• 재활복지
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• v.18 no.4
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• pp.237-255
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• 2014

Idiopathic Parkinson disease(IPD) is an neurodegenerative disease caused by the loss of dopamine cells in the substantia nigra, a region of midbrain. Its major symptoms are muscular rigidity, bradykinesia, resting tremor, and postural instability. An estimated 70~90% of patients with IPD also have hypokinetic dysarthria. Subthalamic nucleus deep brain stimulation (STN-DBS) has been reported to be successful in relieving the core motor symptoms of IPD in the advanced stages of the disease. However, data on the effects of STN-DBS on speech performance are inconsistent. A medline literature search was done to retrieve articles published from 1987 to 2012. The results were narrowed down to focus on speech performance under STN-DBS based perceptual, acoustic, and/or aerodynamic analyses. Among the 32 publications which dealt with speech performance after STN-DBS indicated improvement(42%), deterioration(29%), mixed results(26%), or no change(3%). The most favorite method was found to be based upon acoustic analysis by using a vowel prolongation and Unified Parkinson's Disease Rating Scale(UPDRS). For the purpose of verifying the effect of the STN-DBS, speech evaluation should be undertaken on all speech components such as articulation, resonance, phonation, respiration, and prosody by using a contextual speech task.

• The Journal of the Acoustical Society of Korea
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• v.37 no.6
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• pp.396-403
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• 2018

In this paper, a high-performance and low-noise centrifugal fan is developed for cooling automotive seats which provide a driver with pleasant driving environment. First, the flow characteristics of the existing fan unit was analyzed using a fan performance tester and CFD (Computational Fluid Dynamics) simulations. The analysis of the predicted flow field indicated vortex flow near the tip of fan hub and stagnation flow on the top of fan hub. Two design points are devised to reduce the vortex flow and the stagnation flow observed in the existing fan unit. First, the cut-off clearance which is the minimum distance between the fan blade and the fan housing is increased to reduce the vortex strength and, as a result, to reduce the overall sound pressure level. Second, the hub shape is more modified to eliminate the stagnation flow. The validity of proposed design is confirmed through the numerical analysis. Finally, a prototype is manufactured with a basis on the numerical analysis result and its improved flow and noise performances are confirmed through the P-Q curves measured by using the Fan Tester and the SPL (Sound Pressure Level) levels measured in the anechoic chamber.

• Particle and aerosol research
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• v.14 no.4
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• pp.135-144
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• 2018

Based on a two-year measurement data, major sources for the ambient carbonaceous aerosols at the Anmyeon Global Atmosphere Watch (GAW) station were identified by using the Positive Matrix Factorization (PMF) model. The particulate matter less than or equal to $2.5{\mu}m$ in aerodynamic diameter (PM2.5) aerosols were sampled between June 2015 to May 2017 and carbonaceous species including ~80 organic compounds were analyzed. When the number of factors was 5 or 6, the performance evaluation parameters showed the best results, With 6 factor case, the characteristics of transported factors were clearer. The 6 factors were identified with various analyses including chemical characteristics and air parcel movement analysis. The 6 factors with their relative contributions were (1) anthropogenic Secondary Organic Aerosols (SOA) (10.3%), (2) biogenic sources (24.8%), (3) local biomass burning (26.4%), (4) transported biomass burning (7.3%), (5) combustion related sources (12.0%), and (6) transported sources (19.2%). The air parcel movement analysis result and seasonal variation of the contribution of these factors also supported the identification of these factors. Thus, the Anmyeon Island GAW station has been affected by both regional and local sources for the carbonaceous aerosols.

• The Journal of the Korea institute of electronic communication sciences
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• v.16 no.3
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• pp.485-492
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• 2021

The wind turbines with a rated capacity of 50kW or less are generally considered as small class. Small wind turbines are an attractive alternative for off-grid power system and electric home appliances, both as stand-alone application and in combination with other energy technologies such as energy storage system, photovoltaic, small hydro or diesel engines. The research objective is to develop the 50kW scale wind turbine blades in ways that resemble as closely as possible with the construction and methods of utility scale turbine blade manufacturing. The mold process based on wooden form is employed to create a hollow, multi-piece, lightweight design using carbon fiber and fiberglass with an epoxy based resin. A hand layup prototyping method is developed using high density foam molds that allows short cycle time between design iterations of aerodynamic platforms. A production process of five blades is manufactured and key components of the blade are tested by IEC 61400-23 to verify the appropriateness of the design. Also, wind system with developed blades is tested by IEC 61400-12 to verify the performance characteristics. The results of blade and turbine system test showed the available design conditions for commercial operation.

