• Steel and Composite Structures
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• v.25 no.1
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• pp.93-104
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• 2017

In the present work, the effect of hygrothermal aging on the glass fibre and epoxy matrix interface has been investigated by destructive and non-destructive techniques. The glass fiber reinforced polymer (GFRP) composite laminates were prepared using Vacuum Assisted Resin Infusion Molding (VARIM) technique and the specimens were immersed in simulated seawater, followed by quantitative measurement. Besides this, the tensile tests of GFRP specimens revealed a general decrease in the properties with increasing aging time. Also, exposed specimens were characterized by a non-destructive ultrasonic guided Lamb wave propagation technique. The experimental results demonstrate a correlation between the drop in ultrasonic voltage amplitude and fall in tensile strength with increasing time of immersion. Hence, the comparison of the transmitted guided wave signal of healthy vis-a-vis specimens subjected to different extents of hygrothermal aging facilitated performance evaluation of GFRP composites.

• Journal of Industrial Convergence
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• v.18 no.1
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• pp.87-96
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• 2020

The purpose of this study was to examine the dual mediating effects of growth mindset and hope between body image and successful aging of the elderly. For this purpose, we surveyed 422 elderly people in D and S city of Chungcheongnam-do, and D metropolitan city. Collected data were analysed using SPSS 25.0 and PROCESS macro 3.4 program. Frequency analysis, reliability analysis and dual mediating effect analysis by using bootstrap were performed. The results of the study are as follows. First, as a result of correlation analysis there was a statistically significant positive correlation between variables. Second, as a result of path analysis, body image had a positive effect on growth mindset and hope, growth mindset had a positive effect on hope and successful aging, and hope also had a significant effect on successful aging. Third, as a result of dual mediation effect analysis, growth mindset and hope mediated in the relationship between body image and successful aging. This study provided new models and basic data by using body image, growth mindset and hope for successful aging of the elderly.

• Journal of the Korean Society of Food Science and Nutrition
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• v.28 no.4
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• pp.871-875
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• 1999

This study was carried out to investigate the effects of freezing temperature on the quality of thawing aged beef loin. Drip loss was higher at 3oC freezing than at 20oC freezing, showing 17.21% drip loss after 6 days aging by 3oC freezing, 14.92% drip loss 12 days aging by 20oC freezing. Cooking loss by both water bath and pan boiling were decreased with increased in aging days. The salt soluble protein extractability of the beef loin was increased until 9 days aging by both 3oC and 20oC freezing, after that was decreased. The L value of the beef loin was high until 9 days aging by 3oC freezing, after that the L value of that was decreased. And the aging at 20oC freezing was high significantly with increased aging days. The a value of the beef loin was low significantly in 6 and 9 days aging by 3oC freezing, 20oC freezing was low significantly with increased aging days. The b value of the beginning of aging was higher with increased aging days. The percentage of denatured myoglobin of the beginning of aging was the highest, then those of 3oC and 20oC freezing showed 89.70% and 88.00%, respectively. The shear force of the beef loin was decreased with aging days, but the myofibrillar fragmentation index increased with aging days. The pH of the beef loin increased until 6 days of aging by both 3oC and 20oC freezing, after that the pH decreased.

• The Korean Journal of Physiology and Pharmacology
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• v.21 no.2
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• pp.205-213
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• 2017

