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Efficiency Study of 2D Diode Array Detector for IMRT Quality Assurance (2D 어레이 다이오드 검출기를 통한 IMRT 계산선량의 정확성 평가 및 효용성 연구)

  • Kim, Tae-Ho;Oh, Seung-Jong;Kim, Min-Joo;Jung, Won-Gyun;Chung, Jin-Beom;Kim, Jae-Sung;Kim, Si-Yong;Suh, Tae-Suk
    • Progress in Medical Physics
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    • v.22 no.2
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    • pp.61-66
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    • 2011
  • In this study, we evaluated the effect of grid size on dose calculation accuracy using 2 head & neck and 2 prostate IMRT cases and based on this study's findings, we also evaluated the efficiency of a 2D diode array detector for IMRT quality assurance. Dose distributions of four IMRT plan data were calculated at four calculation grid sizes (1.25, 2.5, 5, and 10 mm) and the calculated dose distributions were compared with measured dose distributions using 2D diode array detector. Although there was no obvious difference in pass rate of gamma analysis with 3 mm/3% acceptance criteria for the others except 10 mm grid size, we found that the pass rates of 2.5, 5 and 10 mm grid size were decreased 5%, 20% and 31.53% respectively according to the application of the fine acceptance criteria, 3 mm/3%, 2 mm/2% and 1 mm/1%. The calculation time were about 11.5 min, 4.77 min, 2.95 min, and 11.5 min at 1.25, 2.5, 5, and 10 mm, respectively and as the grid size increased to double, the calculation time decreased about one-half. The grid size effect was observed more clearly in the high gradient area than the low gradient area. In conclusion, 2.5 mm grid size is considered acceptable for most IMRT plans but at least in the high gradient area, 1.25 mm grid size is required to accurately predict the dose distribution. These results are exactly same as the precious studies' results and theory. So we confirmed that 2D array diode detector was suitable for the IMRT QA.

Intensity Modulated Radiation Therapy Commissioning and Quality Assurance: Implementation of AAPM TG119 (세기조절방사선치료(IMRT)의 Commissioning 및 정도관리: AAPM TG119 적용)

  • Ahn, Woo-Sang;Cho, Byung-Chul
    • Progress in Medical Physics
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    • v.22 no.2
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    • pp.99-105
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    • 2011
  • The purpose of this study is to evaluate the accuracy of IMRT in our clinic from based on TG119 procedure and establish action level. Five IMRT test cases were described in TG119: multi-target, head&neck, prostate, and two C-shapes (easy&hard). There were used and delivered to water-equivalent solid phantom for IMRT. Absolute dose for points in target and OAR was measured by using an ion chamber (CC13, IBA). EBT2 film was utilized to compare the measured two-dimensional dose distribution with the calculated one by treatment planning system. All collected data were analyzed using the TG119 specifications to determine the confidence limit. The mean of relative error (%) between measured and calculated value was $1.2{\pm}1.1%$ and $1.2{\pm}0.7%$ for target and OAR, respectively. The resulting confidence limits were 3.4% and 2.6%. In EBT2 film dosimetry, the average percentage of points passing the gamma criteria (3%/3 mm) was $97.7{\pm}0.8%$. Confidence limit values determined by EBT2 film analysis was 3.9%. This study has focused on IMRT commissioning and quality assurance based on TG119 guideline. It is concluded that action level were ${\pm}4%$ and ${\pm}3%$ for target and OAR and 97% for film measurement, respectively. It is expected that TG119-based procedure can be used as reference to evaluate the accuracy of IMRT for each institution.

