• The Journal of Churna Manual Medicine for Spine and Nerves
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• v.14 no.1
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• pp.61-76
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• 2019

Objectives : The purpose of this study was to report the clinical results of various medical methods (including Chuna joint mobilization) used to treat a single patient with polyneuritis. Methods : We treated a 46 year-old female patient diagnosed with polyneuritis using various methods, including acupuncture, moxibustion, infrared therapy, herbal medication, Western medication, Chuna manual therapy, and physical therapy. We evaluated the results using the numeric rating scale (NRS), manual muscle test (MMT), active range of motion (ROM), modified barthel index (MBI). Other evaluation scale included Deep tendon reflex and thickness of muscle especially forearm and lower leg. Results : Following treatment using a combination of the above methods, the general overall condition of the patients was significantly improved. Furthermore, the NRS, MMT, MBI, and the active ROM scores were numerically improved. Conclusions : In this case, a single patient with polyneuritis was treated using a combination of Korean and Western medical methods. Although this study provides useful insight into treatment methods, further studies are required to determine the treatment effects of Korean medicine, specifically Chuna manual therapy, in patients with polyneuritis.

• The Journal of Korean Medicine Ophthalmology and Otolaryngology and Dermatology
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• v.32 no.1
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• pp.74-82
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• 2019

Objective : The purpose of this study is to analyze the trends of allergic rhinitis related articles that have been published in the Journal of Korean Medicine Ophthalmology, Otolaryngology & Dermatology(JKOOD). Method : We studied 32 articles of allergic rhinitis published in JKOOD from 1988 to 2018. 24 articles are classified into two categories; treatment-related article and diagnosis-related article which include pattern identification. And we reviewed the other 8 articles briefly in discussion. Results : 16 treatment articles are classified into two categories; 13 case reports and 3 retrospective observation studies. In case reports, the studies are classified into three categories; 3 acupuncture group, 3 herbal medicine group or 7 herbal medicine with other parallel treatments group. Conclusions : Further studies are needed on allergic rhinitis including treatment, alternative medicine and methods of evaluation in order to develop a level of evidence.

• Herbal Formula Science
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• v.30 no.4
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• pp.363-373
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• 2022

Objectives : The purpose of this study is to report one case of Korean medical treatment on a patient with psoriasis which had deteriorated since COVID-19 mRNA vaccination. Methods : A patient with psoriasis was treated with herbal medicine, acupuncture, and moxibustion. Symptoms after vaccination were considered the main criteria for treatment. PASI, DLQI, VAS, and pictures were used as evaluation tools for psoriasis. Results : After treatment, the patient showed improvements in PASI, DLQI and VAS scores. PASI changed from 16 to 0, DLQI changed from 17 to 0, and VAS changed from 8 to 0. Conclusions : The findings of this case report suggest that Korean medicine may be an effective option for treating psoriasis after COVID-19 mRNA vaccination.

• Journal of Pharmacopuncture
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• v.25 no.3
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• pp.290-300
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• 2022

Objectives: This study was conducted to evaluate the safety of SU-Eohyeol pharmacopuncture (SUEP) by assessing its potential to cause chromosomal abnormalities in Chinese hamster lung cells (CHL/IC). Methods: A dose-curve was conducted to determine the highest dose of SUEP. Doses of 10, 5, 2.5, 1.25, 0.625, and 0.313% were used, and no cytotoxicity or SUEP precipitation was observed. SUEP doses of 10, 5, and 2.5%, with positive and negative controls, were used in a chromosome aberration test. Results: In this study, the frequency of abnormal chromosomal cells in the SUEP group did not show a statistically significant difference from that of the negative control group in short-term treatments with and without metabolic activation and the continuous treatment without metabolic activation. Compared with the negative control group, the positive control group had a significantly higher frequency of cells with structural chromosomal abnormalities. This test's results satisfied all conditions for determining the results. Conclusion: SUEP did not induce chromosomal aberrations under the conditions of this study. Other toxicity evaluations, safety studies in humans, and various clinical trials are required to evaluate the safety and efficacy of SUEP.

