• Clinical and Experimental Pediatrics
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• v.57 no.12
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• pp.526-532
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• 2014

Purpose: Matrix metalloproteinases (MMPs) have been implicated in atherosclerosis, and therefore, are considered risk factors for metabolic dysfunction in adults. However, there is little data on circulating levels of MMPs and tissue inhibitors of MMPs (TIMPs) with regard to obesity-related biomarkers in the general adolescent population. In the present study, we determined the associations of MMP-8, MMP-9, and TIMP-1 levels and MMP-8/TIMP-1 and MMP-9/TIMP-1 ratios with obesity-related biomarkers in apparently healthy adolescent boys. Methods: We measured MMP and TIMP concentrations in plasma samples using the enzyme-linked immunosorbent assay and analyzed their associations with obesity-related biomarkers, such as liver enzymes and lipid profiles, in a sample of 91 Korean boys aged 13-14 years who participated in a general health check-up. Results: The mean age of the boys was $13.8{\pm}0.3years$; 72 boys were normal weight and 19 were overweight/obese. The Pearson correlation coefficients revealed a significant correlation between MMP-8 and aspartate aminotransferase (r=0.217, P=0.039) and alanine aminotransferase (r=0.250, P=0.017) and between TIMP-1 and aspartate aminotransferase (r=0.267, P=0.011). In a multivariate linear regression analysis, serum alanine aminotransferase was positively associated with the MMP-8 level. There were no significant differences in the MMP-8, MMP-9, and TIMP-1 levels or MMP-8/TIMP-1 and MMP-9/TIMP-1 ratios between control and overweight/obese subjects. Conclusion: We found a significant association between the MMP-8 level and alanine aminotransferase in the apparently healthy adolescent boys. These findings indicate that there may be a pathophysiological mechanism underlying the relationship between MMP-8 and liver enzymes in young adolescents.

• Clinical and Experimental Pediatrics
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• v.64 no.12
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• pp.619-627
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• 2021

Pediatric obesity has become a serious public health issue. The prevalence of obesity in children and adolescents has increased worldwide and in Korea over several decades. Obese children are more likely to be obese adults with an increased cardiovascular risk. Therefore, maintaining a healthy weight and preventing obesity during childhood are of critical importance. Moreover, obese children and adolescents often have endocrine comorbidities such as prediabetes, type 2 diabetes, dyslipidemia, metabolic syndrome, polycystic ovary syndrome, and central precocious puberty. Hence, the early implementation of obesity management using a multidisciplinary team approach and screening for these comorbidities in obese children and adolescents are required with the appropriate management of each comorbidity and/or specialist referral.

• The Journal of Pediatrics of Korean Medicine
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• v.21 no.3
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• pp.157-176
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• 2007

Objectives The relationships between adolescent depression and obesity, life style has been reported, but usually study results were not consistent with the study before. This study was designed to evaluate clear relationship between obesity and depressive trends, life styles in middle school students. Methods The study participants were the 1th, 2th grade students from one middle school in Kang dong Gu, Seoul(479 Students). The participants were measured their height and weight, and they were also surveyed by questionnaire. We diagnosed the students as depressives when they scored 10 points or above on Children's Depression Inventory(CDI) of Kovacs and Beck. Results The mean depression score in the obese group was significantly higher than that of the normal body weight group, and the more severely obese the group was, the higher the depression scores for this group were. The depression score of the boys obese group was higher than the girls obese group. The depression score was significantly higher in the obese group of people who hate to do exercising, like computer games and like watching TV instead, than in the group of people who like to do exercising and don't play computer games. Conclusions This study showed that depressive mood during adolescent was related to obesity and obesity-related lifestyles.

• Korean Journal of Health Education and Promotion
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• v.14 no.2
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• pp.171-184
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• 1997

