction shows a strong anti-correlation with the kinematic morphology (V/sigma) and the cold gas fraction of the galaxy. This result is consistent with the result of integral field spectroscopy observations. Second, we have identified four main formation channels of misalignment and quantified their level of contribution: mergers (35%), interaction with nearby galaxies (23%), interaction with dense environments or their central galaxies (21%), and secular evolution including smooth accretion from neighboring filaments (21%). Third, the decay timescale of the misalignment is strongly linked with the kinematic morphology of the galaxy: early-type galaxies (2.28 Gyr) tend to have a longer misalignment lifetime than LTGs (0.49 Gyr). We also found that the morphology and cold gas fraction are both and independently anti-correlated with the misalignment lifetime.

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근대 디자인의 전환기적 시점에 있어서 장식론의 전개과정에 관한 연구 (A Study on the Development of Ornamental Theory Design in Transitional Age)

  • 조영배;김홍기;윤도근
    • 한국실내디자인학회논문집
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    • 제2호
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    • pp.40-45
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    • 1994
  • This thesis is to research the change in attitude regarding the architectura ornament. One of the key dogmas within Modern Movement of art and design was anti-ornamentalism. The modernist had revolted against ornament and believed that the greatness of the modern age might lay in its inability to produce a new form of ornament. Architectural ornament has been passed through an process of evolution in a decadent stage. In this context, the purpose of this study is to identify historical meaning of architectural ornament in the age of transition toward Modernism.

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LOW-RESOLUTION SPECTROSCOPIC STUDIES OF GLOBULAR CLUSTERS WITH MULTIPLE POPULATIONS

  • LIM, DONGWOOK;HAN, SANG-IL;ROH, DONG-GOO;LEE, YOUNG-WOOK
    • 천문학논총
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    • 제30권2호
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    • pp.255-259
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    • 2015
  • Recent narrow-band Ca photometry discovered two distinct red giant branch (RGB) populations in some massive globular clusters (GCs) including M22, NGC 1851, and NGC 288. In order to investigate the differences in light/heavy elements abundances between the two subpopulations, we have performed low-resolution spectroscopy for stars on the two RGBs in these GCs. We find a significant difference (more than $4{\sigma}$) in calcium abundance from the spectroscopic HK' index for both M22 and NGC 1851. We also find a more than $8{\sigma}$ difference in CN band strength between the Ca-strong and Ca-weak subpopulations. For NGC 288, however, we detect the presence of a large difference only in the CN strength. The calcium abundances of the two subpopulations in this GC are identical within errors. We also find interesting differences in CN-CH relations among these GCs. While CN and CH indices are correlated in M22, they show an anti-correlation in NGC 288. However, NGC 1851 shows no difference in CH between two groups of stars having different CN strengths. The CN bimodality in these GCs could be explained by pollution from intermediate-mass asymptotic giant branch stars and/or fast-rotating massive stars. For the presence or absence of calcium bimodality and the differences in CN-CH relations, we suggest these would be best explained by how strongly type II supernovae enrichment has contributed to the chemical evolutions of these GCs.

하드웨어 기반 Anti-DDoS 대응 장비 고속 패킷 필터링을 위한 Hi-DPI 알고리즘 연구 (Development Hi-DPI Algorithm for High Speed Packet Filtering of Anti-DDoS based on HW)

  • 김점구
    • 융합보안논문지
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    • 제17권2호
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    • pp.41-51
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    • 2017
  • 인터넷 활용 범위의 폭발적인 증가는 점차적으로 네트워크 속도와 용량을 초고속화 하고 대용량화로 빠르게 진화해 가고 있다. 이에 따라 스위치 라우터 등 네트워크 장비들은 하드웨어에 기반 한 빠른 기술 진화로 대처를 하고 있으나 초연결사회에 가장 기본적이고 필수적인 네트워크 보안시스템의 기술 진화는 수만 가지의 보안 이슈와 시그니처(signature)에 대해서 수시 변경과 갱신을 필요로 하기 때문에 소프트웨어에 기반 한 기술적인 한계를 극복하기가 쉽지 않다. 본 논문은 이와 같은 DDoS 대응 장비를 설치 운영할 때의 패킷 필터링 속도 저하 문제점을 개선하고자 FPGA(Field Programmable Gate Array)의 하드웨어적인 특성과 병렬처리 특성을 최대한 반영한 DPI 알고리즘인 Hi-DPI를 제안하고 실용성을 검증하고자 한다.