• 제목/요약/키워드: annular membrane

검색결과 19건 처리시간 0.019초

Free Vibration Analysis of Solid and Annular Circular Membranes with Continuously Varying Density Using The Differential Transformation Method

  • Shin, Young-Jae;Yun, Jong-Hak;Jaun, Su-Ju;You, Young-chan
    • 한국소음진동공학회:학술대회논문집
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    • 한국소음진동공학회 2003년도 추계학술대회논문집
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    • pp.988-993
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    • 2003
  • This paper presents the application of the technique of differential transformation of free vibration of membrane. Numerical calculations are carried out and compared with previously published results. The results obtained by the present method agree very well with those reported in the previous works. The present analysis shows the usefulness and validity of differential transformation in solving a solid and annular circular membranes problem of the responses of the free vibration.

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AN INVERSE PROBLEM OF THE THREE-DIMENSIONAL WAVE EQUATION FOR A GENERAL ANNULAR VIBRATING MEMBRANE WITH PIECEWISE SMOOTH BOUNDARY CONDITIONS

  • Zayed, E.M.E.
    • Journal of applied mathematics & informatics
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    • 제12권1_2호
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    • pp.81-105
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    • 2003
  • This paper deals with the very interesting problem about the influence of piecewise smooth boundary conditions on the distribution of the eigenvalues of the negative Laplacian in R$^3$. The asymptotic expansion of the trace of the wave operator (equation omitted) for small |t| and i=√-1, where (equation omitted) are the eigenvalues of the negative Laplacian (equation omitted) in the (x$^1$, x$^2$, x$^3$)-space, is studied for an annular vibrating membrane $\Omega$ in R$^3$together with its smooth inner boundary surface S$_1$and its smooth outer boundary surface S$_2$. In the present paper, a finite number of Dirichlet, Neumann and Robin boundary conditions on the piecewise smooth components (equation omitted)(i = 1,...,m) of S$_1$and on the piecewise smooth components (equation omitted)(i = m +1,...,n) of S$_2$such that S$_1$= (equation omitted) and S$_2$= (equation omitted) are considered. The basic problem is to extract information on the geometry of the annular vibrating membrane $\Omega$ from complete knowledge of its eigenvalues by analysing the asymptotic expansions of the spectral function (equation omitted) for small |t|.

The Effect of Lidocaine.HCl on the Fluidity of Native and Model Membrane Lipid Bilayers

  • Park, Jun-Seop;Jung, Tae-Sang;Noh, Yang-Ho;Kim, Woo-Sung;Park, Won-Ick;Kim, Young-Soo;Chung, In-Kyo;Sohn, Uy Dong;Bae, Soo-Kyung;Bae, Moon-Kyoung;Jang, Hye-Ock;Yun, Il
    • The Korean Journal of Physiology and Pharmacology
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    • 제16권6호
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    • pp.413-422
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    • 2012
  • The purpose of this study is to investigated the mechanism of pharmacological action of local anesthetic and provide the basic information about the development of new effective local anesthetics. Fluorescent probe techniques were used to evaluate the effect of lidocaine HCl on the physical properties (transbilayer asymmetric lateral and rotational mobility, annular lipid fluidity and protein distribution) of synaptosomal plasma membrane vesicles (SPMV) isolated from bovine cerebral cortex, and liposomes of total lipids (SPMVTL) and phospholipids (SPMVPL) extracted from the SPMV. An experimental procedure was used based on selective quenching of 1,3-di(1-pyrenyl)propane (Py-3-Py) and 1,6-diphenyl-1,3,5-hexatriene (DPH) by trinitrophenyl groups, and radiationless energy transfer from the tryptophans of membrane proteins to Py-3-Py. Lidocaine HCl increased the bulk lateral and rotational mobility of neuronal and model membrane lipid bilayes, and had a greater fluidizing effect on the inner monolayer than the outer monolayer. Lidocaine HCl increased annular lipid fluidity in SPMV lipid bilayers. It also caused membrane proteins to cluster. The most important finding of this study is that there is far greater increase in annular lipid fluidity than that in lateral and rotational mobilities by lidocaine HCl. Lidocaine HCl alters the stereo or dynamics of the proteins in the lipid bilayers by combining with lipids, especially with the annular lipids. In conclusion, the present data suggest that lidocaine, in addition to its direct interaction with proteins, concurrently interacts with membrane lipids, fluidizing the membrane, and thus inducing conformational changes of proteins known to be intimately associated with membrane lipid.

