• 혜화의학회지
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• 제16권2호
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• pp.211-216
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• 2007

Objective : This study is designed to find out the effects of indirect moxibustion at Geogol (LI16) on the shoulder pain. Methods : The patients were hospitalized Donghwa oriental medical clinic from 19th Sep. 2006 to 4th Oct. 2006, and treated with indirect moxibution at Geogol (LI16) on the shoulder pain. Results : 1. The effects of treatment by duration was follow : Below 1 month duration was improved highly. 2. The effects of treatment by condition of patients was follow : After treatment, the percentage of above "Good" level was 81%. 3. The effects of treatment by pain region of Meridian part. was follow : pain region of LI(手陽明大腸經) Meridian part was improved highly. Conclusion : According to the results, indirect moxibustion at Geogol (LI16) may be good effects on the shoulder pain.

• Korean Journal of Acupuncture
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• 제25권4호
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• pp.73-88
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• 2008

Objective : The aim of this research was to investigate the effect on five element constitutional acupuncture(Sa-am acupuncture) at 4 acupoints by needle manipulation to sedate Six Fu-Organ on hyperlipidemia induced by high fat diet in rats. Method : We recorded data of weight gain, food intake, food efficiency, weight of liver, heart, spleen, lung, kidney, levels of total cholesterol, triglyceride, HDL-cholesterol, AST, ALT in serum of rats fed high fat diet for 5 weeks. Spraque Dawley rats were divided into eight groups(normal; normal diet and non-acupuncture group, control; non-acupuncture group, Acu-LI; acupuncture at $SI_5{\cdot}LI_5{\cdot}BL_{66}{\cdot}LI_2$ group, Acu-ST; acupuncture at $GB_{41}{\cdot}ST_{43}{\cdot}LI_1{\cdot}ST_{45}$, Acu-SI; acupuncture at $BL_{66}{\cdot}SI_2{\cdot}ST_{36}{\cdot}SI_8$, Acu-BL; acupuncture therapy at $ST_{36}{\cdot}BL_{40}{\cdot}GB_{41}{\cdot}BL_{65}$, Acu-TE; acupuncture at $BL_{66}{\cdot}TE_2{\cdot}ST_{36}{\cdot}TE_{10}$, Acu-GB; acupuncture at $LI_1{\cdot}GB_{44}{\cdot}SI_5{\cdot}GB_{38}$. After needles inserted, it was rotated clockwise and anticlockwise 12 times on rats fed high fat diet. Results : The body weight was decreased in Acu-SI, Acu-TE, Acu-GB group, /the food intake was decreased in Acu-TE, / the food efficiency was decreased in Acu-SI, /serum triglyceride was decreased in Acu-LI, Acu-ST, Acu-BL, Acu-GB, /serum total cholesterol was decreased in Acu-LI, Acu-BL, serum ALP was decreased in Acu-LI, Acu-ST, Acu-BL, Acu-TE, Acu-GB. While the relative weight of heart was increased in Acu-LI, Acu-SI, the relative weight of kidney was increased in Acu-SI, Acu-GB. Conclusion : These results suggest that five element constitutional acupuncture(Sa-am acupuncture) may be having an therapeutic influence on hyperlipidemia induced by high fat diet. Further researches of acupuncture manipulation are needed in the future based on our study.

• Korean Journal of Acupuncture
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• 제24권1호
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• pp.79-94
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• 2007

