• Archives of Pharmacal Research
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• v.28 no.7
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• pp.791-798
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• 2005

The hepatoprotective activity of flavonol glycosides rich fraction (F-2), prepared from 70% alcohol extract of the aerial parts of V calcarata Desf., was evaluated in a rat model with a liver injury induced by daily oral administration of $CCl_4$ (100 mg/kg, b.w) for four weeks. Treatment of the animals with F-2 using a dose of (25 mg/kg, b.w) during the induction of hepatic damage by $CCl_4$ significantly reduced the indices of liver injuries. The hepatoprotective effects of F-2 significantly reduced the elevated levels of the following serum enzymes: alanine aminotransferase (ALT), aspartate aminotransferase (AST), alkaline phosphatase (ALP) and lactate dehydrogenase (LDH). The antioxidant activity of F-2 markedly ameliorated the antioxidant parameters including glutathione (GSH) content, glutathione peroxidase (GSH-Px), superoxide dismutase (SOD), plasma catalase (CAT) and packed erythrocytes glucose-6-phosphate dehydrogenase (G6PDH) to be comparable with normal control levels. In addition, it normalized liver malondialdehyde (MDA) levels and creatinine concentration. Chromatographic purification of F-2 resulted in the isolation of two flavonol glycosides that rarely occur in the plant kingdom, identified as quercetin-3,5-di-O-$\beta$-D-diglucoside (5) and kaempferol-3,5-di-O-$\beta$-D-diglucoside (4) in addition to the three known compounds identified as quercetin-3-O-$\alpha$-L-rhamnosyl- (${\rightarrow}6$)-$\beta$-D-glucoside [rutin, 3], quercetin-3-O-$\beta$-D-glucoside [isoquercitrin, 2] and kaempferol-3-O-$\beta$-D-glucoside [astragalin, 1]. These compounds were identified based on interpretation of their physical, chemical, and spectral data. Moreover, the spectrophotometric estimation of the flavonoids content revealed that the aerial parts of the plant contain an appreciable amount of flavonoids (0.89%) calculated as rutin. The data obtained from this study revealed that the flavonol glycosides of F-2 protect the rat liver from hepatic damage induced by $CCl_4$ through inhibition of lipid peroxidation caused by $CCl_4$ reactive free radicals.

• Journal of the Korean Society of Surveying, Geodesy, Photogrammetry and Cartography
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• v.38 no.3
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• pp.223-235
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• 2020

In this study, we propose an approach for calibrating the elevation of a DEM (Digital Elevation Model), one of the key data in realizing unmanned aerial vehicle image-based precision agriculture. First of all, radiometric correction is performed on the orthophoto, and then ExG (Excess Green) is generated. The non-vegetation area is extracted based on the threshold value estimated by applying the Otsu method to ExG. Subsequently, the elevation of the DEM corresponding to the location of the non-vegetation area is extracted as EIFs (Elevation Invariant Features), which is data for elevation correction. The normalized Z-score is estimated based on the difference between the extracted EIFs to eliminate the outliers. Then, by constructing a linear regression model and correcting the elevation of the DEM, high-quality DEM is produced without GCPs (Ground Control Points). To verify the proposed method using a total of 10 DEMs, the maximum/minimum value, average/standard deviation before and after elevation correction were compared and analyzed. In addition, as a result of estimating the RMSE (Root Mean Square Error) by selecting the checkpoints, an average RMSE was derivsed as 0.35m. Comprehensively, it was confirmed that a high-quality DEM could be produced without GCPs.