Compare the Clinical Tissue Dose Distributions to the Derived from the Energy Spectrum of 15 MV X Rays Linear Accelerator by Using the Transmitted Dose of Lead Filter (연(鉛)필터의 투과선량을 이용한 15 MV X선의 에너지스펙트럼 결정과 조직선량 비교)

  • Choi, Tae-Jin;Kim, Jin-Hee;Kim, Ok-Bae
    • Progress in Medical Physics
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    • v.19 no.1
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    • pp.80-88
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    • 2008
  • Recent radiotherapy dose planning system (RTPS) generally adapted the kernel beam using the convolution method for computation of tissue dose. To get a depth and profile dose in a given depth concerened a given photon beam, the energy spectrum was reconstructed from the attenuation dose of transmission of filter through iterative numerical analysis. The experiments were performed with 15 MV X rays (Oncor, Siemens) and ionization chamber (0.125 cc, PTW) for measurements of filter transmitted dose. The energy spectrum of 15MV X-rays was determined from attenuated dose of lead filter transmission from 0.51 cm to 8.04 cm with energy interval 0.25 MeV. In the results, the peak flux revealed at 3.75 MeV and mean energy of 15 MV X rays was 4.639 MeV in this experiments. The results of transmitted dose of lead filter showed within 0.6% in average but maximum 2.5% discrepancy in a 5 cm thickness of lead filter. Since the tissue dose is highly depend on the its energy, the lateral dose are delivered from the lateral spread of energy fluence through flattening filter shape as tangent 0.075 and 0.125 which showed 4.211 MeV and 3.906 MeV. In this experiments, analyzed the energy spectrum has applied to obtain the percent depth dose of RTPS (XiO, Version 4.3.1, CMS). The generated percent depth dose from $6{\times}6cm^2$ of field to $30{\times}30cm^2$ showed very close to that of experimental measurement within 1 % discrepancy in average. The computed dose profile were within 1% discrepancy to measurement in field size $10{\times}10cm$, however, the large field sizes were obtained within 2% uncertainty. The resulting algorithm produced x-ray spectrum that match both quality and quantity with small discrepancy in this experiments.

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Change of Heart Rate Variability in Depressive Disorder after Physical or Psychological Stress (우울장애 환자에서 육체적 및 정신적 스트레스 시 심박변이도의 변화)

  • Lee, Jong-Hwa;Yu, Jaehak;Ryu, Seung-Ho;Ha, Ji-Hyeon;Jeon, Hong-Jun;Park, Doo-Heum
    • Sleep Medicine and Psychophysiology
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    • v.25 no.1
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    • pp.15-20
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    • 2018
  • Objectives: This study was designed to assess the change of heart rate variability (HRV) at resting, upright, and psychological stress states in depressive disorder patients. Methods: HRV was measured at resting, upright, and psychological stress states in 62 depressive disorder patients. We used visual analogue scale (VAS) score to assess tension and stress severity. Beck depression inventory (BDI) and state trait anxiety inventories I and II (STAI-I and II) were used to assess depression and anxiety severity, respectively. Differences between HRV indices and VAS score were evaluated using paired t-tests. Gender difference analysis was conducted with ANCOVA. Results: SDNN (standard deviation of normal to normal intervals), LF/HF (low frequency/high frequency), and VLF (very low frequency) were significantly increased, while NN50 and pNN50 were significantly decreased in the upright position compared to resting state. SDNN, RMSSD (root mean square of the differences of successive normal to normal intervals), and VLF were significantly increased, while pNN50 was significantly decreased in the psychological stress state compared to resting state. SDNN, NN50, and pNN50 were significantly lower in an upright position compared to a state of psychological stress, and LF, HF, and LF/HF showed no significant differences Conclusion: The LF/HF ratio was significantly increased after physical stress in depressive disorder. However, the LF/HF ratio was not significantly increased after psychological stress, and the change in LF/HF ratio after physical stress and psychological stress did not significantly differ from each other. Significant increase in SDNN, NN50, and pNN50 in an upright posture compared to psychological stress suggests that depressive patients react more sensitively to physical stress than psychological stress.

