• Proceedings of the KIEE Conference
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• 2001.07b
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• pp.1263-1265
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• 2001

This study presents accurate simulation to examine a reason rail potential rise and how to design ground connection(Cross Connection Cable, CCC) and draw up a plan of an optimal buried grounding system according to section.

• Proceedings of the Korean Information Science Society Conference
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• 2012.06d
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• pp.360-362
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• 2012

현재 안테나 자체는 Active Antenna Array 화 되어있다. 이 방법은 백홀, 기저 대역(baseband)을 통해 광케이블로 연결하여, 대표적인 WARP 와 CCC 가 있다. 안테나에서의 기저 대역을 통해 광케이블로 연결한다. 이 이유는 데이터 용량에 따라 트래픽이 증가 되었기 때문에 대용량의 데이터 전송을 위해 광케이블로 사용한 것이다. 따라서 AAA와 Cloud RAN의 주요 장점들을 제안하고 있는 주요 기업들에 대한 최근 동향을 살피고 그에 따른 주요 이슈를 나타내어 이 논문에서의 향후 연구 방향을 제안한다.

• Health Policy and Management
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• v.28 no.4
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• pp.402-410
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• 2018

Background: Monitoring appropriate medication categories can provide early warning of certain disease outbreaks. This study aimed to present a methodology for selecting and monitoring medications relevant to the surveillance of acute respiratory tract infections, such as influenza. Methods: To estimate correlations between acute febrile respiratory tract infection and some medication categories, the cross-correlation coefficient (CCC) was used and established. Two databases were used: real-time prescription trend of antivirals, anti-inflammatory drugs, antibiotics using Drug Utilization Review Program between 2012 and 2015 and physicians' number of encounters with acute febrile respiratory tract infections such as influenza outbreaks using the national level health insurance claims data. The seasonality was also evaluated using the CCC. Results: After selecting six candidate diseases that require extensive monitoring, influenza with highly specific medical treatment according to the health insurance claims data and its medications were chosen as final candidates based on a data-driven approach. Antiviral medications and influenza were significantly correlated. Conclusion: An annual correlation was observed between influenza and antiviral medications, anti-inflammatory drugs. Suitable models should be established for syndromic surveillance of influenza.

• 대한예방의학회:학술대회논문집
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• 1999.10a
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• pp.1-15
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• 1999

In a case-control study to evaluate the factors involved in the development of hepatocellular carcinoma, polymorphisms of the p53 gene were compared in 68 cases mostly infected with hepatitis C virus (HCV) and 68 controls matched for sex and age: DNA from peripheral blood leukocytes was analyzed by the polymerase chain reaction-single strand conformation polymorphism method and direct sequencing. Polymorphisms analyzed were those in exon 4 (CCC vs. CGC, Pro vs. Arg at codon 72, Al allele vs. A2 allele), intron 2 (C vs. G at nucleotide 38, Al vs. A2), intron 3 (C vs. A at nucleotide 65, Al vs. A2; absence and presence of 16 base pair repeat at nucleotides 24 to 39, Al vs. A2), intron 6 (A vs. G at nucleotide 62, Al vs. A2) and intron 7 (C and T vs. T and G at nucleotides 72 and 92, Al vs. A2). A significantly higher frequency of the allele for CCC (Pro, Al) at codon 72 of exon 4 was found in cases (39%) than in controls (26%) (p<0.05). Highly significant linkage of the polymorphisms in exon 4, intron 2, intron 3 and intron 7, and between the intron 3-16 bp duplication and polymorphism in intron 6 also was found. Matched Fair analysis showed significantly higher frequencies of certain haplotypes (1-1-1-1-2-2 or 1-1-2-1-2-1 for exon 4, intron 2, intron 3, the intron 3-16 bp duplication, intron 6 and intron 7) in cases than in controls (p=0.014, OR=2.27, 95% CI= 1.08-5.12). No preference of specific p53 polymorphisms for specific HCV genotype was detected. These findings suggest that in hepatocarcinogenesis mainly due to HCV infection, genetic factors may be involved and that genetic markers can serve as predictors of a high-risk group for hepatocarcinogenesis.

• The Sea:JOURNAL OF THE KOREAN SOCIETY OF OCEANOGRAPHY
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• v.5 no.1
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• pp.10-15
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• 2000

Goals, research direction, and operational structure of the Global Ocean Ecosystem Dynamics (GLOBEC), which is co-sponsored by the Scientific Committee on Oceanic Research (SCOR) and the Intergovemmental Oceanographic Commission (IOC), are described. Following the Joint Global Ocean Flux Study (JGOFS) activities on the lower trophic level in ecosystem during 1980s-90s, scientists have considered the responses of the mid and higher trophic levels to the environmental or climate change. The scientific steering committee of the GLOBEC published the implementation plan in 1999, and the IGBP will support the GLOBEC as one of its core projects for 10 years. The GLOBEC programme has four major components: the research foci, framework activities, regional programmes, and integrating activity. The core of GLOBEC research is the four research foci: retrospective analyses, process studies, predictive and modelling capabilities, and feedbacks. Currently, four regional programmes have been undergoing in the world ocean: Southern Ocean GLOBEC (SO-GLOBEC), Small Pelagic Fishes and Climate Changes (SPACC), Cod and Climate Change (CCC), and Climate Change and Carrying Capacity (CCCC). Also, national GLOBEC programmes were already established in 9 nations.

