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Monocrotophos induced inhibition of the activities of testis and accessory reproductive organs in male mice

  • Patill, Saraswati B;Malashetty, Vijaykumar B
    • Advances in Traditional Medicine
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    • 제7권3호
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    • pp.304-310
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    • 2007
  • Monocrotophos was administered orally to adult male albino mice at dose level of 3.0 mg/kg body weight/day/mice for 50 days. The treatment has found to affect spermatogenesis as well as the endocrine functions of the testis as indicated by gravimetric, histopathological and biochemical changes. The treatment has caused degenerative changes in the seminiferous tubules and Leydig cells of the testis and regression of the epididymis, seminal vesicle, vas deferens, prostate, Cowper's gland and levator ani. Similarly, cauda epididymal sperm count and sperm motility have shown significant reduction. There was a significant reduction in the protein, glycogen, sialic acid, acid and alkaline phosphatase and increase in cholesterol in the testis of monocrotophos treated mice compared with the control. The causative factors for these changes due to monocrotophos administration were discussed.

The Cytotoxic Action of New Ag-Porphyrin as a Potential Chemotherapeutic Agent

  • Nelli, Babayan;Artak, Tovmasyan;Ani, Gevorkyan;Gennadi, Gasparyan;Rouben, Aroutiounian
    • 환경생물
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    • 제26권2호
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    • pp.115-120
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    • 2008
  • Earlier we have described new water-soluble Ag- and Zn-derivatives of tetrachloride meso-tetra (4-N-oxiethylpyridyl) porphyrin (TOEtPyP) as potential anticancer drugs. In this work the effect of one of these metal porphyrins, TOEtPyP Ag, on the cell population kinetics was studied in vitro using morphological and biochemical techniques. The results suggested that TOEtPyP Ag action consisted in the simultaneous suppression of the cell growth and activation of the cell death. About 40% of the cells were shown to die via apoptotic pathway. So, the porphyrin studied may be attributed to inducers of both necrotic and apoptotic processes. The results obtained support our previous assertion that TOEtPyP Ag may be considered as a potential chemotherapeutic agent.

h-index, h-type Indices, and the Role of Corrected Quality Ratio

  • Tahira, Muzammil;Alias, Rose Alinda;Bakri, Arayti;Shabri, Ani
    • Journal of Information Science Theory and Practice
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    • 제2권4호
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    • pp.20-30
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    • 2014
  • This study examines the foremost concerns related to most noted research performance index. The most popular and widely acceptable h-index underestimates the highly visible scientist, the middle order group, due to citation distribution issues. The study addresses this issue and uses 'Corrected Quality Ratio' (CQ) to check the implicit underpinnings as evident in h-index. CQ helps to incorporate the aspects of a good research performance indicator. This simple revision performs more intimately and logically to gauge the broader research impact for all groups and highly visible scientists with less statistical error.

The Basis Number of the Lexicographic Product of Different Ladders with Paths and Cycles

  • Alzoubi, Maref Yousef Mohammad;Al-Ta'Ani, Reem Rafe' Ayed
    • Kyungpook Mathematical Journal
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    • 제48권2호
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    • pp.303-315
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    • 2008
  • In [8] M. Y. Alzoubi and M. M. Jaradat studied the basis number of the composition of paths and cycles with Ladders, Circular ladders and M$\"{o}$bius ladders. Namely, they proved that the basis number of these graphs is 4 except possibly for some cases in each of them. Since the lexicographic product is noncommutative, in this paper we investigate the basis number of the lexicographic product of the different kinds of ladders with paths and cycles. In fact, we prove that the basis number of almost all of these graphs is 4.

