• Title/Summary/Keyword: adverse effect

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과체중인 소아에 있어서 아이라진 복용의 효과 (Effects of I-razin in Overweight Children)

  • 조유정;김은주;양유정;송미연
    • 한방비만학회지
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    • 제10권2호
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    • pp.17-25
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    • 2010
  • Objectives This study was performed to figure out the effects of I-razin in overweight children without any exercise or specific diet. Methods Twenty-eight children those who were diagnosed overweight have been recruited. They were randomly assigned treatment or control group under block randomization. Treatment group were treated with I-razin for 8 weeks, and control group were treated with placebo medication under same conditions. Anthropometry, fat computed tomography and blood test have been done before and after the treatment. Results Eleven subjects in treatment group and seventeen in control group were evaluated. BMI, waist circumference, glucose, total cholesterol, and triglyceride were decreased in the treatment group. And reduction of BMI, glucose, and triglyceride in the treatment group were greater than control group. But there was no statistically significance. No side effects have been notice during the study period and no adverse effect on liver has been observed. Conclusion This study could not demonstrate effect of I-razin compared with control group. However, treatment group has a tendency of weight loss without side effect. Additional studies with large population are thought to be necessary to clarify the effect of I-razin.

Effect of Country Distance on E-commerce Export: Focusing on the Moderating Effect of Entrepreneurship

  • Wang, Yi Chen;Lee, Tae Hee;Bae, Moon Gyu;Lee, Keon Hee
    • Journal of Korea Trade
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    • 제25권4호
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    • pp.60-87
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    • 2021
  • Purpose - This study examines the role of e-commerce resulting from technological innovation as a new approach toward internationalization. We study the relationship between e-commerce export and country distance, measured in CAGE distance, which has hindered traditional internationalization. As a control variable, entrepreneurship was introduced to check the moderating effect on the relationship between country distance and e-commerce export. Design/methodology - Based on empirical analysis, e-commerce exports from the Republic of Korea to 96 countries were used as dependent variables. First, hierarchical regression analysis was conducted to test the hypothesis about each country's distance, measured by CAGE distance, and each dimension of CAGE, on e-commerce exports. Next, the hypothesis was tested through the interaction term to examine the moderating effect of entrepreneurship. Findings - The analysis showed that the hypothesis, which postulated e-commerce exports as affected negatively by the country's distance, was supported but not that all CAGE dimensions affected it. Specifically, geographical distance and economic distance have negative effects, but cultural distance and administrative distance did not affect e-commerce exports. Thus, in contrast to the expectation that distance restrictions in e-commerce would not exist, this study confirmed that distance still matters to internationalization and that entrepreneurship can mitigate the adverse effects. Originality/value - Through these results, when export firms try to enter new markets and start internationalization through e-commerce, the entrepreneurship of the importing country should be considered.

A Longitudinal Investigation of the Moderating Effect of Social Support on Job Strain Developing Non-Specific Neck Pain in Office Workers

  • Jun, Deokhoon
    • The Journal of Korean Physical Therapy
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    • 제31권4호
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    • pp.254-259
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    • 2019
  • Purpose: This study examined the interactions between the job strain and social support in the workplace on the development of workrelated neck pain in office workers. Methods: The participants included 62 office workers without neck pain over the last twelve months. A battery of measures evaluating the potential workplace risk factors in office settings were conducted at the baseline, and at the 12 month incidence of work-related neck pain was reported via monthly questionnaires. Survival analysis evaluated the interaction effect between job strain and social support on the development of work-related neck pain. Results: The incidence of work-related neck pain was 1.91 (95% CI: 1.06 - 3.45) per 100 person months. The interaction effect between job strain and social support found that job strain may increase the risk of developing new work-related neck pain when lower social support existed in the workplace. On the other hand, the adverse effects of job strain on the development of neck pain were not significant when workers had higher social support from their colleagues and supervisors. Conclusion: An investigation of the moderating effects of risk factors on neck pain might reveal the unexplained relationship between the risk factors for the development of neck pain in office workers. Therefore, the interest in prevention plans and treatments should involve a comprehensive understanding of the risk factors at workplace.

