• 기본간호학회지
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• 제13권3호
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• pp.447-456
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• 2006

Purpose: This study was done to examine symptom experiences and related factors in angina patients. Method: The participants were 92 patients admitted to C university hospital between October and December 2004. The tools used were a questionnaire on symptom experience related to angina developed by Gensini(Coronary Angiographic Gensini Score). Global Assessment of Recent Stress Scale and a tool measuring performance of health behavior. Results: The mean score for symptom experience was relatively low (M=27.65, SD=18.44) as was the score for coronary severity (Gensini score) was 16.30 point (SD=18.04). The mean score for perceived stress was moderate (M=30.16, SD=12.26). Compliance was relatively good in these patients with angina (M=61.55, SD=7.60). Analysis of the correlation of symptom experience showed a statistically significant positive relationship with perceived stress (r=.410, p=.000). There was significant negative relationship (r=-.251, p=.016) between symptom experience and compliance. In the regression analysis, symptom experience was found to be significantly influenced by stress ($R^2$=.168, p=.000), age ($R^2$=.057, p=.002), and economic status ($R^2$=.061, p=.007). These variables explained 26.2% of the variance in symptom experience. Conclusion: The results of this study provide evidence that symptoms of angina can present not only as chest pain itself but also with fatigue, shortness of breath, and sleep disturbance as the most common symptoms.

• Journal of Chest Surgery
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• 제28권9호
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• pp.876-880
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• 1995

The optimal surgical approach to the patients with coronary artery disease combined with carotid artery stenosis is controversial. We report two cases of successful surgical management of the patients with combined obstructive coronary and carotid artery disease. The first case was a 69-year-old female who had unstable angina pectoris and a past medical history of left carotid endarterectomy. She was revealed to have triple vessel coronary disease and nearly total occlusion of right internal carotid artery. She was undergone staged right carotid endarterectomy 10 days before coronary bypass surgery. The second case, a 54-year-old male with a past medical history of left hemiparesis and dysarthria, was admitted due to unstable angina pectoris. He was revealed to have triple-vessel coronary disease and more than 90% stenosis of left internal carotid artery and 50% stenosis of right internal carotid artery. In the latter case, a combined coronary bypass surgery and left carotid endarterectomy was done. In both cases, postoperative neurologic complications were not observed.

• Bulletin of the Korean Chemical Society
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• 제32권7호
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• pp.2274-2278
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• 2011

Verapamil is a calcium channel blocker and is classified as a class IV anti-arrhythmic agent. It is used in the control of supra ventricular tachyarrhythmias, and in the management of classical and variant angina pectoris. It is also used in the treatment of hypertension and used as an important therapeutic agent for angina pectoris, ischemic heart disease, hypertension and hypertrophic cardiomyopathy. Verapamil commonly co-administered with NSAIDs (non-steroidal anti-inflammatory drugs) i.e. diclofenac sodium, flurbiprofen, Ibuprofen, mefanamic acid and meloxicam. A simple and rapid RP-HPLC method for simultaneous determination and quantification of verapamil and NSAIDs was developed and validated. The mobile phase constituted of acetonitrile: water (55:45) whose pH was adjusted at 2.7 and pumped at a flow rate of 2.0 mL $min^{-1}$ at 230 nm. The proposed method is simple, precise, accurate, low cost and least time consuming for the simultaneous determination of verapamil and NSAIDs which can be effectively applied for the analysis of human serum.

• Journal of Chest Surgery
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• 제25권11호
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• pp.1369-1375
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• 1992

During a 17-month period 32 consecutive patients underwent coronary artery bypass graft. The mean age of these patients was 45.3 years [range 39 to 71 years]. There were 18 men and 14 women. Preoperatively 11 patients had stable angina pectoris and 12 patients of unstable angina pectoris. 28% [9 patients] had of myocardial infarction history. The patterns of disease were single vessel involvement [4 casis], double vessel involvement [11 cases], triple vessel involvement [12 caese] and 5 cases of left main coronary artery disease. Thirty-seven percent [12/32] were in New York Heart Association class IV. Myocardial revascularization was performed under emergency conditions in 3 patients. We performed 13 case of double anastomosis, 12 case of triple anastomosis and 4 case of 4 anstomosis [mean 2.59 anastomosis per patient]. The left internal mammary artery was used in 68.7%. 90% of the patients receieved two or more grafts. Complications occurred in 8 patients [25%]. All patients were followed up for a mean of 8.6 months [2 to 17 months]. There was no hospital and late death. Postoperatively 87% were in New York Heart Association class I or II and 96% of the patient were free from angina.

• Journal of Chest Surgery
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• 제39권4호
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• pp.320-322
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• 2006

60세 남자 환자가 호흡곤란 및 협심증을 의심케 하는 흉통을 주소로 내원하였다. 시행한 비침습성 검사상 좌심방 후면에 종양이 발견되었다. 심폐기하에서 종양제거술을 시행하였다. 종양은 좌심방에서 기시하였으며 다른 장기로의 침범은 없었다. 조직검사상 부분 괴사를 동반한 성숙 지방 세포였으며 지방종으로 확진되었다. 이에 심낭 내 좌심방에서 기원한 드문 심장 지방종을 발표하는 바이다.

