• Advances in pediatric surgery
• /
• 제10권2호
• /
• pp.107-111
• /
• 2004

Recently, the incidence of perinatally detected asymptomatic adrenal gland masses has increased because of widespread use of radiological diagnostic tools. However, optimal treatment of these masses has not been determined. The aim of this study is to elucidate the treatment guideline of perinatally diagnosed adrenal gland masses. The authors retrospectively reviewed the medical records of the 11 patients with asymptomatic adrenal gland mass, detected perinatally, between 1999 and 2004. Six cases were detected by prenatal ultrasound and 5 cases were incidentally detected by postnatal ultrasound. Six patients (surgery group) underwent mass excision. The pathologic diagnoses were neuroblastoma (n=4), adrenocortical adenoma (n=1) and adrenal pseudocyst (n=1). The indications for operation were suspicion of neuroblastoma (n=5) or absence of size decrease during observation (n=1). Three of the 5 suspicious cases of neuroblastoma and one case under observation were proven to be neuroblastoma. There was no surgical complication in the urgery group. All neuroblastoma patients have been well during the follow up period ($24.4{\pm}14.4$ month) without evidence of recurrence. Five cases (observation group) were closely observed because of the benign possibility or size decrease in follow up ultrasound. During the observation period ($39{\pm}21$ week), 4 cases showed complete spontaneous resolution and 1 case showed markedly decreased size of the mass but could not be followed up completely. Surgical resection of the perinatally diagnosed asymptomatic adrenal gland mass is a safe treatment method especially in case of suspicion of neuroblastoma, but closed observation can be applied.

• Advances in pediatric surgery
• /
• 제19권2호
• /
• pp.140-144
• /
• 2013

Adrenal venous malformation is an uncommon disease. We report a case of an incidentally diagnosed adrenal cystic mass during an evaluation for gastritis in a child. A 14-year-old girl admitted to our pediatric department for epigastric pain. After the gastroscopy, she was diagnosed with hemorrhagic gastritis. A 5.5 cm-sized cystic mass was incidentally found adjacent to her left adrenal gland during an ultrasound examination for evaluating her abdominal symptoms. She underwent laparoscopic surgery for the diagnosis and treatment of this cystic mass, which was confirmed to be venous malformation at pathologic diagnosis.

• Journal of Yeungnam Medical Science
• /
• 제36권3호
• /
• pp.265-268
• /
• 2019

Adrenal cystic lymphangiomas are extremely rare entities that are often identified incidentally, with less than 60 cases reported to date. We found a protruding ovoid mass consisting of a multiloculated cystic lesion within right adrenal gland in the cadaver of a 75-year-old Korean man. The epithelial cells lining the adrenal cyst were diffusely positive for cluster of differentiation 31 and podoplanin, and negative for pan-cytokeratin. The histopathological diagnosis confirmed a cystic lymphangioma arising from the adrenal gland. Post-mortem findings of the present case are discussed based on the clinicopathological features of adrenal cystic lymphangiomas.

• 한국동물위생학회지
• /
• 제36권4호
• /
• pp.321-325
• /
• 2013

A mass of the adrenal gland was observed during a routine necropsy of a female 23-year-old Asian Water Buffalo (Bubalus bubalis) at Seoul Zoo in Gyeonggi Province, Korea. The animal showed no clinical signs but the necropsy examination revealed hydropericardium, ascites, hydrothorax and edema of the intestinal wall, lung and adrenal gland. Histopathologically, the neoplastic cells of the right adrenal gland were arranged in lobules supported by a fine fibrovascular stroma. The neoplastic cells had round hyperchromatic nuclei and granular eosinophilic to basophilic cytoplasm. Immunohistochemically, tumor cells were positive for chromogranin A and S-100 and negative for vimentin, synaptophysin and cytokeratin. Based on the above findings, this case was diagnosed as a pheochromocytoma. To the best of our knowledge, this is the first report of a pheochromocytoma in an Asian Water Buffalo (Bubalus bubalis).

• Investigative Magnetic Resonance Imaging
• /
• 제17권4호
• /
• pp.321-325
• /
• 2013

간세포암은 부신을 포함하여 여러 장기에 전이를 일으킬 수 있다. 그러나, 간의 병변 없이 부신으로 전이된 간세포암의 예는 매우 드물다. 저자들은 부신의 종괴로 처음 발현한 전이성 간세포암의 전산화 단층촬영 (CT), 자기공명영상 소견을 보고하고자 한다. 간세포암의 전이로 인한 부신 종괴는 MRI에서 간세포암과 유사한 신호강도와 조영증강 양상을 보이고 있었다.

