• The Bulletin of The Korean Astronomical Society
• /
• v.43 no.1
• /
• pp.46.1-46.1
• /
• 2018

In order to investigate the origin of multiple stellar populations in the halo and bulge of the Milky Way, we have constructed chemical evolution models for the low-mass proto-Galactic subsystems such as globular clusters. Unlike previous studies, we assume that supernova blast waves undergo blowout without expelling the pre-enriched gas, while relatively slow winds of massive stars, together with the winds and ejecta from low and intermediate mass asymptotic-giant-branch stars, are all locally retained in these less massive systems. We find that the observed Na-O anti-correlations in metal-poor GCs can be reproduced when multiple episodes of starbursts are allowed to continue in these subsystems. A specific form of star formation history with decreasing time intervals between the stellar generations, however, is required to obtain this result, which is in good agreement with the parameters obtained from our stellar evolution models for the horizontal-branch. The "mass budget problem" is also much alleviated by our models without ad-hoc assumptions on star formation efficiency and initial mass function. We also applied these models to investigate the origin of super helium-rich red clump stars in the metal-rich bulge as recently suggested by Lee et al. (2015). We find that chemical enrichments by the winds of massive stars can naturally reproduce the required helium enhancement (dY/dZ = 6) for the second-generation stars. Disruption of proto-globular clusters in a hierarchical merging paradigm would have provided helium enhanced stars to the bulge field.

• Genomics & Informatics
• /
• v.6 no.1
• /
• pp.44-49
• /
• 2008

Protein kinase C (PKC) is a family of kinases involved in the transduction of cellular signals that promote lipid hydrolysis. PKC plays a pivotal role in mediating cellular responses to extracellular stimuli involved in proliferation, differentiation and apoptosis. Comparative analysis of the PKC-${\alpha},{\beta},{\varepsilon}$ isozymes of 200 recently sequenced microbial genomes was carried out using variety of bioinformatics tools. Diversity and evolution of PKC was determined by sequence alignment. The ser/thr protein kinases of Streptomyces coelicolor A3 (2), is the only bacteria to show sequence alignment score greater than 30% with all the three PKC isotypes in the sequence alignment. S.coelicolor is the subject of our interest because it is notable for the production of pharmaceutically useful compounds including anti-tumor agents, immunosupressants and over two-thirds of all natural antibiotics currently available. The comparative analysis of three human isotypes of PKC and Serine/threonine protein kinase of S.coelicolor was carried out and possible mechanism of action of PKC was derived. Our analysis indicates that Serine/ threonine protein kinase from S. coelicolor can be a good candidate for potent anti-tumor agent. The presence of three representative isotypes of the PKC super family in this organism helps us to understand the mechanism of PKC from evolutionary perspective.

• 제어로봇시스템학회:학술대회논문집
• /
• 2003.10a
• /
• pp.1327-1332
• /
• 2003

In this paper, an ATC(Automated Transfer Crane) control system is required rapid transportation to get highest productivity with low cost. Therefore, the container paths should be built in terms of the least time and least sway when container is transferred from the initial coordinate to the finial coordinate. So we applied the best-first search method for forming the container path, and calculated the anti-collision path for avoiding collision in its movement to the finial coordinate. And we constructed the neural network two degree of freedom PID (TDOFPID) controller to control the precise navigation. For simulation, we constructed the container profiles so that we analyzed the state of formed path and the performance of TDOFPID controller to the formatted path. Then we compared the performance of ES-tuned PID controller with our proposed controller in terms of trolley position, anti-sway, path change, disturbance, and the load of containers. The computer simulation results show that the proposed controller has better the other on the various conditions.