Objectives : Ulcerative colitis and Crohn's disease are chronic inflammatory disease of the gastrointestinal tract was identified mainly for diarrhea, stomachache, hemafecia. The source and pathologic mechanism about ulcerative colitis and crohn's disease are still unknown but stress, infection, a genetic factor, environmental factors etc. may be the cause of chronic inflammatory disease of the gastrointestinal tract recently. The purpose of the present study is to evaluate the effects of herbal acupuncture with Artemisiae Argyi for the treatment to intestinal disease in the rat with 2, 4, 6 - trinitrobenzenesulfonic acid (TNBS) induced colitis. Methods : Artemisiae Argyi Herbal acupunctures were infected in HapGok (LI4) which is used to treat for intestinal disease in clinic. All animals were subjected to the injection of saline (300 ${\mu}l$, 500 ${\mu}l$) for a study control and TNBS (300 ${\mu}l$, 500 ${\mu}l$) into the lumen of the colon, 8cm proximal to the anus through the intestine. Artemisiae Agryi' Herbal (20 mg/ml, 0.4 ml) acupunctures were injected to the LI4 (both hands) at the secondary injection time of TNBS in rats. And body weight, RBC count, WBC count, total protein, Paw edema rate, rate of protein leakage into CMC-pouch fluid, IgG levels and IgM levels were observed to study the effects of Artemisiae Argyi' Herbal acupuncture in HapGok (Ll4). Results : Artemisiae Argyi' Herbal acupuncture in HapGok (Ll4) on TNBS-induced colitis inhibit the body weight lose rate but not RBC and WBC count. Furthermore, it inhibited the reduction of total protein concentration, paw edema, rate of protein leakage into CMC-pouch fluid, IgG levels and IgM levels. Conclusions : Herbal acupuncture with Artemisiae Argyi helps recover the TNBS-induced colonic damage and may be an important method for treatment of the colitis.

• 한국임상수의학회지
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• 제19권2호
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• pp.207-210
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• 2002

The effects of electroacupuncture on gastric motility in dogs were investigated in this study. The acupoints used in this experiment were Zu San Li (ST-36), Feng Long (ST-40), Jie Xi (ST-41), and Li Dui (ST-45) which belong to stomach meridian, Wei Shu (BL-21) which belongs to urinary bladder meridian, and Zhong Wan (CV-12) which belongs to conception vessel meridian. The animals were stimulated with 2-4 volt and 5 Hz for 20 min. Electroacupuncture at Zu San Li and Wei Shu acupoint increased the gastric motility, but Zhong Wan decreased the motility. There were no change in gastric movement after electrostimulation at Feng Long, Jie Xi and Li Dui acupoints. It was considered that electroacupuncture at Zu San Li and Wei Shu acupoints to promote the gastric movement, and at Zhong Wan acupoint to depress the movement might be effective in veterinary practice.

• Korean Journal of Acupuncture
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• 제26권2호
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• pp.91-108
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• 2009

Objectives: Single colorectal instillation of trinitrobenzenesulphonic acid (TNBS) causes a dose-dependent increase of visceral motor response (VMR) and severity of inflammation. In this study we compared the effects of electroacupuncture in the different acupoints in the acute colitis induced by TNBS intracolonic injection in rats. Methods: In Male Sprague-Dawley rats, weighing $250{\sim}400g$, a single colorectal administration of TNBS 5mg/kg and 50% ethanol under isoflurane anaesthesia after an overnight fast. Electrodes for electromyography (EMG) recording were stitched into the external oblique musculature under general anesthesia. Acupoints of LI4, ST25, or ST36 were stimulated by electroacupuncture, respectively. The balloon was inserted intra-anally and visceral motor response (VMR) to colorectal distensioin (CRD) was quantified with an EMG recording system. Results: At an observation of the visceral hyperalgesia in the day-time series, the visceromotor response increased significantly 3 days after TNBS intra-rectalcolonic injection in rats. Electroacupuncture on either ST25 or ST36 suppressed the visceromotor response to colorectal distension, but not LI4, at 3 days after TNBS injection. Pretreatment of naltrexone (10 mg/kg, i.p.), opioids antagonist, inhibited the VMR suppress of 10Hz EA to ST36 but not phentolamine (5 mg/kg, i.p.). Pretreatment of either naltrexone or phentolamine inhibited effects of 10Hz EA to ST25. Conclusions: Data show that EA at either ST25 or ST36 potently inhibits hypersensitivity of colorectum after TNBS induced colitis and is differently mediated through the endogenous opioid system and adrenergic system.

