• The Journal of Korean Medicine Ophthalmology and Otolaryngology and Dermatology
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• v.15 no.2
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• pp.169-182
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• 2002

Background: Allergic rhinitis(AR) is a heterogeneous disorder that despite its high prevalence is often undiagnosed. It is characterized by one or more symptoms including sneezing, itching, nasal congestion, and rhinorrhea. And it is frequently accompanied by symptoms involving the eyes, ears, and throat, including postnasal drainage. There are many different causes of rhinitis in children and adults. Approximately 50$\%$ of all cases of rhinitis are caused by allergy. In the case of rhinitis caused by allergens, symptoms arise as a result of inflammation induced by a gamma globulin E-mediated immune response to specific allergens such as pollens, molds, animal dander, and dust mites. The immune response involves the release of inflammatory mediators and the activation and recruitment of cells to the nasal mucosa. AR is similar to 鼻？, hypersensitive rhinitis in Oriental Medicine. I think hypersensitive rhinitis is including of AR, vasomotor rhinitis and non-allergic rhinitis related with eosinophil increased and so on. Purpose: To perform a clinical analysis of hypersensitive rhinitis including allergic rhinitis and estimate the efficacy of Oriental Medical treatment. Objective: We studied 96 patients who had visited our hospital with complaints of nasal symptoms from March 2000 to February 2002; they had the signs more than 2 - nasal obstruction, watery discharge, sneezing and eye or nasal itching. Parameters Observed & Methods: We treated them with acupuncture & herb-medication. Sometime they used aroma oil or external medicine. 1) the distribution of sex & age groups 2) the clinical type based on duration & the severity of symptom 3) the breakdown of complication & pasl history of Otolaryngologic or allergic disease 4) the clinical assessment and classification of rhinitis(sneezers and runners & blockers) 5) the associated symptoms and signs 6) the classification of Byeonjeung 7) the classification of prescriptions and 8) the efficacy of treatment. Result: 1. In the clinical type of based on duration, the intermittent type was 42.7$\%$ and the persistent was 57.3$\%$. 2. We observed the severity of symptoms based on the quality of life. The mild type was 24.0$\%$ and the moderate-severe was 76.0$\%$. 3. In the clinical assessment and classification of rhinitis, the sneezers and runners type was 69.8$\%$ and the blockers was 30.2$\%$. 4. The most common family history with otolaryngologic or allergic disease were allergic rhinitis(17.7$\%$), urticaria, paranasal sinusitis and T.B.(3.1$\%$). 5. The most common past history with otolaryngologic or allergic disease were paranasal sinusitis(14.6$\%$), atopic dermatitis and asthma(8.3$\%$). It was 31.3$\%$ they had a family history and 44.8$\%$, past history. 6. The most common complication was paranasal sinusitis(15.6$\%$). In decreasing order the others were otitis media with effusion(9.4$\%$), GERD and headache(6.3$\%$), asthma, bronchitis, nasal bleeding and allergic dermatitis(5.2$\%$). 7. Classification through Byeonjeung : ⅰ) 39 cases(34.9$\%$) were classified as showing Deficiency syndrome. The insuffficiency of Qi was 17.7$\%$, deficiency of Kidney-Yang, 12.5$\%$ and Lung-Cold, 10.4$\%$. ⅱ) 57 cases(59.4$\%$) were classified as showing Excess syndrome. The Fever of YangMing-meridian was 35.4$\%$, Lung-Fever, 24.0$\%$. 8. The efficacy of treatments showed: an improvement in 22cases(22.9$\%$); an improvement partly in 24 cases(25.0$\%$); no real improvement or changes in 16 cases(16.7$\%$); and couldn't check the results 18cases(18.6$\%$). Conclusion: We suggest that this study could be utilized as a standard of clinical Oriental Medical treatment when we treat hypersensitive rhinitis including allergic rhinitis.

