• Journal of Acupuncture Research
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• 제23권1호
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• pp.179-186
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• 2006

Background : Recently the demand was increasing on the data describing treatment rates and the outcome of Androgenetic Alopecia using Oriental Medicine. Thus this study was designed to observe androgenetic Alopecia treatment using Oriental Medicine including acupuncture and herb because there has been no such statistics. Objectives : Our purpose was determine whether oriental medicine treatment leads to clinical improvement in men with androgenetic alopecia. Methods : Eighty two Men, 17 to 53 years of age, with male pattern hair loss according to a modified Norwood/Hamilton classification scale(II to VI) were enrolled in this study. Patients were treated with multidisciplinary Korean oriental medicine treatment (herbal acupuncture, acupuncture, herb, chuna therapy) at twice a week for 6 months to 12 months. Efficacy was evaluated by patient and investigator assessment, and global photographic review. Results : Oriental medicine treatment improved scalp hair by all evaluation. Patient self assessment demonstrated that Oriental medicine treatment slowed hair loss, increased hair growth, and improvement appearance of hair. These improvements were corroborated by investigator assessments and assessments of photographs. Conclusion : Oriental medicine treatment has significant effects on the androgenetic alopecia. Longer follow up studies are needed to examine whether its effects last long enough for the patients with androgenetic alopecia.

• 한방안이비인후피부과학회지
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• 제29권4호
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• pp.182-188
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• 2016

Objectives : The purpose of this study is to report the effect of low level laser therapy and acupuncture on hair loss. Methods : The patient with alopecia caused by bed sore and alopecia areata was treated with 29 times of laser therapy, acupuncture and took herbal medicine during about 3 months. The treatment effect was evaluated by standardized photography. Results : Hair loss had shown a marked improvement. Entire scalp had been replaced with new hairs. Conclusions : LLLT(low level laser therapy) is effective method for treating alopecia. It can shorten the length of treatment of alopecia.

• 동의생리병리학회지
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• 제24권3호
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• pp.367-372
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• 2010

The purpose of this study is to make a basis of in vivo or clinical study about alopecia. We investigated the prescriptions of alopecia by researching oriental medicine literature. We found the prescriptions used for alopecia. And we surveyed the frequency and classification of the herbs used for alopecia. The results of this study were recorded as follows. The most frequently used single herbs in the prescriptions were Angelicae Gigantis Radix(當歸), Glycyrrhizae Radix(甘草), Poria(茯笭), Paeoniae Radix Alba(白芍藥). Herbs specifically frequently used in the prescriptions of alopecia were as follows. Polygoni Multiflori Radix(何首烏), Rehmanniae Radix(生地黃), Cuscutae Semen(菟絲子), Bupleuri Radix(柴胡), Scutellariae Radix(黃芩), Viticis Fructus(蔓荊子), Aconiti Iateralis Preparata Radix(附子). Herbs frequently used were classified by property. The result was as follows. (()-The number of herbs) 補益藥(32), 解表藥(18), 淸熱藥(15) 收澀藥(9), 活血祛瘀藥(8), 利水滲濕藥(8).

• 한방안이비인후피부과학회지
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• 제26권2호
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• pp.30-44
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• 2013

Objectives : The purpose of this study is to report the causes and the effects of korean medicine treatment on alopecia. Methods : 1050 patients with alopecia, who had visited oriental medical clinics from July 2011 to October 2012, were analyzed by self-assessments. And 153 patients of them were treated with korean medicine treatment for 3 months. Treatment results were evaluated by patients' self-assessments and global & enlarged photographic reviews. Results : 1. The gender ratio of male to female was 2:1 and most patients belonged to the 20~30 year old group. 2. Family history of baldness in alopecia patients was a total of 57.3%, paternal 44.4% and maternal 21.2%. 3. Subjective symptoms of fever in parietal region was a total of 97.4% in alopecia patients. 4. After 1 month treatment, the fever in the parietal region was decreased by 37.3% of patients. And their subjective hair loss was also significantly decreased. 5. After 3 months of treatment, the global photographic review was improved by 56.2% of the patients and the enlarged photographic review was significantly improved by 5.2% in patients' total hair count. Conclusions : A significant number of alopecia patients were young and less relative in genetic alopecia causes was less relevant than the past. Recent causes of alopecia were more concerned with the fever in parietal region. According to that reason, cooling effect korean medicine treatment was expected to be effective for febrile alopecia, and actually had significant effects on this study. For future studies, it's long term treatment and follow up studies are needed.