Effect of Sharbat Afsantīn in Poly Cystic Ovarian Disease - An Open Observational Study

  • Zubair, Zainab;Shameem, Ismath;Begum, Wajeeha
    • 셀메드
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    • 제12권3호
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    • pp.10.1-10.12
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    • 2022
  • Objective: The objective of the study was to evaluate the effect of Sharbat Afsantin in Polycystic Ovarian Disease. Methods: An open observational study was carried out in the Department of Ilmul Qabalat wa Amraze Niswan. Diagnosed cases(n=30) of PCOD were included in the study. Patients with thyroid dysfunction, systemic diseases, on hormonal treatment in last three months, pregnancy and lactation were excluded. Research drug (Sharbat Afsantin) was administered orally in a dose of 25ml twice daily for 15 days/cycle for three consecutive cycles. Outcome measures were, changes in subjective parameters (duration of cycle, duration and amount of flow and weight reduction) and objective parameters {pictorial blood loss assessment chart (PBAC) score, basal metabolic index (BMI), modified Ferriman Gallwey (mFG) score, acanthosis nigricans scale and pelvic ultrasonography}. Data were analyzed using paired Student 't' test. Results: Changes in duration of cycle, duration and amount of flow were achieved in 83.3%, 50% and 40% patients respectively and weight reduction in 30% patients. Changes in PBAC score and BMI were achieved in 50% and 30% patients respectively and 30% patients showed normal findings on pelvic ultrasonography. Conclusion: Sharbat Afsantin can be used as an alternate remedy in PCOD patients, as it has significant effect to regularize menstruation by reduction in BMI and probably by improving insulin resistance in PCOD. No adverse effect of Sharbat Afsantin was noted during the trial.

민간의료보험 가입이 의료이용에 미치는 영향 (Effects of Private Insurance on Medical Expenditure)

  • 윤희숙
    • KDI Journal of Economic Policy
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    • 제30권2호
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    • pp.99-128
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    • 2008
  • 민간보험은 공적보험과 보완적인 관계를 형성함에도 불구하고 우리나라의 민간보험은 소득계층에 따른 접근성 차이로 인한 사회적 불평등, 도덕적 해이로 인한 공적보험 재정악화 등의 우려를 낳고 있다. 그러나 이에 관한 실증적 분석은 그간 이루어지지 못하여 정책적인 방향을 정립하는 데 장애가 되어 왔다. 본 연구는 건강보험공단, 심사평가원, 민간보험사, 행정자치부 주민등록세대정보 등의 관련 정보를 종합하여 이에 대한 실증분석을 시도했다. 그 결과, 우리나라의 민간보험 가입률은 전 국민의 64%에 달하고 있으며, 고소득층과 저소득층 간에 민간보험 가입률의 차이가 나타나지 않았다. 이는 공적보험의 보장성이 미흡한 상황에서 저소득층 역시 갑작스런 의료지출에 대비하고 있으며, 민간보험이 의료접근성의 계층화를 초래하지 않고 있다는 것을 시사한다. 또한 민간보험 가입자는 평균적으로 미가입자에 비해 의료이용량이 높지 않았으며, Two-Part Model을 통해 다양한 변수를 통제했을 경우에도 동일한 결과가 나타났다. 연령대에 따른 차이로 미루어 이러한 결과는 노동시장과 연관된 한시적인 성격일 것으로 추측되나, 현재로서는 민간보험 가입에 따른 도덕적 해이가 강하게 나타나고 있다는 근거는 발견되지 않았다.

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사망 전 노인들의 보완대체요법 이용수준 및 관련 요인 (Utilization Level and Associated Factors of Complementary and Alternative Medicine in the Older Population before Death)