• Animal cells and systems
• /
• v.9 no.1
• /
• pp.1-7
• /
• 2005

Class I and class II MHC genes have been identified in most of the jawed vertebrate taxa. In all investigated bony fish species, unlike mammals, the classical class I and class II MHC genes are not linked and even are found on different chromosomes. Linking and clustering of the class I and class II MHC genes is not the only phenomenon clearly detected in the evolution of immune system from cartilaginous to mammals. In all non-mammalian classes the LMP/TAP genes are highly conserved within class I genes region, while these genes are conserved within class II genes region only in mammals. Today we know that LMP/TAP genes in mammals have a crucial role in peptide processing for presentation within class I molecules, as well as in anti-tumor immunity. For these reasons, differences in clustering of LMP/TAP/MHC genes can be responsible for the differences in mechanisms and efficacy of anti-tumor immunity in non-mammalian vertebrates compared to same mechanisms in mammals. Also, the differences in cytokine network and anti-tumor antigens presentation within classes of vertebrates can be explained by toe peculiarity of LMP/TAP/MHC gene clustering.

• KIEE International Transaction on Electrical Machinery and Energy Conversion Systems
• /
• v.5B no.1
• /
• pp.90-94
• /
• 2005

As the structure of the piezoelectric bimorph cantilever becomes increasingly more complicated, a more accurate and efficient analysis of piezoelectric media is needed. In this paper, the piezoelectric transducer is analyzed by using the three-dimensional finite element method. The validity of the three-dimensional finite element routine is confirmed by comparing the experimental result. The resonance characteristics, such as resonance frequency and anti-resonance frequency, of the piezoelectric cantilever are calculated by the experimentally verified three dimensional finite element method. Subsequently, the characteristics, such as mechanical displacement and impedance, are calculated at the resonance frequency. Besides, to design the piezoelectric bimorph cantilever shape that maximizes displacement at the tip, the ES (Evolution Strategy) algorithm is applied. Finally, optimal design for the fan of the piezoelectric cantilever is fulfilled to obtain maximum displacement at the tip. From these results, the application potentiality of the piezoelectric bimorph cantilever fan is identified.

• The Bulletin of The Korean Astronomical Society
• /
• v.46 no.1
• /
• pp.29.1-29.1
• /
• 2021

There have been many studies aiming to reveal the origins of the star-gas misalignment found in galaxies, but there still is a lack of understanding of the contribution from each formation channel candidate. We explore the properties, origins, and lifetimes of the star-gas misalignment using Horizon-AGN, a large-volume cosmological simulation. First, the misalignment fraction shows a strong anti-correlation with the kinematic morphology (V/sigma) and the cold gas fraction of the galaxy. This result is consistent with the result of integral field spectroscopy observations. Second, we have identified four main formation channels of misalignment and quantified their level of contribution: mergers (35%), interaction with nearby galaxies (23%), interaction with dense environments or their central galaxies (21%), and secular evolution including smooth accretion from neighboring filaments (21%). Third, the decay timescale of the misalignment is strongly linked with the kinematic morphology of the galaxy: early-type galaxies (2.28 Gyr) tend to have a longer misalignment lifetime than LTGs (0.49 Gyr). We also found that the morphology and cold gas fraction are both and independently anti-correlated with the misalignment lifetime.

• Korean Institute of Interior Design Journal
• /
• no.2
• /
• pp.40-45
• /
• 1994

This thesis is to research the change in attitude regarding the architectura ornament. One of the key dogmas within Modern Movement of art and design was anti-ornamentalism. The modernist had revolted against ornament and believed that the greatness of the modern age might lay in its inability to produce a new form of ornament. Architectural ornament has been passed through an process of evolution in a decadent stage. In this context, the purpose of this study is to identify historical meaning of architectural ornament in the age of transition toward Modernism.