An Evaluation of the Use of Statistical Methods in the Journal of Tuberculosis and Respiratory Diseases ([결핵 및 호흡기질환] 게재 논문의 통계적 기법 활용에 대한 평가)

  • Koh, Won-Jung;Lee, Seung-Joon;Kang, Min Jong;Lee, Hun Jae
    • Tuberculosis and Respiratory Diseases
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    • v.57 no.2
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    • pp.168-179
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    • 2004
  • Background : The statistical analysis is an essential procedure ensuring that the results of researches are based on evidences rather than opinion. The purpose of this study is to evaluate which statistical techniques are used and whether these statistical methods are used appropriately or not in the journal of Tuberculosis and Respiratory Diseases. Materials and Methods : We reviewed 185 articles reported in the journal of Tuberculosis and Respiratory Diseases in 1999. We evaluated the validity of used statistical methods based upon the checklist that was developed on the basis of the guideline for statistical reporting in articles for medical journals by International Committee of Medical Journal Editors. Results : Among 185 articles, original articles and case reports were 110 (59.5%) and 61 (33.0%) respectively. In 112 articles excluding case reports and reviews, statistical techniques were used in 107 articles (95.5%). In 94 articles (83.9%) descriptive and inferential methods were used, while in 13 (11.6%) articles only descriptive methods were used. With the types of inferential statistical techniques, comparison of means was most commonly used (64/94, 68.1%), followed by contingency table (43/94, 45.7%) and correlation or regression (18/94, 19.1%). Among the articles in which descriptive methods were used, 83.2% (89/107) showed inappropriate central tendency and dispersion. In the articles in which inferential methods were used, improper methods were applied in 88.8% (79/89) and the most frequent misuse of statistical methods was inappropriate use of parametric methods (35/89, 39.3%). Only 14 articles (13.1%) were satisfactory in utilization of statistical methodology. Conclusion : Most of the statistical errors found in the journal were misuses of statistical methods related to basic statistics. This study suggests that researchers should be more careful when they describe and apply statistical methods and more extensive statistical refereeing system would be needed.

Long-term Oxygen Therapy for Chronic Respiratory Insufficiency: the Situation in Korea after the Health Insurance Coverage: a Multi-center Korean Survey -Study for the Development and Dissemination of the COPD Guidelines, Clinical Research Center for Chronic Obstructive Airway Disease- (가정산소치료의 보험급여 실시 이후 처방 실태: 다기관 조사 -만성기도폐쇄성질환 임상연구센터 제3세부과제 만성기도폐쇄성질환 진료지침 개발/보급 연구-)

  • Park, Myung Jae;Yoo, Jee-Hong;Choi, Cheon Woong;Kim, Young Kyoon;Yoon, Hyoung-Kyu;Kang, Kyung Ho;Lee, Sung Yong;Choi, Hye Sook;Lee, Kwan Ho;Lee, Jin Hwa;Lim, Sung-Chul;Kim, Yu-Il;Shin, Dong Ho;Kim, Tae Hyun;Jung, Ki-Suck;Park, Yong Bum
    • Tuberculosis and Respiratory Diseases
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    • v.67 no.2
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    • pp.88-94
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    • 2009
  • Background: From November 2006, The national health insurance system in the Republic of Korea began to cover prescribed long-term oxygen therapy (LTOT) in patients with chronic respiratory insufficiency. This study examined the current status of LTOT after national health insurance coverage. Methods: Between November 1, 2006 and June 30, 2008, the medical records of patients who were prescribed LTOT by chest physicians were reviewed. The data was collected from 13 university hospitals. Results: 197 patients (131 male and 66 female) were prescribed LTOT. The mean age was 64.3${\pm}$13.0 years. The most common underlying disease was chronic obstructive pulmonary disease (n=103, 52.3%). Chest physicians prescribed LTOT using arterial blood gas analysis or a pulse oxymeter (74.6%), symptoms (14%), or a pulmonary function test (11.2%). The mean oxygen flow rate was 1.56${\pm}$0.68 L/min at rest, 2.08${\pm}$0.91 L/min during exercise or 1.51${\pm}$0.75 L/min during sleep. Most patients (98.3%) used oxygen concentrators. Only 19% of patients used ambulatory oxygen supplies. The oxygen saturation before and after LTOT was 83.18${\pm}$10.48% and 91.64${\pm}$7.1%, respectively. After LTOT, dyspnea improved in 81.2% of patients. The mean duration of LTOT was 16.85${\pm}$6.71 hours/day. The rental cost for the oxygen concentrator and related electricity charges were 48,414${\pm}$15,618 won/month and 40,352${\pm}$36,815 won/month, respectively. Approximately 75% of patients had a regular visit by the company. 5.8% of patients had personal pulse oxymetry. 54.9% of patients had their oxygen saturation checked on each visit hospital. 8% of patients were current smokers. The most common complaint with LTOT was the limitation of daily activity (53%). The most common complaint with oxygen concentrators was noise (41%). Conclusion: The patients showed good compliance with LTOT. However, only a few patients used an ambulatory oxygen device or had their oxygen saturation measured.

