• Proceedings of the Korean Information Science Society Conference
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• 2011.06d
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• pp.115-117
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• 2011

Intrusion detection systems (IDS) are supposed to be an efficient safety measure against inside attacks. In purely distributed IDS approach, IDS agent is installed in every node. It checks abnormal behavior of neighboring nodes locally. It collects the data that it receives from nodes in its radio range. Sensor nodes audit that data and generate alerts for abnormal activity. Here, there are two ways of taking decision. First, it can take decision individually and second, it can communicate with its neighbor to find the status of the claimed compromised nodes. In this paper, we propose a collaborative decision making scheme for purely distributed detection system. The proposed scheme is light weight compared to consensus based validation methodology. It provides a better scheme to find intrusions by interacting with other nodes.

• Journal of Veterinary Clinics
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• v.19 no.4
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• pp.450-454
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• 2002

A five-year-old, female Great Dane dog with edema, localized trauma, mild pain, and lameness of the right hind limb was referred to the Veterinary Medical Teaching Hospital of Chungbuk National University. This dog had a history of mammary tumor excisions 6 months ago. Abnormal changes were not seen in the values of complete blood count and serum biochemical tests. But pedal direct lymphangiography using aqueous-based radiographic agent showed the obstructed lymph flow in right popliteal lymph node. Based on these observations, the dog was suspected as lymphedema resulted from lymph drainage flilure without any other possibilities of inflammation or other causes. Although recommended chemotherapy and physiotherapy had been applied for resolvinr presented problems for one month, there was no improvement on edema of damaged region and any other clinical signs. Therefore, the necropsy was performed after euthanasia under agreement of the owner of patient. In histopatholofical examination, the most characteristic lesions in the mass of femoral region were diffuse edema fibrosis and neoplastic cells in the lymphatics. Also, the neoplastic cells were very similar to those found in the tumor mass of mammary gland, which had diagnosed as fibrosing carcinoma. These facts suggested that the cause of obstructed lymph flow was the neoplasia in lymphatics of the right hind limb. With these results, a diagnosis of malignant lymphedema was made in this dog.

• Journal of Physiology & Pathology in Korean Medicine
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• v.20 no.6
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• pp.1604-1611
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• 2006

Ostreae concha is natural products of sea that haves good function for anti-stress. WE observed the effect of Otreae concha, Yukkwooltang and yukwool-tang add Ostreae concha for catecholamine, GOT, GPT, LDH and TG after immobilization stress, Ostreae concha depressed the stress response. In immunohistochemical analysis, The area of withe pulp of the spleen decreased in the control groups as compared with control ones. At same time, more severe histological changes of spleen such as the decreased diameter of periarterial lymphoid sheath and splenic node were demonstrated in the rats challenged with emotional stress. But these changes were slightly recovered in rats pretreated with Sample I, Sample II and Sample III. Immunohistochemical analysis showed that the expression of the inflammation-related protein tended to increase. But a decline of these expression, especially TNF-${\alpha}$ by pretreated with Sample I, were observed in the red pulp of spleen of the experimental rats. These results suggest that ostreae concha may act as a therapeutic agent for stress disease through a regulation of stress-related hormones.

• Parasites, Hosts and Diseases
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• v.45 no.4
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• pp.247-253
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• 2007

Leishmania (L.) tropica is a causative agent of cutaneous leishmaniasis, and occasionally of visceral or viscerotropic leishmaniasis in humans. Murine models of Leishmania infection have been proven to be useful for elucidation of mechanisms for pathogenesis and immunity in leishmaniasis. The aim of this study was to establish a murine model for human viscerotropic leishmaniasis, and the growth pattern of L. tropica was studied in different tissues of BALB/c mice in order to find out whether the parasite visceralizes in this murine model. L. major was used as a control as this species is known to cause a progressive infection in BALB/c mice. L. tropica or L. major was injected into the footpad of mice, and thickness of footpad, parasite loads in different tissues, and the weight of the spleen and lymph node were determined at different intervals. Results showed that L. tropica visceralizes to the spleen and grows there while its growth is controlled in footpad tissues. Dissemination of L. tropica to visceral organs in BALB/c mice was similar to the growth patterns of this parasite in human viscerotropic leishmaniasis. The BALB/c model of L. tropica infection may be considered as a good experimental model for human diseases.

• Applied Chemistry for Engineering
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• v.30 no.5
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• pp.513-522
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• 2019

Catalysts based on organic compounds, transition metal and metal-organic frameworks (MOFs) have been applied to degrade or remove organophosphorus toxic compounds (OPs). During the last 20 years, various MOFs were designed and synthesized to suit application purposes. MOFs with $Zr_6$ based metal node and organic linker were widely used as catalysts due to their tunability for the pore size, porosity, surface area, Lewis acidic sites, and thermal stability. In this review, effect on catalytic efficiency between MOFs properties according to the structure, stability, particle size, number of connected-ligand, organic functional group, and so on will be discussed.