• Journal of Preventive Medicine and Public Health
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• v.49 no.5
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• pp.329-341
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• 2016

Objectives: The goal of this study was to investigate the short-term effect of ambient air pollution on emergency department (ED) visits in Seoul for asthma according to patients' prior history of allergic diseases. Methods: Data on ED visits from 2005 to 2009 were obtained from the Health Insurance Review and Assessment Service. To evaluate the risk of ED visits for asthma related to ambient air pollutants (carbon monoxide [CO], nitrogen dioxide [$NO_2$], ozone [$O_3$], sulfur dioxide [$SO_2$], and particulate matter with an aerodynamic diameter <$10{\mu}m$ [$PM_{10}$]), a generalized additive model with a Poisson distribution was used; a single-lag model and a cumulative-effect model (average concentration over the previous 1-7 days) were also explored. The percent increase and 95% confidence interval (CI) were calculated for each interquartile range (IQR) increment in the concentration of each air pollutant. Subgroup analyses were done by age, gender, the presence of allergic disease, and season. Results: A total of 33 751 asthma attack cases were observed during the study period. The strongest association was a 9.6% increase (95% CI, 6.9% to 12.3%) in the risk of ED visits for asthma per IQR increase in $O_3$ concentration. IQR changes in $NO_2$ and $PM_{10}$ concentrations were also significantly associated with ED visits in the cumulative lag 7 model. Among patients with a prior history of allergic rhinitis or atopic dermatitis, the risk of ED visits for asthma per IQR increase in $PM_{10}$ concentration was higher (3.9%; 95% CI, 1.2% to 6.7%) than in patients with no such history. Conclusions: Ambient air pollutants were positively associated with ED visits for asthma, especially among subjects with a prior history of allergic rhinitis or atopic dermatitis.

• Clinical and Experimental Pediatrics
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• v.58 no.5
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• pp.190-193
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• 2015

Allergic bronchopulmonary aspergillosis (ABPA) is a hypersensitivity lung disease due to bronchial colonization of Aspergillus fumigatus that occurs in susceptible patients with asthma or cystic fibrosis. A 10-year-old girl was referred to the Department of Pediatric Pulmonology for persistent consolidations on chest radiography. Pulmonary consolidations were observed in the right upper and left lower lobes and were not resolved with a 4-week prescription of broad-spectrum antibiotics. The patient had a history of atopic dermatitis and allergic rhinitis but no history of asthma. She had no fever but produced thick and greenish sputum. Her breathing sounds were clear. On laboratory testing, her total blood eosinophil count was $1,412/mm^3$ and total serum IgE level was 2,200 kU/L. Aspergillus was isolated in the sputum culture. The A. fumigatus-specific IgE level was 15.4 kU/L, and the Aspergillus antibody test was also positive. A chest computed tomography scan demonstrated bronchial wall thickening and consolidation without bronchiectasis. An antifungal agent was added but resulted in no improvement of pulmonary consolidations after 3 weeks. Pulmonary function test was normal. Methacholine provocation test was performed, revealing bronchial hyperreactivity ($PC_{20}=5.31mg/mL$). Although the patient had no history of asthma or bronchiectasis, ABPA-seropositivity was suspected. Oral prednisolone (1 mg/kg/day) combined with antifungal therapy was started. Pulmonary consolidations began decreasing after 1 week of treatment and completely resolved after 1 month. This is the first observed and treated case of seropositive ABPA in Korean children without previously documented asthma.

• The Journal of Internal Korean Medicine
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• v.21 no.4
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• pp.565-573
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• 2000

