• Journal of Pharmaceutical Investigation
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• 제29권2호
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• pp.127-136
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• 1999

In order to eliminate demerits of conventional dosage forms, dipotassium glycyrrhizate was formulated as a slim mucoadhesive film type dosage form. The mucoadhesive drug layer gel containing dipotassium glycyrrhizate was prepared using $Noveon^{\circledR}$ AA-1, hydroxypropylcellulose-M, ethylcellulose N 100 and citric acid, and the protective layer gel by using ethylcellulose N 100, $Eudragit^{\circledR}$ RS and castor oil. The viscosity of drug layer gel of mucoadhesive film was enhanced as the increased amount of $Noveon^{\circledR}$ AA-1 or hydroxypropyl cellulose-M. The drug content was unifonnly $1160{\pm}14.6\;{\mu}g$, and was varied within 3.5%. The optimum film dosage form showed a good fluidity and malleability of drug layer, with 179 g of thickness, pH 5.7, 411 min of in vitro adhesion time and 172 g in gravity adhesive strength. The release time of drug from the mucoadhesive film was significantly shorter but was delayed when polymers such as ethylcellulose was added. From these results, the new mucoadhesive film may be effective for the treatment of aphthous stomatitis.

• Steel and Composite Structures
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• 제26권3호
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• pp.265-272
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• 2018

A detailed study was carried out on the tensile properties of the single-lap joint of a steel panel bolted/bonded to a composite laminate with a flanging. Finite element model (FEM) was established to predict the strength and to analyze the damage propagation of the hybrid joints by ABAQUS/Standard, which especially adopted cohesive elements to simulate the interface between the laminate and adhesive. The strength and failure mode predicted by FEM were in good agreement with the experimental results. In addition, three influence factors including adhesive thickness, bolt preload and bolt-hole clearance were studied. The results show that the three parameters have effect on the first drop load of the load-displacement curve, but the effect of bolt-hole clearance is the largest. The bolt-hole clearance should be avoided for hybrid joints.

• 한국전기전자재료학회논문지
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• 제14권3호
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• pp.207-214
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• 2001

The conductive polymers, polyaniline (PANI) emeralidin base and 3,4-polyethylene dioxythiophene(PEDOT) were synthesized and coated on the PET film dealt with acryl type primer to study the electromagnetic shielding effectiveness. When both PANI and PEDOT were coated on the PET film dealt with acryl type priemer, their surface properties such as he adhesive increased. For PANI, when blended with the binder such as PMMA, it adhesive and surface hardness increased, too. The visible light transmittance decreased, while the electromagnetic shielding effectiveness increased, when coated thickness of PANI and PEDOT increased. For PANI, the electromagnetic shielding effectiveness increased as its surface resistance decreased. For PANI, when the surface resistance was 140 Ω/$\square$, the shielding effectiveness was found to be 11 dB in the far field, and 13 dB in the near field at 1 GHz. For PEDOT, when the surface resistance was 200 Ω/$\square$, the shielding effectiveness was found to be 3 dB in the far field, and 7dB in the near field.

• 복합신소재구조학회 논문집
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• 제2권2호
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• pp.13-19
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• 2011

본 연구에서는 강재가 맞대기 이음으로 연결될 경우 CFRP(Carbon Fiber Reinforced Plastic) 쉬트(sheet)를 맞대기 이음부에 접착할 경우 강재 및 CFRP 쉬트에 발생하는 응력을 해석하였다. CFRP 쉬트로 보강한 경우 접착제의 두께, 강재와의 접착 길이, CFRP 강도 변화를 매개변수로 사용하여 이 매개변수에 변화에 따른 이음부의 응력분포를 분석하였다. 또한 CFRP를 여러 층으로 접착할 경우 각 층의 강도를 다르게 변화시켜 맞대기 이음부에 유리한 응력분포를 나타내는 CFRP의 강도를 제시하였다. 본 연구를 위해 빠른 수렴성을 가지며 왜곡된 요소형상에서도 정확한 응력결과를 보이는 강화변형률장(Enhanced Assumed Strain Field)을 사용한 평면변형률 유한요소에 대한 프로그램을 작성하였다.