The purpose of this study was to identify the adolescent girl's weight control practices, degree of obesity and body image. The data were collected from July 1st to 15th, 1996 using the questionnaire and the physical examination record. The subjects of this study were 295 junior high school girls. Darta were analyzed with percentages, means, t-test, ANOVA, Kruscal-Wallis one way ANOVA, Scheffe test and pearson correlation coefficients using the SPSS program. The results were as follows: 1. The mean for the degree of obesity in subjects was -1.26%. The 34.2% of the subjects were underweight, the 46.8% were normal, the 9.2% were overweight and the 9.8% were obese. The girls who perceived themselves obese were 39% and only the 47% of them were really over-weight and obese. 2. The mean score of body image was 139.30. It was 145.51 for underweight girls, 128.07 for normal weight girls and 125.17 for obese girls. The higher the degree of obesity was, the lower body image score was. The body image score of the girls who perceived themselves obese was significantly lower than that of the girls who perceived themselves normal or underweight. 3. The 65.1% of subjects experienced weight control practices. They reported that they had used the following weight control methods such as diet(42.2%), exercise(35.9%), diet and exercise(15.1%) and others including drug(6.8%). The degree of obesity was significantly higher and the body image score was significantly lower in the case of the girls who had weight control experiences than in the case of those who had no weight control experiences. 4. The 60% Of the subjects often had 2 meals per day. The 48.8% of the subjects tended to skip breakfast, the 7.8% would skip lunch and the 20% did not have dinner. The higher the degree of obesity was and the lower body image score was, the more the girls would skip their meals. In conclusion, many adolescent girls tended to believe their body weight heavier than their real body weight. Many girls who were not overweight and obese tried to lose weight. In the case of the girls whose degree of obesity was high or who perceived themselves obese, the body image score tended to get lower and the weight control practices tended to be increased.

• Clinical and Experimental Pediatrics
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• v.48 no.1
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• pp.21-26
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• 2005

Purpose : The aim of this study is to find the prevalence of obesity, the serum lipid levels and the age at menarche in adolescent female athletes and to examine the effects of exercise in adolescent stage. Methods : With a questionnaire regarding their age at menarche, physical measurement, body fat, and blood samples of the serum lipid levels to evaluate the hyperlipidemia were obtained from adolescent female athletes(n=107) and general adolescent students(n=650) who didn't exercise at regular intervals, aged 12 to 18 years. Results : The mean weight in the athletes' group was $53.3{\pm}7.3kg$ which was similar with $54.3{\pm}8.0kg$ in the control group. The mean height in the athletes' group was $161.4{\pm}5.4cm$, which was taller than $158.9{\pm}5.3cm$ in the control group. The prevalence of obesity by obesity index, body fat, and BMI in the athletes' group were significantly lower than in control group. There was no significant difference in age at menarche between two groups($12.6{\pm}1.3$, $12.9{\pm}1.2$). The levels of cholesterol, LDL cholesterol, and HDL cholesterol in the athletes' group were higher than in the control group. The levels of triglyceride in the athletes' group was lower than in control group. Conclusion : These data suggest the importance of exercise in adolescents for the prevention of obesity since it may reduce body fat and increase the height. There was no negative effect of exercise on the age at menarche. We think that more controlled assessment of nutrition, diet habit, hormonal effect and height are warranted to find the correlation with hyperlipidemia and exercise at the adolescent stage.

• Journal of the Korean Society of Clothing and Textiles
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• v.19 no.3
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• pp.516-524
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• 1995

The purpose of this study was to analyze the variation of body shape and to. divide growth period into some age groups based on body type. Duncan Test, Heath-Carter's somatotyping method and allottery equation (y=baa) were applied to semiautomatic data concerning obesity/leakiness. The materials were 309 females aged from 12 to 17 years old. The following results were obtained: 1. In the Developmental trend of the human body, the 12-13 age groups belonged to the acceleration stage of adolescent growth spurt. The 14-15 age groups belonged to the latter period of adolescent growth. The 16-17 age groups belonged to the termination stage of adolescent growth. 2. In the Heath-Carter's somatotyping method, the average somatotype changed into M.M- C-C-M-D with age. 3. In the alphamerical analysis, the first critical point appeared at the stature 146 Cm in case of weight, LBM and fat. The second critical point appeared at the stature 154-157 Cm in case of LBM and Fat. All the three measurement showed positive allotmentty.

• Journal of the Korean Society of Food Culture
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• v.13 no.3
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• pp.207-214
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• 1998

This study was undertaken to assess eating habits and food consumption pattern of 365 adolescent girls in Kwangju area. Subjects were divided into 3 groups based on relative body weight as obesity index. Anthropometric data showed that mean height and weight were $161.9{\pm}19.0cm$ and $53.3{\pm}7.2kg$ respectively which are similar to those in the Korean Standard Growth data. Mean BMI and relative body weight were 20.50 and 97.1%. Age of menarche in the subjects significantly influenced the obesity index. Food habit score in the underweight group was significantly lower than that in the normal group at ${\alpha}=0.2$ level by multiple range test. Obesity was significantly associated with more frequent and irregular eating. It seems that students in the obese group were concerned on their body weight and tended to consume much vegetable. Obese group consumed more fruits, less butter and fruit juice compared to other groups. It might be suggested that more effective nutrition program might be developed and implemented to ensure good food habit of adolescent girls including obese as well as underweight group.