• 대한수의학회지
• /
• 제42권3호
• /
• pp.389-392
• /
• 2002

A 17-year-old female tiger (Panthera tigris altica) was found dead after suffering from continuously growing mass at the right mammary gland area. At necropsy, a firm tan mass approximately 25 cm in diameter was noted at the ventral abdomen. The mass was not fixed to the adjacent tissue and mottled tan to red on cut sections. Chains of similar nodules ranging from 2 to 5 cm in diameter were also present along the right mammary glands region. Histologically, the neoplastic masses consisted of lobules that were filled with pleomorphic neoplastic cells and separated by fibrious conntective tissue. The neoplastic cells have hyperchromatic nuclei with prominent nucleolus and moderate amount of cytoplasm. The degree of mitosis was high. Multiple areas of necrosis, hemorrhage, mineralization and tumor emboli were also noted. Metastasis to the regional lymph nodes, lung, liver, spleen, kidney, and adrenal gland were observed. Based on the gross and histopathologic examinations, a diagnosis of lobular type metastatic mammary gland carcinoma was made.

• Advances in pediatric surgery
• /
• 제7권1호
• /
• pp.68-72
• /
• 2001

Prenatally diagnosed neuroblastomas have been reported in increasing numbers over the past several years. The vast majority are in favorable stages of the disease (stage I, II, IV-S). The authors experienced one case of stage IV-S neuroblastoma of the adrenal gland with liver metastasis, which regressed spontaneously after removal by adrenalectomy. This patient was noticed to have an abdominal mass at prenatal ultrasonography performed at 36weeks of gestation. This tumor was a neuroblastoma of the left adrenal gland with multiple liver metastases. Left adrenalectomy and liver biopsy were performed at 3 months of age. Thirty-eight months after surgery, an MRI demonstrated that the hepatic metastatic lesions had completely regressed without chemotherapy or radiation.

• 한국임상수의학회지
• /
• 제26권3호
• /
• pp.268-272
• /
• 2009

An-11-year-old male Shih-tzu was admitted to emergency care unit of Haemaru Referral Animal Hospital with signs of dyspnea, anuria and depression. There were abnormalities on complete blood count and serum chemistry included leukocytosis with mild left shift, mild azotemia, and increased ALT activity. Fluid therapy(0.9% saline, 40 ml/hr) and antibiotics were immediately initiated. The patient began to vomit after 5 hours' rest and pale mucous membrane, bradycardia, and hypertension were noted. Abdominal ultrasonography revealed enlarged left adrenal gland and thrombus in caudal vena cava(CVC). Result of ACTH stimulation test was normal. Cytology of ultrasound-guided FNA smears showed numerous naked nuclei, which was suggestive of adrenal medullar tumor. Concentrations of 24 hour urine metanephrine and normetanephrine was moderately increased compared to those of a control dog. Adrenal mass was surgically removed, and biopsy of the CVC mass was obtained. After surgery the patient began to recover but the dog acutely developed cardiopulmonary arrest and died. On histopathology the adrenal mass and biopsy of the CVC mass were consistent with pheochromocytoma. On electron microscopic view norepinephrine specific granules were found in the cytoplasm of tumor cells.

• 한국임상수의학회지
• /
• 제26권1호
• /
• pp.95-100
• /
• 2009

A 15-year-old, spayed female maltese dog was presented with polydipsia, polyuria, polyphagia, abdominal distention, alopecia and hyperpigmentation. The complete blood counts were in normal range, and the serum biochemistry revealed elevated level of glucose and globulin. Mild hepatomegaly was seen on radiography of abdomen. Abdominal ultrasonography revealed the uniformly enlarged left adrenal gland measured 2.4 cm in diameter. ACTH stimulation test and LDDST revealed hyperadrenocorticism. HDDST revealed pituitary dependent hyperadrenocorticism. On CT images, isodense mass with contrast enhancing was seen in left adrenal gland. Cytologic result is consistent with benign tumor. Adrenal mass was surgically removed and evaluated. Histopathologic examination revealed adenocortical adenoma.

• 한국임상수의학회지
• /
• 제32권3호
• /
• pp.263-267
• /
• 2015

복부 초음파 영상검사에서 부신 종괴가 확인된 세 마리의 개에서 지연형 조영증강 전산화단층촬영을 적용한 영상검사가 진행되었다. 조영제 주입 전과 주입 직후, 5분의 지연 시간 후에 CT 검사를 하였으며 위치, 조영 전과 후의 양상, 주변 장기와의 관계, washout 정도를 평가하였다. 세 마리 개 모두에서 부신절제술이 실시되었으며 조직병리 검사 결과 골수지방종을 동반한 크롬친화세포종, 부신샘종, 부신암종으로 진단되었다. 부신암종을 가진 한 마리의 개를 제외하고는 수술 후 회복하여 퇴원하였다.