• International Journal of Computer Science & Network Security
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• v.21 no.7
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• pp.341-349
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• 2021

Many emerging mobile ad-hoc network application communications are group-oriented. Multicast supports group-oriented applications efficiently, particularly in a mobile environment that has a limited bandwidth and limited power. Energy effectiveness along with safety are 2 key problem in MANET design. Within this paper, MANET is presented with a stable, energy-efficient clustering technique. In this proposed work advanced clustering in the networks with ticket ID cluster manager (TID-CMGR) has formed in MANET. The proposed routing scheme makes secure networking the shortest route possible. In this article, we propose a Cluster manager approach based on TICKET-ID to address energy consumption issues and reduce CH workload. TID-CMGR includes two mechanism including ticket ID controller, ticketing pool, route planning and other components. The CA (cluster agent) shall control and supervise the functions of nodes and inform to TID-CMGR. The CH conducts and transfers packets to the network nodes. As the CH energy level is depleted, CA elects the corresponding node with elevated energy values, and all new and old operations are simultaneously stored by CA at this time. A simulation trial for 20 to 100 nodes was performed to show the proposed scheme performance. The suggested approach is used to do experimental work using the NS- simulator. TIDCMGR is compared with TID BRM and PSO to calculate the utility of the work proposed. The assessment shows that the proposed TICKET-ID scheme achieves 90 percent more than other current systems.

• Annual Conference of KIPS
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• 2011.04a
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• pp.945-948
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• 2011

기존의 모바일 IPv6에서 경로 최적화를 하기 위해 바인딩 업데이트를 할 때 RR 프로토콜을 사용한다. IPv6에서 바인딩 업데이트는 이동노드가 홈 네트워크에서 외부 네트워크로 이동했을 때 Home Agent와 Correspondent Node(CN)에게 전송하며 이 과정에서 몇 가지 취약점으 가지고 있다. HoIT와 CoIT 메시지는 서로 연관이 없으며 이동 단말과 HA사이에만 IPSec으로 보호된 터널이 존재하고 HA와 CN 사이에는 보호되지 않는다. 따라서 공격자는 CN과 가까이에 위치하여 자신의 CoA를 CN에게 CoIT를 보내 토큰을 받아서 CN과 바인딩 업데이트를 할 수 있다. 바인딩 업데이트가 끝나면 두 노드사이는 정상적인 통신을 할 수 있고 공격자에 의해 위험에 노출 될 수 있다. 또한 CoIT 메시지를 보내면 CN에서는 토큰을 생성하게 되므로 공격자가 다수의 기기를 획득해 CN에게 계속 CoIT를 보내면 계속 토큰을 만들어야 하므로 다른 정상적인 노드의 통신을 방해할 수 있다. 따라서 이 논문에서는 이러한 RR프로토콜에 대한 문제점을 분석하고 이러한 문제점을 해결 할 수 있는 개선 방안을 논의 해본다.

• Journal of KIISE:Information Networking
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• v.30 no.4
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• pp.474-483
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• 2003

The secret sharing is the basic concept of the threshold cryptosystem and has an important position in the modern cryptography. At 1995, Jarecki proposed the proactive secret sharing to be a solution of existing the mobile adversary and also proposed the share renewal scheme for (k, n) threshold scheme. For n participants in the protocol, his method needs O($n^2$) modular exponentiation per one participant. It is very high computational cost and is not fit for the scalable cryptosystem. In this paper, we propose the efficient share renewal scheme that need only O(n) modular exponentiation per participant. And we prove our scheme is secure if less that ${\frac}\frac{1}{2}n-1$ adversaries exist and they static adversary.

• Journal of the Korea Institute of Information and Communication Engineering
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• v.12 no.11
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• pp.1966-1975
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• 2008

NEMO Basic Support Protocol standardized in IETF provides the seamless communication environment to all nodes within the mobile network regardless of the network movement while the network is moving. According to the standard, when the mobile network moves outside of its home network the network can make use of the binding update message or dynamic routing protocol in order to register the mobility information into the Home Agent(HA). But because these two methods don't consider the route optimization, all packets destined to Mobile Network Nodes(MNNs) attached into the Mobile Router(MR) have to go through HAs of MRs so that they bring on the transmission delay and the waste of the bandwidth. This situation is to be worse and causes the packet fragmentation problem if MRs within the mobile network are nested. Even though there have been some researches about the route optimization to recover the problems, they have problems in the packet transmission performance side. In this paper, we propose a new scheme to improve the network performance by using a dynamic routing protocol and minimizing the number of HAs on the end-to-end path. Various performance evaluations show that the proposed mechanism gives better performance in view of the packet transmission compared to the existing schemes.

• The Journal of Internal Korean Medicine
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• v.33 no.4
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• pp.387-404
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• 2012

Objectives : This study was to observe anticancer and related immunomodulatory effects of Kwibi-tang extracts (KBTe) on non-small cell lung carcinoma (squamous epithelial carcinoma), NCI-H520, xenograft Balb/c nu-nu nude mice. Methods : Three different dosages of KBTe, 50, 100 and 200 mg/kg were orally administered once a day for 42 days from 11 days after tumor cell inoculation. Six groups, each of 8 mice per group were used in the present study. Changes in body weight, tumor volume and weight, lymphatic organs (spleen and popliteal lymph node), serum interferon (IFN)-${\gamma}$ levels, splenocytes NK cell activity and peritoneal macrophage activities, splenic tumor necrosis factor (TNF)-${\alpha}$, interleukin (IL)-$1{\beta}$ and IL-10 contents were observed with tumor mass and lymphatic organ histopathology to detect anticancer and immunomodulatory effects. The results were compared with a potent cytotoxic anticancer agent, 5-FU (5-Fluorouracil) 30 mg/kg, intraperitoneal treatment (3-day intervals for 42 days, the optimal effective treatment regimes already confirmed). Results & Conclusions : This study suggest that over 50 mg/kg of KBTe showed favorable anticancer effects on the NCI-H520 cell xenograft with immunomodulatory effects. Although relatively lower anticancer effects were observed in KBTe 200 mg/kg treated mice as compared with 5-FU 30 mg/kg treated mice, no meaningful favorable immunomodulatory effects were observed after 5-FU treatment in the present study.