Effects of Chlorpromazine·HCl on the Structural Parameters of Bovine Brain Membranes

  • Jang, Hye-Ock;Jeong, Dong-Keun;Ahn, Shin-Ho;Yoon, Chang-Dae;Jeong, Soo-Cheol;Jin, Seong-Deok;Yun, Il
    • BMB Reports
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    • 제37권5호
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    • pp.603-611
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    • 2004
  • Fluorescence probes located in different membrane regions were used to evaluate the effects of chlorpromazine HCl on structural parameters (transbilayer lateral mobility, annular lipid fluidity, protein distribution, and lipid bilayer thickness) of synaptosomal plasma membrane vesicles (SPMVs) isolated from bovine cerebral cortex. The experimental procedure was based on the selective quenching of 1,3-di(1-pyrenyl)propane (Py-3-Py) by trinitrophenyl groups, radiationless energy transfer from the tryptophan of membrane proteins to Py-3-Py, and energy transfer from Py-3-Py monomers to 1-anilinonaphthalene-8-sulfonic acid (ANS). In this study, chlorpromazine HCl decreased the lateral mobility of Py-3-Py in a concentration dependent-manner, showed a greater ordering effect on the inner monolayer than on the outer monolayer, decreased annular lipid fluidity in a dose dependent-manner, and contracted the membrane lipid bilayer. Furthermore, the drug was found to have a clustering effect on membrane proteins.

The Effect of Dibucaine.HCl on the Physical Properties of Neuronal Membranes

  • Jang, Hye-Ock;Hyun, Cheol-Ho;Yoon, Jin-Hyeok;Kang, Yong-Gyu;Park, Sung-Min;Park, Young-Sik;Park, Jun-Seop;Ok, Jin-Seok;Lee, Dong-Hun;Bae, Moon-Kyung;Yun, Il
    • Journal of Photoscience
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    • 제12권2호
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    • pp.67-73
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    • 2005
  • Fluorescent probe techniques were used to evaluate the effect of dibucaine.HCl on the physical properties (transbilayer asymmetric lateral mobility, annular lipid fluidity and protein distribution) of synaptosomal plasma membrane vesicles (SPMV) isolated from bovine cerebral cortex. An experimental procedure was used based on selective quenching of 1,3-di(l-pyrenyl)propane (Py-3-Py) by trinitrophenyl groups, and radiationless energy transfer from the tryptophans of membrane proteins to Py-3-Py. Dibucaine.HCl increased the bulk lateral mobility, and annular lipid fluidity in SPMV lipid bilayers, and had a greater fluidizing effect on the inner monolayer than the outer monolayer. The magnitude of increasing effect on annular lipid fluidity in SPMV lipid bilayer induced by dibucaine.HCl was significantly far greater than magnitude of increasing effect of the drug on the lateral mobility of bulk SPMV lipid bilayer. It also caused membrane proteins to cluster. These effects of dibucaine.HCl on neuronal membranes may be responsible for some, though not all, of the local anesthetic actions of dibucaine.HCl.

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Free vibration of circular and annular membranes with varying density by the method of discrete singular convolution

  • Ersoy, Hakan;Ozpolat, Lutfiye;Civalek, Omer
    • Structural Engineering and Mechanics
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    • 제32권5호
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    • pp.621-634
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    • 2009
  • A numerical method is developed to investigate the effects of some geometric parameters and density variation on frequency characteristics of the circular and annular membranes with varying density. The discrete singular convolution method based on regularized Shannon's delta kernel is applied to obtain the frequency parameter. The obtained results have been compared with the analytical and numerical results of other researchers, which showed well agreement.

Effects of Dopamine.HCI on Structural Parameters of Bovine Brain Membranes

  • Bae, Moon-Kyoung;Huh, Min-Hoi;Lee, Seung-Woo;Kang, Hyun-Gu;Pyun, Jae-Ho;Kwak, Myeong-Hee;Jang, Hye-Ock;Yun, Il
    • Archives of Pharmacal Research
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    • 제27권6호
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    • pp.653-661
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    • 2004
  • Fluorescence probes located in different membrane regions were used to evaluate the effect of dopamine$.$HCI on the structural parameters (transbilayer lateral mobility, annular lipid fluidity, protein distribution, and thickness of the lipid bilayer) of synaptosomal plasma membrane vesicles (SPMV), which were obtained from the bovine cerebral cortex. An experimental procedure was used based on selective quenching of 1,3-di(1-pyrenyl)propane (Py-3-Py) by trinitrophenyl groups, and radiationless energy transfer from the tryptophan of membrane pro-teins to Py-3-Py and energy transfer from Py-3-Py monomers to 1-anilinonaphthalene-8-sulfonic acid (ANS) was also utilized. Dopamine$.$HCI increased both the bulk lateral mobility and annular lipid fluidity, and it had a greater fluidizing effect on the inner monolayer than on the outer monolayer. Furthermore, the drug had a clustering effect on membrane proteins.