  • 조남홍;우은경;이지전;이상욱;조항석;김선현
    • Journal of Hospice and Palliative Care
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    • 제7권1호
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    • pp.37-48
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    • 2004
  • 목적: 보완대체요법을 이용하는 인구 및 비용이 전 세계적으로 꾸준히 늘고 있다. 젊은 인구에 비해 노인인구에서 이용량이 높을 것으로 생각된다. 본 연구에서는 노인사망자를 대상으로 사망전 6개월간의 보완대체요법 이용실태를 조사하고자 했다. 방법: 2001년 하반기동안 사망한 후 건강보험에서 장제비를 지급 받은 서울지역 65세 이상 노인 4210명을 선정하였다. 이들을 성별 연령별로 배열하여 14명씩 총 301군으로 구분하였고, 각 군에서 1명씩 선택하여(총 301명) 사망시 연령, 성별, 사망 원인질환, 보완대체요법에 대한 설문조사를 시행하였다. 보완대체요법은 심신조정요법, 한의학 관련요법, 한방민간요법, 식이 영양 요법, 수기신체 치료 요법, 약물요법, 에너지 요법으로 총 7가지 영역으로 구분하였다. 결과: 사망 전 6개월간 보완대체요법을 이용한 사망자는 247명으로 전체 대상자의 83.1%였다. 보완대체요법중 특히 식이 영양 요법의 이용률(65.5%)이 가장 높았고 약물요법(29.9%)도 많이 이용하였다. 성별과 사망원인에 따라 이용률에 유의한 차이를 보였는데 여성(60%)이 남성(40%)보다 높았고, 노인성 질환군(30.8%)이 가장 높고, 암인 군(16.8%)이 가장 낮았다. 보완대체요법의 전체 만족도와 부작용 점수를 보면 6점 만점에 평균 4.25점, 부작용은 평균 5.55점으로 부작용이 거의 없었다. 식이 영양요법의 만족도(평균4.41점)가 가장 높았고 수기신체치료요법(평균 3.38점)이 가장 낮았다. 수기신체치료요법에서 부작용이 가장 없었고(평균 5.88점), 한의학 관련요법의 부작용 점수가 가장 낮았다(평균 5.35점). 또한 연령과 사망원인 질병에 따라 만족도와 부작용 수준에 유의한 차이를 보였다. 결론: 65세 이상 노인의 대다수가 사망전 6개월간 보완대체요법을 이용하였으며 전체 만족도도 상당히 높고 부작용도 거의 없었다. 현실적인 대안을 마련하는 것이 필요하다.0.04{\pm}0.20$ P=0.1519), 우울 정도, 불안 정도, 스트레스 정도는 자가치료 순응도가 좋을수록 감소하는 경향을 보였으나, 통계적으로 유의하지는 않았다. 아로마 자가 치료군에서 수축기 혈압은 약간 증가하였으나 통계학적 의의는 없었다($4.53{\pm}14.43mmHg\;vs\;0.0{\pm}7.22mmHg$, P=0.152). 자가 치료군에서 환자들은 두통(20%), 감각이상(6.7%), 오심(6.7%) 등의 부작용을 호소했으나, 이들 모두 일시적인 것으로 자가치료를 중단할 정도는 아니었다. 결론: 유방암 환자들에게 아로마 손 마사지 교육을 시킨 후 자기 스스로 2주간 시행한 결과, 통증강도, 우울 및 불안 정도가 의미 있게 감소하였다.임의 유무와 이유에 대해서는, '망설이지 않았다'(34명)가 '망설였다'(6명)보다 높게 나타났다. 사별가족모임에 참석한 후의 소감, 개선사항, 아쉬운 점에 대한 질문에는, 대부분의 응답자들이 '의미 있는 시간이었다', '사별가족에 대한 배려와 관심에 대해 감사한다.'라는 긍정적인 응답이 있었고, '고인에 대한 회상을 할 수 있는 자리여서 좋았다.' '사별가족모임이 일년에 한 번이 아니라 계속적으로 있었으면 한다.', '한편은 슬프고 한편은 기쁘다.' 등의 의견이 있었다. 사별 후 느끼는 가장 큰 어려움에 대해 참석가족은, '우울감'(10명), '외로움'(7명)의 빈도가 높았고, '그리움'(1명), '경제적/역할상 어려움'(4명), 무응답(6명)으로, '우울감'이 가장 큰 어려움으로 나타났다. 반면에, 비참석 가족에서는, 가장 큰 어려움은 '경제적/역할상 어려움'(6명), '외로움'(5명), '우울감'(3명), '후회감'(1명), '고인에 대한 원망감'(1명), '특별히 어려움이 없다'(1명)라고 답하였다. 결론: 호스피스 서비스를