2주형 판형교의 최적설계 (Optimization of Two Plate Girders Bridge)

  • 김건희;유선미;조선규
    • 한국철도학회:학술대회논문집
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    • 한국철도학회 2002년도 추계학술대회 논문집(I)
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    • pp.690-695
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    • 2002
  • Two plate girders bridge has an advantage for execution of works and quality control because of its simplicity of super-structure caused by decreasing in amount of members and also is distinguished as aesthetic bridge type. Recently this has been adopted for structure of highway as well railway and introduced into domestic. In order to plan or design two plate girders bridge more rationably, it is necessary to comprehend its structural behavior as well as to consider the critical resign factors. Thus, in this study the formulation of optimum design for two plate girders bridge is proposed and the critical resign variables ani restraints are considered and founded by caring out optimum design. The objective function of optimization is formulated as a minimum cost design problem. And the thickness and length of I-shaped section are decided as resign variables. The design constraints are formulated based on Design Criteria for Railroad(Bridges). By comparing the optimum results with those of the conventional resign, the effectiveness of proposed optimum design formulation is investigated. From the results, the way to do optimum design of two plate girders bridge is suggested.

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Human resource planning for authorized inspection activity

  • Lee, Seung-hee;Field, Robert Murray
    • Nuclear Engineering and Technology
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    • 제51권2호
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    • pp.618-625
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    • 2019
  • When newcomer countries consider a nuclear power programme, it is recognized that the most important organizations are the Nuclear Energy Programme Implementing Organization (NEPIO), the regulator, and an operating organization. Concerning the number of construction delays these days, one of the essential organizations is an Authorized Inspection Agency (AIA). According to World Nuclear Industry Status Report, all of the reactors under construction in eight out of the thirteen countries have experienced delays. Globally, the Flamanville 3 project and Sanmen Unit 1 are 6.5 years and 5 years late respectively. One of the major reasons of delay is due to inappropriate manufacturing and inspection on safety class components. The recommendations are made to develop such an organization: (i) find existing inspection organizations in relevant industries, (ii) contract with expatriates who have experience on nuclear inspection, (iii) develop a legislative framework to authorize the inspection organization with enforcement, (iv) include a contract clause in the BIS for developing the AIA, (v) hold training programmes from vendor country, (vi) during manufacturing and construction, domestic AIA shall be involved.

PRIVATE DEVELOPERS' UNDERSTANDING ON THE IMPLEMENTATION OF STRATEGIC PARTNERING IN THE MALAYSIAN CONSTRUCTION INDUSTRY

  • Faridah Muhamad Halil;Mohammad Fadhil Mohammad;Rohana Mahbub;Ani Saifuza Shukor
    • 국제학술발표논문집
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    • The 4th International Conference on Construction Engineering and Project Management Organized by the University of New South Wales
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    • pp.542-549
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    • 2011
  • This research will attempt to reveal that private developers in the Malaysian construction industry have been practicing strategic partnering in their organizations. While the investigation was conducted using quantitative and qualitative approaches, this paper will only reveal results obtained from the questionnaire survey. Results from the questionnaire survey indicate that private developers in the Malaysian construction industry had implemented strategic partnering in their organizations. The elements of the partnering process, which are partnering formation, partnering application and partnering completion or reactivation were tested. The results show that all the elements of the partnering process have been exercised in their projects. Thus it can be surmised that strategic partnering has been practiced by private developers in the Malaysian construction industry.

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Draft Genome of an AmpC-β-Lactamase Producing Serratia marcescens Isolate from Fresh farm Tomatoes in South Africa

  • Maike Claussen;Stefan Schmidt
    • 한국미생물·생명공학회지
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    • 제51권3호
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    • pp.309-313
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    • 2023
  • Here we report essential features of the draft genome of an AmpC-β-lactamase-producing bacterial isolate obtained from farm tomatoes in South Africa. The isolate designated strain Tom1 featured a genome of 4950426 bp with a G+C% of 59.83. It was identified as Serratia marcescens by ribosomal multilocus sequence typing (rMLST), digital DNA-DNA hybridization (dDDH), average nucleotide identity (ANI), and phylogenetic analysis using reference genomes. Its genome encoded an AmpC-β-lactamase (blaSST-1), an efflux pump providing tetracycline resistance (tet(41)), and an aminoglycoside acetyltransferase (aac(6')-Ic). Additionally, genes encoding proteins involved in prodigiosin biosynthesis and associated with adherence, biofilm formation, virulence, and pathogenicity were detected.