Objective : This research was carried out to find out the general understanding of allergic diseases, the frequencies of allergic diseases and the attitude toward their oriental medical treatment(OMT) among common people. Methods : A total of 360 visitors at The 2nd International Exhibition on Oriental Medicine in 2000, participated in this research. We performed this survey with 22 items on the questionnaire. Results : Respondents knew the. fact that the allergic diseases were hereditary and could be affected by the living environment. 41.8% of the respondents had a past history of allergic diseases. Among the people who had allergic diseases, 63.5% had allergic rhinitis, which was the largest portion. Among them, 52.9% had a familial history. 81.5% of respondents with allergic diseases received western medical treatment for their allergies, 16.3% received both western and oriental medical treatment and 2.2% received OMT only. Among those who were treated for allergic disease, 62.0% were unsatisfied with the low effect of the treatment. To the point of excellence of OMT, 69.7%, which was the largest portion of respondents, believed that OMT could improve their constitutions. The problem with OMT was the high price of herbal medicine and this was the problem most frequently stated, by 51.4% of respondents. There was a positive attitude towards the effect of OMT, and respondents had a preference to receive OMT in the future(p<0.01). Conclusions : These days, it is a fact that the OMT for allergic diseases has a lower proportion to that of western treatment In order to increase the role of OMT, we think, oriental medical doctors need to develop an explanatory model of improving $people^{\circ}{\phi}s$ constitutions and should lower the cost of herbal medicine.

• The Journal of Korean Medicine
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• v.22 no.4
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• pp.29-36
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• 2001

Objectives: This study attempted to investigate the allergic histories and the distribution of offending allergens in the general public and further to help their diagnosis and treatment with Oriental Medicine. Methods: Allergic skin tests (AST) were performed and allergic histories were taken of 359 members of the general public who visited the International Exhibition on Oriental Medicine from Sept. 1 to Sept. 5, 2000. The allergen reagents for AST were three (House dust, D. farinae, Dog hair) and the control reagent was histamine solution. Results: 1.50.1 % of the subjects (n=359) were positive to AST. The ratio between males' positivity and females' was 1.06：1. 2. The younger the subjects were, the higher the positivity was. 3. The positive subjects' (n=180) positivity to three allergens was as follows: D. farinae 98.9%, House dust 30.0%, Dog hair 1.7%. 4. The younger the positive subjects were, the higher the positivity to House dust was. In contrast, the positivity to D. farinae was high in all age groups. 5.71.1 % of the positive subjects reacted positively to monotype allergen and 28.9% reacted positively to multiple allergens (2.46：1). The most common monotype allergen was D. farinae (98.4%) and the most common combination of multiple allergens was House dust and D. farinae (94.2%). 6.52.8% of the positive subjects (n=180) and 51.4% of the negative subjects (n=179) represented the history of allergic diseases. There was no relationship between allergic skin test and allergic diseases. Conclusion: To help in diagnosis and treatment with oriental medicine, research to analyze the relationship between allergic skin test and allergic diseases should be continued on the basis of Oriental medical theories.

• Journal of Korean Biological Nursing Science
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• v.15 no.4
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• pp.264-271
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• 2013

Purpose: The purpose of this study was to analyze the symptoms of allergic rhinitis among university students and assess their quality of life (QOL) in order to establish an effective program for university students with allergic rhinitis. Methods: The data were collected in May, 2012 in a university school health center. The collected data were analyzed in terms of frequency, percentage and mean for the symptom types and QOL among 131 university students with allergic rhinitis. An independent t-test was conducted to determine differences in QOL according to general and disease related characteristics. Results: Symptoms were reported in the following order: nasal obstruction, rhinorrhea, sneezing, and nasal itching respectively. The mean score of QOL of the participants was 2.24 (5 point). Nasal symptoms such as rhinorrhea (M=3.16) and nasal obstruction (M=3.12) had the highest score and affected QOL badly in the item analysis. QOL differed according to the diagnosis of allergic rhinitis history, skin test reaction, some symptoms and allergens. Conclusion: To establish an effective management program for increasing QOL among university students with allergic rhinitis, symptom management methods for nasal obstruction and rhinorrhea should be included in the program.

• Journal of Dental Anesthesia and Pain Medicine
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• v.23 no.3
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• pp.173-177
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• 2023

Local anesthetics are an essential part of pain control during dental treatment. Despite its effectiveness and safety, patients should constantly be aware of potential adverse effects, including allergic reactions. Allergic reactions to amide-type local anesthetics (LAs), such as lidocaine and mepivacaine, are rare compared to those to ester-type LAs. Herein, we report the case of a patient with a history of allergy to lidocaine and mepivacaine, with symptoms of itching, diffuse erythema of the wrists and hands, dizziness, and pectoralgia. This case report emphasizes the importance of collecting medical and dental histories of patients is necessary, and how an allergy test in the allergy and clinical immunology department helps select safe LAs for patients.

