• 대한한의학회지
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• 제38권3호
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• pp.13-29
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• 2017

Objectives: The objective of this review is to investigate the use of conventional Western medicine (WM) and complementary and alternative medicine (CAM) on leg cramps. Leg cramps are the occurrence of muscular spasm in the leg muscles which occur frequently in the elderly and are frequently observed in the clinical field. Methods: Relevant clinical studies were searched from five medical databases including PubMed, KISS, RISS, OASIS, and J-STAGE. Systematic review, clinical studies, and clinical practice guideline were included in this review. Results: In total, 27 clinical studies, 9 systematic review and meta-analysis, and 1 clinical practice guideline met the inclusion criteria. Included studies were classified and analyzed according to the type of intervention. Studies on quinine and magnesium have been most studied in WM and CAM, respectively. Although quinine shows some clinical effects on leg cramps, however, the risk of side effects are suggested. In addition, magnesium failed to improve the clinically significant effects in most studies. Five case reports using Oriental herbal medicine (OHM) were included and OHMs were effective in improving leg cramps without side effects, however, the quality of evidence was low. Clinical studies on other interventions were lacking. Conclusions: The results of this study indicate that there is no definite treatment standard for leg cramps until now, and there are limitations such as low level of evidence and side effects for each treatment. OHM can be an effective alternative to conventional intervention on leg cramps, therefore, related clinical studies are needed.

• 대한본초학회지
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• 제26권4호
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• pp.39-47
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• 2011

Objective: The roots, leaves, flowers, stems and seeds of Cirsium japonicum var. ussuriense are often used in treatment of human diseases such as hemorrhage, blood congestion and inflammation. Focusing our attention on natural and bioavailable sources of antioxidants and anti-inflammation, we undertook to investigate the antioxidant and anti-inflammatory properties of Cirsium japonicum var. ussuriense used as a folk medicine in Korea. Methods: The extracts of the leaves, stems, flowers, seeds and roots from C. japonicum var. ussuriense were prepared by extracting with water or 80% ethanol. Total flavonoids and polyphenols were measured by a colorimetric assay. The free radical scavenging activity of the extract was analyzed by the DPPH (1,1-diphenyl-2-picryl hydrazyl), ABTS (2,2'-azino-bis(3-ethylbenzthiazoline-6-sulfonic acid) and Griess reagent assay. An oxidative product of nitric oxide (NO), was measured in the culture medium by the Griess reaction. The level of prostaglandin $E_2$ ($PGE_2$) was measured by enzyme-linked immunosorbent assay. The expressions of inducible nitric oxide synthase (iNOS) and cyclooxygenase-2 (COX-2) were measured by Western blot analysis. Results: Total flavonoid and polyphenol amounts of the leaves (CLE) and flowers (CFE) showed higher than those of the seed extract (CSE), stem extract (CSTE) and roots (CRE). CLE and CFE also showed the high antioxidant activities such as DPPH, NO-like and ABTS radical scavenging activity. An antioxidant activities of these water extracts showed higher than those of 80% ethanol extracts. We investigated the anti-inflammatory effects of CLE on lipopolysaccharide (LPS)-stimulated RAW 264.7 cells. CLE significantly suppressed the levels of the inflammatory mediators such as NO and prostaglandin $E_2$ ($PGE_2$) in dose dependant. Furthermore, the levels of iNOS and COX-2 protein expressions were markedly suppressed by the treatment with CLE extract in a dose dependent manner. Conclusions: These results suggest that CLE water extract has a higher anoxidant and anti-inflammatory activity, these properties may contribute to the oxidative and inflammatory related disease care.

• Journal of Yeungnam Medical Science
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• 제22권1호
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• pp.13-26
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• 2005

Atrial fibrillation (AF) is the most common cardiac rhythm disturbance, which carries significant cardiovascular morbidity and mortality. The medical treatment for AF is cumbersome and unsatisfactory, which has highlighted the need to develop alternative treatments for AF. The recent discovery that AF is often initiated by atrial ectopic beats has resulted in treatments designed to target the ectopic sources, particularly those within the pulmonary veins. Building on the pioneering work of Cox et al., a recent reported series demonstrated the feasibility of treating patients undergoing cardiac surgery for other structural heart diseases with limited, left-atrial ablation lesion sets using alternative energy sources. As less complex modifications of the Maze procedure have been developed, a number of energy sources have been introduced to create of electrically isolating lesions within the atria. These sources have been used both endocardially in arrest heart procedures as well as epicardially in a beating heart setting. This review summarizes the recent advances in surgery for AF that will aid in the development of an effective, minimally invasive surgical procedure to cure patients with AF.