Quercetin, a plant-derived flavonoid found in fruits, vegetables and tea, has been known to possess bioactive properties such as anti-oxidant, anti-inflammatory and anti-cancer. In this study, anti-cancer effect of quercetin and its underlying mechanisms in triple-negative breast cancer cells was investigated. MTT assay showed that quercetin reduced breast cancer cell viability in a time and dose dependent manner. For this, quercetin not only increased cell apoptosis but also inhibited cell cycle progression. Moreover, quercetin increased FasL mRNA expression and p51, p21 and GADD45 signaling activities. We also observed that quercetin induced protein level, transcriptional activity and nuclear translocation of Foxo3a. Knockdown of Foxo3a caused significant reduction in the effect of quercetin on cell apoptosis and cell cycle arrest. In addition, treatment of JNK inhibitor (SP 600125) abolished quercetin-stimulated Foxo3a activity, suggesting JNK as a possible upstream signaling in regulation of Foxo3a activity. Knockdown of Foxo3a and inhibition of JNK activity reduced the signaling activities of p53, p21 and GADD45, triggered by quercetin. Taken together, our study suggests that quercetin induces apoptosis and cell cycle arrest via modification of Foxo3a signaling in triple-negative breast cancer cells.

• The Journal of Internal Korean Medicine
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• v.26 no.2
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• pp.379-389
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• 2005

Objectives: It is well known that aging and aging-related diseases are linked to the increased level of oxidative stress caused by reactive oxygen species(ROS) and reactive nitrogen species(RNS). Nonprotein-SH decreases during aging, while substances such as ROS, nitric oxide(NO), peroxynitrite($ONOO^-$), myeloperoxidase(MPO), and dityrosine show a significant increase. This study investigated the effect of Ichungwhan on the aging process by examining its effect on the generation of the above-mentioned substances. Methods: Four comparison groups of SD rats were used. They were 6 month-old rats, 24 month-old rats, and 24 month-old rats fed with food containing 0.1% and 0.3% of Ichungwhan extract. The amount of NO, $ONOO^-$, and ROS in the rats' kidneys were examined using a fluorescence microplate reader. The reagents used for this purpose include: dihydrorhodamine 123 (DHR 123), 2',7' -dichlorodihydrofluorescein, diacetate(DCFDA), and 4,5-diaminofluorescein(DAF-2). A spectrophotometer was used to investigate the reactivity of nonprotein-SH and myeioperoxidase(MPO), using reagents such as trichloroacetic acid(TCA) and tetramethylbenzidine(TMB). The amounts of MPO protein and dityrosine were measued by western blot. Results: The observed effects of Ichungwhan on rats were as follows: increase of nonprotein-SH; effective decrease of RNS level by suppression of the generation system of $ONOO^-$ and NO; decrease of ROS level; decrease of the MPO reactivity and the subsequent reduction of amount of MPO protein; retardation of dityrosine formation. It can be hypothesized, therefore, that Ichungwhan affects both the earlier and later phases of the molecular inflammatory process, and retards the aging process. Conclusions: Empirical evidence in this study supports a role for Ichungwhan in generation mechanisms of aging process-linked substances ROS, NO, $ONOO^-$, nonprotein-SH, MPO and dityrosine. Affects contrary to the aging process observed in rats beg further empiricism to investigate potential application of Ichungwhan as a medication for age-related diseases in humans.

• The Journal of the Korea Contents Association
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• v.16 no.4
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• pp.582-593
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• 2016

The purpose of this study was to identify predictive factors of successful aging and to determine mediating effect of transcendence between successful aging and influencing factors of community-dwelling elders in Korea. 162 elders were participated in this study who visited seniors welfare center and senior citizen center. Data were analyzed by PASW 18.0 for t-test, Pearson's correlation coefficients and hierarchical regression analysis. Transcendence, parent-child relationship, depression, spirituality and perceived economic status were statistically significant influencing factors, explained 77% of successful aging in community-dwelling elderly. The mediating role of transcendence was identified about parent-child relationship, depression, spirituality and perceived economic condition. The study findings demonstrated that transcendence was significant variable affecting successful aging. The variables affecting successful aging such as transcendence, parent-child relationship, depression, spirituality, perceived economic status can be utilized for nursing strategies to successful aging in community-dwelling elders.