• Journal of the Korean Society for Aeronautical & Space Sciences
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• v.50 no.7
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• pp.507-514
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• 2022

The EO/IR targeting pod mounted on a fighter to acquire information about tactical targets is typically mounted and operated at the bottom of the aircraft fuselage. Since the aircraft equipped with such an external attachment has complexed aerodynamic and inertial characteristics compared to the aircraft flying without an external attachment, a method of system performance analyses is required to identify development risk factors in the early stages of development and reflect them in the design. In this study, a development plan was presented to provide the necessary modeling and simulation tools to develop a pod that can acquire measurement data stably in a highly maneuverable environment. The limiting operating conditions of the pods mounted on the highly maneuverable aircraft were derived, the aerodynamics and inertial loads of the mounted pods were analyzed according to the limiting operating conditions, and a flight data generation and transmission system were developed by simulating the mission of the aircraft equipped with the mounted pods.

• Journal of the Korean Society of Marine Environment & Safety
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• v.28 no.4
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• pp.648-656
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• 2022

As environmental regulations such as the International Maritime Organization (IMO)'s strategy to reduce greenhouse gases(GHG) are strengthened, technology development such as eco-friendly ships and alternative fuels is expanding. As part of this, ship propulsion technology using energy reduction and wind propulsion technology is emerging, especially in shipping companies and shipbuilders. By securing wind propulsion technology and introducing empirical research into shipbuilding and shipping, a high value-added market using eco-friendly technology can be created. Moreover, by reducing the fuel consumption rate of operating ships, GHG can be reduced by 6-8%. Rotor Sail (RS) technology is to generate a hydrodynamic lift in the vertical direction of the cylinder when the circular cylinder rotates at a constant speed and passes through the fluid. This is called the Magnus effect, and this study attempted to propose a plan to increase propulsion efficiency through a numerical analysis study on turbulence flow characteristics around RS, a wind power assistance propulsion system installed on a ship. Therefore, C_L and C_D values according to SR and AR changes were derived as parameters that affect the aerodynamic force of the RS, and the flow characteristics around the rotor sail were compared according to EP application.

• Journal of the Korean Society of Marine Environment & Safety
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• v.27 no.7
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• pp.1059-1066
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• 2021

In Korea, the importance of marine activities is great, and automatic weather observation facilities are operating on land to investigate abnormal weather phenomena caused by industrialization; however, the number of facilities at sea is insufficient. Marine survey ships are operated to establish marine safety information, but there are many places where marine survey ships are difficult to access and operating costs are high. Therefore, a small, unmanned vessel capable of marine surveys must be developed. The sail has a significant impact on the sailing performance, so much research has been conducted. In this study, the camber effect, which is a design variable of the twin curvy sail known to have higher aerodynamic performance than existing airfoil shapes, was investigated. Flow analysis results for five cases with different camber sizes show that the lift coefficient is highest when the camber size is 9%. Curvy twin sails had the highest lift coefficient at an angle of attack of 23° because of the interaction of the port and starboard sails. The port sail had the highest lift coef icient at an angle of attack of 20°, and the starboard sail had the lowest lift coef icient at an angle of attack of 15°. In addition, the curvy twin sail had a higher lift coefficient than NACA 0018 at all angles of attack.

• The Journal of the Acoustical Society of Korea
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• v.42 no.1
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• pp.7-15
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• 2023

Recently, as interest in air quality in vehicles increases, the use of fine dust detection sensors for air quality measurement is becoming common. An axial-flow fan is inserted in the fine dust sensor installed in the air conditioning system in the vehicle to prevent dust from sinking directly on the sensor. When the sensor operates, the flow noise caused by the rotation of the axial-flow fan acts as a major noise source of the fine dust sensor. flow noise is recognized as one of the product competitiveness of fine dust sensors. In this study, the noise was gradually reduced at the same flow rate by improving the flow performance of the small axial flow fan. First, a virtual fan performance tester consisting of about 20 million grids was developed to analyze the aerodynamic performance of the target small axial-flow fan. In addition, the flow field was simulated by using compressible Large Eddy Simulation for direct computation of flow noise as well as high-accurate prediction of flow rate. The validity of numerical method are confirmed through the comparison of predicted results with experimental ones. After the effects of pitch angle on flow performance were analyzed using the verified numerical method, the pitch angle was determined to maximize the flow rate. It was found that the flow rate was increased by 8.1 % and noise was reduced by 0.8 dBA when the axial-flow fan with the optimum pitch angle was used.