• Korean Journal of Weed Science
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• v.31 no.4
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• pp.375-383
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• 2011

This experiment was carried out to confirm characteristics of macro granule (GG) for herbicidal efficacy by using remote-controlled aerial application (RCAA) to control annual and perennial weeds in rice paddy field, and phytotoxicity to rice and non target plants of formulation types. Herbicidal efficacy of GG applied by using RCAA was 93.6~96.6% in flooded direct sowing cultivation. There was no difference in phytotoxicity between the hand and the power applicator methods in terms of height, number of tiller and yield component. Herbicidal efficacy of GG applied by using RCAA was 92.7~97.3% in machine transplanting rice field. There was no difference in phytotoxicity between the hand and RCAA methods in terms of height, number of tiller and yield component. When suspension concentrate (SC) and GG were applied directly on Chinese cabbage, lettuce, cucumber, pepper, soybean and wild sesame, several symptoms of injury such as, the inhibition of growth, yellowish, leaf fall and withering was observed.

• The Korea Journal of Herbology
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• v.37 no.5
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• pp.89-96
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• 2022

Objectives : This research was performed to analyze the components in the different parts of Lythrum salicaria L. and to compare which parts of L. salicaria L. are appropriate for food development. Methods : L. salicaria L. was extracted in 20% EtOH at 100 ℃ for 4 hours. Cytotoxicity was investigated in 3T3-L1 cells after treatment of 10-500 ㎍/ml L. salicaria L. for 24 hours. Total polyphenol content (TPC) was estimated using 1 N Folin-ciocateu reagent. 2,2-Diphenyl-1-picryhydrazyl (DPPH) radical scavenging activity was estimated using DPPH reagent and gallic acid. The chemical composition was analyzed by high-performance liquid chromatography (HPLC). 1) Results : The half maximal inhibitory concentration (IC50) in the extracts of the whole plant, aerial parts, and root parts was 350 ㎍/ml, over 500 ㎍/ml, and 150 ㎍/ml, respectively. The TPC in the extracts of the whole plant, aerial parts, and root parts was 527.1 mg/g, 422.6 mg/g, and 781.1 mg/g, respectively. The averages of vitexin contents in the aerial parts, and root parts were 256.7 ± 154.9 ㎍/g and 266.1 ± 63.2 ㎍/g, respectively. The averages of TPC in the leaves, roots, flower stalks and stems were 224.0 ± 53.7 tannin acid (TA) mg/g, 221.8 ± 70.2 TA mg/g, 249.8 ± 34.4 TA mg/g, and 67.7±8.9 TA mg/g, respectively. The averages of DPPH radical scavenging activity in the leaves, roots, flower stalks, and stems were 282.01 ± 43.3 gallic acid equivalent (GAE) 𝜇mole/g, 260.16 ± 44.1 GAE 𝜇mole/g, 288.0 ± 9.3 GAE 𝜇mole/g, and 97.6 ± 10.7 GAE 𝜇mole/g, respectively. Conclusions : There were no significant differences in the content of components or antioxidant activity in the aerial parts compared to those in the whole plant of L. salicaria L. Furthermore, the root parts had low extract yield, cytotoxicity, and quality control problems, therefore our results suggest that the use of the aerial part of L. salicaria L. would be the most appropriate for food development.

• Transactions of the Korean Society of Mechanical Engineers A
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• v.39 no.5
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• pp.517-526
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• 2015

This paper presents the results of study for improving the reliability of quadrotor attitude control by applying a multi-sensor along with a data fusion algorithm. First, a mathematical model of the quadrotor dynamics was developed. Then, using the quadrotor mathematical model, simulations were performed using the improved reliability multi-sensor data as the inputs. From the simulation results, we designed a Gimbal-equipped quadrotor system. With the quadrotor in a hover state, we performed experiments according to the angle change of the user's specifications. We then calculated the attitude control data from the actual experimental data. Furthermore, with additional simulations, we verified the performance of the designed quadrotor attitude control system with multiple sensors.

• Journal of the Korean Society for Aeronautical & Space Sciences
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• v.45 no.9
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• pp.711-723
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• 2017

This paper proposes a flight control system for an organic flight array(OFA) which has a new configuration to consist of multi modularized ducted-fan unmanned aerial vehicles (UAVs). The OFA is able to apply to various missions such as indoor reconnaissance, communication relay, and radar jamming by using capability of hover flight. The OFA has a distinguished advantage due to reconfigurable structure to assemble or separate with respect to its missions or operational conditions. A dynamic modelling of the OFA is derived based on equations of motion of the single ducted-fan modules. In order to apply nonlinear control method, an affine system of attitude dynamics is derived. Moreover, the control system is composed of a back-stepping controller for attitude control and a PID controller for position control. Then the performance of the proposed controller is verified via a numerical simulation under wind disturbance.