• The Journal of Korean Medicine
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• v.44 no.2
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• pp.70-105
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• 2023

This study was conducted to examine the current status of traditional korean medicine studies on gastroesophageal reflux disease in Korea, identify deficiencies, and suggest the direction of future medicine research methods to lay the foundation for traditional korean medicine treatment. All domestic papers on the korean traditional treatment of gastroesophageal reflux disease were selected among the literature published until August 2022 in six domestic databases. A total of 52 selected research data were classified into experimental research papers, clinical research papers, and review papers. In experimental papers, to evaluate the effectiveness of treatment, improvement of esophageal mucosal lesions, anti-inflammatory mechanisms, antioxidant mechanisms, esophageal mucosal protection mechanisms, gastric peristalsis control, and gastric acid secretion inhibition mechanisms were used as evaluation measures. In the clinical research paper, the basis for diagnosis of cases was clinical symptoms through medical history listening and diagnosis through visits to hospitals in the past. The average treatment period was 40.7 days, and the duration of treatment was not significantly affected by the duration of the disease. The most widely used Korean medicine treatment intervention was herbal medicine. There were 3 literature review studies, 3 systematic literature review and meta-analysis studies, 1 comparative review study for clinical trial guideline development, all using Chinese papers. This study included all domestic papers on gastroesophageal reflux disease to identify the research trend of the Korean oriental medicine community, and based on this, it is meaningful to confirm areas that need to be supplemented in future research plans.

• Journal of Korean Medicine Rehabilitation
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• v.33 no.4
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• pp.157-165
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• 2023

Objectives The purpose of this study was to analyze trends in traditional Chinese treatment of medial tibial stress syndrome (MTSS) and suggest directions for future research in Korea. Methods We investigated clinical studies using traditional Chinese medicine for treatment of MTSS through China National Knowledge Infrastructure search. Fourteen studies published from 2000 to 2022 were adopted and analyzed. We examined authors, type of study design, publishied year, intervention, treatment effectiveness. Results Among 14 studies, 8 were case reports and 6 were randomized controlled trials. Four interventions were used in 14 studies. Acupuncture and physical therapy were most frequently used interventions, each used in 12 studies. For evaluation of treatment effectness, 7 outcome measurements were used, effective rate was the most commonly used measurement. All of 14 studies showed good treatment results. Conclusions Through this study, we were able to identify current trends of Chinese medicine treatment for MTSS. Based on this, more study should be conducted to accumulate evidence for Korean medicine treatment of MTSS.

• Journal of Oriental Neuropsychiatry
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• v.34 no.4
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• pp.453-461
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• 2023

Objectives: Major depressive disorder is a severe disease that is associated with suicidal ideation and behavior. In this case, Korean medicine psychotherapy and Korean medicine treatment were used to treat an adolescent patient with major depressive disorder. Methods: The Beck Depression Inventory, Reynolds Suicidal Ideation Questionnaire, and Crisis Triage Rating Scale were used as psychological evaluation scales. Korean medicine psychotherapy focuses on Giungoroen-therapy and IiGyeungByunQi-therapy and Korean medicine treatment combined with acupuncture, moxa, and herbal medicine. Results: Comparison before and after treatment showed improvement in clinical symptoms, Beck Depression Inventory, Reynolds Suicidal Ideation Questionnaire, and Crisis Triage Rating Scale. Conclusions: As a result of applying Korean medicine, psychotherapy and Korean medicine treatment reduces to an adolescent patient with major depressive disorder, depression, suicidal thoughts, and suicidal behavior.

• Journal of Pharmacopuncture
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• v.26 no.4
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• pp.366-372
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• 2023

Objectives: We aimed to evaluate the genotoxicity of a recently developed no-pain pharmacopuncture (NPP) targeting muscle relaxation and analgesia using the micronucleus test. Methods: To evaluate the potential of NPP extracts to induce micronuclei in rat bone marrow cells, a micronucleus test was performed using male Sprague-Dawley rats. The test substance NPP was administered intramuscularly at concentrations of 0.25, 0.5, and 1 mL/animal. Saline was used as the negative control and cyclophosphamide as the positive control. Results: No NPP treatment-related deaths or abnormal changes in general appearance were observed at any dose level during the experimental period. No statistically significant differences in body weight were observed in any of the NPP dose groups compared to the saline negative control group. NPP did not cause a significant increase in the incidence of micronucleated polychromatic erythrocytes (PCEs) and PCEs or in the ratio of PCE-to-total erythrocytes. Conclusion: The NPP extract did not exhibit genotoxic in Sprague-Dawley rat bone marrow cells under the conditions of this study. Further toxicity studies of the NPP extract are required.