• The Journal of Pediatrics of Korean Medicine
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• v.24 no.1
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• pp.77-92
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• 2010

Objectives The relationship between depression, obesity, life style of adolescents has been reported, but the results were not consistent. Thus this study was designed to find out the relationship. Methods The participants were the first and second grade middle school students. The participants were asked to measure their height and weight etc, and were asked to survey questionnaires. To diagnose the students' degree of depression, Children's Depression Inventory(CDI) by Kovas and Beck. Results The average depression score in the obese group was significantly higher than that of the normal body weight group. In addition, male obese group scored higher on CDI than the female obese group, and the obese group of participants who don't exercise, but like to play computer games and watch TV scored higher on CDI than the group who exercise and don't play computer games. Conclusions This study proved that depression in adolescent was closely related with obesity and obesity-related lifestyles. "The research was supported by the Kyung Hee University Research Fund in 2007"(KHU-20071638).

• Korean Journal of Health Education and Promotion
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• v.9 no.1
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• pp.88-102
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• 1992

The exact estimation of physical growth by Obesity level has important meaning to the health care and evaluation on adolescent girls. So this study tried to clear the relationship between weight and body fat by using data for the height, weight of 124 elementary school children and high school student in Seoul. Then this study tried to show the physical growth pattern and various characteristics by Obesity level by using longitudinal for the height, weight of 1113 high school students in Seoul, and it also tried to show what influencing factors on the physical growth of this aged population. The result could be summarized as follows. 1. The relationship between weight and body fat(%) has 0.81475(r) at age 9 and 0.69361(r) at age 18. Also the relationship between weight and lean body muscle(LBM %) has -0.81470(r) at age 9 and -0.64729(r) at age 18. 2. The weakness, normal and obesity groups were classified by Obesity level. In case of weakness group showed the very low Obesity level at age 8 to 11, in case of obesity group showed the high Obesity level at age 15 to 18. Also Rohrer index was decreasing tendency up to age 12 in weakness group and increasing tendency over age 14 in obesity group. 3. When the height and weight growth pattern was compared, height growth was superior to weight growth at age 9 to 14.5 in normal group. But weight growth was inferior to height growth at age 9 to 14.5 in normal group. In obesity group, weight growth was superior to height growth at age 7 to 18. On the other hand the height growth of weakness group was superior to the normal group and the obesity group except age 11 to 12. 4. On height velocity curve by PHV age obesity group showed the most growth amount per year(9.00Cm/yr), and the next is normal group(8.77Cm/yr), weakness group(8.70Cm/yr). Then the difference between PHV age and PWV age was within 1 year in these three groups. 5. In these three groups, height velocity curve by menarcheal age showed the PHV before 2~3 years of menarcheal age. And weight velocity curve by menarcheal age showed the remarkable PWV before 1 year of menarcheal age.

• Clinical and Experimental Pediatrics
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• v.52 no.12
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• pp.1321-1326
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• 2009

Prevalence of obesity in Korean children and adolescents has dramatically increased since the last 10-20 years. It is important to initiate prevention efforts early in childhood because prevalence of obesity in adolescence is the strongest predictor of its prevalence in adulthood. Intrauterine life, infancy, and preschool years may comprise the critical periods that are essential for the long-term regulation of energy balance therefore, obesity-prevention strategies should be initiated in utero and continued throughout childhood and adolescence. Families with high-risk children should be provided early education about maintaining normal weight. Encouraging physical activity and, especially, avoiding inactivity, are key challenges in the prevention of future obesity. Schools should be primarily involved in educating parents to discourage their children from excessively watching TV or playing computer games and eating unhealthy snacks and food. The involvement of medical practitioners is also important, especially, in the case of obese parents, obesity prevention strategies should be promoted from the first visit of pregnant women to the physicians. Health professionals can also be involved in obesity prevention because they are ideally equipped to identify young children at risk of obesity. Community and nation-wide efforts to increase awareness and promote environments that encourage physical activity and healthy nutrition are required.