• 대한임상약리학회:학술대회논문집
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• 2006.11a
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• pp.141-142
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• 2006

• 한국정보디스플레이학회:학술대회논문집
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• 2009.10a
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• pp.282-285
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• 2009

Nanostructured OLED light extraction films have been made via roll-to-roll coating processes. Their on-axis and integrated outcoupling efficiencies reach 2X and 1.3-1.8X, respectively. Optical performance and effects of the nanostructured film on pixel blur and image ghosting will be discussed.

• Asian-Australasian Journal of Animal Sciences
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• v.31 no.7
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• pp.1043-1061
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• 2018

Intramuscular fat (IMF) content in skeletal muscle including the longissimus dorsi muscle (LM), also known as marbling fat, is one of the most important factors determining beef quality in several countries including Korea, Japan, Australia, and the United States. Genetics and breed, management, and nutrition affect IMF deposition. Japanese Black cattle breed has the highest IMF content in the world, and Korean cattle (also called Hanwoo) the second highest. Here, we review results of research on genetic factors (breed and sex differences and heritability) that affect IMF deposition. Cattle management factors are also important for IMF deposition. Castration of bulls increases IMF deposition in most cattle breeds. The effects of several management factors, including weaning age, castration, slaughter weight and age, and environmental conditions on IMF deposition are also reviewed. Nutritional factors, including fat metabolism, digestion and absorption of feed, glucose/starch availability, and vitamin A, D, and C levels are important for IMF deposition. Manipulating IMF deposition through developmental programming via metabolic imprinting is a recently proposed nutritional method to change potential IMF deposition during the fetal and neonatal periods in rodents and domestic animals. Application of fetal nutritional programming to increase IMF deposition of progeny in later life is reviewed. The coordination of several factors affects IMF deposition. Thus, a combination of several strategies may be needed to manipulate IMF deposition, depending on the consumer's beef preference. In particular, stage-specific feeding programs with concentrate-based diets developed by Japan and Korea are described in this article.

• Safety and Health at Work
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• v.7 no.2
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• pp.111-119
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• 2016

Background: Shift work and/or sleep quality may affect health. We investigated whether shift work and sleep quality, separately and jointly, were associated with abnormal levels of triglycerides, total cholesterol (TC), and low-and high-density lipoprotein cholesterol in 360 police officers (27.5% women). Methods: Triglycerides, TC, and high-density lipoprotein were analyzed on the Abbott Architect; low-density lipoprotein was calculated. Shift work was assessed using City of Buffalo payroll work history records. Sleep quality (good, ${\leq}5$; intermediate, 6-8; poor, ${\geq}9$) was assessed using the Pittsburgh Sleep Quality Index questionnaire. A shift work + sleep quality variable was created: day plus good sleep; day plus poor sleep; afternoon/night plus good; and poor sleep quality. Mean values of lipid biomarkers were compared across categories of the exposures using analysis of variance/analysis of covariance. Results: Shift work was not significantly associated with lipids. However, as sleep quality worsened, mean levels of triglycerides and TC gradually increased but only among female officers (age- and race-adjusted p = 0.013 and 0.030, respectively). Age significantly modified the association between sleep quality and TC. Among officers ${\geq}40$ years old, those reporting poor sleep quality had a significantly higher mean level of TC ($202.9{\pm}3.7mg/dL$) compared with those reporting good sleep quality ($190.6{\pm}4.0mg/dL$) (gender- and race-adjusted p = 0.010). Female officers who worked the day shift and also reported good sleep quality had the lowest mean level of TC compared with women in the other three categories (p = 0.014). Conclusion: Sleep quality and its combined influence with shift work may play a role in the alteration of some lipid measures.

• Journal of Veterinary Science
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• v.23 no.1
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• pp.2.1-2.18
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• 2022

Background: Co-infections of the porcine reproductive and respiratory syndrome virus (PRRSV) and the Haemophilus parasuis (HPS) are severe in Chinese pigs, but the immune response genes against co-infected with 2 pathogens in the lungs have not been reported. Objectives: To understand the effect of PRRSV and/or HPS infection on the genes expression associated with lung immune function. Methods: The expression of the immune-related genes was analyzed using RNA-sequencing and bioinformatics. Differentially expressed genes (DEGs) were detected and identified by quantitative real-time polymerase chain reaction (qRT-PCR), immunohistochemistry (IHC) and western blotting assays. Results: All experimental pigs showed clinical symptoms and lung lesions. RNA-seq analysis showed that 922 DEGs in co-challenged pigs were more than in the HPS group (709 DEGs) and the PRRSV group (676 DEGs). Eleven DEGs validated by qRT-PCR were consistent with the RNA sequencing results. Eleven common Kyoto Encyclopedia of Genes and Genomes pathways related to infection and immune were found in single-infected and co-challenged pigs, including autophagy, cytokine-cytokine receptor interaction, and antigen processing and presentation, involving different DEGs. A model of immune response to infection with PRRSV and HPS was predicted among the DEGs in the co-challenged pigs. Dual oxidase 1 (DUOX1) and interleukin-21 (IL21) were detected by IHC and western blot and showed significant differences between the co-challenged pigs and the controls. Conclusions: These findings elucidated the transcriptome changes in the lungs after PRRSV and/or HPS infections, providing ideas for further study to inhibit ROS production and promote pulmonary fibrosis caused by co-challenging with PRRSV and HPS.