• The Journal of Korean Medicine Ophthalmology and Otolaryngology and Dermatology
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• v.37 no.1
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• pp.97-106
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• 2024

Objectives : The purpose of this study is to report the effect of Bangpoongtongseong-san Gagam and Yukmijihwang-tang Gagam on whole-body xerotic eczema. Methods : We treated a 63-year-old male patient who has whole-body xerotic eczema by Korean medicine. He was treated from August 23rd, 2023 to November 22th, 2023. The treatment applied was acupuncture, pharmacopuncture and herbal medicine including 'Bangpoongtongseong-san Gagam' and 'Yukmijihwang-tang Gagam'. The evaluation was conducted by photo comparison, Visual Analogue Scale(VAS) and Dermatology Life Quality Index(DLQI). Results : After three months of treatment, the symptoms were disappeared. The itching and heat sensation decreased, and redness also disappeared. VAS of discomfort was decreased from 10 to 0. DLQI was also decreased. Conclusions : Bangpoongtongseong-san Gagam and Yukmijihwang-tang Gagam helped to relieve the itching and heat of whole-body xerotic eczema.

• Journal of Oriental Neuropsychiatry
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• v.28 no.3
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• pp.263-274
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• 2017

Objectives: To identify the current status of Korean medical practice pattern, diagnosis and treatment of dementia through recognition survey, and to use it as a preliminary data for various dementia research. Methods: Questionnaires were developed through expert meetings. The disease was defined as dementia and mild cognitive impairment, and areas were designated to practice pattern, diagnosis and treatment. From December 18, 2016-January 18, 2017, 221 respondents, including 36 neuropsychiatrists of Korean Medicine and 185 general physicians (including other medical specialists) were included. Results: 1. In both groups, the most commonly used KCD (Korean standard classification of disease and cause of death) were in the order of Unspecified Alzheimer's Dementia (F00.9), Mild Cognitive Impairment (F06.7), and Unspecified Dementia (F03). 2. The most commonly used pattern identification were zang-fu and qi-blood-yin-yang in both groups. 3. Diagnostic evaluation tools were mainly conducted by MMSE, radiologic examination, K-DRS, GDS and CDR in both groups. 4. Both groups reported using acupuncture and herbal medicine mainly. 5. In both groups, the acupuncture method was used extensively in the order of Body, Scalp, and Sa-Am. 6. Neuropsychiatrists used a variety of herbal medicines such as Wonjiseokchangpo-san (Yuanzhushichangpu-san), Yukmijihwang-tang (Liuweidihuang-tang), Palmijihwang-won (Baweidihuang-won), Sunghyangjungki-san (Xingxiang Zhengqi-san) and Ondam-tanggami (Wendan-tangjiawei). General physicians used a variety of herbal medicines such as Ondam-tanggami (Wendan-tangjiawei), Bojungikgi-tang (Buzhongyiqi-tang), Yukmijihwang-tang (Liuweidihuang-tang). 7. Neuropsychiatrists used a variety of Korean herbal preparation products (benefit and non-benefit) such as Ekgan-sangajinpibanha (Yigan-sanjiachenpibanxia), Yukmijihwang-tang (Liuweidihuang-tang), Jodeung-san (houteng-san), Palmijihwang-won (Baweidihuang-won). General physicians used a variety of Korean herbal preparation products such as Bojungikgi-tang (Buzhongyiqi-tang), Banhabaegchulcheonma-tang (banxiabaizhutianma-tang), Yukmijihwang-tang (Liuweidihuang-tang), Ekgan-sangajinpibanha (Yigan-sanjiachenpibanxia), Palmijihwang-won (Baweidihuang-won). Conclusions: By confirming awareness of Korean medical doctors treating dementia in clinical fields and understanding differences between neuropsychiatrists of Korean medicine and general physicians, it can be used to understand guideline users' needs and confirm clinical questions during development of future clinical practice guidelines for dementia.