• 성인간호학회지
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• 제19권1호
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• pp.98-108
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• 2007

Purpose: To compare the health promoting behavior in rural elderly people by complementary alternative medicine(CAM) utilization. Methods: The data were collected from March 06th to May 26th, 2006. The participants were 207 rural elderly persons in Korea. Data were collected using structured questionnaires and analyzed with the SAS win 8.0 program. Results: The rate of using CAM was 60.9%. Non-religious, perceived poor health and high concerns about health group used it more. The most common type was oriental medicine(35.7%), the most common motive was body protection(21.2%) and major source of information was other patients(35.9%). Almost all the subjects(90%) were satisfied with using CAM. The average score for the health promoting behavior was $2.67{\pm}.32$(range 1.65-3.71). The average scores for each subscale were, personal communication 2.98, self-actualization 2.79, nutrition 2.78, health responsibility 2.58, exercise 2.40, stress management 2.38. Significant differences in health promoting behavior were found according to CAM utilization: personal communication, self actualization. Conclusion: There were differences health promoting behavior between the elderly CAM utilization: Systemic guidelines of CAM use are needed.

• 동서간호학연구지
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• 제15권2호
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• pp.102-109
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• 2009

Purpose: The study was conducted to ascertain the use of the complementary alternative medicine (CAM) in stroke patients, in order to provide the appropriate CAM information to patients recovering from stoke. Methods: Subjects were 201 stroke patients who were randomly selected from a health care center and a welfare center. Data from a self-administered questionnaire collected from February to April 2009 was analyzed using SPSS/WIN 12.0. Results: Subjects averaged 67.4-yr-of-age. Of the 201 subjects, 69.2% had used CAM. CAM use was statistically significant in diagnosis, duration of post stroke, paralysis, and education about CAM. CAM was used in the mid-portion of treatment by 47.3% of the subjects, and 41.7% used it for more than a year. Of those using CAM, 52.7% of the subjects responded that their reason was the belief in the treatment's beneficial effects. Of the subjects 89.2% reported most frequent use of oriental medicine. Conclusions: The majority of stroke patients surveyed frequently and continuously used CAM in their mid-period of treatment expecting positive effects.

• 한국방사선학회논문지
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• 제1권2호
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• pp.37-53
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• 2007

일부 지역의 일반인을 대상으로 대체요법에 대한 개인적 인식 정도와 이용경험을 파악하여 대체요법의 효율적 이용 방안을 연구하고 대체요법의 발전을 모색하는데 그 목적을 두고 본 연구를 시행하였다. 본 연구를 시행하기 위해 전남의 일부 지역 성인의 일반인을 연구자의 편의에 의해 선정하여 300명을 대상으로 설문조사를 실시하였다. 본 연구를 통하여, 첫째, 대체요법에 대한 지식 정도는 설문에 응답한 응답자 중 '약간 안다' 44.4%였다. 둘째, 대체요법의 '이용 경험은 있다.'는 응답자가 22.6%로 매우 낮았으나 이는 설문에 앞서 대체요법의 범주를 제시하지 않아 대체요법에 대한 용어의 이해 정도가 낮은 이유로 보여 진다. 셋째, 248명의 응답자 중 166명이 대체요법을 이용하고 있다고 응답했다. 이는 대체요법의 범주를 미리 제시하지 않아 대체요법의 범주에 대한 이해의 차이로 해석되어지며 본 질문 사항에서 대체요법의 범주를 이해한 것으로 보여 진다. 넷째, 연구대상자들이 가장 교육받고 싶은 요법으로 남자는 대체요법을 교육받고 싶은 1순위에 41명이 침술(수지침, 사혈 등)을 교육받고 싶어 했고, 여자는 대체요법을 교육받고 싶은 1순위에 20명이 요가를 교육받고 싶어 하였다. 따라서 대체요법 교육에 있어 남녀의 특성을 고려하여 교육을 시킬 때 더욱 효과적이 될 것임을 알 수 있었다. 대체요법에 대한 종류와 그 효능을 입증 할 수 있는 연구와 더불어 체계적인 홍보와 교육에 있어 적극적인 노력이 필요하다고 사료된다.

• 농촌의학ㆍ지역보건
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• 제33권2호
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• pp.181-192
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• 2008

Objective: The use of complementary and alternative medicine (CAM) is common especially among patients with osteoarthritis The aim of this study was to investigate the utilization rate and expenditures of patients who use CAM. Method: Two hundred seventy four patients with osteoarthritis were interviewed by a telephone survey. A structured questionnaire about sociodemographic features and type, cost, satisfaction and reason of CAM utilization was used Results: Among 274 patients with osteoarthritis, 251 patients(91.6%) had used at least one type of CAM during six months. There was a significant difference in sex (female), age (70 years), medical security (insurance), educational level between the user and non-user of CAM. Hyperthermia was the most use. The average cost for CAM utilization was 120 thousands won/person during six months and there was no difference in sociodemographic features among the out-of-pocket cost of users. The scores of satisfaction for CAM use were ranged between 60-70. Conclusions: CAM became a popular source of health care because of elderly and lay referral system. And Korean spent a substantial amount of out-of-pocket money on CAM without benefit. Health care system and professionals should pay more attention to CAM, make a evidence for CAM.

