• Steel and Composite Structures
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• v.44 no.1
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• pp.33-47
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• 2022

This paper presents a finite element model for predicting the monotonic behaviour of bolted endplate joints connecting steel-concrete composite walls and steel beams. The demountable Hollo-bolts are utilised to facilitate the quick installation and dismantling for replacement and reuse. In the developed model, material and geometric nonlinearities were included. The accuracy of the developed model was assessed by comparing the numerical results with previous experimental tests on hollow/composite column-to-steel beam joints that incorporated endplates and Hollo-bolts. In particular, the Hollo-bolts were modelled with the expanded sleeves involved, and different material properties of the Hollo-bolt shank and sleeves were considered based on the information provided by the manufacture. The developed models, therefore, can be applied in the present study to simulate the wall-to-beam joints with similar structural components and characteristics. Based on the validated model, the authors herein compared the behaviour of wall-to-beam joints of two commonly utilised composite walling systems (Case 1: flat steel plates with headed studs; Case 2: lipped channel section with partition plates). Considering the ease of manufacturing, onsite erection and the pertinent costs, composite walling system with flat steel plates and conventional headed studs (Case 1) was the focus of present study. Specifically, additional headed studs were pre-welded inside the front wall plates to enhance the joint performance. On this basis, a series of parametric studies were conducted to assess the influences of five design parameters on the behaviour of bolted endplate wall-to-beam joints. The initial stiffness, plastic moment capacity, as well as the rotational capacity of the composite wall-to-beam joints based on the numerical analysis were further compared with the current design provision.

• Journal of Digital Convergence
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• v.20 no.2
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• pp.383-388
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• 2022

This study is about the elements of cosmetic's package design which MZ generation prefer and the effect on purchase. Naming, brand logo, color, typography, layout, illustration, matter & finish, and meaningful are classified 8 visual elements through the pilot study. After that this study analyzes specific visual elements which MZ generation prefer through online survey and In-depth interview based on the 8 visual elements. As a result of study, MZ generation prefer tidy and neat design to decorated style, and they feel brand logo is the most important thing of all 8 visual elements. In additional, meaningful of brand is barley able to compare with price, although it is significant visual element. This study may help to develop the way of the cosmetic's package design for MZ generation.

• Journal of Periodontal and Implant Science
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• v.52 no.1
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• pp.54-64
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• 2022

Purpose: This in vitro study was conducted to evaluate the effects of different debridement techniques and conditioning procedures on root surface morphology and blood clot stabilization. Methods: Two debridement techniques (curette [CU] vs. high-speed ultrasound [US]) and 2 conditioning procedures (ethylenediaminetetraacetic acid [EDTA] and phosphoric acid [PA]) were used for the study. Seven experimental groups were tested on root surfaces: 1) no treatment (C); 2) CU; 3) US; 4) CU+EDTA; 5) US+EDTA; 6) CU+PA; and 7) US+PA. Three specimens per group were observed under scanning electron microscopy (SEM) for surface characterization. Additional root slices received a blood drop, and clot formation was graded according to the blood element adhesion index by a single operator. Data were statistically analyzed, using a threshold of P<0.05 for statistical significance. Results: The C group displayed the most irregular surface among the tested groups with the complete absence of blood traces. The highest frequency of blood component adhesion was shown in the CU+EDTA group (P<0.05), while no differences were detected between the CU, US+EDTA, and CU+PA groups (P<0.05), which performed better than the US and US+PA groups (P<0.05). Conclusions: In this SEM analysis, EDTA and conventional manual scaling were the most efficient procedures for enhancing smear layer removal, collagen fiber exposure, and clot stabilization on the root surface. This technique is imperative in periodontal healing and regenerative procedures.

