• 제목/요약/키워드: animal study

검색결과 17,692건 처리시간 0.052초

Effects of dietary supplementation of polysaccharide from Agaricus blazei Murr on productive performance, egg quality, blood metabolites, intestinal morphology and microbiota of Korean quail

  • Liang Hong;Zheng Ma;Xueyi Jing;Hua Yang;Jifei Ma;Lei Pu;Jianbin Zhang
    • Animal Bioscience
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    • 제37권8호
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    • pp.1452-1462
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    • 2024
  • Objective: This study aimed to investigate the effects of dietary supplementation with Agaricus blazei polysaccharide (ABP) at varying concentrations on the performance, egg quality, blood biochemistry, intestinal morphology, and microflora of quail. Methods: The study involved a total of 2,700 Korean quails, which were randomly divided into three groups. The measured variables encompassed productive performance, egg parameters, carcass parameters, serum metabolites, immune response parameters, antioxidative properties, and gut microbiome. Results: The addition of ABP did not have a significant effect on average daily feed intake. However, it was found to increase the average daily egg weight and egg production rate, reduce the feed-egg ratio. There were no significant impacts on egg quality measures such as egg shape index, egg yolk index and color, egg yolk and protein content. However, ABP supplementation significantly increased the Hough unit (p<0.01) and decreased the rate of unqualified eggs (p<0.01). Regarding serum parameters, the inclusion led to an increase in total protein concentration (p<0.05) and a reduction in low-density lipoprotein cholesterol (p<0.05). There were no significant effects observed on immune indicators such as immunoglobulin A (IgA) and IgM. ABP supplementation increased the levels of serum antioxidant indicators, including glutathione peroxidase, total superoxide dismutase (p<0.05), and total antioxidant capacity colorimeter (p<0.05). Furthermore, ABP supplementation significantly elevated the intramuscular fatty acid content in quail meat. Additionally, ABP supplementation demonstrated a significant improvement in the diversity of gut microbiota and induced alterations in the composition of the gut microbiota. Conclusion: The findings of this study indicate that dietary supplementation of ABP enhanced production performance and antioxidant capacity while increasing the levels of polyunsaturated fatty acids in quail muscle.

Genome wide association study of fatty acid composition in Duroc swine

  • Viterbo, Vanessa S.;Lopez, Bryan Irvine M.;Kang, Hyunsung;Kim, Hoonseop;Song, Choul-won;Seo, Kang Seok
    • Asian-Australasian Journal of Animal Sciences
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    • 제31권8호
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    • pp.1127-1133
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    • 2018
  • Objective: Genome wide association study was conducted to identify and validate candidate genes associated with fatty acid composition of pork. Methods: A total of 480 purebreed Duroc pigs were genotyped using IlluminaPorcine60k bead chips while the association test was implemented following genome-wide rapid association using Mixed Model and Regression-Genomic Control (GRAMMAR-GC) approach. Results: A total of 25, 29, and 16 single nucleotide polymorphisms (SNPs) were significantly associated with stearic (18:0), oleic (18:1) and saturated fatty acids (SFA), respectively. Genome wide significant variants were located on the same region of swine chromosome 14 (SSC14) that spanned from 120 to 124 Mb. Top SNP ALGA008191 was located at 5 kb near the stearoyl-CoA desaturase (SCD) gene. This gene is directly involved in desaturation of stearic acid into oleic acid. General relationship of significant SNPs showed high linkage disequilibrium thus genome-wide signals was attributed to SCD gene. However, understanding the role of other genes like elongation of very long chain fatty acids-3 (ELOVL3) located on this chromosomal segment might help in further understanding of metabolism and biosynthesis of fatty acids. Conclusion: Overall, this study provides evidence that validates SCD gene as strong candidate gene associated with fatty acid composition in Duroc pigs. Moreover, this study confirms significant SNPs near ELOVL3 gene.

