• Journal of Acupuncture Research
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• v.20 no.4
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• pp.42-52
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• 2003

Objective: For designing an optimal countermeasure against ageing and ageing related disease, it is necessary to understand the ageing mechanism and other reactive species. Free radicals are associated with the mechanisam of biological ageing and age-related diseases. This study was performed to identifiy the scavenging effect of Radix Cynanchi Wilfordii Herbal-Acupunture Solution(RCWHA) on Nitric Oxide(NO), 1, 1-diphenyl-2-picryl-hydrazyl(DPPH) and Interleukin-4(IL -4). Methods: The activity to scavenge DPPH radicals and NO was observed in vitro, We evaluated the antioxidant activity of RCWHA by using DPPH or NO free radical method. Also the inhibitory effect on IL-4 in RCWHA was observed in vitro, Results: The followings are the summary of the results; (1) There is a significant scavenging effect of RCWHA on NO in 0.1mg/ml and 10mg/ml group after 24hrs. (2) There is no significant scavenging effect of RCWHA on DPPH. (3) There is a significant scavenging effect of RCWHA on IL-4 in $10{\mu}g/m{\ell}$ and $100{\mu}g/m{\ell}$ group. Conclusions: These findings indicate that RCWHA can be used as antioxidant or antiimflamatory drug. But further study is needed about the effect of RCWHA.

• Journal of Haehwa Medicine
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• v.14 no.2
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• pp.177-187
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• 2005

Objective : This study is designed in order to evaluate the therapeutic effect of Scalp Acupuncture and Do-ma Acupuncture related with Governer Vessel(Dok) and Bladder Meridian(Chok-taeyang) on acute low back pain Methods : We investigated 10 patients suffering from acute low back pain were treated from Mach. 1st 2005 to Jun. 30th 2005. 10 patients, were diagnosed only straightened curvature on lateral view of lumbar spine X-ray and get Scalp acupunture related with Governer Vessel(Dok) and Bladder Meridian(Chok-taeyang) and Do-ma acupuncture. Pain rating score(PRS) was used to assess the pain for its intensity, frequency, duration, and aggravating factors. And visual analog scale(VAS) was used, too. Results : Both Scalp acupunture related with Governer Vessel(Dok) and Bladder Meridian(Chok-taeyang) and Do-ma acupuncture therapy showed good effect on acute low back pain. It was proved by the difference between PRS and VAS checked before treatment and what checked after treatment. In the evaluation of treatment effect, Exellent was 2(20%), Good was 5(50%), Moderate was 3(30%), Poor was 0(0%). Conclusion : The therapeutic effect of Scalp Acupuncture and Do-ma Acupuncture on acute low back pain can be recommended as a useful therapy to treat acute low back pain.

• Journal of Acupuncture Research
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• v.24 no.4
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• pp.25-33
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• 2007

Objective : The purpose of this study is to compare the effects of near acupuncture point needling and remote acupuncture point needling on treating ankle sprain of acute stage. Methods : From March 1st, 2007 to May 30th, 2007, the 50 patients who had visited Iksan oriental medical hospital, Wonkwang university with acute ankle sprain were divided into 2 groups ; one group took near acupunture point needling, and the other group took remote acupunture point needling. Both group had been treated with the same additional rest, ice, compression and elevation(RICE) therapy. To evaluating the efficiency of each treatment, Visual Analog Scale(VAS) and Ankle-Hindfoot Scale(AHS) were applied before 1st treatment and after 3rd treatment. Results : As a result of evaluation by using AHS, the score change comparison between the two groups had no significance after the treatment. As a result of evaluation by using VAS, treatment score of remote acupucture point needling was marked lower than score of near acupucture point needling. Conclusion : Remote acupucture point needling is more effective than near acupucture point needling in controlling the pain of acute ankle sprain.

• Journal of Korean Medicine Rehabilitation
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• v.23 no.4
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• pp.225-231
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• 2013

Objectives This study investigated the effect of korean medicine treatment with Dokhwal-tang (Duhuo-tang) on Lumbal sprain patients by comparing with other herbal medicines. Methods 17 lumbar sprain patients of group treated with Dokhwal-tang (Duhuo-tang) were treated with Dokhwal-tang (Duhuo-tang), acupunture, cupping, oriental physical therapy. 13 lumbar sprain patients of group treated with other herbal medicines were treated with 9 prescriptions of herbal medicine, acupunture, cupping, oriental physical therapy. ODI (Oswestry diability index), VAS (Visual Analogue Scale) were checked to evaluate the effectiveness of the treatment. Results 1) ODI, VAS of patients treated with Dokhwal-tang (Duhuo-tang) were all improved and there were statistical significance (p<0.05). 2) VAS of group treated with Dokhwal-tang (Duhuo-tang) and that of group treated with other herbal medicines were all improved significantly. And treatment period of group treated with Dokhwal-tang (Duhuo-tang) was shorter than that of group treated with other herbal medicines. But there was no statistical significance between VAS of group treated with Dokhwal-tang (Duhuo-tang) and that of group treated with other herbal medicines. 3) In comparing medical history period on group treated with Dokhwal-tang (Duhuo-tang), ODI, VAS of hyper-acute phase group and acute phase group were improved but them of sub-acute phase group were less improved. Conclusions According to the study, korean complex therapy with Dokhwal-tang (Duhuo-tang) might improve acute lumbar sprain.