• Archives of Plastic Surgery
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• v.48 no.6
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• pp.703-713
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• 2021

The field of vascularized composite allografts (VCAs) has undergone significant advancement in recent decades, and VCAs are increasingly common and accepted in the clinical setting, bringing hope of functional recovery to patients with debilitating injuries. A major obstacle facing the widespread application of VCAs is the side effect profile associated with the current immunosuppressive regimen, which can cause a wide array of complications such as infection, malignancy, and even death. Significant concerns remain regarding whether the treatment outweighs the risk. The potential solution to this dilemma would be achieving VCA tolerance, which would allow recipients to receive allografts without significant immunosuppression and its sequelae. Promising tolerance protocols are being studied in kidney transplantation; four major trials have attempted to withdraw immunosuppressive treatment with various successes. The common theme in all four trials is the use of radiation treatment and donor cell transplantation. The knowledge gained from these trials can provide valuable insight into the development of a VCA tolerance protocol. Despite similarities, VCAs present additional barriers compared to kidney allografts regarding tolerance induction. VCA donors are likely to be deceased, which limits the time for significant pre-conditioning. VCA donors are also more likely to be human leukocyte antigen-mismatched, which means that tolerance must be induced across major immunological barriers. This review also explores adjunct therapies studied in large animal models that could be the missing element in establishing a safe and stable tolerance induction method.

• Journal of the Korea Institute of Building Construction
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• v.22 no.1
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• pp.1-10
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• 2022

Recently, due to the frequent occurrence of localized torrential rains and heat waves caused by abnormal climates. For this reason, it is necessary to develop an economical and eco-friendly rainwater detention facility that can secure the groundwater level through rainwater detention as well as flood prevention against concentrated rainfall by simultaneously implementing rainwater permeation and storage. In this study, the structural safety of an eco-friendly rainwater infiltration type detention facility made using eco-friendly inorganic binders including red clay was examined. Static analysis considering the constant load and additional vertical load and dynamic analysis considering the seismic spectrum were performed. As a result, it was found that the eco-friendly prefabricated rainwater infiltration type detention facility developed in this study has a maximum stress of about 68.1% to 75.4% and a maximum displacement of about 0.9% to 9.6% under the same load and seismic conditions compared to the existing PE block rainwater detention facility. It was confirmed that the eco-friendly prefabricated rainwater infiltration type detention facility secured excellent structural stability.

• Journal of Soil and Groundwater Environment
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• v.27 no.1
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• pp.39-49
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• 2022

Bottom ash generated from thermal power plants is mainly disposed in landfills, from which metals may be leached by infiltrating water. To evaluate the effect of metals in leachate on soil and groundwater, we characterized bottom ash generated from burning cokes, bituminous coal, the mixture of bituminous coal and wood pellets, and charcoal powder. The bottom ash of charcoal powder had a relatively large particle size, and its wood texture was well-preserved from SEM observation. The bottom ash of charcoal powder and wood pellets had relatively high K concentration from total element analysis. The eluates of the bottom ash samples had appreciable concentrations of Ca, Al, Fe, SO₄, and NO₃, but they were not a significant throughout the batch test. Therefore, it is considered that there is low possibility of soil and groundwater contamination due to leaching of metal ions and anions from these bottom ash in landfills. To estimate the trend of various trace elements, long-term monitoring and additional analysis need to be performed while considering the site conditions, because they readily adsorb on soil and aquifer substances.

• Computers and Concrete
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• v.28 no.6
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• pp.533-547
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• 2021

Calculating the shear capacity of slender reinforced concrete beams without shear reinforcement was the subject of numerous studies, where the eternal problem of developing a single relationship that will be able to predict the expected shear capacity is still present. Using experimental results to extrapolate formulae was so far the main approach for solving this problem, whereas in the last two decades different research studies attempted to use artificial intelligence algorithms and available data sets of experimentally tested beams to develop new models that would demonstrate improved prediction capabilities. Given the limited number of available experimental databases, these studies were numerically restrained, unable to holistically address this problem. In this manuscript, a new approach is proposed where a numerically generated database is used to train machine-learning algorithms and develop an improved model for predicting the shear capacity of slender concrete beams reinforced only with longitudinal rebars. Finally, the proposed predictive model was validated through the use of an available ACI database that was developed by using experimental results on physical reinforced concrete beam specimens without shear and compressive reinforcement. For the first time, a numerically generated database was used to train a model for computing the shear capacity of slender concrete beams without stirrups and was found to have improved predictive abilities compared to the corresponding ACI equations. According to the analysis performed in this research work, it is deemed necessary to further enrich the current numerically generated database with additional data to further improve the dataset used for training and extrapolation. Finally, future research work foresees the study of beams with stirrups and deep beams for the development of improved predictive models.