• 정신신체의학
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• 제8권2호
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• pp.165-171
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• 2000

연구목적 : 스트레스가 밀접하게 관련된 원형탈모증 환자들이 경험하는 생활사건, 이와 관련된 스트레스의 양, 이에 대한 대처방식 및 환자의 성격유형을 알아보아 이들 요소가 질병의 발병과 악화에 어떤 영향을 주는 지를 비교 분석하여 스트레스와 원형탈모증과의 관련성을 평가하고자 하였다. 방법 : 연구 대상은 피부과 외래를 방문한 원형탈모증 환자 43명과 대조군으로 피부진균감염증 환자 36명으로 하였다. 평가 도구로는 생활사건척도(Scale of Life Events), 대처방식척도(Coping Style Checklist)와 Eysenck A-유형성격검사로 세 가지의 설문조사를 실시하였다. 자료 분석은 연령을 보정한 공분산분석(analysis of covariance)을 적용하였다. 결과 : 원형탈모증군에서 생활 사건 수와 생활 사건의 총합이 유의하게 높았으나 대처 방식과 Eysenck A-유형성격에서는 유의미한 차이를 보이지 않았다. 결론 : 생활 사건에 대한 스트레스 양은 원형탈모증 환자군이 대조군에 비해 유의미하게 높은 수치를 보였고 이는 스트레스가 원형탈모증 발생에 기여한다는 기존의 연구들과 일치하는 소견이다. 후 스트레스와 원형탈모증과 보다 직접적인 연관 관계를 명확히 규명하여 궁극적으로 임상적으로 응용이 되어야 한다고 생각한다.

• 대한한의학회지
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• 제27권3호
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• pp.212-221
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• 2006

Objectives: This study was designed to investigate acupuncture treatment of alopecia patients by researching literature and to standardize acupuncture treatment. Methods: We extracted the parts about acupuncture treatment of alopecia which are called 'Tal Bal(說髮), 'Ban Dok'(斑禿), 'Tal Mo'(脫毛), 'Bal Rak'(髮洛), 'Wonhyung Talmo'(圓形脫老) from 2 ancient and 49 modern oriental medicine literal sources. We surveyed the frequency and characteristics of the acupoints used for treatment of alopecia, and the acupoint was classified according to its meridian or demonstration. The results of this study were recorded as follows: 1. The most frequently used acupoints were GB20(風紙), GV20(百會), BL13(膈兪), SP6(三陰交), ST36(足三里), BL23(腎兪), SP10(血海), LI11(曲池), in that order. 2. The most frequently used meridians were the urinary bladder meridian (足太湯膀胱經), the Governor Vessel(督豚), the spleen meridian(足少陰脾經), and the gall bladder meridian(足少陰膽經), in that order 3. The most frequently used regions were the head, under the knee, and the back, in that order. 4. The most frequently used Jang organs and Bu organs were the spleen(脾), the stomach(胃), the liver(肝), the gall bladder(擔), the lungs(肺), and the large intestines(大腸), in that order. 5. Common methods of differentiation of alopecia are Hyulyulsaengpung(血熱生風), Gichehyutea(氣滯血瘀), Gihyulyanghea(氣血兩瘀), and Gansinbugok(肝腎不足). Conclusions : For treatment of alopecia, all the patient's symptoms, including alopecia, must taken into consideration and demonstrated.

