• Biomolecules & Therapeutics
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• v.22 no.4
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• pp.321-327
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• 2014

Collagen pentapeptide (Lys-Thr-Thr-Lys-Ser, KTTKS) and its palmitoylated derivative (pal-KTTKS) have received a great deal of attention as cosmeceutical ingredients for their anti-wrinkle effects. The objective of this study was to evaluate stability and permeability of KTTKS and pal-KTTKS in hairless mouse skin. In this study, a liquid chromatography-tandem mass spectrometric method was developed for the quantification of pal-KTTKS, and used for stability and permeability studies. Stability studies were performed using skin extracts and homogenates. Both KTTKS and pal-KTTKS were rapidly degraded, but pal-KTTKS was more stable than KTTKS. When protease inhibitors were added, the stability of both compounds (KTTKS and pal-KTTKS) improved significantly. In the skin permeation study, neither KTTKS nor pal-KTTKS was detected in the receptor solution, which indicates that neither compound could permeate through the full-thickness hairless mouse skin in the experimental conditions of this study. While KTTKS was not detected in any of the skin layers (the stratum corneum, epidermis, and dermis), pal-KTTKS was observed in all skin layers: $4.2{\pm}0.7{\mu}g/cm^2$ in the stratum corneum, $2.8{\pm}0.5{\mu}g/cm^2$ in the epidermis, and $0.3{\pm}0.1{\mu}g/cm^2$ in the dermis. In conclusion, this study indicated that pal-KTTKS had greater stability and permeability than that of un-modified KTTKS, and may be a useful anti-wrinkle and anti-aging cosmeceutical agent.

• Journal of the Korean Ceramic Society
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• v.40 no.11
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• pp.1067-1072
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• 2003

The electrical stability of the varistor ceramics composed of Zn-Pr-Co-Cr-Dy oxides-based varistors was investigated at 0.0∼2.0 mol% Dy$_2$O$_3$ content under DC accelerated aging stress. The ceramic density was increased up to 0.5 mol% Dy$_2$O$_3$ whereas further addition of Dy$_2$O$_3$ decreased sintered ceramic density. The density sailently affected the stability due to the variation of conduction path. The nonlinearity of varistor ceramics was greatly improved above 45 in the nonlinear exponent and below nearly 1.0 ${\mu}$A by incorporating Dy$_2$O$_3$. Under 0.95 V$\_$1mA/150$^{\circ}C$/24 h stress state, the varistor ceramics doped with 0.5 mol% Dy$_2$O$_3$ exhibited the highest electrical stability, in which the variation rates of varistor voltage, nonlinear exponent, and leakage current were -0.9%, -14.4%, and +483.3%, respectively. The variation rates of relative permittivity and dissipation factor were +7.1% and +315.4%, respectively. The varistors with further addition of Dy$_2$O$_3$ exhibited very unstable state resulting in the thermal runaway due to low density.

• The Korean Journal of Food And Nutrition
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• v.8 no.2
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• pp.135-144
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• 1995

Lipid oxidation in foods produce the peroxidation products, toxic substance and rancidity odor. In vivo, lipid peroxidation by free radicals or molecular singlet oxygen cause such as a damage of DNA, cancer and aging. Accordingly, the development of new compound Inhibit lipid oxidation in foods and in vivo is very important. Antioxidants are generally used as a protection material of oxidation for a storage and preservation of foods. In terms of stability of foods and health for human, development of high effective antioxidants In a nature is required. In this point of view, this paper presents the research trends of a kind of natural antioxidative substances and its antioxidative activity.

• The Journal of Advanced Prosthodontics
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• v.14 no.5
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• pp.334-334
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• 2022

• International Journal of Automotive Technology
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• v.8 no.4
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• pp.445-453
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• 2007

This paper presents a robust controller design approach for improving vehicle dynamic roll motion performance and guaranteeing the closed-loop system stability in spite of vehicle parameter variations resulting from aging elements, loading patterns, and driving conditions, etc. The designed controller is linear parameter-varying (LPV) in terms of the time-varying parameters; its control objective is to minimise the $H_{\infty}$ performance from the steering input to the roll angle while satisfying the closed-loop pole placement constraint such that the optimal dynamic roll motion performance is achieved and robust stability is guaranteed. The sufficient conditions for designing such a controller are given as a finite number of linear matrix inequalities (LMIs). Numerical simulation using the three-degree-of-freedom (3-DOF) yaw-roll vehicle model is presented. It shows that the designed controller can effectively improve the vehicle dynamic roll angle response during J-turn or fishhook maneuver when the vehicle's forward velocity and the roll stiffness are varied significantly.