A comparison of metabolomic changes in type-1 diabetic C57BL/6N mice originating from different sources

  • Lee, Seunghyun;Kwak, Jae-Hwan;Kim, Sou Hyun;Yun, Jieun;Cho, Joon-Yong;Kim, Kilsoo;Hwang, Daeyeon;Jung, Young-Suk
    • Laboraroty Animal Research
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    • 제34권4호
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    • pp.232-238
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    • 2018
  • Animal models have been used to elucidate the pathophysiology of varying diseases and to provide insight into potential targets for therapeutic intervention. Although alternatives to animal testing have been proposed to help overcome potential drawbacks related to animal experiments and avoid ethical issues, their use remains vital for the testing of new drug candidates and to identify the most effective strategies for therapeutic intervention. Particularly, the study of metabolic diseases requires the use of animal models to monitor whole-body physiology. In line with this, the National Institute of Food and Drug Safety Evaluation (NIFDS) in Korea has established their own animal strains to help evaluate both efficacy and safety during new drug development. The objective of this study was to characterize the response of C57BL/6NKorl mice from the NIFDS compared with that of other mice originating from the USA and Japan in a chemical-induced diabetic condition. Multiple low-dose treatments with streptozotocin were used to generate a type-1 diabetic animal model which is closely linked to the known clinical pathology of this disease. There were no significantly different responses observed between the varying streptozotocin-induced type-1 diabetic models tested in this study. When comparing control and diabetic mice, increases in liver weight and disturbances in serum amino acids levels of diabetic mice were most remarkable. Although the relationship between type-1 diabetes and BCAA has not been elucidated in this study, the results, which reveal a characteristic increase in diabetic mice of all origins are considered worthy of further study.

A Taxonomic Review of the Genus Lycocerus (Cantharidae: Coleoptera) in Korea, with a Newly Recorded Species, Lycocerus striatus

  • Kang, Tae Hwa;Kim, Tae Woo;Seo, Hong Yul
    • Animal Systematics, Evolution and Diversity
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    • 제33권3호
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    • pp.203-210
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    • 2017
  • A taxonomic review of the Korean Lycocerus (Cantharidae, Coleoptera) was presented. Through this study, total of four species were found from Korea including a species new to Korea, Lycocerus striatus. We newly provided a key to the Korean Lycocerus species and the distributional map on each species in this study.

회화 복원용 교의 적용이 종이 특성에 미치는 영향 (Influence of Animal Glues Application for Painting Restoration on Paper Characteristics)

  • 박미선;김형진
    • 펄프종이기술
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    • 제47권4호
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    • pp.127-135
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    • 2015
  • Artists have been used animal glues for a long time as binding and sizing materials of paintings in many countries including Korea. Since animal glues as a binding material lose their own adhesive strength by aging, pigment particles or pigment layers are easily detached from painting surface. Restaurators prefer to use animal glues for consolidation of pigment particles or pigment layers because artists use animal glues as a binder for their painting works. It is widely known that animal glues have different characteristics such as viscosity, stability on water etc. But there are still a few requirements to consider their stabilities for the restoration of paintings. Therefore, this study was aimed to evaluate of stability and efficiency of animal glue applications. The efficiency of animal glue application was decreased with increasing the concentration of animal glue solution. This result means the simple tendency, but does not representative data for other animal glues made from same raw materials. In most cases, the surface and mechanical characteristics of animal glues are dependent on some factors, like viscosity and concentration of animal glue solution.