• Earthquakes and Structures
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• v.24 no.4
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• pp.259-274
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• 2023

In this paper, mechanical properties of periodic foundation made of concrete and rubber are investigated by a parametric study using the finite element method (FEM). Periodic foundation is a special type of seismic isolation foundation used in civil engineering, which is inspired by the meso-scale structure of phononic crystals in solid-state physics. This type of foundation is capable of reducing the seismic wave propagating though the foundation, therefore providing additional protection for the structures. In the FEM analysis, layered periodic foundation is frequently modelled due to its simplicity in numerical modeling. However, the isolation effect of periodic foundation on nuclear power plant has not been fully discussed to the best knowledge of authors. In this work, we construct four numerical models of nuclear power plant with different foundations to investigate the seismic isolation effects of periodic foundations. The results show that the layered periodic foundation can increase the natural period of the nuclear power plant like traditional base isolation systems, which is beneficial to the structures. In addition, the seismic response of the nuclear power plant can also be effectively reduced in both vertical and horizontal directions when the frequencies of the incident waves fall into some specific frequency bandgaps of the periodic foundation. Furthermore, it is demonstrated that the layered periodic foundation can reduce the amplitude of the floor response spectrum, which plays an important role in the protection of the equipment.

• Journal of Convergence Korean Medicine
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• v.5 no.1
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• pp.45-54
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• 2023

Objectives : Alcohol-induced liver disease advances as to reactive oxygen species (ROS) and cellular lipid peroxidation increase. We examined the hepatoprotective effects of Zingiber officinale Roscoe rhizome extract (ZR), Pueraria lobata Ohwi flower extracts (PF), and a newly developed herbal juice (HJ), which was a combination of ZR and PF extracts, against ethanol-induced hepatotoxicity. Methods: The study utilized the human hepatoma cell line HepG2 cells to validate the hepatoprotective effect of HJ (50~200 ㎍/mL) against ethanol (EtOH, 700 mM)-induced liver damage. Results: HJ effectively reduced the protein expression of sterol regulatory element-binding transcription factor 1, adiponectin, and AMP-activated protein kinase in EtOH-induced HepG2 cells. The levels of ROS, total cholesterol, and triglycerides, which are the result of various synthesis and lipogenesis processes induced by EtOH in the liver, were reduced by HJ. Furthermore, the activities of alcohol dehydrogenase and aldehyde dehydrogenase, enzymes linked to alcohol degradation, were more effectively downregulated by HJ treatment compared to treatment with ZR and PF alone, all without causing cytotoxic effects. Conclusions: HJ protects the liver by inhibiting EtOH-induced lipogenesis, lowering ROS generation, and improving alcohol degradation, which is more effective than ZR and PF alone. Further, in vivo experiments can offer additional evidence regarding the effectiveness, safety, and underlying mechanism of action of HJ.

• Journal of Korean Association for Spatial Structures
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• v.23 no.2
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• pp.37-44
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• 2023

In the case of a school building, even though it is a regular structure in terms of plan shape, if the masonry infill wall acts as a lateral load resisting element, it can be determined as a torsionally irregular building. As a result, the strength and ductility of the structure are reduced, which may cause additional earthquake damage to the structure. Therefore, in this study, a structure similar to a school building with torsional irregularity was selected as an example structure and the damping performance of the PC-BRB was analyzed by adjusting the eccentricity according to the amount of masonry infilled wall. As a result of nonlinear dynamic analysis after seismic reinforcement, the torsional irregularity of each floor was reduced compared to before reinforcement, and the beams and column members of the collapse level satisfied the performance level due to the reduction of shear force and the reinforcement of stiffness. The energy dissipation of PC-BRB was similar in the REC-10 ~ REC-20 analytical models with an eccentricity of 20% or less. REC-25 with an eccentricity of 25% was the largest, and it is judged that it is effective to combine and apply PC-BRB when it has an eccentricity of 25% or more to control the torsional behavior.