• Journal of Pharmaceutical Investigation
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• 제29권4호
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• pp.343-348
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• 1999

The purpose of this study is to prepare the controlled release adhesive patch containing naproxen. Pressuresensitive adhesive (PSA)-type patch was fabricated by casting of polyisobutylene (PIE.) and mineral oil in toluene. Membrane-controlled release (MCR)-type patch was prepared by the attachment of the controlled release membrane on the PSAtype patch. The membrane was mainly composed of Eudragit, polyethylene glycol(PEG) and glycerin. The drug release profile and skin permeation test with various patches were evaluated in vitro. The release of naproxen from PIE-based PSAtype patch with various loading doses fitted Higuchi's diffusion equation. However, the permeation of naproxen through hairless mouse skin from PSA-type patch followed zero-order kinetics. In MCR-type patch, thickness of controlled release membrane affected on the drug release rate highly. In the composition of membrane, the release rate was decreased as the ratio of Eudragit increased. The drug release from the MCR-type patch followed zero order kinetics. The permeation of naproxen through hairless mouse skin from MCR-type patch showed lag time for the intial release period and didn't fit the zero-order kinetics

• 한국재료학회지
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• 제34권3호
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• pp.125-137
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• 2024

Composite laminates are used in a wide range of applications including defense, automotive, aviation and aerospace, marine, wind energy, and recreational sporting goods. These composite beams still exhibit problems such as buckling, local deformations, and interlaminar delamination. To overcome these drawbacks, a novel viscoelastic autoclave bonding with tapered epoxy reinforcement polyurethane films is proposed. In existing laminates, compression face wrinkling and interlaminar delamination is caused in the sandwich beam. The unique viscoelastic autoclave spunbond interlayer bonding is designed to prevent face wrinkling and absorb and distribute stresses induced by external loads, thereby eliminating interlaminar delamination in the sandwich beam. Also, the existing special reinforcement causes stress concentrations, and the core is not effectively connected, which directly affects the stiffness of the beam. To address this, a novel tapered epoxy polyurethane reinforcement adhesive film is proposed, whose reinforcement thickness gradually tapers as it enters the core material. This minimizes stress concentrations at the interface, preventing excessive adhesive squeeze-out during the bonding process, and improves the stiffness of the beam. Results indicate the proposed model avoids the formation of micro cracks, interlaminar delamination, buckling, and local deformations, and effectively improves the stiffness of the beam.

• 한국멀티미디어학회논문지
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• 제12권7호
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• pp.971-978
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• 2009

본 연구는 위상제어형 루프안테나에 관한 것으로서, 유전체기판 상에 에칭기법이나 프린트기법으로 루프안테나용 동박패턴을 제작함에 있어, 루프에서 발생하는 전자계가 서로 보완위상이 되게 배치하여, 인접하는 루프패턴 간에서 방사되는 전자계가 서로 충돌하지 않게 방사되는 위상제어형 루프코일 배치에 관한 것이다. 이 방법으로 인접하는 각 루프코일이 서로 보완위상으로 배치되어 전자계가 원만하게 방사되어, 방사 손실이 없고 방사 효율이 뛰어나게 된다. 또한 복수 개의 각 루프코일의 길이를 서로 달리함으로 인해, 각 루프코일의 길이가 달라짐에 따라 공진주파수가 달라지고, 이러한 공진점이 다른 루프코일을 밀결합 시킴으로 인해 공진주파수 대역을 넓게 할 수 있고, 원하는 대역만큼 조절할 수가 있게 된다. 이로 인하여 크기 20mm$\times$20mm 이하의 사이즈에, 두께 0.4mm 이하의 박막의 유전체기판에 CDMA850 휴대폰대역 및 PCS, WCDMA 등의 안테나를 구현하여 게인 0dBi 이상 방사효율 60% 이상의 안테나를 구현할 수가 있다.

