• Journal of Nutrition and Health
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• v.29 no.6
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• pp.634-641
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• 1996

In order to study the prevalence of constipation among female college students in Korean and the effect of yogurt, 3,243 students in Seoul area were surveyed by questionnaires for the status of stool evacuation and 197 students with possible constipation were sampled and fed apple yogurt II from Pasteur dairy Company for 3-weeks period. Students of constipation amounted to a high ratio of 53.4%, which consisted of 13.4% in heavy constipation (1-2 times evacuation per week) and 40.0% in mild constipation(3-4times evacuation per week) during the past one-year period. To 90 of heavy constipation and 107 of mild constipation students were fed 290ml of yogurt every morning for 3-weeks period and examined for the status of stool evacuation by subsequent after 1 weeks, 57.9% after 2 weeks and 60.4% after 3 weeks(p<0.05). The effect of improvement in stool frequency was greater in heavy group than in mild group through the 3-weeks period. The number of students who experienced the disappearance of inconvenience in evacuation after drinking the yogurt was 52.3% after 1 weeks, 72.1% after 2 weeks and 76.1% after 3 weeks. Discomfort such as stomach disorder and mild diarrhea during the drinking period was observed in 24% students and it appeared that a longer drinking period was needed stool frequency was 38.7% after 1 week and 37.6% after 1 month since discontinuing yogurt drinking. The number of students reverted to the previous habit of evacuation after discontinuing was 51.6% after 1 week and 63.5% after 1 month, which were not significantly different between heavy and mild groups(p>0.05).

• The Journal of Korean Medicine
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• v.24 no.1
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• pp.181-189
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• 2003

Background : Patient, family, society and country are badly damaged by stroke (CVA : cerebrovascular accident). To reduce sequelae and return rapidly to society, treatment in the acute stage is very important. In many studies on purgation therapy (下法) used in acute stages of stroke, the changes of blood pressure, pulse and so on before and after purgation therapy were reported. However, the changes in the human body according to the day elapsed after defecation were not reported, so study was needed to confirm such changes. Methods : Seventy-six patients were studied. We observed forty-three patients at acute stroke and thirty-three patients at convalescent stroke. To confirm the importance of regular defecation in stroke patients, we analyzed blood pressure according to the day elapsed after defecation. Results : The following result were obtained. 1. In stroke group, compared with the day after defecation, the mean blood pressure of the third day after defecation increased. It increased the most in the acute stroke group. 2. Especially in stroke and acute stroke groups, compared with the second day after defecation, the mean systolic blood pressure of the third day after defecation increased significantly. 3. In the infarction group, compared with the day after defecation, the mean blood pressure of the third day after defecation increased. It increased the most in the acute infarction group. 4. Especially, in the infarction and acute infarction groups, compared with the second day after defecation, the mean systolic blood pressure of the third day after defecation increased significantly. Conclusion : In stroke patients, regular defecation is important, so we think that purgation therapy (下法) is needed in stroke patients over the third day elapsed after defecation. We think that the bowel movement control in acute stroke patients is more important than in convalescent stroke patients.

• Environmental Analysis Health and Toxicology
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• v.22 no.1 s.56
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• pp.83-90
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• 2007

This study was investigated the effort of growth and gonadal development in olive flounder, Paralichthys olivaceus exposed to PCBs Effluent Allowance Concentration, 3.0 ppb in Korea. Total length, body weight and weight gam of fish were no significant differences between two treatments (control: T.L.-110.0 mm, T.W.-9.61 g: treatment: T.L.-112.8 mm, T.W.-9.68 g), however, weight gain of fish unexposed to PCBs wat observed to increase gradually from 100 days after hatching (30 days after treatment). In the indifferentiated gonad to the juvenile stage, the differentiation of the ovary occured at 60 days after hatching (20 days after treatment) and that of the testis occured at 70 days after hatching (30 days after treatment) in two groups. In the ovary, the oogonia and ovarian lamellar appeared 130 days after hatching (50 days after treatment). The spermatogonia and resticular lobule of the testis were observed at 130 days after hatching (50 days after treatment). Testicular cyst appeared 140 days after hatching (60 days After treatment). There was no difference on the development of ovary and testis. There was no obvious difference of sex ratios. Therefore, These results considerate that PCBs have any effect for growth and gonadal development, but a little act for early growth in olive flounder.