• 한국치위생학회지
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• 제18권5호
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• pp.653-664
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• 2018

Objectives: The purpose of this study was to examine the association between two major oral diseases and cardiovascular diseases. Methods: Data from the 6th Korean National Health and Nutrition Examination Survey (2013-2015) were used. The study included 12,754 adults, aged ${\geq}19years$, who participated in the questionnaire survey of health related to hypertension, stroke, myocardial infarction, and angina pectoris as well as completed blood tests, anthropometry, and oral examination. Statistical analyses included complex sample frequency, complex sample general linear, complex sample cross-tabulation, and complex sample logistic regression analyses. Results: With respect to the number of Decayed-Missing-Filled-Teeth(DMFT ), patients with hypertension (DMFT 8.05), stroke (DMFT 8.66), and angina pectoris (DMFT 8.24) showed a DMFT score of >2, compared with those who did not have these diseases (p<0.05). Patients with hypertension, stroke, myocardial infarction, and angina pectoris presented an approximately 2.7, 3.5, 4, and 3 times higher incidence of periodontal diseases, respectively, than those who did not (p<0.05). Based on the analysis of the relationship between the number of DMFT and cardiovascular diseases, patients with cardiovascular diseases had a risk of 1.033 higher DMFT than those who did not (p<0.05). As per the analysis of the relationship between periodontal diseases and cardiovascular diseases, patients with cardiovascular diseases had a 2.969 higher risk of periodontaldiseasesthanthosewithout them (p<0.05). Conclusions: Two major oral diseases were found to be associated with cardiovascular diseases. Therefore, to prevent these major oral diseases in patients with cardiovascular diseases, oral hygiene management must be actively performed.

• 성인간호학회지
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• 제21권5호
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• pp.477-488
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• 2009

Purpose: This study was conducted to identify the clinical characteristics and risk factors on the occurrence of variant angina, and to examine the predicting factors on the vascular endothelial dysfunction of the patients with variant angina. Methods: A total of 134 patients diagnosed with variant angina were recruited from 2006 to 2008. The degrees of endothelial dysfunction were measured and recorded by the researcher using the values of flow-mediated vasodilation of their brachial arteries and Nitroglycerine-mediated dilation. Subjects' demographic data and risk factors were gathered after obtaining informed consent, and their electronic medical records were reviewed to collect laboratory data. Results: The mean age was $54.2{\pm}9.6$ years and 52% was male patients. More than 50% of the male patients were cigarette smokers and had hypercholesterolemia. 84% of the male patients and 70% of the female patients had more than one risk factor of cardiovascular disease. A stepwise multiple regression analysis showed that smoking and hypercholesterolemia predicted the decrease of flow-mediated vasodilation (Adjusted $R^2$ = .204, p < .001). Conclusion: Tailored educational interventions for smoking cessation and cholesterol management are needed to prevent recurrence of angina attack for patients with variant angina and to prevent cardiovascular disease for middle-aged workers.

• 대한간호학회지
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• 제42권2호
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• pp.190-198
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• 2012

Purpose: The aim of this study was to evaluate the effects of a smoking cessation education on endothelial function and carboxyhemoglobin levels in smokers with variant angina. Methods: A nonequivalent control group pretest-posttest design was used. Participants were 60 male smokers with variant angina admitted to one hospital: the control group (30) between September and December, 2009, and the experimental group (30) between February and May, 2010. Endothelial function, as defined by flow-mediated vasodilation (FMD) of the brachial artery, and serum carboxyhemoglobin (COHb) were determined at baseline and at 3 months after the initiation of education in both groups. Results: Three months after the program, smoking cessation was successful in 22 of the 30 smokers in the experimental group, but only in 4 of 30 smokers in the control group ($p$<.001). After the education, the experimental group showed a significant increase in FMD, and a significant decreased in serum COHb compared with the control group. Conclusion: The findings indicate that this smoking cessation education program is effective for hospitalized smokers with variant angina.

• 사상체질의학회지
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• 제14권2호
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• pp.125-131
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• 2002

An ischemic heart disease(IHD) is a anemic state of heart caused by disproportion between heart's demand and supply of oxygen. A patient who has this IHD feels serious chest pain called angina pectoris. In a keen condition it leads to a necrosis of heart muscles, known as myocardial infarction. In an ischemic heart disease the ECG waves gives us useful information of patients' heart. And CK(creatine kinase) in serum and Troponin T are the principal factors in diagnosis of IHD. In this study, the IHD patient classified by Sasang Constitutional Medicine had a notable medical effects. The symptoms of patient are disappeared and waves of ECG is closed to normal. The result of CK in serum is also recovered. So we report the healing process and results of this patient in this study.

• Journal of Chest Surgery
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• 제38권3호
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• pp.253-257
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• 2005

원발성 폐암의 환자에서 협심증을 동반하고 있는 경우 그 동안 관상동맥우회술을 폐수술 전에 먼저 시행하여 교정하는 단계적인 방법이 주로 이용되었다. 그러나 최근 관상동맥우회술과 폐절제를 동시에 시행하여 단계적 수술 방법의 단점으로 지적되고 있는 두 번의 전신마취, 두 개의 수술상처, 폐 절제의 지연 등을 감소시키려는 경향이 늘고 있고, 좋은 성적을 보고하고 있다. 본원에서도 국내 최초로 폐절제와 관상동맥우회술을 동시에 시행하여 수술 후 양호한 경과를 보이면서 현재까지 추적 관찰하는 중에 암과 협심증의 재발이 없음을 관찰하였기에 보고하는 바이다.