A Study on the Characteristics of Jobs in Academic Libraries According to Different Generations (대학도서관 업무의 시대별 변천에 따른 특성 연구)

  • Cho, Chul-Hyun
    • Journal of the Korean BIBLIA Society for library and Information Science
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    • v.26 no.1
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    • pp.135-170
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    • 2015
  • This study aimed to investigate the transition of academic libraries' jobs by developing a model based on a shift of library generations including Library 1.0, Library 2.0, and Library 3.0 corresponding to the shift of web generations and to explore generational characteristics of library duties as well. The research used three phases of procedure: literature review about different library generations; job analyses for academic libraries in South Korea and the U.S.A.; the Delphi technique in tree sequential order. The research findings were as follows. First of all, there were 170 duties that continued from Library 1.0 to Library 3.0. There were 58 duties which continued from Library 2.0 to Library 3.0 whereas three duties that continued from Library 1.0 to Library 2.0. In addition, three distinctive duties existed only in Library 1.0 whereas one unique duty was only in Library 2.0. Library 3.0 generated 25 new duties. Secondly, considering general characteristics which cover specific parts of individual duties, there was a significant increase in importance, difficulty, and frequency of library administration throughout the three generations. In terms of importance, difficulty, and frequency of collection development and management, there was a significant increase only from Library 2.0 to Library 3.0. Considering information organization, there was a significant decrease in importance from Library 1.0 to Library 2.0. In addition, there was a significant decrease in frequency and there was no significant difference in difficulty throughout the three generations. In the case of information service, while there was a significant increase in importance among three generations, there was a significant increase in difficulty only from Library 1.0 to Library 2.0. However, there was no generational difference in frequency. With the respect of information system development and management, there was a significant increase in importance and frequency throughout the three generations, but there was no significant difference in difficulty among three generations.

An Analysis of the Operational Productivity and Cost for the Utilization of Forest-biomass(I) - the Operational time and Productivity - (산림바이오매스 이용을 위한 산림작업 공정 및 비용 분석(I) -작업시간 및 공정 -)

  • Mun, Ho-Seong;Cho, Koo-Hyun;Park, Sang-Jun
    • Journal of Korean Society of Forest Science
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    • v.103 no.4
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    • pp.583-592
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    • 2014
  • This study was carried out to investigate the operational time and productivity of logging operation by chain saw, yarder attached on tractor, tower-yarder, mini-truck, mini-forwarder, and chipping operations by mini-chipper, large-chipper in order to develop the efficient logging operation system for utilization of forest-biomass. As a result, the average felling and bucking time using chain saw at the site 1 and 2 was observed to be 182.7 sec/cycle and 518.5 sec/cycle respectively. The average yarding time was 202.5 sec/cycle using yarder attached on tractor and 295.1 sec/cycle using tower-yarder. The average forwarding time was 2,073 sec/cycle using mini-truck and 2,248.4 sec/cycle using mini-forwarder. The operational time of felling and bucking using chain-saw can be delayed according to the direction of fallen trees. The selection of felling direction is very important to yarding operation because the direction between width-yarding and felling are interrelated. Productivity can be improved through educating and training operators in the yarding operations. Mini-forwarder is needed to use because of higher productivity and lower cost than mini-truck. The operational productivity of felling and bucking by chain saw was $66.96m^3/man{\cdot}day$ and $43.86m^3/man{\cdot}day$ at site 1 and 2 respectively. The yarding productivity was $5.68m^3/man{\cdot}day$ by yarder attached on tractor, $10.74m^3/man{\cdot}day$ by tower-yarder. The forwarding productivity was $21.29m^3/man{\cdot}day$ by mini-truck, $28.57m^3/man{\cdot}day$ by mini-forwarder. The chipping productivity was $4.42m^3/man{\cdot}day$ by mini-chipper, $21.87m^3/man{\cdot}day$ by large-chipper.

