• Title/Summary/Keyword: allergen

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System Architecture of Atopic Dermatitis Adjuvant for Children Using Wireless Sensor

  • Balitana, Maricel O.;Kim, Seok-Soo
    • International Journal of Contents
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    • v.4 no.2
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    • pp.1-6
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    • 2008
  • Pre schools with state of the art facilities that would provide not just academic excellence but also ensure the safety and provide efficient healthcare to their pupils relative to Atopic Dermatitis with Asthma is the main objective of this research One of the most promising applications of sensor networks is for human healthcare monitoring. Due to recent technological advances in sensor, low power microelectronics and miniaturization, and wireless networking enable the design and proliferation of this wireless sensor networks capable of autonomously monitoring and controlling environments. Thus, this research presents the utilization of such microelectronic sensor and plots the hardware and software architecture of a wireless sensor network system with real-time pupil monitoring that integrates vital sign sensors, location sensor and allergen sensor. This proposed architecture for wearable sensors can be used as active tags which can track pupil's location within the school's premises, identify possible atopic dermatitis with asthma allergens, it would monitor and generate a health status report of the pupil.

Inhibitory effects of synthetic isoflavone compounds on IL-5 bioactivity

  • Ju, Jung-Hun;Jung, Sang-Hun;Cho, Soo-Hyun;Dang, The-Hung;Lee, Jee-Hyun;Kim, Mi-Kyeong;Lee, Seung-Ho;Ryu, Jae-Chun;Min, Kyung-Rak
    • Proceedings of the PSK Conference
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    • 2003.04a
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    • pp.210.2-211
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    • 2003
  • Eosinophilic inflammation is the main histological correlate of airway hyperresponsiveness and tissue injury in the pathogenesis of bronchial asthma. Interleukin (IL)-5 appears to be one of main proinflammatory mediators that induce eosinophilic inflammation. Allergic IL -5-deficient mice do not generate eosinophilia in the bone marrow, blood or lung in response to allergen provocation. (omitted)

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Protection Againse Histamine-Induced Bronchial constriction and Asphyxia by In-Sam-Yun-Pai-San-Ga-Gam-Bang (인삼윤폐산가감방(人蔘潤肺散加減方)이 Histamine으로 유발(誘發)된 기관지수축(氣管支收縮)과 질식(窒息)에 대(對)한 보호효과(保護效果))

  • Choe, Yun-Jeong;Kim, Jang-Hyeon;Mun, Jun-Jeon
    • The Journal of Dong Guk Oriental Medicine
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    • v.2 no.2
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    • pp.57-68
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    • 1993
  • In humans, an immediate allergic response to an allergen snay appear as either bronchial asthma unaccompanied by anaphylaxis or a severe bronchial constriction and spasm accompanied by anaphylaxis. Much experimental evidence with isolated asthmatic tissues has shown that histamine is released during the allergic reaction. Paradoxically, antihistamine treatment is ineffective in reversing bronchial asthma or anapllylaxis in a man. The present study objective is to search for protective agents(In-Sam-Yun-Pai-San-Ga-Gam-Bang) against bronchial constriction in treating a anaphylaxis. The result from this study is as follows. A single dose of In-Sam-Yun-Pai-San-Ga-Gam-Bang extract(3ml/kg body weight) 2 hrs prior to histamine-induced bronchial constriction test demonstrated significant protection. Based on the above result, It is considered that In-Sam-Yun-Pai-San-Ga-Gam-Bang can be used in bronchial asthma.

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Effectiveness for Beauty Improvement of Geranium essential oil on Skin Troubles by Surfactant (계면활성제에 의해 손상된 피부의 Geranium essential oil 미용증진 효과)

  • Choi, Jeung-Suk
    • Journal of the Korean Society of Fashion and Beauty
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    • v.2 no.2 s.2
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    • pp.101-106
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    • 2004
  • Allergic contact dermatitis is a common skin disease resulting from specific immunologic sensitization to topically applied various allergen. The Purpose of this study was to investigate skin morphologic cahnges by light microscopic and scanning electron Microscope, changes of protein band by SDS-PAGE(SDS-polyacrylamide gel electrophoresis) in the skin effectiveness for beruty improvement of Geranium essential oil on skin troubles by surfactant. The results of the study are as follows, 1. From the observed result of FE-Scanning Electron Microscope, groups treated by Geranium essential oil in group treated Geranium essential oil during 1 week in surfactant treated group during 1 week, the group was repaired in irregularity surface of tissue by alleviate-keratinization of Geranium essential oil. 2. As a result of protein analysis the group treated on surfactant was rised protein upper range of 97,0004a11on by hyper-keratinization and group treated during 1 week by surfactant was decreased protein below range of 43,000dalton.