• Korean Journal of Veterinary Service
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• v.40 no.1
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• pp.7-14
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• 2017

The present study was undertaken to clarify the changes in hematological values of Korean indigenous goats according to age. Blood samples were collected from 16 goats (5 females and 11 males) from birth up to the age of 6 weeks and the levels of various hematological values were analyzed. The body weight was increased from 2.54 kg at birth to 6.41 kg at 6 weeks age. The erythrocytes (RBC) counts and hemoglobin (Hb) values of goats were decreased at 2 weeks after birth, and increased gradually from 4 weeks after birth. The hematocrit (Ht) values were decreased until 4 weeks after birth, and increased at 6 weeks after birth. The mean cell volume (MCV) and mean cell hemoglobin (MCH) were decreased until 6 weeks after birth. The mean cell hemoglobin concentration (MCHC) was increased slightly from 2 weeks after birth. The red cell distribution width (RDW) was increased significantly at 2 weeks after birth, and decreased from 4 weeks after birth. The platelet (PLT) counts were increased significantly from 2 weeks after birth. The mean platelet volume (MPV) was decreased at 2 weeks after birth, and increased gradually from 4 weeks after birth. The total white blood cell (WBC) counts and the mean absolute numbers of neutrophil, lymphocyte, monocyte and eosinophil were increased from 2 weeks after birth. In conclusion, the data obtained from this study may be valuable as a standard for interpreting results of hematological analyses in Korean indigenous goats.

• Maxillofacial Plastic and Reconstructive Surgery
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• v.22 no.2
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• pp.133-141
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• 2000

Purpose : The purpose of this study is to estabilish clinical guidance of microvascular anastomosis in diabetic patients. This study was performed with experimental microvascular anastomosis in streptozotocin induced diabetic rats and observed histopathologic change and endohelial healing process. Materials and Methods : 70 Sprague-Dawley rats, weighting 200 to 250grams, were used for the experiment. 35 induced diabetic rats with streptozotocin and 35 control group were selected. After end-to-end carotid artery microvascular anastomosis was done, the experimental rats were sacrificed at different time interval (1st day, 3rd day, 1st week, 2nd, 4th, 6th and 8th week) for histologic examination. Light microscope observation was used in this study. Results : 1. Histopathologic changes are nearly the same healing process in two groups. But period of tissue reaction was faster in the control than diabetic group. 2. In endotheliall healing, control group started at 1 week after and completed at 4 weeks after, but diabetic group was observed partially at 4 weeks after and complete healing was not observed still at 8 weeks after. 3. In subintimal hyperplasia, control group was observed at 6 weeks after but diabetic group was observed at 6 weeks after and partially at 8 weeks after. 4. All groups showed severe inflammatory response in the early period. This respond is decreased at 2 weeks after in control group but still remained at 8 weeks after in the diabetic group. 5. In media, inflammatory response and degeneration were observed in early period. Regeneration of smooth muscle cell was observed at 1 week after in control group but 4 weeks after in the diabetic group. Conclusions : As the results of study, it could be thought that vascular regeneration process was not failured but delayed in the diabetes. It was considered that diabetes mellitus was not absolute contraindication of microvascular anastomosis.

• Korean Journal of Pharmacognosy
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• v.14 no.1
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• pp.17-23
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• 1983

To experimentally research out the effect of 'Hagocho-San' used for liver disease on the clinical treatment of oriental medicine, I induced liver damage rats by thioacetamide and dosed the extracts orally and measured the activity rate of GOT, GPT, ALP and LDH. The following results were obtained: 1) GOT activity was more decreased in the experimental group than in the control group. Extracts from mixed decoction was more efficacious than those mixed form of the extracts after individual decoction. Extracts from decoction showed continuous significance after 48 hours on, but mixed form of extracts after individual decoction was significant only after 48 hours and 96 hours. 2) GPT activity was more decreased in the experimental group than in the control group. Extracts from mixed decoction was effective after 48 hours on but mixed form of extracts after individual decoction was significant after 48 hours and 72 hours. 3) ALP activity was more decreased in the experimental group than in the control group. Extracts from mixed decoction was more efficacious than the mixed form of extracts after individual decoction and significance was verified after 72 hours on. 4) The significance of LDH activity in the extracts from mixed decoction was revealed after 72 hours and 96 hours but mixed form of extracts after individual decoction showed significance 72 hours later. 5) From the above results, it was showed that 'Hagocho-San' extract was effective on liver disease and extracts from mixed decoction was more effective than mixed form of extracts after individual decoction.

• Korean Security Journal
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• no.2
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• pp.227-258
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• 1999

In a broad sense, ‘After-care SYSTEM’ for discharged prisoners mean legal actions of prisoners who have been released from lawful detention In its narrow sense, mean preventive protection and observation activities under regular guidance and supervision against those released from penal facilities after a certain period of detention Therefore, they should not be viewed as objects of mere concern or social work programs but preventive protection should he provided to them as part of national criminal policy After-care system is in the following two ways, The one is based on individual prisoner's request and consent, which is called 'Voluntary After-care system', The other is the one which is not based in personal request or consent but is based on obligation, which is named 'Compulsory After-care system In Korea, however no Compulsory After-care system is in practice Voluntary After-care system is to be carried out 6 method in the following by existing Probation, Parole Law. (1) offer of board and lodging (2) allowance of Traveling expense (3) allowance of occupation instrument or lending rehabilitation fund (4) training of occupation and vocational guidance (5) self-reliance support for After-care probationer (6) guidance of good deed And then to establish the society without offenders is the ideal of human beings, but criminal acts don't fade away, so in the field of the science of criminology, the importance of correctional system has become greater. The correctional idea has moved from severe punishment to educational rehabilitation for the goal of protecting both offender and security from the threat of crime in to day Some it is required that Compulsory After-care system is most important system in effective measures, and that existing Probation, Parole Law in Korea is renewed into Compulsory After-care system in the future.

