• Korean Journal of Pharmacognosy
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• v.35 no.1 s.136
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• pp.52-61
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• 2004

Inhibitory activities of 264 methanol extracts, which were prepared from different parts of 210 kinds of wild and medicinal plants, against human thrombin were evaluated. Based on the anti-coagulation activity determined by thrombin time and activated partial thromboplastin time, the 14 extracts were screened. The fibrinolytic activity, heat stability and inhibition of other proteolytic digestive enzymes, such as pepsin, papain, trypsin and chymotrypsin, of the 14 extracts were further determined, and Ginko biloba (herba), Ephedra sinica (radix), Reynoutria elliptica (herba), Amomum tsao-ko Crevost (fructus), and Magnolia officinalis Rehd. et Wils (bark) were finally selected as possible plant sources for anti-thrombosis agent. These results suggested that medicinal and wild plants could be the potential source of thrombin inhibitor.

• Proceedings of the Plant Resources Society of Korea Conference
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• 2022.09a
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• pp.93-93
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• 2022

Hovenia dulcis, one of the traditional medicinal plants, is currently being used as a functional ingredient for the development of health functional foods that protects the liver from alcohol damage in Korea. A variety of pharmacological effects of Hovenia dulcis have been reported so far, but studies on immune-enhancing activity are insufficient. Thus, in this study, we report that Hovenia dulcis branches (HDB) induce the activation of macrophages. HDB increased the production of immunostimulatory factors and phagocytosis in RAW264.7 cells. TLR4 inhibition blocked HDB-mediated production of immunostimulatory factors. In addition, the JNK inhibition reduced the HDB-mediated production of immunostimulatory factors, and the HDB-mediated JNK activation was blocked by the TLR4 inhibition. HDB increased the level of LC3-II and p62/SQSTM1. TLR4 inhibition blocked HDB-mediated increase in the level of LC3-II and p62/SQSTM1. These findings indicate that HDB may induce TLR4/JNK-dependent macrophage activation and TLR4-dependent macrophage autophagy.

• PNF and Movement
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• v.22 no.1
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• pp.23-30
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• 2024

Purpose: Ankle instability is a common issue in both daily activities and sports, often leading to recurrent injuries. Elastic taping is a non-pharmacological intervention used to improve ankle stability. This study aimed to investigate the immediate effects of elastic taping on ankle stability, center of pressure (COP) movement, and foot pressure distribution. Methods: A single-group pre-posttest design was employed, with 30 participants included in the study. Plantar pressure and COP parameters were measured before and after the application of elastic taping. Taping was administered in three distinct patterns to enhance ankle stability. Results: Immediate effects of elastic taping were evident in COP parameters. Following taping application, there was a significant decrease in COP total displacement, COP area, and COP velocity. However, no significant changes were observed in plantar pressure parameters. Conclusion: The application of elastic taping in this study demonstrated immediate effects on ankle stability and COP parameters, indicating its potential as a viable intervention for improving balance. Further research with larger sample sizes and long-term follow-up is needed to elucidate the sustained effects of elastic taping on ankle stability.

• Physical Therapy Rehabilitation Science
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• v.5 no.4
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• pp.198-204
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• 2016

Objective: The purpose of this study was to examine the effects of hip joint exercise using an elastic band on dynamic balance, agility, and flexibility in healthy subjects. Design: Randomized controlled trial. Methods: Thirty-five subjects (between 19 and 23 years) were randomly allocated to two groups: hip flexion exercise (HFE) group (n=17) and the hip abduction exercise (HAE) group (n=18). The HFE group participated in flexion exercise of the hip joint using an elastic band for 50 minutes a day, three days a week for four weeks, while the HAE group participated in abduction exercises of the hip joint using an elastic band for the same period. Dynamic balance was measured using the timed up and go (TUG) test, agility was measured with the standing long jump, and flexibility was measured using the Schober's test (5 cm, 10 cm). Results: The HFE group showed significant differences in the TUG test, standing long jump, and the Schober's test (10 cm) after training (p<0.05). The HAE group showed significant differences in the TUG test, standing long jump and the Schober's test (5 cm, 10 cm) after training (p<0.05). However, there was no significant difference between the HFE group and the HAE group. Conclusions: Flexion and abduction exercises of the hip joint using and elastic band increased dynamic balance, agility, and flexibility in healthy subjects. Additional research on hip joint exercises using an elastic band for improving dynamic balance, agility and flexibility are necessary.

• Journal of Life Science
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• v.20 no.9
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• pp.1378-1384
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• 2010

The present study aimed to investigate the effect of heavy metal contamination in the aquatic environment on the fishes (Opsariichthys bidens, Cyprinus carpio, Hemiculter eigenmanni and Culter brevicauda) inhabiting Andong and Imha reservoirs by comparing and analyzing the heavy metal contents accumulated in their tissues. Heavy metal contents were shown to be higher in the Andong reservoir than in the Imha reservoir. Accumulated heavy metals, Cr, Cu and Pb, were detected in tissues and bone tissues, but Cd was also found in the kidneys. Zn content was the highest among accumulated metals, whereas Cu content was the lowest in all tissues from the fishes in the Andong and Imha reservoirs. However, the amount of Cr in the tissues showed a twofold higher level in the Andong reservoir than that in Imha reservoir. The heavy metal contents of fish inhabiting the Andong reservoir were detected to be higher than those in the Imha reservoir. We also proposed that heavy metal contamination in water and its inhabiting fish is attributed to various heavy metals derived from water and sediments in the water environment of the Andong reservoir.

• Microbiology and Biotechnology Letters
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• v.35 no.3
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• pp.231-237
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• 2007

To support the fermentational superiority of Korean nuruks and maintain the various domestic nuruks, the optimal nuruk production of Andong-Soju, which was designated as an intangible cultural asset of Gyungsangbukdo province from 1987, was investigated. Different thickness of nuruks ($2.2{\sim}5.5\;cm$) were manufactured based on traditional Andong-Soju nuruk method, while the size of round form of nuruk was set to 23 cm. During the 3 weeks maturation, changes of water content, weight, pH, brix, the amount of reducing sugar, sac-charifying activity, viable cell and major microorganisms were determined, Also, ethanol fermentation abilities of the manufactured nuruks were evaluated using 20% glucose medium or 16% starch medium, respectively. Our results indicated that the production of high quality of Andong-Soju nuruk needs $4.0{\sim}5.5\;cm$ thickness and 3 weeks maturation without extraneous yeast addition. These results would be applied to production of homogeneous, and high quality of Andong-Soju nuruk.

• 한국약용작물학회:학술대회논문집
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• 2007.05a
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• pp.82-83
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• 2007

• Communications for Statistical Applications and Methods
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• v.3 no.3
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• pp.253-261
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• 1996

In this paper, we derive the maximum likelihood estimator of P=P(X

• Proceedings of the Zoological Society Korea Conference
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• 1998.10b
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• pp.266.1-266
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• 1998

No Abstract, See Full Text

• Proceedings of the Korean Society for Bio-Environment Control Conference
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• 2004.03a
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• pp.176-183
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• 2004