• Journal of Korea Spatial Information System Society
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• v.11 no.3
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• pp.79-84
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• 2009

As a surveying standard of a nation, the Korean geodetic control points such as triangulation points and benchmarks require continuous and effective management toward a spatially enabled society. As the developments of information technologies, use of mobile devices like PDA (personal digital assistant) has been increasing and the Web 2.0 environment became an important part of GIS. In this context, the management systems for national geodetic control points should be upgraded in accordance with the current trend, particularly for more interactive user-interface on the Web 2.0. This paper describes the framework design and prototype implementation of a Web 2.0 GIS application for the management of Korean geodetic control points. Our system enables a real-time update of the control point information and provides aerial photos on vector maps using Ajax(Asynchronous JavaScript and XML) techniques.

• Asia-pacific Journal of Multimedia Services Convergent with Art, Humanities, and Sociology
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• v.6 no.9
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• pp.81-90
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• 2016

Recently drones have become popular enough to be one of the hobby. The drone refers to an unmanned aerial vehicle which can fly and be steered by a radio wave without a pilot and it has a airplane or helicopter shape. The drone was first started to be used from military purpose, but its usage has been expanded to the private such as construction site, crop-dusting, field discovery, freight shipping and drones to prevent cheating. However the drone that we can see often in the market is expansive, hard to be repaired when it broken down and has a discomfort of the short flight time. In this paper, to solve an uncomfortable talk on the cheap 8-bits microcontrollers ATmega128 Using drone for implementation. Axes gyroscope and accelerometers mcu between posture an attitude control, communications through drone control, pid. Receiver input them into transmitter signals of movements to control drone c the programming was implemented in on the basis of language. drone using ATmega128 microcontroller is possible hovering, By utilizing a pin that are not required for control it can be used as a drone for a variety of uses.

• Archives of Pharmacal Research
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• v.21 no.6
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• pp.718-722
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• 1998

Scopoletin (7-hydroxy-6-methoxycoumarin), a coumarin, was isolated from the aerial part of Solanum lyratum Thunb. by the activity-guided fractionation employing carbon te trachloride-intoxicated primary cultured rat hepatocytes as a screening system. Its hepatoprotective activity was first evaluated by measuring the release of glutamic pyruvic transaminase and sorbitol dehydrogenase from carbon tetrachloride-intoxicated rat hepatocytes into the culture medium. Scopoletin significantly reduced the releases of glutamic pyruvic transaminase and sorbitol dehydrogenase from the carbon tetrachloride-intoxicated primary cultured rat hepatocytes by 53% and 58%, respectively, from the toxicity in a dose-dependent manner over concentration ranges of 1mcM to 50mcM. Further studies revealed that at the concentration of 10mcM, scopoletin significantly preserved glutathione content by 50% and the activity of superoxide dismutase by 36% and also inhibited the production of malondialdehyde to the degree as seen in the control.

• KOREAN JOURNAL OF CROP SCIENCE
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• v.53 no.spc
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• pp.121-123
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• 2008

In order to verify the efficacy of Lespedeza cuneata G. Don which have been used as a folk traditional herb medicine from ancient times, the test of antioxidant activity and the analysis of constituents were carried out. Methanol extracts from L. cuneata G. Don showed a radical scavenging activity corresponding to that of (+)-catechin as positive control at 250 ${\mu}g$/mL (ca 90% inhibition), and inhibited more than 30% of DPPH radical at low concentration of 10${\mu}g$/mL. In the present study, as a fundamental study for the specification of antioxidant components from L. cuneata G. Don, the analysis for constituents for L. cuneata with HPLC was preformed although there was no results to identify functional flavonoids such as quercetin.