Stem cell therapy for dogs with immune-mediated hemolytic anemia

  • Yeonmi Lee;Eunju Kang;Junguk Ju
    • 한국동물생명공학회지
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    • 제39권1호
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    • pp.58-61
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    • 2024
  • Three different dogs who had immune-mediated hemolytic anemia (IMHA) were treated for more than two weeks with blood transfusion in an animal clinic. Despite this treatment and hospitalization, there was no clinical improvement in clinical signs as well as complete blood cell count (CBC) including hematocrit (HCT) and C-reactive protein (CRP). All cases were then injected two or three times with allogeneic stem cells through an intravenous route for treatment. Upon administrating stem cells to the IMHA dogs, clinical conditions and the indexes of HCT and CRP were clinically improved within or close to normal ranges.

육자원(肉資源) 개발(開發)을 위한 한국재래산양(韓國在來山羊)의 이용(利用)에 관(關)한 연구(硏究) (Studies on the Utilization of Korean Native Goat for Meat Production)

  • 라광연;권순기;김종우
    • 농업과학연구
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    • 제4권1호
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    • pp.75-83
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    • 1977
  • 1. 재래산양(在來山羊)의 사료섭취(飼料攝取) 경향(傾向)은 주간(晝間)이 야간(夜間)보다 많으며 중량(重量)에 대한 생초섭취량(生草攝取量)은 9~15%였다. 2. 하기(夏期)에는 사료섭취량(飼料攝取量)이 감소(減少)되며 체중(體重)도 감소(減少)되었다. 3. 생초(生草)나 건초(乾草)의 품질(品質)이 저질화(低質化)되면 농후사료(濃厚飼料) 섭취량(攝取量)이 증가(增加)된다. 4. 강류급여구(糠類給與區)나 배합강료급여구(配合糠料給與區)에 있어서 조사료(粗飼料)의 섭취량(攝取量)은 동일(同一)하였다. 5. 사양표준(飼養標準)에 의(依)해서 재래산양(在來山羊)을 사육(飼育)하는 것이 T. D. N이나 D. C. P. M. E의 요구량(要求量)을 감소(減少)시킬 수 있다. 6. 자양(仔羊)의 주폐사원인(主弊死原因)이 되는 내부기생충(內部寄生蟲)은 위충(胃蟲), 장결절충(腸結節蟲), 간질(肝蛭), 코크시듐이며 주기적(週期的) 예방(豫防)이 필요(必要)하다. 7. 격목구(擊牧區) 농원사료구(農原飼料區), 배합사료구(配合飼料區)에서 육성(育成)된 한국재래산양(韓國在來山羊)의 도체시험(屠體試驗) 결과(結果) 격목구(擊牧區)는 35.10%의 도체율(屠體率)과 29.92%의 정육율(精肉率)을 얻었고 농원사료구(濃原飼料區)는 42.17%의 도체율(屠體率)과 30.25%의 정육율(精肉率) 증가(增加)를 가져왔고, 배합사료구(配合飼料區)는 44.56%와 33.99%의 가장 좋은 산육성(産肉性)을 나타냈다. 8. 각구별(各區別) 도체성분(屠體成分)의 일반조성(一般組成) 분석결과(分析結果)는 농원사료(濃原飼料)의 급여(給與)에 따라서 지방함량(脂肪含量)은 증가(增加)하고 수분(水分) 및 조회분(粗灰分)등은 감소(減少)하는 현상(現象)을 나타냈다. 9. 이취주성분(異臭主成分)인 체지방(體脂肪)이 정육(精肉)에서 4 %정도 채취(採取)되었다. 10. Sausage, 통조림 제조(製造)에 사용(使用)된 향신료(香辛料)중 Clover Pepper, group가 가장 풍미개선(風味改善)에 효과적(效果的)이였다. 11. 제조기술적면(製造技術的面)에서 볼 때 가공용(加工用) 육자원(肉資源)으로써 사용(使用)이 가능(可能)하다고 인정(認定)되였다.

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