• Journal of Periodontal and Implant Science
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• v.31 no.2
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• pp.465-475
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• 2001

The purpose of this study was to evaluate effect of platelet rich plasma on the treatment of Grade II furcation involvement, with and without porous resorbable calcium carbonate($Biocoral^{(R)}$)in humans by digital subtraction radiography. 15 teeth(control group) were treated with porous resorbable calcium carbonate($Biocoral^{\(R)}$), and 15 teeth(test group) were treated with porous resorbable calcium carbonate($Biocoral^{(R)}$) and Platelet Rich Plasma. The change of bone density was assessed by digital subtraction radiography in this study. The change of mineral content by as much as 5%(vol) could be perceived in the subtracted images. The change of mineral content was assessed in the method that two radiographs are put into computer program to be overlapped and the previous image is subtracted by the later one. Both groups were statistically analyzed by Wilcoxon signed Ranks Test and Mann-whitney Test using SPSS program(5% significance level). The results were as follows: 1. In test group, the radiolucency in 3 months after surgry were significantly increased than 1 month after surgery(p<0.05). 2. In test group, there were no significant difference between 1 month after surgery and 6 months after surgery(p>0.05). 3. In test group, the radiopacity in 6 months after surgery were significantly increased than 3 months after surgery(p<0.05). 4. In control group, the radiolucency in 3 months and 6 months after surgery were significantly increased than 1 month after surgery(p<0.05). 5. In control group, the radiopacity in 6 months after surgery were significantly increased than 3 months after surgery(p<0.05). 6. There were no significant difference between test group and control group at 1 month, 3 months after surgery, but radiopacity in test group were significantly increased than control group at 6 months after surgery(p<0.05). In conclusion, Platelet Rich Plasma can enhance bone density.

• Parasites, Hosts and Diseases
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• v.25 no.2
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• pp.110-122
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• 1987

The rabbits were infected with Clonorchis sinensis and were treated with praziquantel at the dose of $50{\;}mg/kg{\times}2회{\times}2$ days after 1,2,4,8 weeks and 7 months from the infection. Their livers were observed histopathologically 1, 4 and 12 weeks after treatment. The findings are summarized as below. 1. The changes of the liver in control rabbits were relatively mild until 2 weeks after infection. However, widening and thickening of bile ducts, proliferation of biliary epithelium and periductal fibrosis were moderate after 4 weeks from infection and those changes were severe after 8 weeks and 7 months. Goblet cell metaplasia was found after 8 weeks from infection. 2. The mild changes of 2-week infection group were completely recovered by 4 weeks after the treatment. In the groups of 4 or more weeks after infection, the changes of bile ducts became milder in the degree after the treatment, but were still found 12 weeks after the treatment. As the infection duration was passed, more severe changes were observed after the treatment. In this context, it is concluded that the liver changes of acute clonorchiasis in the early two weeks are reversible by treatment while chronic biliary epithelial changes are irreversible. Therefore, early treatment should be recommended as possible to minimize the remaining histopathological changes of liver in clonorchiasis.

• Korean Journal of Otorhinolaryngology-Head and Neck Surgery
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• v.61 no.12
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• pp.658-662
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• 2018

Background and Objectives The early assessment of treatment is not done for benign paroxysmal positional vertigo (BPPV) since the well-known phenomenon of fatigability after a repeated positional test can mimic successful treatment. The aim of this study is to evaluate the clinical implication of 'fatigability' after Epley maneuver and to identify the therapeutic efficacy of Epley maneuver in posterior canal BPPV (PC-BPPV). Subjects and Method This study was prospectively conducted by two dizziness clinics on 51 consecutive patients diagnosed with PC-BPPV. All patients included in the study received Epley maneuver treatment. The therapeutic results were reassessed immediately after a single trial of Epley maneuver. After 30 minutes, results were reassessed repeatedly to confirm the fatigability of diagnostic procedure immediately after treatment. If the treatment was not successful after 30 minutes, Epley maneuver was repeatedly performed until complete resolution. Results Immediately after the first maneuver, 45 of 51 (88.2%) patients had neither vertigo nor nystagmus during the positional test. All patients demonstrated complete resolution after receiving one to three Epley maneuvers on the day of diagnosis. 'Fatigability (false negative result)' was confirmed for only one case (1 of 6 patients, 16.7%), in which nystagmus was observed after 30 minutes but not identified immediately after the first Epley maneuver. Conclusion The therapeutic efficacy of Epley maneuver is very high in PC-BPPV. Considering the possibility of fatigability when reassessment is performed immediately after therapeutic maneuver, clinicians should avoid assessing the outcome immediately after treatment in patients with PC-BPPV.