Parents' Satisfaction on Foodservice Quality of Kindergartens in Chungbuk Province (충북지역 유치원 급식품질에 대한 학부모 만족도)

  • Lee, Joo-Young;Lee, Young-Eun
    • Journal of the Korean Society of Food Science and Nutrition
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    • v.39 no.4
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    • pp.613-623
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    • 2010
  • The purpose of this study was to examine parents' perceptions towards the importance and performance levels of foodservices quality at kindergartens. The questionnaire was developed to measure the thirty-one quality attributes of foodservice operations. A questionnaire survey was conducted to 500 parents and the return rates were 62.4%. The survey period was from July 15 to August 8, 2008. The parents had a high level of perception toward the need for foodservice, earning 4.46 points out of 5 point. Their perceptions of foodservice quality were examined by six dimensions of importance and performance level. While the parents gave 4 points or greater of 5 points to most quality attributes of importance level, they gave 4 points or less out of 5 points to most quality attributes of performance level. As for the importance and performance level of the quality dimensions of foodservice, parents regarded sanitation as the most important dimension. IPA showed that 'ventilation', 'sanitation of tableware' and 'sanitation of dining tables and chairs' were included as 'focus' areas. The overall satisfaction level for foodservice was 3.74 out of 5 points A higher level of satisfaction was shown at self-operated foodservice system of kindergartens. According to multiple regression analysis, 46.3% of the variance in the respondents' overall satisfaction scores was explained by factors such as food, menu and price, facilities, sanitation, atmosphere and foodservice effects.

Antioxidant Activities and Quality Characteristics of Cookies Supplemented with Mulberry Pomace (건오디박 첨가 쿠키의 품질특성 및 항산화성)

  • Jeon, Hye-Lyun;Oh, Hye-Lim;Kim, Cho-Rong;Hwang, Mi-Hyun;Kim, Hyung-Don;Lee, Sang Won;Kim, Mee Ree
    • Journal of the Korean Society of Food Science and Nutrition
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    • v.42 no.2
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    • pp.234-243
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    • 2013
  • The aim of this study was to evaluate the quality characteristics and antioxidative properties of cookies supplemented with mulberry pomace (0%, 4%, 8%, 12%). The bulk density, spread ratio, and leavening rate of cookies decreased with increasing amounts of mulberry pomace. The lightness and b value (of the Hunter color system) decreased based on the amount of mulberry pomace. The pH of cookies decreased (acidity increased) with increasing mulberry pomace. The soluble solid content increased according to the amount of added mulberry pomace, but the amount of reducing sugars decreased. In texture analysis, cookies with 12% mulberry pomace had the highest hardness. Total phenol and flavonoid content increased according to the amount of mulberry pomace added. Antioxidant activities, such as DPPH radical scavenging, hydroxyl radical scavenging, ABTS radical scavenging, and FRAP were highest in cookies with 12% mulberry pomace. In the sensory evaluation, sensory scores for color, taste, flavor, texture, and overall preference were highest in cookies with 8% mulberry pomace. Thus, our results suggest that the optimum amount of mulberry pomace to add to cookies is 8%.