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혐기성 연속 회분식 공정에 의한 도시하수슬러지 소화시 고액분리 특성에 따른 처리효율평가 (Performances of Anaerobic Sequencing Batch Reactor for Digestion of Municipal Sludge at the Conditions of Critical Solid-liquid Separation)

  • Hur, Joon-Moo;Park, Jong-An
    • 한국환경보건학회지
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    • 제28권5호
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    • pp.77-85
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    • 2002
  • 중온과 고온의 혐기성 연속회분식 공정(anaerobic sequencing batch reactor ; ASBR)에서 소화슬러지의 고액분리특성이 처리효율에 미치는 영향을 규명하고자 하였다. 연구결과 침전가능 고형물농도가 높은 도시하수슬러지 처리시 고액분리특성 및 고액분리형태가 전체처리의 안정성 및 처리효율에 상당한 영향을 미쳤다. 중온ASBR에서는 부상농축현상이 일어났으나, 고온ASBR에서는 중력농축에 의한 고액분리가 일어났으며, 상대적으로 고온 ASBR의 처리효율이 우수하였다. 그리고 수리학적 체류시간, cycle period 및 고액분리형태는 소화슬러지의 농축 특성과 임계 고형물농축을 지배하는 중요한 인자였다. 중온ASBR에서 고액분리 후 농축슬러지베드용적(thickened sludge bed volume)은 매우 중요한 운전 요소이며, 소화슬러지의 중력농축특성은 배출시 농축고형물의 유실현상과 침전시 계속적으로 발생하는 소화가스에 의한 슬러지계면의 파괴현상 및 슬러지베드의 불안전성을 야기시켜 처리효율을 감소시켰다. 중력농축의 경우 소화가스와 슬러지농축용적간의 상호작용(cyclic mutual effect)이 주기적으로 일어났으나, 부상농축에서는 이러한 현상이 일어나지 않았다.

친환경농산물 선택기준이 구매의도에 미치는 영향 : 소비자 태도와 신뢰의 매개, 조절효과를 중심으로 (Effects of Selection Criteria for Eco-Friendly Agricultural Products on Purchase Intention)

  • 김미송;김동환;이기황;윤명길
    • 유통과학연구
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    • 제11권12호
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    • pp.71-81
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    • 2013
  • Purpose - This study investigated the effects of consumers' selection criteria for environment-friendly agricultural products on purchase intention and the effects of consumers' attitudes and the reliability of environment-friendly agricultural products on purchase intention by using the theory of planned behavior. Subjective norms of variables of behavioral intention, attitudes toward behavior and control of the behavior were used to create selection criteria, consumers' attitudes and reliability of environment-friendly agricultural products. The study investigated the effects of consumers' selection criteria, attitudes, and reliability of environment-friendly agricultural products on purchase intention constructing models and hypotheses of mediation and moderation between selection criteria for agricultural products and purchase intention by consumers' attitudes and reliability. Research design, data, and methodology - The findings were as follows: first, consumers' selection criteria for environment-friendly agricultural products had a significantly affirmative influence upon purchase intention. Health was the most important factor of selection criteria convenience was more important than quality and familiarity was next. Consumers' attitudes and trust had a significant influence on purchase intention. Second, testing showed that consumers' attitude and trust partially mediated selection criteria: sub-factors and purchase intention were important in selection criteria. Third, testing showed that consumers' attitude and trust had a significant moderation effect between selection criteria and purchase intention. In the test of the moderation effect between sub-factors of selection criteria and purchase intention, consumers' attitude had a significantly positive influence upon health, convenience, and familiarity, and had no significant influence upon quality and purchase intention. Consumers' trust had no significant influence upon health, convenience, and quality. Results - The study provided several theoretical implications: first, an empirical analysis was undertaken with selection criteria for environmental-friendly agricultural products, consumers' attitude, and trust to investigate subjective norms, attitude toward behavior and control of behavior based on the theory of planned behavior. Second, this study investigated both the mediation effect and moderation effect of consumers' subjective norms on attitudes toward behavior, the mediating effects of perceived behavior control and changes of behavioral intention depending upon size and direction of the variables. This study also provided several practical implications. Conclusions - First, consumption of environment-friendly agricultural products did not increase despite rapid increase of production therefore, promotion of consumption and distribution was needed considering the supply and demand of the products. Second, definite standards for selection criteria were suggested to build up consumers' attitude and trust. Consumers' attitude could be improved by factors including the brand of environment-friendly agricultural products, consistent quality, solving physiological problems caused by adverse effects of environmental problems, supplementary approaches, treatment of adverse effects by eating food, and the development and supply of products in accordance with changes of lifestyle. Finally, consumers' demand for sub-factors of selection criteria could be much higher than health, convenience, and quality of the products. Therefore, a process was needed that could continuously check consumers' needs for the products. Limitations were described at the end of the study.