Comparison of the Quality of the Chicken Breasts from Organically and Conventionally Reared Chickens

  • Kim, Dong-Hun;Cho, Soo-Hyun;Kim, Jin-Hyoung;Seong, Pil-Nam;Lee, Jong-Moon;Jo, Cheor-Un;Lim, Dong-Gyun
    • 한국축산식품학회지
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    • 제29권4호
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    • pp.409-414
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    • 2009
  • In this study, the quality of chicken breasts from organically reared chickens was compared with that of chicken breasts from conventionally reared chickens. Broilers were raised in an indoor pen with conventional and organic production system, respectively. The diet formulation for the organically reared chickens and the production density were in accordance with the guidelines for organic chicken products. Twenty birds from each group were slaughtered and their breasts were obtained for analysis. The organic chicken breasts had a higher cooking loss, and waterholding capacity, and a lower shear force (p<0.05) compared to the conventional chicken breasts. The organic chicken breasts also showed higher $a^{\ast}$ and $b^{\ast}$ values and myoglobin contents compared with the conventional chicken breasts (p<0.05). In the fatty-acid analysis, the organic chicken breasts resulted in higher polyunsaturated fatty acid (PUFA) and unsaturated fatty acid contents, and a higher PUFA-saturated fatty acid ratio.

The Possibility of TBC1D21 as a Candidate Gene for Teat Numbers in Pigs

  • Jin, S.;Lee, J.B.;Kang, K.;Yoo, C.K.;Kim, B.M.;Park, H.B.;Lim, H.T.;Cho, I.C.;Maharani, D.;Lee, J.H.
    • Asian-Australasian Journal of Animal Sciences
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    • 제26권10호
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    • pp.1374-1378
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    • 2013
  • Based on a quantitative traits locus (QTL) study using a $F_2$ intercross between Landrace and Korean native pigs, a significant QTL affecting teat numbers in SSC7 was identified. The strong positional candidate gene, TBC1D21, was selected due to its biological function for epithelial mesenchymal cell development. Sequence analysis revealed six single nucleotide polymorphisms (SNPs) in the TBC1D21 gene. Among these, two SNP markers, one silent mutation (SNP01) for g.13,050A>G and one missense mutation (SNP04) for c.829A>T (S277C), were genotyped and they showed significant associations with teat number traits (p value = 6.38E-05 for SNP01 and p value = 1.06E-07 for SNP04 with total teat numbers). Further functional validation of these SNPs could give valuable information for understanding the teat number variation in pigs.

유기축산을 위한 농장동물복지의 과제와 평가 (A Task and Valuation on Farm Animal Welfare for Organic Livestock)

  • 유덕기
    • 한국유기농업학회지
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    • 제15권3호
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    • pp.237-256
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    • 2007
  • Organic farming is promoted financially in the Republic of Korea since 2000. The, entire segment shows a very dynamic development since that time. Now, a large bouquet of measures are offered which target the promotion of organic farming. This article presents a study about the Task and Valuation on farm animal welfare for Organic Livestock. Among the supports are grants for organically managed livestock farm, investment incentives, the promotion of organic livestock husbandry, the promotion of producer co-operatives, the development of farm animal right index for animal health and animal welfare, publicity measures and measures to raise consumer awareness as well as the support of training, extension and research in the field organic livestock farming. Government must ensure that necessary incentives and sanctions are in place to maintain and improve animal welfare standards and they must be delivered appropriately. Animal welfare legislation provides essential protection for economy, environment, animals and society as a whole, must be properly observed.

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심리학 및 행동생물학적 연구에서 동물 로봇의 활용과 전망 (Perspectives on the Use of Robots in Etho-experimental Approaches to Animal Behavior)

  • 최준식
    • 로봇학회논문지
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    • 제17권1호
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    • pp.86-92
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    • 2022
  • Utilization of small robots in psychology and biology provides a new breakthrough in understanding the neurobiological mechanisms of various animal behavior. The expansion of robot use in animal research is partly due to increased availability of economically plausible mobile robots and also due to the current shift in animal research toward more ecologically valid experiments. Ground-breaking experimental findings are expected when the behavioral variables are manipulated in more natural situations. In addition, the results from laboratory could be generalized more easily with added ecological validity. The current paper attempts to review a wide range of applications of animal robots used to study animal behavior and to highlight major advantages and limitations. In particular, this review focuses more on the psychological impact of animal robots than engineering details about their structure and operation. Finally, this review will provide some practical considerations when employing robots in animal experiments.