• Journal of the Korean Institute of Electrical and Electronic Material Engineers
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• v.21 no.7
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• pp.652-659
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• 2008

The nonlinear electrical properties and aging characteristics against surge stress of ZPCCL-based varistors were investigated for different sintering temperatures of the range $1240-1300^{\circ}C$. As the sintering temperature increased, the varistor voltage decreased from 732.2 to 53.8 V/mm, the nonlinear exponent decreased from 58.5 to 4.1, and the leakage current increased from $0.38{\mu}A$ to $46.5{\mu}A$. The varistors sintered at $1250^{\circ}C$ and $1260^{\circ}C$ exhibited the high stability against multiple surge, $150A/cm^2(8{\times}20{\mu}s)$. On the whole, the variation rate of electrical characteristics against impulse current stress was gradually increased in order of varistor voltage$\rightarrow$nonlinear exponent$\rightarrow$dissipation facto$\rightarrow$leakage current.

• Journal of Powder Materials
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• v.9 no.5
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• pp.336-340
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• 2002

The $\alpha$-zirconium phosphate particles as fine as 20 nm were fabricated through solution technique using $ZrOCl_2{\cdot}8H_2O$ and $H_3PO_4$ as precursors. Stability of $\alpha$-Zirconium phosphate could be ensured by adding excess phosphoric acid to a stoichiometric composition Instead of using reflux route that resulted in coarsening of particles due to an inevitably long aging. The excess phosphorous incorporated in the crystal could be successfully eliminated afterwards through careful washing. Moreover, heavily agglomerated particles are observed before washing, but fairly dispersed state is found out after washing treatment. Thus, it is found that dispersed state as well as phase stability is ensured through proper washing treatment.

• 한국정보디스플레이학회:학술대회논문집
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• 2006.08a
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• pp.998-1001
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• 2006

Highly stable organic electroluminescent devices have been achieved by treatment of thermal and electrical annealing. We investigate here the performance of theses devices at temperatures and pulse aging. We also demonstrate improved device stability due to thermal and electrical treatment, and the brightness decays at no treatment, thermal only, electrical only and thermal/electrical treatment were 86.6%, 89.5%, 93.0%, and 96.7%, respectively, in the after 150 h of operation driven with an initial luminance of $1,000\;cd/m^2$.

• The Journal of Korean Physical Therapy
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• v.11 no.2
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• pp.139-147
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• 1999

The purpose of this study was to evaluate and compare the limits of stability(LOS) data obtained from aged 20 to 69 years. In addition, this study was carried out to know correlation between age and LOS. 150 adults without neurosurgical and orthopedic disability from 20 to 69 years of age participared in this study. The LOS was measured at Two Feet Forceplate with BPM(Balance Performance Monitor) Dataprint Software Version 5.3. In this study applied the independent t-test, one-way ANOVA, and correlation analysis to determine the statistical significance of results at 0.05 level of significance. The results of this study were as follows: 1. The anteroposterior LOS significantly differented from 40 age group to 60 age group. 2. The mediolateral LOS significantly differencted from 50 age group to 60 age group. 3. There were statistically significant differences in anteroposterior LOS according to age increasing.

• Journal of Powder Materials
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• v.1 no.1
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• pp.4-14
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• 1994

The effects of Ce on the mechanical alloying behavior and the thermal stability of Al-8wt.%Fe were investigated. The steady states of Al-8wt.%Fe and Al-8wt.%Fe-4wt.%Ce powders with 1.5 wt.% stearic acid as a process control agent were reached after mechanical alloying for 1000 minuties and 1300 minuties respectively at the conditions of the impeller revolving velocity of 300 rpm and the ball to powder input ratio of 50 : 1. The hardness of Al-8wt.%Fe specimen hot extruded and isothermally aged at various temperatures for up to 1000 hours decreased rapidly at 50$0^{\circ}C$ and its high temperature ultimate tensile strength began to decrease at 40$0^{\circ}C$ with increasing aging time. The decrease in the hardness and ultimate tensile strength of the specimen were reduced substantially by addition of Ce. It was thought to be due to the formation of thermally stable A14Ce and All3Fe3Ce intermetallic compounds.