• Korean Journal of Acupuncture
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• 제25권4호
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• pp.133-145
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• 2008

Objectives : The purpose of this study was to exam the effectiveness of acupuncture using the tonification & sedation manipulation for LI4(Hegu) and KI7(Fuliu) which was known to promote sweating for lack sweating and inhibit for excessive sweating. Methods : The subject of this study was 60 people who agreed with participating. The participants were divided into 6 groups as control group without acupuncture, acupuncture group with needle inserted perpendicularly at LI4, KI7 without manipulation(AT-A), acupuncture group with needle inserted and twisted at LI4 using sedation technique and KI7 using tonificaton technique(AT-B), acupuncture group with needle inserted and twisted at LI4 using tonificaton technique and KI7 using sedation technique(AT-C), acupuncture group with needle inserted and twisted at LI4 and KI7 using tonificaton technique(AT-D) and acupuncture group with needle inserted and twisted at LI4 and KI7 using sedation technique(AT-E). We obtained baseline data at a stable condition with the temperature of $25^{\circ}C$. After having the participant stay at $40^{\circ}C$ for 10 minute and treated with acupuncture for 10 minute, we measured the parameters such as sweating rate, water content in subcutaneous, water content in skin surface, systolic blood pressure, diastolic blood pressure, pulse rate, oxygen saturation and body temperature. Results : After the tonification & sedation manipulation at LI4 and KI7, the sweating rate was significantly decreased in AT-B, AT-D and AT-E groups. The water contents in skin surface was significantly decreased in AT-B and AT-E groups. The water contents in subcutaneous was significantly decreased in AT-B, AT-C, AT-D and AT-E groups. However, there were no significant changes in systolic blood pressure, diastolic blood pressure, pulse rate, oxygen saturation and body temperature. Conclusions : Acupuncture at LI4 and KI7 is effective in controling sweating, and the effect varies according to the tonification & sedation manipulation technique.

• Korean Journal of Acupuncture
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• 제30권3호
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• pp.145-150
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• 2013

목적 : 본 연구는 코카인 연구에 사용된 경혈을 고찰하고 그 효능을 경락학설의 관점에서 해석하기 위해 수행되었다. 방법 : 논문 검색 사이트 PubMed에서 50 개의 논문, KISS에서 16 개의 논문, OASIS에서 9 개의 논문, NDSL에서 40 개의 논문, DBPIA에서 19 개의 논문을 '코카인' 또는 '침'을 검색어로 하여 조사하였다. 영문로 작성된 코카인(남용, 의존, 민감화, 섭취, 금단 증상, 재발, 탐닉)에 관한 논문을 조사하였고 수기침이나 전침만을 대상으로 하였으며 이침은 제외하였다. 결과 : 가장 많이 이용된 경혈은 신문(HT7)이었고 합곡(LI4), 태연(LU9), 족삼리(ST36), 삼음교(SP6) 등은 한 번씩 사용되었다. 신문은 수소음심경이 뇌의 기능과 깊이 관련되어 있다는 것 및 혈명이 가지는 뜻으로부터 충분히 이해될 수 있으며 태연은 신문의 효능을 증강시키는 것으로 생각된다. 합곡은 머리 꼭대기로 흐르는 궐음경을 조절하는 것으로 생각되고 족삼리는 궐음과 관련된 스트레스 반응을 조절하는 것으로 보이며 삼음교는 정신질환에 효능이 있으므로 뇌 기능을 조절하기 위해 사용된 것으로 생각된다. 결론 : 코카인 연구에 사용된 경혈은 다양한 경로를 통해 뇌 기능에 영향을 주는 것으로 사료되며 장부상통 이론이 일정 부분 관련되어 있는 것으로 생각된다.

• Korean Journal of Acupuncture
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• 제21권1호
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• pp.175-199
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• 2004