• Animal Bioscience
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• v.37 no.5
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• pp.952-961
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• 2024

Objective: Stocking density (SD) is an important issue in the poultry industry, which is related to the production performance, intestinal health and immune status. In the present study, the effects of SD on the metabolism and homeostasis of uric acid as well as the related functions of the liver and kidney in ducks were examined. Methods: A total of 360 healthy 56-day-old Shan-ma ducks were randomly divided into the low stocking density (n = 60, density = 5 birds/m²), medium stocking density (n = 120, density = 10 birds/m²) and high stocking density groups (HSD; n = 180, density = 15 birds/m²). Samples were collected in the 3rd, 6th, and 9th weeks of the experiment for analysis. Results: The serum levels of uric acid, lipopolysaccharide and inflammatory cytokines (interleukin-1β [IL-1β], IL-8, and tumor necrosis factor-α [TNF-α]) were increased significantly in the HSD group. Serious histopathological lesions could be seen in both the livers and kidneys in the HSD group in the 9th week. The mRNA expression levels of inflammatory cytokines (IL-8 and TNF-α) and related pathway components (toll-like receptor 4, myeloid differentiation primary response gene 88, and nuclear factor-κB) were increased significantly in both the livers and kidneys in the HSD group. The mRNA expression levels of enzymes (adenosine deaminase, xanthine oxidase, phosphoribosyl pyrophosphate amidotransferase, and phosphoribosyl pyrophosphate synthetase 1) related to the synthesis of uric acid increased significantly in the livers in the HSD group. However, the mRNA expression level of solute carrier family 2 member 9, which plays an important role in the excretion of uric acid by the kidney, was decreased significantly in the kidneys in the HSD group. Conclusion: These results indicated that a higher SD could cause tissue inflammatory lesions in the liver and kidney and subsequently affect the metabolism and homeostasis of uric acid, and is helpful for guiding decisions related to the breeding and production of ducks.

• Journal of Sasang Constitutional Medicine
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• v.24 no.4
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• pp.1-16
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• 2012

Objectives : We aimed to analyze the meanings of the energy and fluid metabolism in the Discourse on Viscera and Bowels of Donguisusebowon, and to find the clues for the explanation of the pathology and symptomatology of Taeeumin. Methods : The Discourse on Viscera and Bowels of Donguisusebowon was reviewed and examined for relevant information on the energy and fluid metabolism from the structural and the functional point of view respectively. And, based on the derived meanings of the energy and fluid metabolism, the pathology and symptomatology of Taeeumin were analyzed. Results and Conclusions : 1. The meanings of the energy and fluid metabolism can be explained by the different attributes of the energy and fluid produced from the esophagus and the small intestine, and the different function of exhaling-dispersing and inhaling-concentrating in the different tract of circulation such as Lung affiliation (esophagus, skin, ear and lung) and Liver affiliation (small intestine, flesh, nose and liver). 2. The Exterior disease of Taeeumin starts with the weakness of exhaling-dispersing function at the skin, and leads to the dysfunction of the esophagus and the lung sequently. The dysfunction of the lung aggravates that of the skin and the esophagus. 3. The Interior disease of Taeeumin begins with excess of the inhaling-concentrating functions at the flesh and the small intestine, and leads to the dysfunction of the lung, which induces the dysfunction of exhaling-concentration at the skin and esophagus. And, this disparities between exhaling-dispersing and inhaling-concentrating functions exasperate the problem at the flesh and the small intestine.