• Journal of Ginseng Research
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• v.47 no.1
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• pp.81-88
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• 2023

Background: Air pollution has led to an increased exposure of all living organisms to fine dust. Therefore, research efforts are being made to devise preventive and therapeutic remedies against fine dust-induced chronic diseases. Methods: Research of the respiratory protective effects of KRG extract in a particulate matter (PM; aerodynamic diameter of <4 ㎛) plus diesel exhaust particle (DEP) (PM4+D)-induced airway inflammation model. Nitric oxide production, expression of pro-inflammatory mediators and cytokines, and IRAK-1, TAK-1, and MAPK pathways were examined in PM4-stimulated MH-S cells. BALB/c mice exposed to PM4+D mixture by intranasal tracheal injection three times a day for 12 days at 3 day intervals and KRGE were administered orally for 12 days. Histological of lung and trachea, and immune cell subtype analyses were performed. Expression of pro-inflammatory mediators and cytokines in bronchoalveolar lavage fluid (BALF) and lung were measured. Immunohistofluorescence staining for IRAK-1 localization in lung were also evaluated. Results: KRGE inhibited the production of nitric oxide, the expression of pro-inflammatory mediators and cytokines, and expression and phosphorylation of all downstream factors of NF-κB, including IRAK-1 and MAPK/AP1 pathway in PM4-stimulated MH-S cells. KRGE suppressed inflammatory cell infiltration and number of immune cells, histopathologic damage, and inflammatory symptoms in the BALF and lungs induced by PM4+D; these included increased alveolar wall thickness, accumulation of collagen fibers, and TNF-α, MIP2, CXCL-1, IL-1α, and IL-17 cytokine release. Moreover, PM4 participates induce alveolar macrophage death and interleukin-1α release by associating with IRAK-1 localization was also potently inhibited by KRGE in the lungs of PM4+D-induced airway inflammation model. KRGE suppresses airway inflammatory responses, including granulocyte infiltration into the airway, by regulating the expression of chemokines and inflammatory cytokines via inhibition of IRAK-1 and MAPK pathway. Conclusion: Our results indicate the potential of KRGE to serve as an effective therapeutic agent against airway inflammation and respiratory diseases.

• Journal of the Korean Society of Laryngology, Phoniatrics and Logopedics
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• v.33 no.3
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• pp.166-171
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• 2022

Background and Objectives Vocal fold (VF) scar is known to be the most common cause of dysphonia after laryngeal microsurgery (LMS). Steroids reduce postoperative scar formation by inhibiting inflammation and collagen deposition. However, the clinical evidence of whether steroids are helpful in reducing VF scar formation after LMS is still lacking. The purpose of this study is to determine whether intralesional VF steroid injection after LMS helps to reduce postoperative scar formation and voice quality. Materials and Method This study was conducted on 80 patients who underwent LMS for VF polyp, Reinke's edema, and leukoplakia. Among them, 40 patients who underwent VF steroid injection after LMS were set as the injection group, and patients who had similar sex, age, and lesion size and who underwent LMS alone were set as the control group. In each group, stroboscopy, multi-dimensional voice program, Aerophone II, and voice handicap index (VHI) were performed before and 1 month after surgery, and the results were statistically analyzed. Results There were no statistically significant differences in the distribution of sex, age, symptom duration, occupation and smoking status between each group. Both groups consisted of VF polyp (n=21), Reinke's edema (n=11), and leukoplakia (n=9). On stroboscopy, the lesion disappeared after surgery, and the amplitude and mucosal wave were symmetrical on both sides of the VFs in all patients. Acoustic parameters and VHI significantly improved after surgery in all patients. However, there was no significant difference between the injection and control group in most of the results. Conclusion There was no significant difference in the results of stroboscopy, acoustic, aerodynamic, and subjective evaluation before and after surgery in the injection group and the control group.