• The Korean Journal of Physiology and Pharmacology
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• 제6권2호
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• pp.101-107
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• 2002

In the present study, the postnatal developmental changes in the expressional levels of cardiac sarcoplasmic reticulum (SR) $Ca^{2+}$ regulatory proteins, i.e. $Ca^{2+}-ATPase,$ phospholamban, and $Ca^{2+}$ release channel, were investigated. Both SR $Ca^{2+}-ATPase$ and phospholamban mRNA levels were about 35% of adult levels at birth and gradually increased to adult levels. Protein levels of both SR $Ca^{2+}-ATPase$ and phospholamban, which were measured by quantitative immunoblotting, were closely correlated with the mRNA levels. The initial rates of $Ca^{2+}$ uptake at birth were about 40% of adult rates and also increased gradually during the myocardial development. Consequently, the relative phospholamban/$Ca^{2+}-ATPase$ ratio was 1 in developmental hearts. $Ca^{2+}$ release channel (ryanodine receptor) mRNA was about $50{\sim}60%$ at birth and increased gradually to adult level throughout the postnatal rat heart development. $^3[H]ryanodine$ binding increased gradually during postnatal myocardial development, which was closely correlated with ryanodine mRNA expression levels during the development except the ryanodine mRNA level at birth. These findings indicate that cardiac SR $Ca^{2+}-ATPase,$ phospholamban, and $Ca^{2+}$ release channel are expressed coordinately, which may be necessary for intracellular $Ca^{2+}$ regulation during the rat heart development.

• 치위생과학회지
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• 제20권1호
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• pp.25-33
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• 2020

Background: This study investigated the status of oral health promotion activities for adult workers in public health centers and industrial dental offices and provided basic data for the model development of oral health promotion program for adult workers in Korea. Methods: A questionnaire was developed separately according to the person who in charge of the oral health promotion activities in public health centers nationwide and dental hygienists working in 20 industrial dental offices. This survey was conducted through postal survey and consisted of 29 items and 35 items respectively, including 19 common items for general information, oral health promotion program status and opinion. Statistical analysis was performed using the IBM SPSS ver. 23.0. Results: We analyzed the data of 147 public health centers (57.9%) and 9 industrial dental offices (45.0%). A workforce with a lack of practice was the biggest barrier to oral health promotion activities for adult workers. However, both groups showed high intention for the practice of adult worker's oral health promotion activities. Also, they showed willingness to work together in an organic partnership to perform their roles (94.4% and 77.8%, respectively). Regarding the scope of cooperation in the implementation of the industrial oral health promotion activity linked to the public health center, dental hygienists of industrial dental offices responded that they could coordinate necessary matters and schedule management. Conclusion: The development of an oral health promotion program aided by the relationship between public health centers and industrial dental offices is essential for the oral health promotion of adult workers. The possibility of cooperation between the abovementioned centers was confirmed through this study. In a long-term perspective, it would be necessary to identify a method to institutionalize industrial dental hygienists for the provision of continuous oral health care in workplaces.

• 문화기술의 융합
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• 제8권6호
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• pp.389-395
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• 2022

본 연구는 성인대학생의 핵심역량모형을 개발하는 것을 목적으로 한다. 이를 위해 국내외 문헌연구를 분석하여 성인대학생의 핵심역량을 도출하였으며, 핵심역량의 타당성을 위하여 델파이 조사를 하였다. 이를 위해 SPSS 18.0 프로그램을 이용하여 분석하였다. 연구결과는 의사소통, 문제해결 및 메타, 대인관계, 자기관리·개발, 디지털 정보 문해, 전공지식, 시민의식, 융합, 인성, 전문직업과 글로벌로 총 11개의 성인대학생 핵심역량이 도출되었다. 성인대학생의 핵심역량모형은 델파이 조사의 결과를 바탕으로 01~11의 번호를 부여하여 개발하였다. 성인대학생의 핵심역량은 서로 유기적으로 연계되어 있어 하나의 핵심역량의 함양은 다른 핵심역량에도 영향을 미치는 것으로 나타났다.