기준연도 조정에 따른 환산지수 민감도 분석 연구 (A Study on the Sensitivity of Conversion Factor According to Change of Base Year)

  • 오동일
    • 한국산학기술학회논문지
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    • 제21권4호
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    • pp.201-209
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    • 2020
  • 본 연구에서는 최근 수가계약 과정에서 논란이 되고 있는 기준연도 변경과 관련된 이슈를 살펴보았다. 이와 관련하여 기준연도 변경이 유형별 환산지수에 미치는 영향과 관련해 민감도분석을 실시하였다. 그리고 기준연도변경이 특정유형에 미치는 유리하거나 불리한 상황을 분석하였다. 또한 단일 환산지수 체계라고 가정하는 경우 기준연도 변경에 따른 환산지수 변동도 고찰하였다. 본 연구의 주요한 결론은 다음과 같다. 첫째, 기준연도를 현재시점에 가깝게 변경하는 경우 병원의 환산지수에는 유리한 효과가 발생한다. 둘째, 기준연도를 현재 시점에 가깝게 변경하는 경우 약국과 의원의 환산지수에는 불리한 효과가 발생하며 의원의 경우 불리한 효과가 크다. 셋째, 유형 전체에 단일 환산지수를 일괄적으로 적용한다고 가정하면 기준연도를 현재 시점에 가깝게 변경하는 경우 모든 유형에 유리한 효과가 발생한다. 기준연도 변동은 보험자와 의료공급자, 의료공급자 사이에 이해충돌을 가지고 올 수 있다. 따라서 자원 배분의 합리적인 근거를 바탕으로 상호 합의에 추진되어야 하며 손실이 초래되는 유형에 대해서는 한시적 보상을 위한 인센티브를 제시할 필요가 있다.

A Preliminary Study on the Inhibitory Effect of Chunghyul-dan on Stroke Recurrence on Patients with Small Vessel Disease

  • Cho, Ki-Ho;Jee, Nam-gue;Jung, Woo-Sang;Park, Seong-Uk;Moon, Sang-Kwan;Ko, Chang-Nam;Kim, Young-Suk;Jung, Woo-Sang
    • 대한한의학회지
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    • 제28권1호통권69호
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    • pp.224-236
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    • 2007
  • Background : Chunghyul-dan is a combinatorial herbal medicine; previous studies reported it had therapeutic effects for microangiopathy, a major part in the progression of small vessel disease, as well as having anti-hypertensive, anti-hyperlipidemic, anti-apoptotic, anti-oxidative, and anti-inflammatory activities. Therefor, we examined the inhibitory effect of Chunghyul-dan on stroke recurrence in patients with small vessel disease. Methods : We prescribed Chunghyul-dan at 600 mg a day to patients with small vessel disease, and monitored stroke recurrence, drug compliances, and adverse effect for 1 year. We then performed follow-up brain MRI to find new vascular lesions after 1 year of Chunghyul-dan medication. For the subjects lost to follow-up, we assessed their prognosis after 1 year by telephone. Results : There were 73 subjects treated with Chunghyul-dan for 1 year; new vascular events were found in 3. Of the 85 subjects lost to follow-up, fifty four could be contacted, and eight of them had stroke recurrence. One year of Chunghyul-dan medication reduced the odds ratio of stroke recurrence by 75% compared to the subjects lost to follow-up and the rate increased to 88%, when adjusted for other relevant risk factors for stroke recurrence. These reductions were much higher than those of aspirin and other kinds of conventional anti-platelets. There was no adverse effect in any of the study subjects. Conclusions : We suggest Chunghyul-dan could be useful for inhibition of stroke recurrence. Further study with a randomized controlled trial is needed to confirm this suggestion.

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