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A practical view of immunotherapy for food allergy

  • Song, Tae Won
    • Clinical and Experimental Pediatrics
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    • v.59 no.2
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    • pp.47-53
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    • 2016
  • Food allergy is common and sometimes life threatening for Korean children. The current standard treatment of allergen avoidance and self-injectable epinephrine does not change the natural course of food allergy. Recently, oral, sublingual, and epicutaneous immunotherapies have been studied for their effectiveness against food allergy. While various rates of desensitization (36% to 100%) and tolerance (28% to 75%) have been induced by immunotherapies for food allergy, no single established protocol has been shown to be both effective and safe. In some studies, immunologic changes after immunotherapy for food allergy have been revealed. Adverse reactions to these immunotherapies have usually been localized, but severe systemic reactions have been observed in some cases. Although immunotherapy cannot be recommended for routine practice yet, results from recent studies demonstrate that immunotherapies are promising for the treatment of food allergy.

Changes in Allergenicity and Digestibility of Egg and Milk by Heat Treatment (가열처리에 따른 우유와 달걀의 Allegenicity의 변화와 소화율에 관한 연구)

    • Journal of the East Asian Society of Dietary Life
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    • v.11 no.2
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    • pp.104-111
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    • 2001
  • The first purpose of this study was to determine the changes in the allergenicity of milk and egg with heat treatment. The allergenicity of milk and egg is known to have a strong antigen. The second purpose of this study was to observe changes of disestibility of milk and egg after heat treatment. For this study, passive cutaneous anaphylaxis(PCA) inhibition experiment by using guinea pig and nonprotein nitrogen(NPN)experiment were attempted. The result were following: 1. The allergenicity of both milk and egg was reduced by heat treatment. 2. The degree of hydrolysis and PCA inhibition increased with longer heating time. 3. The increse in both the degree of hydrolysis and PCA inhibition of milk was higher than that of egg. 4. Egg contained a greater amount of allergen than milk after heat treatment. 5. The digestibility of both milk and egg was reduced by heat treatment. 6. The digestibility was reduced further by increasing heating time. 7. The digestibility of egg was lower than that of milk after the treatment.

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The House Dust Mite Allergen, Dermatophagoides pteronyssinus Suppresses the Chemotactic Activity of Human Monocytes

  • Lee, Ji-Sook;Yang, Eun Ju;Kim, In Sik
    • Biomedical Science Letters
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    • v.18 no.4
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    • pp.435-437
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    • 2012
  • House dust mite (HDM) is important in the pathogenesis of allergic diseases including asthma and atopic dermatitis. Dermatophagoides pteronissinus (Dp) is one of major HDM allergens. In this study, we investigated that Dp extract (DpE) affects on the chemotactic activity of monocytes isolated from the peripheral blood. DpE inhibited the migration of human monocytes in response to CC chemokines such as MIP-$1{\alpha}$, RANTES, HCC-4, MCP-1, and TARC. DpE did not alter the expression of CC chemokine receptors (CCRs) such as CCR1, CCR2, CCR3, CCR4, and CCR5. These results indicate that DpE blocks the chemotaxis of human monocytes and its mechanism is not involved in alteration of CCR expression. Better understanding of the effect of DpE on monocytes will enable elucidation of the role of Dp in the development of allergic diseases.

Characterization and Pathogenicity of Alternaria vanuatuensis, a New Record from Allium Plants in Korea and China

  • Li, Mei Jia;Deng, Jian Xin;Paul, Narayan Chandra;Lee, Hyang Burm;Yu, Seung Hun
    • Mycobiology
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    • v.42 no.4
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    • pp.412-415
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    • 2014
  • Alternaria from different Allium plants was characterized by multilocus sequence analysis. Based on sequences of the ${\beta}$-tubulin (BT2b), the Alternaria allergen a1 (Alt a1), and the RNA polymerase II second largest subunit (RPB2) genes and phylogenetic data analysis, isolates were divided into two groups. The two groups were identical to representative isolates of A. porri (EGS48-147) and A. vanuatuensis (EGS45-018). The conidial characteristics and pathogenicity of A. vanuatuensis also well supported the molecular characteristics. This is the first record of A. vanuatuensis E. G. Simmons & C. F. Hill from Korea and China.