• 한국양식학회지
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• 제21권4호
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• pp.239-243
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• 2008

A $3{\times}2$ factorial experiment was conducted to investigate the proper dietary protein and lipid levels for the growth of sub-adult flounder Paralichthys olivaceus reared during the summer season. Six experimental diets were formulated to contain three levels of protein (45%, 50% and 55%) and two levels of lipid (9% and 14%). Duplicate groups of fish (initial body weight of 298 g) were hand-fed to apparent satiation during the summer season ($21.8{\pm}1.7^{\circ}C$) for 60 days. Survival of each group was over 83% and there was not significant difference among all groups. Weight gain of fish fed the 45% protein diet with 14% lipid was not significantly different from that of fish fed the 50% and 55% protein diets with 9% and 14% lipids, but weight gain of fish fed the 45% protein diet with 9% lipid was significantly lower than that of fish fed the 55% protein diets with 14% lipid. Feed efficiency tended to increase with increasing dietary lipid level at each protein levels, although no significant differences were observed at 50% and 55% protein levels. Protein efficiency ratio, daily feed intake, condition factor and hepatosomatic index were not significantly affected by dietary protein and lipid levels. Crude lipid content of the liver tended to increase with increasing dietary lipid level at the same protein levels, but the opposite appearance was found for moisture content. The contents of moisture, crude protein and crude lipid of the dorsal muscle were not significantly affected by dietary protein and lipid levels. Based on data obtained form this study, inclusion of dietary protein at level of 45% appears sufficient to support optimal growth, and an increase of dietary lipid level from 9% to 14% has beneficial effects on feed utilization of sub-adult flounder during the summer season.

• International Journal of Industrial Entomology and Biomaterials
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• 제11권1호
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• pp.21-25
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• 2005

As a means for year-round rearing of bumblebee, CO$_{2}$ -narcosis time favorable for colony development was identified in Bombus terrestris. CO$_{2}$ -narcosis time divided into five classes: 11 days of adult emergence (A-11), the day of adult emergence (A-0), late pupal stage (LP), middle pupal sta ge (MP), and early pupal stage (EP). In egg-laying characteristics, the oviposition rate of LP, A-11 and A-0 was over 76.0$\%$, but that of MP and EP was less than 61.1 $\%$. At the same time, the days needed to first oviposition shortened to 9.8 ­10.5 days in A-11, A-O and LP, comparing to 13.7 -16.1 days in MP and EP. The rate of colony foundation, progeny-queen produced and period of colony foundation of A-11 were the best results in among those at different CO$_{2}$-treatment time. The number of worker produced was 109.2 -110.5 in A-H, LP and A-H, comparing to 82.0 - 86.8 in MP and EP. Also, the number of progeny-queen produced of A-H, A-O and LP was 36.1, 41.0 and 71.3, respectively, which corresponded to 1.5 - 3.1 fold higher than MP and EP. Taken these together, CO$_{2}$-narcosis time favorable for colony development was determined to be 11 days of adult emergence. Also, the day of adult emergence and late pupal stage showed a positive effect on the oviposition and colony development in CO$_{2}$-narcosis time.

• 농촌계획
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• 제15권4호
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• pp.89-107
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• 2009

The main objective of the present study is to find out which factors affect coresidence between older Korean parents and their adult children and to examine the regional patterns of the phenomenon. The 1980, 1995 and 2005 Korea census data are used to investigate the determinants of two types of parent-child coresidence. The two types are coresidence with married adult children and one with unmarried adult children. The study takes advantage of the multilevel mltinomial logit model, allowing the model to capture regional differences. Findings from the study are: (1) Korean parents' coresidence with their married adult children and one with their unmarried adult children are distinctive in their determinants; (2) variables related to wealth or economic status are positively related with possibilities of both types of coresidence; and (3) considerable regional differences in the possibility of coresidence do exist among regions in Korea.

• The Journal of Korean Physical Therapy
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• 제13권2호
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• pp.407-420
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• 2001

This article provide information pertaining to recent scientific findings regarding neural and motor control development and the effects of brain damage on that development. Clinical and scientific issues pertaining to perinatal and adult-onset brain damage are discussed. The article is intended to provide the clinician with new information that will assist in patient assessment and the establishment of therapeutic interventions

• Animal cells and systems
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• 제1권3호
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• pp.483-489
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• 1997