• 대한한의학회지
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• 제25권1호
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• pp.152-160
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• 2004

Backgrounds : Androgenetic alopecia is a relatively common disorder, but its precise mechanism is not elucidated. There are two commercial drugs approved by FDA. One(finasteride) has an inhibition activity of 5$\alpha$-reductase(type 2) and the other(minoxidil) has a vasodilation activity. Objectives : A verified herbal remedy for baldness is needed for medicinal treatment or preventing alopecia, which could be demonstrated by alopecia-related in vitro & in vivo tests Methods : On the basis of oriental pharmacognosy, we classified many herbal medicines into four groups (malnutrition, aging, alopecia and gray hair) according to its effect. The mitosis induction of hairy dermal papillae cell and the metabolic inhibition for type 2 $5{\alpha}-reductase$ were tested with five herbal extracts. Also, five herbal extracts were added to the normal essence formulation (HHRHG0202-80) in ranges of 0.1~0.3%, which was applied two-mouse models to validate each hair growing activity in vivo. Results : Stimulation of follicular papillae cell proliferation was observed in treatment of three herbal extracts (Glycyrrhizae radix:159.7%, Corni fructus : 144.7%, and Coicis semen : 136.6%) at a dose of $10\mu\textrm{g}/ml$. Three herbal extracts (Biotae semen. Glycyrrhizae radix and Coicis semen) showed inhibitory activity for $5{\alpha}-reductase$(type 2) at 93.18%, 73.36% and 47.6%, respectively at the same dose. We observed the enhancement of hair growth activity in C57b1/6 mouse and the inhibition of alopecia in AGA mouse after topical administration of the hair essence. Conclusions : Hair essence product, which contains five medicinal plants, would be used for the remedy for male pattern baldness (MPB) and the other alopecia diseases.

• 대한한방내과학회지
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• 제38권2호
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• pp.235-239
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• 2017

This case study describes the effect of Bojungikki-tang on chemotherapy-induced alopecia. Alopecia is a well-documented cause of distress to patients undergoing cancer treatment, but no approved pharmacological treatment exists for chemotherapy-induced hair loss. A 70-year-old female diagnosed with a cholangiocarcinoma and liver metastasis received chemotherapy, including gemcitabine and cisplatin, every three weeks. As a result of the continuous chemotherapy, she suffered various toxicity-related side effects, including bone marrow suppression, general weakness, nausea, peripheral numbness, and hair loss. Bojungikki-tang was initially administered to improve the patient's general weakness and fatigue. After three months of treatment, the patient's hair loss and general condition improved, and the color of the new hair was dark, despite the chemotherapy. The treatment did not improve other symptoms, such as bone marrow suppression and peripheral numbness. This case suggests that Bojungikki-tang could have a beneficial effect on chemotherapy-induced alopecia.

• 한국수의병리학회지
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• 제7권1호
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• pp.5-9
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• 2003

Malignant catarrhal fever (MCF) is a systemic disease of ruminants caused by a gamma herpesvirus, ovine herpesvirus 2 (OvHV-2). Four 1-year old goats (Capra hircus), which were infected with MCF virus, OvHV-2, by being housed together with MCF virus-infected seep, were referred with a I-month history of chronic dermatitis. On the other hand, MCF virus-negative goats, which were isolated for negative control, had not those kinds of skin problems. Examination of the affected goats revealed generalized alopecia, patchy erythema, and superficial erosions with histologic evidence of mural folliculitis. Fungal culture tests and external parasite tests with the scraping skin samples were negative. However, polymerase chain reaction revealed the existence of MCF virus DNAs in the lesion. These results suggested that MCF virus may induce mural folliculitis and alopecia in goat.

• Annals of Clinical Neurophysiology
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• 제7권1호
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• pp.58-60
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• 2005

Myasthenia gravis (MG) is occasionally associated with other autoimmune diseases. Alopecia areata has been reported to coincide with MG, particularly with thymoma. A 14-year-old woman was diagnosed as having MG. Seven months before diagnosed with MG, her hair and eyebrows had began to disappear and alopecia areata was diagnosed. We report this patient as a rare case of MG associated with alopecia areata without thymoma.