• Journal of Environmental Science International
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• v.26 no.6
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• pp.767-778
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• 2017

This research investigates the characteristics of metallic and ionic elements in $PM_{10}$ and $PM_{2.5}$ on haze day and non-haze day in Busan. $PM_{10}$ concentration on haze day and non-haze day were 85.75 and $33.52{\mu}g/m^3$, respectively, and $PM_{2.5}$ on haze day and non-haze day were 68.24 and $23.86{\mu}g/m^3$, respectively. Contribution rate of total inorganic water-soluble ion to $PM_{10}$ mass on haze day and non haze day were 58.2% and 61.5%, respectively, and contribution rate of total water-soluble ion to $PM_{2.5}$ mass on haze day and non haze day were 58.7% and 64.7%, respectively. Also, contribution rate of secondary ion to $PM_{10}$ mass on haze day and non haze day were 52.1% and 47.5%, respectively, and contribution rate of secondary ion to $PM_{2.5}$ mass on haze day and non haze day were 54.4% and 53.6%, respectively. AC (anion equivalents)/CE (cation equivalents) ratio of $PM_{10}$ mass on haze day and non haze day were 1.09 and 1.0, respectively, and AC/CE ratios of $PM_{2.5}$ mass on haze day and non haze day were 1.12 and 1.04, respectively. Also, SOR (Sulfur Oxidation Ratio) of $PM_{10}$ mass on haze day and non haze day were 0.32 and 0.17, respectively, and SOR of $PM_{2.5}$ on haze day and non haze day were 0.30 and 0.15, respectively. Lastly, NOR (Nitrogen Oxidation Ratio) of $PM_{10}$ on haze day and non haze day were 0.17 and 0.08, respectively, and NOR of $PM_{2.5}$ on haze day and non haze day were 0.13 and 0.06, respectively.

• Geomechanics and Engineering
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• v.15 no.6
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• pp.1173-1182
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• 2018

The coal wall, gob-side backfill, and gangues in goaf, constitute the support system for Gob-side entry retaining (GER) in coal mines. Reasonably allocating and utilizing their bearing capacities are key scientific and technical issues for the safety and economic benefits of the GER technology. At first, a mechanical model of GER was established and a governing equation for coordinated bearing of the coal-backfill-gangue support system was derived to reveal the coordinated bearing mechanism. Then, considering the bearing characteristics of the coal wall, gob-side backfill and gangues in goaf, their quantitative design methods were proposed, respectively. Next, taking the No. 2201 haulage roadway serving the No. 7 coal seam in Jiangjiawan Mine, China, as an example, the design calculations showed that the strains of both the coal wall and gob-side backfill were larger than their allowable strains and the rotational angle of the lateral main roof was larger than its allowable rotational angle. Finally, flexible-rigid composite supporting technology and roof cutting technology were designed and used. In situ investigations showed that the deformation and failure of surrounding rocks were well controlled and both the coal wall and gob-side backfill remained stable. Taking the coal wall, gob-side backfill and gangues in goaf as a whole system, this research takes full consideration of their bearing properties and provides a quantitative basis for design of the support system.

• 한국환경농학회:학술대회논문집
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• 2009.07a
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• pp.228-239
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• 2009

The observations on climate change show a clear increase in the temperature of the Earth's surface and the oceans, a reduction in the land snow cover, and melting of the sea ice and glaciers. The effects of climate change are likely to include more variable weather, heat waves, increased mean temperature, rains, flooding and droughts. The threat of climate change and global warming on human and animal health is now recognized as a global issue. This presentation is described an overview of the latest scientific knowledge on the impact of climate change on zoonotic diseases. Climate strongly affects agriculture and livestock production and influences animal diseases, vectors and pathogens, and their habitat. Global warming are likely to change the temporal and geographical distribution of infectious diseases, including those that are vector-borne such as West Nile fever, Rift Valley fever, Japanese encephalitis, bluetongue, malaria and visceral leishmaniasis, and other diarrheal diseases. The distribution and prevalence of vector-borne diseases may be the most significant effect of climate change. The impact of climate change on the emergence and re-emergence of animal diseases has been confirmed by a majority of countries. Emerging zoonotic diseases are increasingly recognized as a global and regional issue with potential serious human health and economic impacts and their current upward trends are likely to continue. Coordinated international responses are therefore essential across veterinary and human health sectors, regions and countries to control and prevent emerging zoonoses. A new early warning and alert systems is developing and introducing for enhancing surveillance and response to zoonotic diseases. And international networks that include public health, research, medical and veterinary laboratories working with zoonotic pathogens should be established and strengthened. Facing this challenging future, the long-term strategies for zoonotic diseases that may be affected by climate change is need for better prevention and control measures in susceptible livestock, wildlife and vectors in Korea. In conclusion, strengthening global, regional and national early warning systems is extremely important, as are coordinated research programmes and subsequent prevention and control measures, and need for the global surveillance network essential for early detection of zoonotic diseases.