• 동의신경정신과학회지
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• 제27권4호
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• pp.235-248
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• 2016

Objectives: The aim of this review was to investigate whether evidence of complementary and alternative medicine (CAM) was reflected in clinical practice guidelines (CPGs) for insomnia based on relevant clinical trials. Methods: We conducted a systematic search on domestic and international CPG databases and medical databases. In addition, we conducted manual searches of relevant articles. Three authors independently searched and selected relevant studies; any disagreement was resolved by discussion. We extracted and analyzed the following data: published language, country, development group, participants, interventions, presence or absence of recommendations for CAM, level of evidence, grade of recommendation for CAM, and methods of development. Results: We identified 8,241 records from domestic and international databases, and 22 CPGs were included. Eleven of the 22 CPGs mentioned CAM interventions including herbal medicine, relaxation, acupuncture moxibustion, Tai Chi, meditation, hypnosis, biofeedback, Tuina, and external herbal medicine. However, most of the CPGs indicated 'no recommendation' or 'weak recommendation' for CAM interventions. Only Valeriana dageletiana Nakai and relaxation were considered to have experimental evidence. Valeriana dageletiana Nakai was recommended for improvement of sleep latency, sleep maintenance, total sleeping time, and sleep cycle. Relaxation was recommended as effective intervention for relieving physical and psychological arousal. Conclusions: Despite systematic reviews and randomized controlled trials on CAM for insomnia, most of the CPGs for insomnia did not reflect the evidence obtained. Further CPGs for insomnia should be developed by considering the current advanced studies in the field of CAM.

• 한국산학기술학회논문지
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• 제14권6호
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• pp.2812-2818
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• 2013

한의학과 대체의학은 그 뛰어난 진단 기술 및 처방과 치료 효과에도 불구하고 선호도에 있어 서양의학에 많이 떨어지고 있는 것이 현 실정이다. 마찬가지로 한의학과 밀접히 연계되어 있는 대체의학도 그 효과에 대한 입증이 과학적으로 규명이 되지 못하고 있는 것이 가장 큰 단점으로 여겨진다. 본 논문에서는 대체의학에서 흔히 사용하는 이침 요법이 실제 인체 장기 기능 강화에 도움이 되는 행위인지를 생체신호를 분석하는 방법 중 얼굴의 피부색 변화를 살펴보는 망진 이론을 적용하여 이를 규명하는 방법을 제안하고자 한다. 이를 위해 폐 이혈 반사점을 자극한 후의 우측뺨 색상을 측정하여 자극 전과의 비교, 분석 실험을 수행하였다. 또한 검증과 규명을 위해 우선적으로 인체가 폐에 미치는 영향의 분석에 필요한 영상 분석 요소를 파악하였다. 실험 결과, 폐 이혈 반사점 자극에 의해 우측뺨의 a값과 b값이 증가하는 결과가 도출되었다.

• Asian Pacific Journal of Cancer Prevention
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• 제15권6호
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• pp.2547-2554
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• 2014

Background: To evaluate the perception of cancer patients toward treatment services and influencing factors and to inquire about the use of complementary alternative medicine (CAM). Materials and Methods: Information was obtained through pre-tested structured questionnaires completed by cancer patients during treatment at King Abdulaziz University Hospital, Jeddah, Saudi Arabia. Results: Of 242 patients, 137 (64.6%) accepted to enter this study. Most were Saudi (n=93, 68%), female (n=80, 58%), educated at university (n=71, 52%), married (n=97, 72%) and with breast cancer (n=36, 26%). One-hundred (73%) patients were satisfied with the services provided; 61% were Saudi. Ninety-four (68%) respondents were satisfied with the explanation of their cancer. Twenty-eight (21.6%) patients received CAM, of them 54.0% received herbal followed by rakia (21.0%), nutritional supplements/vitamins (7.0%) and Zamam water (18.0%), with significant differences among them (p =0.004). Seven (5%) patients believed this therapy could be used alone; 34 (25%) patients believed it could be used with other treatments, regardless of whether they themselves used this therapy. Fifty-three (53%) satisfied patients felt they received enough support; 31 (58%) patients received support from family and friends; 22 (41.6%) patients received support from the health-care team. Patients who received information about their disease from their physicians and those who felt they had enough support were more satisfied. The patients who took alternative treatment were older age, mostly female and highly educated but values did not reach significance. Conclusions: We stress enhancing the educational and supportive aspects of cancer-patient services to improve their treatment satisfaction and emphasize the need for increasing the educational and awareness programs offered to these patients.