• Journal of Physiology & Pathology in Korean Medicine
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• v.26 no.4
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• pp.432-436
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• 2012

Among a number of factors related to the effect of acupuncture and moxibustion treatment, prescriptions do important work. Traditional eastern doctors also placed emphasis on prescriptions of acupuncture and moxibustion, and a lot of experiences have been accumulated. The method forms prescriptions of Sa-am acupuncture therapy pivots on five transport points. Studies show prescriptions are made on the basis of the theory of 'Wang Xiang Xiu Qiu Si'(旺相休囚死) used engendering and restraining of five phases, and it is considered the principle of transformed prescriptions through this theory. Because there is still no study analyzing prescriptions of Sa-am acupuncture by existing principles, we report opinion about Combination principle of points in them. 1. We studied history of acupuncture and moxibustion, development and kinds of points' Combination principle. 2. Around Combination principles of points in Classic of Difficult Issues and Internal Classic, we analyzed and compared between Combination principles of points in Sa-am acupuncture therapy and them in Korea and overall acupuncture methods. 1. There were many Combination principles of acupunture point combination in Classic of Difficult Issues, Internal Classic and Korea acupuncture methods. For example, Point combination of the same meridian, Point combination of the different meridian, Exterior-Interior point combination, Point combination of the same name meridian, Point combination of the multiple meridian, Point combination of Adjacent and Distant points, Left-Right point combination, Anterior-Posterior point combination, Superior-Inferior point combination, Brook point and Stream point combination, Triple energizer point combination, Eight meeting point combination, Five transport point combination, Source-Connecting point combination, Alram point and Transport point combination, Mother-Sun meridian combination, Empirical point combination, Important point combination, Point combination according to syndrome. 2. Existing Combination principles of points in prescriptions of Sa-am acupuncture therapy included every rule. 3. They could be evidences that prescriptions of Sa-am acupuncture therapy are forms inheriting and developing acupuncture and moxibustion treatments.

• Korean Journal of Acupuncture
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• v.21 no.2
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• pp.177-192
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• 2004

Objectives : This study is designed to investigate the pathology, acupuncture and moxibustion therapy applicable of the dementia through literature of oriental medicine. Results : The findings of this study are as follows ; 1. The cause of dementia is internal damage of seven emotions(七情內傷), deficiency of the kidney essence(腎精不足), retention of dampness in the mental(痰迷心竅). 2. The acupuncture meridians used often for dementia are $Tok-maek(GV),\;Chok-t'aeyang\;Pang-gwang-Ky\check{o}ng(BL),\;Chok-yangm\check{o}yng\;Wi-Ky\check{o}ng(ST),\;Su-gwor\check{u}m\;Shimp'o-Ky\check{o}ng(PC),\;Su-so\check{u}m\;Shim-Ky\check{o}ng(HT)$. 3. The spots on the body suiTable for acupuncture used for therapy of the dementia are 98 points and extra points are 6 points, total therapeutic acupunture points are 104 points. And acupunture points are frequently used Shinmun(神門-HT7, 24), Paek'oe(百會-GV20, 19), Chok-samni(足三里-ST36, 18), Sugu(水溝-GV26, 17), P'ungnyung(豊隆-ST40, 16), Taech'u(大椎-GV14, 14), $Sam\check{u}mgyo(三陰交-SP6,\;14)$, Shimsu(心兪-BL15, 14), $Taen\check{u}ng(大陵-PC7,\;11)$, Nogung(勞宮-PC8, 11), Sosang(少商-LU11, 10), Kansa(間使-PC5, 10), Naegwan(內關-PC6, 10). 4. The acupoints used often on moxibustion are Paek'oe(百會-GV20), Chang-gang(長强-GV1), Taech'u(大椎-GV14), Kansa(間使-PC5). Conclusion : It is recommended that further study of many sided investigations in the future.

• Journal of Pharmacopuncture
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• v.4 no.1
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• pp.103-104
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• 2001