• Korean Journal of Pharmacognosy
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• v.35 no.4 s.139
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• pp.288-292
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• 2004

To evaluate the quality of the crude drugs using three kinds of Cinnamomum Cortex (CC), Vietnamese CC (VCC, the stem bark of Cinnamomum obtusifolium), periderm-peeled Chinese CC (PPCC, periderm-peeled stem bark of C. cassia), Chinese CC (CCC, stem bark of C. cassia) and a Cinnamomi Ramulus (CR, the twig of C. cassia), the four essential oils were prepared by steam distillation method. Cinnamaldehdye (CAN) and an unknown substance tentatively named hydroxy-cinnamaldehdye(HCNA) were detected in the four essential oils by gas chromatography-mass spectrometry, the contents of which are significantly different one another. Vietnamese CC had the highest content of HCNA whereas CR had the highest CAN content and the lowest HCNA. Vietnamese CC exhibited the greatest cytotoxic activity against the cancer cell lines, A549, HepG-2, HL-60, P-388, U-937, and KB and CR the lowest cytotoxicity. Contents of CAN and HCNA in CCC and PPCC are positioned between VCC and CR. These results suggest that measurement of HCNA and cytotoxicity may determine the quality of CC and CR.

• Journal of the Korea Society of Computer and Information
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• v.10 no.4 s.36
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• pp.123-132
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• 2005

A version control system is used in a rapidly changed environment or a program which developed in a complicated environment. And configuration thread information supporting and it's processing method has an important part in version control. Configuration thread tool such as a system model of DSEE, a view of ClearCase, a label of SourceSafe, and the package of CCC/Harvest have applied to formalized configuration rule by user and obtained a desired configuration information of the version. But it is a problem of configuration thread in supporting information that we. in this method. can't know a exactly well-defined configuration rule information and a predefined information. And these information have a demerit that can't supported the close connection along with undefined version and a meta-information. In this paper. we have modeling a system for these problems to solve and a efficiently configuration thread supported. We also proposed a mixed retrieval model included a boolean retrieval model and a vector retrieval model for support efficiently configuration thread information. We applied and designed the libraries using extended facet method.

• Journal of Korean Public Health Nursing
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• v.31 no.2
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• pp.327-340
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• 2017

Purpose: The aim of this study was to identify the barriers to promoting physical activity among obese children from low-income families using community child care (CCC) centers. Methods: This study employed an exploratory-descriptive qualitative research using focus group interviews. The participants were recruited from CCC centers, and 4 focus group interviews were conducted with 10 overweight and obese children and 14 primary caregivers. All interviews were recorded and transcribed verbatim. The data were analyzed using content analysis. Results: The barriers to promoting physical activity were classified into three areas: 1) individual, a lack of will for physical activity; 2) interpersonal, a change in communicative mean with the peer group, absence of parental monitoring due to work-family balance, and an absence of consistent rules; and 3) organizational, lack of physical activity programs and human resources, and confined space for physical activity. Conclusion: The physical activity of children in low-income families is influenced by a range of ecological barriers. These findings can be used to develop tailored intervention to prevent and manage childhood obesity in low-income children.

• Applied Biological Chemistry
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• v.33 no.3
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• pp.239-246
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• 1990

Monascus anka strains with higher pigment production were developed using UV mutation and natural selection. To obtain organic solvent soluble pigments from Monascus anka, the following culture conditions were compared : standing and shaking culture with Nishikawa's medium, and shaking culture with Lin's medium. Shaking culture in Lin's medium exhibited decrease in solvent-soluble intracellular pigments after initial increase. The decrease was accompanied by the increase in water-soluble extracellular pigments. Monascus anka preferred sucrose and ethanol among 7 carbon sources tested. Treatment of sterol biosynthesis inhibitors, $({\pm})$-miconazole and chlorocholine chloride(CCC) , directed carbon pool to the biosynthetic pathway leading to the pigments with CCC's more pronounced effect. Two dimensional TLC revealed at least 7 yellow pigments suggesting existence of hereto unreported pigment. One of the most abundant yellow pigments was isolated and found to be ankaflavin by NMR and MS analysis.

• The Korean Journal of Physiology and Pharmacology
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• v.25 no.5
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• pp.449-457
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• 2021

The sleep-wake cycle is regulated by the alternating activity of sleep- and wake-promoting neurons. The dorsal raphe nucleus (DRN) secretes 5-hydroxytryptamine (5-HT, serotonin), promoting wakefulness. Melatonin secreted from the pineal gland also promotes wakefulness in rats. Our laboratory recently demonstrated that daily changes in nitric oxide (NO) production regulates a signaling pathway involving with-no-lysine kinase (WNK), Ste20-related proline alanine rich kinase (SPAK)/oxidative stress response kinase 1 (OSR1), and cation-chloride co-transporters (CCC) in rat DRN serotonergic neurons. This study was designed to investigate the effect of melatonin on NO-regulated WNK-SPAK/OSR1-CCC signaling in wake-inducing DRN neurons to elucidate the mechanism underlying melatonin's wake-promoting actions in rats. Ex vivo treatment of DRN slices with melatonin suppressed neuronal nitric oxide synthase (nNOS) expression and increased WNK4 expression without altering WNK1, 2, or 3. Melatonin increased phosphorylation of OSR1 and the expression of sodium-potassium-chloride co-transporter 1 (NKCC1), while potassium-chloride co-transporter 2 (KCC2) remained unchanged. Melatonin increased the expression of tryptophan hydroxylase 2 (TPH2, serotonin-synthesizing enzyme). The present study suggests that melatonin may promote its wakefulness by modulating NO-regulated WNK-SPAK/OSR1-KNCC1 signaling in rat DRN serotonergic neurons.