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Metastatic Mammary Gland Adenocarcinoma in a Tiger (Panthera tigris altica)  

Shin, Nam-Sik (College of Veterinary Medicine and School of Agricultural Biotechnology, Seoul National University)
Kwon, Soo-Wahn (Everland Zoological Garden)
Kim, Yang-Beum (Everland Zoological Garden)
Kim, Bang-Hyun (College of Veterinary Medicine and School of Agricultural Biotechnology, Seoul National University)
Oh, Sang-Yeon (College of Veterinary Medicine and School of Agricultural Biotechnology, Seoul National University)
Kim, Dae-yong (College of Veterinary Medicine and School of Agricultural Biotechnology, Seoul National University)
Publication Information
Korean Journal of Veterinary Research / v.42, no.3, 2002 , pp. 389-392 More about this Journal
Abstract
A 17-year-old female tiger (Panthera tigris altica) was found dead after suffering from continuously growing mass at the right mammary gland area. At necropsy, a firm tan mass approximately 25 cm in diameter was noted at the ventral abdomen. The mass was not fixed to the adjacent tissue and mottled tan to red on cut sections. Chains of similar nodules ranging from 2 to 5 cm in diameter were also present along the right mammary glands region. Histologically, the neoplastic masses consisted of lobules that were filled with pleomorphic neoplastic cells and separated by fibrious conntective tissue. The neoplastic cells have hyperchromatic nuclei with prominent nucleolus and moderate amount of cytoplasm. The degree of mitosis was high. Multiple areas of necrosis, hemorrhage, mineralization and tumor emboli were also noted. Metastasis to the regional lymph nodes, lung, liver, spleen, kidney, and adrenal gland were observed. Based on the gross and histopathologic examinations, a diagnosis of lobular type metastatic mammary gland carcinoma was made.
Keywords
Tiger; mammary gland; tumor;
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