This study was performed to investigate the differentiation and distribution of choline acetyltransferase (ChAT}-immunoreactive cells in the magnacellular preoptic nucleus (MCPO) of the postnatal and adult rat forebrains, utilizing techniques of immunocytochemistry. According to the cell shape and the ratio of long axis versus short axis of cell soma, the ChATimmunoreactive nerve cells in the MCPO were classified into six types: 1) round, 2) oval, 3) elongated, 4) fusiform, 5) triangular, and 6) polygonal types. Frequency distributions of the oval and round nerve cells on the postnatal day (PND) 0 were observed to be high. But in the adult, frequency distributions of the same cells were shown to decrease. Compared to those of the postnatal rats, frequency distributions of elongated, fusiform, triangular, and polygonal nerve cells in the adult were increased. The total mean volumes of ChAT-immunoreactive cell somata in the MCPO of PND 0 rat were the lowest, while those in the PND 17 rat were shown to be the highest and decreased in the adult. The soma volumes of the immunoreactive cells at the PND 17 were evenly distributed, but those in the other developmental stages (e.g. PND 7 and adult) appeared to exhibit unimodal distributions. On the electron micrography, the free ribosomes, polysomes, and rough endoplasmic reticula (RER) of the nerve cells in the MCPO of PND 21 rat forebrains were immunoreactive to ChAT in the tissues untreated with triton X-100. According to the observations in the present study, it is considered that the ChAT-immunoreactive nerve cells in the MCPO of the rat forebrains are differentiated throughout the following processes during the postnatal development: 1) increase in cell soma volumes, 2) development of neurites, 3) increase in the frequency of differentiated cell types, and 4) decrease in cell soma volumes. The ribosomes, polysomes, and RER are considered to be closely related to the intracellular localization and biosynthesis of the ChAT but not Golgi complex.

• 정보교육학회논문지
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• 제25권5호
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• pp.813-824
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• 2021

A사이버교육시스템 성인학습자의 자기조절학습 관련 학습 추이를 분석하여 교육 성과를 높이기 위해 인공지능을 활용한 알고리즘 모델을 다양하게 설계하고, 그것을 실제 데이터에 적용함으로써 성능을 평가하였다. 이를 위해 A사이버교육시스템에서 115명의 성인학습자의 로그 데이터를 분석하였다. A사이버교육시스템 성인학습자들은 대부분 권장 학습 시간 이상을 학습하였으나, 학기 말에는 권장 학습 시간 대비 실제 학습 시간이 현저하게 감소하였다. VOD 참여율이나 형성평가 참여율, 학습 활동 참여율에서도 학습 후반부에 접어들수록 학습 참여율이 떨어졌다. 따라서 교육 성과를 높이려면 학습 시간이 후반에도 지속될 수 있도록 지원해야 한다 판단하여 후반부에 학습 시간이 떨어지는 학습자를 찾아내기 위해 Tensorflow를 활용한 인공지능 모델을 개발하여 수강 시작 날짜별 학습 시간을 예측하였다. 그 결과, CNN 모델을 활용하여 단일 출력 또는 다중 출력을 예측할 경우 다른 모델에 비해 평균 절대 오차가 가장 낮게 나타났다.

• 한국산학기술학회논문지
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• 제19권11호
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• pp.711-720
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• 2018

본 연구는 평생교육자의 핵심역량이 성인학습자의 지혜를 매개효과로 하여 생애능력에 미치는 영향을 살펴보는 데 그 목적을 두었다. 본 연구 대상은 경기도에 위치한 평생교육기관에서 평생교육 프로그램에 참여하고 있는 성인학습자를 대상으로 이어졌으며, 최종적으로 총 520부가 분석에 사용 되었으며, 분석방법으로는 SPSS 23.0과 AMOS 23.0을 사용하여 분석하였다. 본 연구의 주요 결과는 첫째, 평생교육자의 핵심역량과 성인학습자의 생애능력 및 성인학습자 지혜 간의 관계를 살펴 본 결과, 모든 변인 간 상관계수는 정적인 것으로 나타났다. 둘째, 평생교육자의 핵심역량과 지혜가 성인학습자의 생애 능력에 미치는 영향을 살펴 본 결과, 전체적으로는 66.8%의 영향력이 있었고, 성인학습자의 생애능력에 가장 많이 미치는 변인은 성인학습자 지혜의 창의적 문제해결 이었으며, 그 다음으로는 타인배려, 변화수용, 성별 순으로 나타났다. 셋째, 평생교육자의 핵심역량이 성인학습자의 생애능력에 미치는 영향에서 성인학습자 지혜의 매개효과를 살펴 본 결과, 평생교육자의 핵심역량이 성인학습자의 생애능력에 미치는 영향은 유의하지 않았으나, 성인학습자 지혜를 통해서는 영향력이 검증되어 지혜가 완전매개 하는 것으로 나타났다. 이러한 결과들을 종합하면 성인학습자의 생애능력에는 평생교육자의 핵심역량과 성인학습자 지혜가 중요한 변인임이 증명되었으며, 이러한 지혜는 성인학습자의 삶의 질을 높이고, 궁극적으로는 생애능력의 향상을 위한 변수임을 알 수 있다.