• 한국재료학회지
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• 제13권1호
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• pp.18-23
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• 2003

Properties of Ag thick films fabricated by using low temperature curable silver pastes were investigated. Ag pastes were consisted of polymer resins and silver powders. Ag pastes were used for conductive or fixing materials between board and various electrical and electronic devices. Low temperature curable Ag pastes have some advantages over high temperature curable types. In cases of chip mounting, soldering properties were required for screen printed Ag thick films. In this study, four types of Ag pastes were fabricated with different compositions. Screen printed Ag thick films on alumina substrates were fabricated at various curing temperatures and times. Thickness, resistivity, adhesive strength and solderability of fabricated Ag thick films were characterized. Finally, Ag thick films produced using Ag pastes, sample A and B, cured at $150^{\circ}C$ for longer than 6 h and $180^{\circ}C$ for longer than 2 h, and $150^{\circ}C$ for longer than 1 h and $180^{\circ}C$ for 1 h, respectively, showed low resistivities of $10^{-4}$ $∼10^{-5}$ Ωcm and good adhesive strength of 1∼5 Mpa. Soldering properties of those Ag thick films with curing temperatures at solder of 62Sn/36Pb/3Ag were also investigated.

• Journal of Korean Neurosurgical Society
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• 제59권3호
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• pp.250-258
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• 2016

Objective : A common cause of failure in laminectomy surgery is when epidural, peridural, or perineural adhesion occurs postoperatively. The purpose of this study is to examine the efficacy of a temperature-sensitive, anti-adhesive agent (TSAA agent), Guardix-SG$^{(R)}$, as a mechanical barrier for the prevention or reduction of peridural scar adhesion in a rabbit laminectomy model. Methods : Twenty-six mature rabbits were used for this study. Each rabbit underwent two separate laminectomies at lumbar vertebrae L3 and L6, left empty (the control group) and applied 2 mL of the TSAA agent (the experimental group), respectively. Invasive scar formation or inflammation after laminectomy was quantitatively evaluated by measuring the thickness of the dura, the distance from the surface of dura to the scar tissues, the number of inflammatory cells in the scar tissues at the laminectomy site, and the concentration of collagen in histological sections. Results : At 6 weeks postsurgery, the dura was significantly thinner and the distance from the surface of dura to the scar tissues was greater in the experimental group than in the control group (p=0.04 and p=0.01). The number of inflammatory cells was not significantly different in the two groups (p=0.08), although the mean number of inflammatory cells was relatively lower in the experimental group than in the control group. Conclusion : The current study suggests that the TSAA agent, Guardix-SG$^{(R)}$, could be useful as an interpositional physical barrier after laminectomy for the prevention or reduction of adhesion.

• Journal of the Korean Wood Science and Technology
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• 제26권1호
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• pp.97-105
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• 1998

This study examined the combined using effects of urea-formaldehyde (UF) resin and emulsifiable methylene diphyenyl diisocyanate (EMDI) resin to overcome performance limit of three-layer particleboards commonly made by UF resin. Two adhesive adding methods were applied with three types of resin combination system to each layer of particleboards. The one was simultaneously spreading method with emulsified compound resin (UF and EMDI) while the other was separately spreading method with unemulsified EMDI resin after UF resin spreading. The performance of particleboards bonded with 2% EMDI resin to the inner layers(IL) were similar to that of controls bonded with 8% UF resin. In the case of the emulsified compound resin application to the all layers of particleboards, there were marked reinforcing effects of EMDI resin, although a small amount of EMDI resin was mixed with UF resin. Especially bending MOR after 24 hours cold water-immersion and thickness swelling after 2 hours hot water-immersion of compound resin-bonded particleboards were remarkably different from those of pure UF resin-bonded particleboards. It was found that separately spreading method with unemulsified EMDI resin was more effective than simultaneously spreading method with emulsified compound resin to sustain the internal bond strength of particleboards after 24 hours cold water-immersion. In the resin combination systems to outer layers/inner layers of particleboards, water resistance and strength properties were superior in order of UF+EMDI/UF+EMDI > UF/UF+EMDI > UF/UF. And water resistance of particleboards was greatly dependent upon EMDI resin level in any adhesive adding method.