• Title/Summary/Keyword: alternative design

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HExDB: Human EXon DataBase for Alternative Splicing Pattern Analysis

  • Park, Junghwan;Lee, Minho;Bhak, Jong
    • Genomics & Informatics
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    • v.3 no.3
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    • pp.80-85
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    • 2005
  • HExDB is a database for analyzing exon and splicing pattern information in Homo sapiens. HExDB is useful for specific purposes: 1) to design primers for exon amplification from cDNA and 2) to understand the change of ORFs by alternative splicing. HExDB was constructed by integrating data from AltExtron which is the computationally predicted exon database, Ensemble cDNA annotation, and Affymetrix genome tile published recently. Although it may contain false positive data, HExDB is good starting point due to its sensitivity. At present, there areas many as 2,046,519 exons stored in the HExDB. We found that $16.8\%$ of the exons in the database was constitutive exons and $83.1\%$ were novel gene exons.

Generating Alternative Sewers Based on GIS and Simulation Technique (GIS 및 Simulation 기법에 의한 하수도관거 대안 생성)

  • 김형복;김경민
    • Spatial Information Research
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    • v.5 no.2
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    • pp.185-194
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    • 1997
  • Spatial decision support systems(SDffi), a new class of decision support system(DSS), result from the melding together of GIS and DSS, Planning support systems(PS5) add more advanced spatial analysis functions than GIS and intertemporal functions to the functions of SDSS. This paper reports the development of a planning support system providing a framework that facilitates urban planners and civil engineers in conducting coherent deliberations about the generation of satisficing sewers. 1he planning support system for the generation of satisficing sewers(PS5/GSS) was designed from the understanding that land use and development drive the demand for storm and sanitary sewers. Through four stages of supply, demand, alternative generation, and evaluation, PSS/GSS integrates basic planning, preliminary design, and engineering design of sewer. GIS and graphic user interface are excellent toolboxes for designing sewer networks, estimating the quantity of wastewater, and showing generated alternative sewers. A sewer model using simulation tedmique can generate an initial sewer. Users can define alternative sewers by the direct manipulation of sewer networks or by the manipulation of parameters in the sewer model. The sewer model evaluates the performance of the user defined alternatives.

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Estimation of seismic effective energy based parameter

  • Nemutlu, Omer Faruk;Sari, Ali;Balun, Bilal
    • Structural Engineering and Mechanics
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    • v.82 no.6
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    • pp.785-799
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    • 2022
  • The effect of earthquakes in earthquake resistant structure design stages is influenced by the highest ground acceleration value, which is generally a strength-based approach in seismic codes. In this context, an energy-oriented approach can be suggested as an alternative to evaluate structure demands. Contrary to the strength-based approach, the strength and displacement demands of the structure cannot be evaluated separately, but can be evaluated together. In addition, in the energy-oriented approach, not only the maximum effects of earthquakes are taken into account, but also the duration of the earthquake. In this respect, it can be said that the use of energy-oriented earthquake parameters is a more rational approach besides being an alternative. In this study, strength and energy-oriented approaches of earthquake parameters of 11 different periods of single degree of freedom systems were evaluated over 28 different earthquake situations. The energy spectra intended to be an alternative to the traditional acceleration spectra were created using the acceleration parameter equivalent to the input energy. Two new energy parameters, which take into account the effective duration of the earthquake, are proposed, and the relationship between the strength-oriented spectral acceleration parameters and the energy parameters used in the literature is examined by correlation study. According to the results obtained, it has been seen that energy oriented earthquake parameters, which give close values in similar period situations, will be a good alternative to strength oriented earthquake parameters. It was observed that the energy parameters were affected by the effective duration of the earthquake, unlike the strength-based parameters. It has been revealed that the newly proposed energy parameters considering the effective duration give good correlations. Finally, it was concluded that the energy parameters can be used in the design, and the newly proposed effective energy parameters can shorten the analysis durations.

A Design for the Symbol Park and the Waterfront Park for the Second Stage Development in the Eastern Rear Complex of Gwangyang Harbor (광양항 동측배후단지 2단계 사업지구 상징공원 및 수변공원 설계)

  • Hong Hyoung-Soon;Kim Do-Kyong;Jeong Han-Ho
    • Journal of the Korean Institute of Landscape Architecture
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    • v.34 no.3 s.116
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    • pp.104-119
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    • 2006
  • The eastern rear business complex of the Gwangyang Harbor (second stage) has undergone the 'alternative bid' process by which a construction company is selected based on their suggestions for an alternative plan and the bid for the construction expenses is based on the previously completed original plan, thereby implicitly accepting the arrangement and scale of the park which was presented in the original plan. It is possible, however, that the concept and plan of each park needs to be approached in a new way within the extent of given design guidelines. This study focuses on the alternative plan process and the Symbol Park (the second neighborhood park) and Waterfront Park (the third neighborhood park) among the five neighborhood parks in the eastern rear business complex (second stage). These two parks provide scale and function for the structure of the park and greenways system at the eastern rear complex. The neighboring waterway is a significant resource for emphasizing the pre-development features of the site. The alternative plan process focuses on determining the resources for the park's plan based on the environmental analyses of the site and utilizing the results. That is, through an analysis of the current state, all available resources are determined and the facilities and activities are derived based on these results. By this, Symbol Park and Waterfront Park reflect the regional features of the eastern rear complex, and these parks will feasibly perform the role of the region's key parte. The limit of this study is the fact that there is no chance for landscape architecture to actively play a role in the creation of the master plan, land utilization plan, and plan for the complex. Therefore there is a problem that the function scale and location of the park are not distributed appropriately in the rear complex. Also the plan for protecting the waterway's shore, a significant resource, only considers the structural stability of the engineering works, degrading the visual and ecological quality. These experiences will be used as a case for further designing the industrial complex and for the resulting park plan.

A Study of Goth Style Expressed in Contemporary Fashion (현대 패션에 표현된 Goth 스타일 연구)

  • Park Eun-Kyung;Chung Hyun-Sook
    • Journal of the Korean Society of Costume
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    • v.55 no.6 s.96
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    • pp.159-171
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    • 2005
  • The Goth style arouses Medieval syndrome, nostalgia and decadence, considering that Goth style shown in the contemporary fashion rend, tradition and fantasy that appeared in transition of the 21st century. This study is based on documents related to real Goth festivals and events to grasp various characteristics of Goth street style. The Goth style shown in high fashion classified the style on the basis of characteristics of camp culture from the viewpoint of bottom up from non-mainstream to mainstream with catwalk as the central figure. Considering appearance of Goth, property of subculture after the 1980s as alternative subculture as well phenomenon of latter subculture. Also it was possible to grasp attribute of lifestyle shown in music and fashion code from the viewpoint that alternative subculture was in pursuit of individual personality and autonomy. As an alternative subculture, Goth that appeared in UK from the late 1970s to the early 80s is considered new lifestyle, which means the scene of modern underground.