• Journal of Physiology & Pathology in Korean Medicine
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• v.16 no.2
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• pp.397-402
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• 2002

Clinical studies were done treated with aroma therapy in 22cases of patients for suffering allergic rhinitis. who were treated at Dept of Oriental respiratory internal medicine in the Hospital of Taejeon University from January 2001 to May 2001. The results were as follows. 1. In distribution of sex & age. 45.5% of them were man, and 54.5% of them were woman. Of those who were attached, 2. In distribution of occupation, 59% of them were student, 18% of them were housewife, 18% of them were white color, 9% Of them were blue color. 3. In distribution of the period of the clinical history, under six months was 32%, under 1 year was 9%, under 3 years was 27%, over 3 years was 32%. 4. In distribution of the seasonal contributing factor, most of them were perenial allergic rhinitis, others generally started in spring or winter. 5. In distribution of past history, 59% of them are none, 18% of them are asthma, 18% of them are atopic dermatitis, 5% of them are allergic dermatitis. 6. In distribution of family history, 46% of them are none, 27% of them are sibling line, 18% of them are paternal line, 9% of them are maternal line. 7. In distribution of symptom, the ratio of sneezing was 90%, nasal discharge was 81 %, nasal obstruction was 46%, pruritus was 41 %, headache was 31%, asthma was 22%, digestion disorder was 18%, tears was 9%, nosebreeding was 5%. 8. In distribution of diagnosis in descending order, wind-cold evil was 5%, spleen-lung energy asthnia was 31 %, lung-kidney asthnia was 64%. 9. In distribution of Herb medicine treatment, Tonggyu-tang was the most, the second was hyunggaiyunyo-tang. 10 In emotional change of patients aroma-therapy, only 14% of them felt good. 11. The total remedial value of the 22 patients was revealed 32.9%. 12. In proportion to grow older, the remedial value were decreased. 13. In proportion to the period of the clinical history was longer, the remedial value were decreased.

• The Journal of Pediatrics of Korean Medicine
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• v.13 no.2
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• pp.139-148
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• 1999

The purpose of this study was to prepare the new effective oriental medical treatments. This study was performed at Dongeui Oriental Medical Hospital from October, 1, 1999 to November, 30, 1999, and 59 patients with cough persisting for longer than 3 weeks were evaluated. The following results were obtained. 1. In sex, male was 32 patients(54.24%) and female was 27 patients(45.76%), and in age group, between 2 and 6 years was 43 patients(72.88%) as first. 2. In the distribution of complicated signs, sputum was 42 patients(7l.18%) as first, rhinorrhea was 24(40.68%) as second. 3. In the style of cough. attack on morning or sleeping time was 32 patients(54.24%) as first. 4. In the past history, pulmonary diseases, such as pneumonia, bronchitis were 10 patients(16.95%) as first. 5. In the family history of allergy, allergic dermatitis was 6 patients(10.l7%) and allergic rhinitis was 4 patients(6.78%)

• Journal of Dental Anesthesia and Pain Medicine
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• v.21 no.6
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• pp.583-587
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• 2021

Lidocaine is the most commonly used local anesthetic (LA) agent in various dental as well as oral and maxillofacial procedures. Although rare, adverse effects and allergic reactions to lidocaine have been reported. In patients with suspected allergy to LA or a history of such reaction, careful history-taking and allergy testing should be performed to choose an alternative LA agent to avoid any adverse effects. Here, we present two cases of delayed hypersensitivity reaction to lidocaine, wherein the patients presented with erythema, edema, and itching. Intradermal testing confirmed allergic reaction to lidocaine, and the patients underwent successful dental treatment using an alternative LA agent. This report highlights the importance of allergy testing prior to LA use considering the serious consequences of allergy to these agents and describes the management of such patients using an alternative LA agent.