• Publications of The Korean Astronomical Society
• /
• v.30 no.2
• /
• pp.255-259
• /
• 2015

Recent narrow-band Ca photometry discovered two distinct red giant branch (RGB) populations in some massive globular clusters (GCs) including M22, NGC 1851, and NGC 288. In order to investigate the differences in light/heavy elements abundances between the two subpopulations, we have performed low-resolution spectroscopy for stars on the two RGBs in these GCs. We find a significant difference (more than $4{\sigma}$) in calcium abundance from the spectroscopic HK' index for both M22 and NGC 1851. We also find a more than $8{\sigma}$ difference in CN band strength between the Ca-strong and Ca-weak subpopulations. For NGC 288, however, we detect the presence of a large difference only in the CN strength. The calcium abundances of the two subpopulations in this GC are identical within errors. We also find interesting differences in CN-CH relations among these GCs. While CN and CH indices are correlated in M22, they show an anti-correlation in NGC 288. However, NGC 1851 shows no difference in CH between two groups of stars having different CN strengths. The CN bimodality in these GCs could be explained by pollution from intermediate-mass asymptotic giant branch stars and/or fast-rotating massive stars. For the presence or absence of calcium bimodality and the differences in CN-CH relations, we suggest these would be best explained by how strongly type II supernovae enrichment has contributed to the chemical evolutions of these GCs.

• Convergence Security Journal
• /
• v.17 no.2
• /
• pp.41-51
• /
• 2017

The explosive increase in the range of Internet usage gradually makes the speed and capacity of network high-speed, rapidly evolving it into mass storage. Accordingly, network equipment such as switch and router are coping with it through hardware-based rapid technological evolution, but as the technological development of the most basic and essential network security system in the hyper-connected society requires frequent alterations and updates about the security issues and signatures of tens of thousands, so it is not easy to overcome the technical limitations based on the software. In this paper, to improve problems in installing and operating such anti-DDoS devices, we propose a Hi-DPI algorithm best reflecting the hardware characteristics and parallel processing characteristics of FPGA (Field Programmable Gate Array), and would verify the practicality.

• BMB Reports
• /
• v.40 no.4
• /
• pp.459-466
• /
• 2007

The cDNA sequence of the Japanese flounder (Paralychthys olivaceus) IgD has been previously reported (GenBank accession no. AB052658) and this was followed by the detection of IgD mRNA expression in some flounder organ tissues. However, it has not been determined whether the flounder IgD gene is virtually expressed into IgD protein. To characterize the flounder immunoglobulins utilized in elucidating the mechanism, evolution and diversity of the flounder immune system, antibodies specific to IgD and IgM were necessary. In the present study, partial flounder recombinant IgD (rIgD), IgM (rIgM) and the conserved regions of IgD and IgM (rCIg) were produced by cloning the cDNA sequence using isotype specific primers which were designed to produce unique fragments of IgD and IgM specific amino acid sequences. The production of recombinant Igs was ascertained by SDS-gel electrophoresis and immunoblot analysis using anti-T7$\cdot}$Taq antibody. The produced recombinant Igs were purified using affinity columns, and used as immunogens. Antibodies specific to the isotype of flounder Igs were generated by immunizing rabbits with rfIgs and the antibodies produced were identified by enzyme-linked immunosorbent assay (ELISA) and immunoblotting. Specificities of the generated antibodies were evaluated by testing cross-reactivity between recombinant IgM and IgD. By ELISA, rabbit antibodies against the rfIgD fragment (anti-rfIgD) failed to recognize any kind of flounder serum Igs, whereas respective antibodies against rfCIg (anti-rfCIg) and rfIgM fragments (anti-rfIgM) reacted with serum Igs. Likewise, in immunoblot assays, though anti-rfIgD did not, both anti-rfCIg and anti-rfIgM bound with the ~85 kd flounder IgM heavy chain. By flow cytometry analysis, anti-rfCIg, anti-rfIgD and anti-rfIgM reacted with 6%, 3% and 6.5% of cells, respectively, suggesting that flounder IgD is not secreted in serum but expressed on flounder B-like cell surfaces as in mammals. Antibodies produced against recombinant flounder Igs could be used to develop sandwich assay systems for detecting flounder Igs and for further investigating the flounder immune system.