The Effect of Ethanol on the Physical Properties of Neuronal Membranes

  • Bae, Moon-Kyoung;Jeong, Dong-Keun;Park, No-Soo;Lee, Cheol-Ho;Cho, Bong-Hye;Jang, Hye-Ock;Yun, Il
    • Molecules and Cells
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    • 제19권3호
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    • pp.356-364
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    • 2005
  • Intramolecular excimer formation of 1,3-di(1-pyrenyl) propane(Py-3-Py) and fluorescence polarization of 1,6-diphenyl-1,3,5-hexatriene (DPH) were used to evaluate the effect of ethanol on the rate and range of lateral and rotational mobilities of bulk bilayer structures of synaptosomal plasma membrane vesicles (SPMVs) from the bovine cerebral cortex. Ethanol increased the excimer to monomer fluorescence intensity ratio (I'/I) of Py-3-Py in the SPMVs. Selective quenching of both DPH and Py-3-Py by trinitrophenyl groups was used to examine the range of transbilayer asymmetric rotational mobility and the rate and range of transbilayer asymmetric lateral mobility of SPMVs. Ethanol increased the rotational and lateral mobility of the outer monolayer more than of the inner one. Thus ethanol has a selective fluidizing effect within the transbilayer domains of the SPMVs. Radiationless energy transfer from the tryptophans of membrane proteins to Py-3-Py was used to examine both the effect of ethanol on annular lipid fluidity and protein distribution in the SPMVs. Ethanol increased annular lipid fluidity and also caused membrane proteins to cluster. These effects on neuronal membranes may be responsible for some, though not all, of the general anesthetic actions of ethanol.

Selective Fluidization of Synaptosomal Plasma Membrane Vesicles by 17β-Estradiol

  • Lee, Sae A;Park, Yong Jin;Jang, Il Ho;Kang, Jung Sook
    • 대한의생명과학회지
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    • 제23권1호
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    • pp.17-24
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    • 2017
  • Estrogens are effective neuroprotectants in vivo and in vitro. To obtain a better insight into the molecular mechanisms of action of neuroprotection by $17{\beta}-estradiol$ (E2), we examined the differential effects of E2 on the fluidity of synaptosomal plasma membrane vesicles (SPMV) isolated from rat cerebral cortex. Intramolecular excimerization of 1,3-di(1-pyrenyl)-propane (Py-3-Py) was used to investigate the effects of E2 on the bulk and annular lateral diffusion of the SPMV. In addition, we examined the effects of E2 on the rotational diffusion of individual leaflet of SPMV exploiting selective quenching of outer monolayer 1,6-diphenyl-1,3,5-hexatriene (DPH) fluorescence by trinitrophenyl groups. The $F{\ddot{o}}rster$ distance $R_0$ value for the tryptophan-Py-3-Py donor-acceptor pair was $26.9{\AA}$. E2 increased the lateral mobility of both bulk and annular lipids in SPMV in a dose-dependent manner, but a larger effect on bulk lipids was observed. Although E2 decreased the anisotropy of DPH in SPMV, E2 had a greater fluidizing effect on the outer leaflet compared to the inner leaflet. These results suggest that E2 selectively fluidizes the more fluid regions within SPMV. It is highly probable that E2 mostly fluidizes the bulk lipids, away from either annular lipids or lipid rafts, in the outer leaflet of SPMV. This selective fluidization may be one of the nongenomic mechanisms of neuroprotection by E2.

PZT membrane Piezoelectric Traveling Wave Motor

  • xin, Shen-De;an, Zhang-Bao;Lu jinan-guo;qing, Yang-Gen;yuan, Wang-Wei
    • 한국진공학회지
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    • 제6권S1호
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    • pp.89-95
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    • 1997
  • A new type of piexoelectric membrane traveling wave motor has been designed and forbricated. The small motor is composed by the stator which is the combination of annular/circular membrane and metal elastic base using as the common electrode at some time and the rotor which is placed on the metal elastic body. Thus the motor structure is simple and easy to fabricate. The material of a piezoelectric membrane is fabricated by sol-gel method or wear-down method. A piezoelectric traveling wave motor has been fabricated with the stator diameter 8mm The total thickness of the stator is 350$\mu$m. Under the alternative excitation voltage 10-12V the revolving speed of the rotor is more than 100RPM.

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