This study was done to observe the effect on the local thermal changes of herbal acupuncture on D.I.T.I.. The objects of this study are as follows; If there are remarkable local thermal changes between pre and post herbal acupuncture therapy on D.I.T.I.or not. If there are those, We examine how long that changes are maintained, what the adequate interval is on herbal acupuncture therapy, and what the reaction in a .local or whole body are on that therapy Materials and Methods : To study the local thermal changes in herbal acupuncture therapy, D.I.T.I. was used. Determination of this analysis periods are pre and post-therapy(1 hour, 24hours, 48hours and 7days later). The study group was divided into three groups(comprised 23 students in oriental medical college, Woosuk University). One was NS(Normal Saline) group, another was CF(CARTHAMI SEMEN) group and the other was BU(FEL URSI + BENZOAR BOVIS) group. The Herbal Acupunture solution was injected 0.2ml divide into 0.05ml at tile P'ungmun(B12), P'yesu(B13), Pubun(B41), Paek'o(B42) 4 points. Then, in order to analyze the clinical form, we have observed response of 23 students whenever we checked the thermal changes of their after perfoming Results : The results were obtained as follows ; 1. There is no significant dermatothermal changes at NS group and CF group, but BU group have remarkable changes in 24, 48, 72 hours. 2. From post-therapy 1 hour to 48 hours, there is a significant change (P<0.01) at NS-BU group and CF-BU group, But there is none 7 days later. 3. In the analysis of whole or local body reaction, local pain appears at NS group(22%), CF group(11%), BU group(91%), discomfort reaction appears at CF group(14%), BU group(30%). BU groilp has feel vertigo(13%), drowsy (70%) and pain in action(52%). 4. In the analysis of the duration of physic진 reaction, BU group is most lately maintained. Conclusions : These results suggest that in the physical reaction of herbal acupuncture solutions, BU solution is more sensitive than CF solution or NS.

• Korean Journal of Acupuncture
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• v.17 no.1
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• pp.11-17
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• 2000

Induction of phase II enzymes such as quinone reductase (QR) or glutathione S-transferase (GST) is considered a major mechanism of protection against initiation of carcingenesis. The induction of detoxification enzymes and glutathione were studied with Lonicerae Flos aqua-acupuncture solution (LFAS), Angelicae gigantis Radix aqua-acupuncture solution (AGRAS), and Gamdutang aqua-acupunture solution (GAS) in murine hepatoma cells grown in microtiter plate wells. LFAS, AGRAS and GAS were potent inducers of QR activity. LFAS was induced about 2.6-fold at concentration of $3{\times}$. AGRAS and GAS were also induced about 2.6-, 1.8-fold at concentration of $5{\times}$, respectively. In addition, GST activity was increased with LFAS, AGRAS, and GAS. GSH levels were increased about 2-fold with LFAS at concentration of $5{\times}$, 1.3-fold with AGRAS at concentration of $3{\times}$, and 1.2-fold with GAS at concentration of $5{\times}$. These results suggested that LFAS, AGRAS, and GAS may act as blocking agents against carcinogenesis by induction of phase II marker enzymes.

• Korean Journal of Acupuncture
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• v.24 no.3
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• pp.117-137
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• 2007

Objectives & Methods : The purpose of this study is to observe the effects of Gentianae macrophyllase Radix herbal-acupuncture solution(GR-HAS) at Joksamni(ST36) on Collagen-induced arthritis(CIA) in DBA/1J mice. The author performed several experimental items to analyze arthritis evaluation, change of weight, spleen size and adhesion rate, change of cytokine level, IgG, IgM and anti-collagen II , change of immunocyte count, histological change of CIA mouse joint related with RA. Results : 1. In the GR-HA group, the arthritis index, the incidence of arthritis and joint edema were significantly decreased. 2. In GR-HA group, there were no weight loss and similarly maintained as normal group. Spleen size, adhesion rate and the edema and transformation of knee joint were low and similarly maintained as normal group. 3. In the GR-HA, cytokine level, IgG, IgM and anti-collagen II were significantly decreased. 4. In the GR-HA, the change of immunocyte count were similarly maintained as normal group. 5. In the histological changes of the CIA mouse joint, the cartilage destruction and synovial cell proliferation were decreased in the GR-HA(Hematoxylin and eosin stain). The collagen fiber expressions in the GR-HA were similar with that of the normal group(Masson's Trichrome stain) Conclusions : These results suggest that GR-HA at ST36 has an effect to control immune reaction and suppress inflammation, synovial cell proliferation and cartilage destruction in rheumatoid arthritis.

• Journal of Pharmacopuncture
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• v.10 no.2 s.23
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• pp.25-30
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• 2007

Objectives : Free radical metabolism seems to occupy a remarkably common position in the mechanisms of aging and aging related disease. Oxidative damage to DNA, lipids. proteins and other molecules may contribute to the development of cancer, cardiovascular disease and possibly neurodegenerative disease. This study was designed to find out whether Carthami Flos Herbal-Acupuncture Solution can scavenge Nitric Oxide(NO) or not. SNAP is NO generator. NO concentration was estimated after 2,6, 12 and 24 hrs in no treatment group, after treatment with Vit. C or 1, 10, 100${\mu}$g/m1 of Carthami Flos Herbal-Acupuncture Solution. There was no significant scavenging effect of Carthami Flos Herbal-Acupuncture Solutionon NO after 2 hrs. But there was a significant scavenging effect of Cafhami Flos Herbal-Acupuncture Solution on NO in 10${\mu}$/m1 group after 6hrs. And there was a significant scavenging effect of carthami Flos Herbal-Acupuncture Solution on NO in 1, 10${\mu}$g/ml group after 12, 24 hrs. These results suggest that Carhami Flos Herbal-Acupuncture Solution has scavenging effect on NO. This study shows that Carthami Flos Herbal-Acupuncture Solution can be used for aging related disease and further studies are required to investigate the antioxidative effects of it.