Objectives : To study acupuncture and moxibution treatments for stomatopathy( aphthae, oral ulceration, mycolic stomatitis, halitosis, thirst, bitter) the ancient and the present literatures were reviewed. Methods : We've got compared and analyzed 55 kinds of literatures. Results and Conclusions : 1. The acupuncture meridians used frequently for stomatopathy were $Su-yangmy\bar{o}ng-Taejang-ky\bar{o}ng(LI),\;Chok-yangmy\bar{o}ng-Wi-Ky\bar{o}ng(S),\;Immaek-Ky\bar{o}ng(CV)$. 2. The acupoints used frequently for aphthae were $Sungjang(CV_{24}),\;Yomchon(CV_{23}),\;Hapkok(LI_4),\;Nogung(P_8),\;Chok-samni(S_{36}),\;Hyopko(S_6),\;Sugu(GV_{26})$. 3. The acupoints used frequently for oral ulceration were $Hapkok(LI_4),\;Nogung(P_8),\;Chok-samni(S_{36}),\;Kokchi(LI_{11}),\;Sotaek(SI_1),\;Pisu(B_{20}),\;Wisu(B_{21}),\;Samgan(LI_3),\;Yomchon(CV_{23}),\;Chichang(S_4)$. 4. The acupoints used frequently for mycolic stomatitis were $Hapkok(L_4),\;Chichang(S_4),\;Hyopko\;(LI_4),\;Sungjang(CV_{24}),\;Samumgyo(SP_6)$. 5. The acupoints used frequently for halitosis were $Naejong(S_{44}),\;Chok-samni(S_{36}),\;Chung-wan\;(CV_{12}),\;Sang-wan(CV_{13}),\;Hawan(CV_{10}),\;Kongson(SP_4),\;Wisu(B_{21}),\;Nogung(P_8),\;Sugu(GV_{26}),\;Sungjang(CV_{24})$. 6. The acupoints used frequently for thirst were $Sosang(L_{11}),\;Sangyang(LI_1),\;Sotaek(SI_1),\;Kwanch'ung(TE_1),\;Ch'\bar{o}kt'aek(L_5),\;T'ae-gye(K_3),\;Kokt'aek(P_3),\;Sugu(GV_{26}),\;Samgan(LI_3),\;Igan(LI_2),\;T'aech'ung(Liv_3),\;Sojangsu(B_{27})$. 7. The acupoints used frequently for bitter were $Yangn\bar{u}ngch'\bar{o}n(G_{34}),\;Hy\bar{o}njong(G_{39}),\;Kwanch'ung(TE_1),\;Tamsu(B_{19}),\;Chokkyu\bar{u}m(G_{44}),\;Y\bar{o}n-gok(K_2),\;Shinmun(H_7),\;Chok-Samni(S_{36})$.

• Korean Journal of Acupuncture
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• 제38권2호
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• pp.100-109
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• 2021

Objectives : Source acupoint is one of the representative acupoints to treat various diseases in each meridian. We aimed to identify the patterns of selection of Source acupoints and their associations with diseases using clinical trials data. Methods : We extracted the frequency of Source acupoints across 30 diseases from clinical trials database. Acupuncture treatment regimens were retrieved from the Cochrane Database of Systematic Reviews. The frequency of Source acupoint use was calculated as the number of studies using a certain acupoint divided by the total number of included studies. Using hierarchical clustering and multidimensional scaling, the characteristics of Source acupoints were analyzed based on the similarity of the relationships between the Source acupoints and the diseases. Results : A total of 421 clinical trials were included for this analysis. LR3, HT7, KI3, and LI4 acupoints were most frequently used for the treatment of 30 diseases. Cluster analysis showed that LR3 and LI4 acupoints were grouped together and HT7 and KI3 acupoints were grouped together. Multidimensional scaling revealed that LR3, LI4, HT7, and KI3 acupoints have intrinsic properties in the two-dimensional space. Conclusions : The present study identified the selection patterns of the Source acupoints using clinical trials data. Our finding will provide the understanding of the characteristics of Source acupoints.

• Journal of Acupuncture Research
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• 제25권2호
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• pp.259-266
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• 2008

Objectives : To learn the effects of $CV_{12}\;{\cdot}\;CV_9$ and $LI_4\;{\cdot}\;LI_{11}$ electroacupuncture stimulation on high fat diet induced-obese mouse. Methods : The control group was provided with high fat diet without electroacupuncture stimulation, while the experimental group $CV_{12}\;{\cdot}\;CV_9$ and $LI_4\;{\cdot}\;LI_{11}$ with three frequencies(10Hz, 100Hz, 200Hz) for 5 times a week during five week periods with the high fat diet. We investigated the body weight, weight gain, and food intake. Results : After the electroacupuncture stimulation, a significant loss of increasement in weight was found in the experimental group compared with the high fat diet group. But there was no significant difference made by the change of acupoint combinations and frequencies. After the electroacupuncture stimulation, no significant change was found in the food intakes, but the weight gain a week was decreased compared with high fat diet group. Conclusions : These results suggest that electroacupuncture stimulation on $CV_{12}\;{\cdot}\;CV_9$ and $LI_4\;{\cdot}\;LI_{11}$ might be effective in treatments of obesity to high fat diet.