• The Korean Journal of Food And Nutrition
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• v.28 no.6
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• pp.1019-1025
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• 2015

The influence of aging on the flavor precursors and volatile compounds of top round beef was studied. The concentrations of free amino acids, nucleotides, creatine, dipeptides, and volatile compounds were measured after top round from Hanwoo was aged at $4^{\circ}C$ for 21 days. The amount of free amino acids in top round significantly increased with the increase of aging period. There was no effect of aging on the concentrations of adenosine monophosphate or inosine in top round. The inosine monophosphate content of top round significantly decreased with age, while the hypoxanthine content increased. The concentrations of creatine, carnosine, and anserine in top round were not influenced by aging. In total, 24 volatile compound were identified in aged, cooked top round. Of these, the quantities of aldehydes (propanal, pentanal, hexanal, heptanal, octanal, and nonanal), hydrocarbons (pentane and octane), 2-butanone, ethyl acetate, and pyridines (4-ethynyl-pyridine and 4-acetyl-pyridine) significantly increased after aging. We conclude that the flavor of top round can be improved by aging.

• 한국노년학
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• v.38 no.3
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• pp.521-536
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• 2018

The purpose of this study is examining the effect of aging attitudes of older people on their life satisfaction, and investigating the mediating role of solidarity between parents and children. To achieve this, the survey was conducted with 2,076 Korean elderlies who were sampled with proportional stratified, and performed multi-mediated regression with SPSS macro PROCESS v.2.16. The results are following. First, aging attitude that older people recognized significantly affects to their life satisfaction. Second, aging attitude significantly affects to the five sub-categories of solidarity between parents and children. Especially, as elderly shows more negative attitude on aging, the solidarity also goes higher. Third, among sub-categories of solidarity between parents and children, affectional, identical, and functional solidarities play roles of mediator on the relationship between aging attitude and life satisfaction, and affectional solidarity shows the biggest influence on the relationship. Based on the results, practical and policy intervention were suggested for better life satisfaction of Korean elderly.

• Composites Research
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• v.22 no.6
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• pp.39-44
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• 2009

The effect of exposure times on the aging characteristics of carbon fiber/epoxy composite ring specimen was evaluated using an accelerating aging tester. Combined exposure conditions, such as temperature, moisture, and ultraviolet, were applied up to 3000 hours. Tensile properties and flexural properties including the effect of curvature were evaluated on the specimens subject to various exposure times through a material testing system. Their aging surfaces were observed through a scanning electron microscope. According to the results, tensile modulus was little affected by the exposure times. However, tensile strength, at the early stage of the exposure times, increased due to physical aging and curing reaction, but tensile strength slightly decreased due to degradation as the exposure times increased. The flexural modulus and flexural strength increased at the early stage of the exposure times, but slightly decreased as the exposure times increased. Aging surfaces of the specimens examined using the scanning electron microscope revealed a different morphology in various exposure times and provided useful information for identifying the degradation in mechanical properties of the composite subject to various exposure times.

• International Journal of Automotive Technology
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• v.7 no.3
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• pp.245-249
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• 2006

Accelerated aging of engine exhaust system components such as catalytic converters are traditionally performed using an engine/dynamometer test stand. $SwRI^{(R)}'s\;FOCAS^{(R)}$ system reduces or eliminates many of the engine based aging limitations. This paper will describe several studies. These include: 1) replication of engine based catalyst aging cycles with added precision and dependability; 2) catalyst aging with and without lubricating oil effects; 3) effects of lubricant phosphorus on catalyst performance; and 4) the potential to thermally age components beyond the capabilities of engine based systems. The first study includes the development of the SwRI FOCAS system to run programmed aging conditions with or without lubricating oil. A description of the subsystems is given. The second two studies used the SwRI FOCAS system to age catalysts. One study compared thermal-only aging using of the SwRI FOCAS system with equivalent aging on a traditional engine/dynamometer test stand. The other study examined the effect on catalyst performance of two lubricating oils containing different levels of phosphorus, and compared the results to field data generated using the same oils in a fleet of vehicles.