• 제목/요약/키워드: activity energy

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잡음 환경에서 심리음향모델 기반 음성 에너지 최대화를 이용한 음성 검출 방법 (Voice Activity Detection Method Using Psycho-Acoustic Model Based on Speech Energy Maximization in Noisy Environments)

  • 최갑근;김순협
    • 한국음향학회지
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    • 제28권5호
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    • pp.447-453
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    • 2009
  • 이 논문은 음성 에너지를 최대화 하여 낮은 SNR환경에서 음성 존재 여부를 판단하고 정확한 끝점을 검출하는 방법에 대한 것이다. 전통적인 VAD (Voice Activity Detection) 알고리듬은 잡음의 추정치를 이용해 음성과 비음성 구간을 선택하여 낮은 SNR환경이나 비안정 잡음환경에서는 정확하지 못한 문턱값으로 인해 부정확한 끝점검출을 하였다. 또한 잡음의 시간적 변화를 반영하기 위해 비교적 큰 분석 구간을 두어 계산량이 증가함에 따라 실제 응용에 적합하지 않은 단점이 있다. 이 논문은 잡음환경에서 정확한 음성 구간의 검출을 위해 심리음향 모델에 기반 한 바크 스케일 필터 뱅크를 이용하여 주어진 프레임에서 음성 에너지를 최대화 시키고 잡음을 억제하는 SEM-VAD (Speech Energy Maximization-Voice Activity Detection) 방법을 제안하였다. 다양한 잡음환경, SNR 15 dB, 10 dB 5 dB 0 dB 상황에서 실험한 결과 SNR의 변화에 안정적인 문턱값을 얻었고, 음성 검출을 위한 실험에서 자동차 잡음 환경에 대한 PHR (Pause Hit Rate)은 모든 잡음 환경에서 100%의 정확도를 보였고, FAR (False Alarm Rate)는 SNR 15 dB와 10 dB에서는 0%, SNR 5 dB에서 5.6% SNR 0 dB에서 9.5%의 성능을 보였다.

3D-QSAR of Angiotensin-Converting Enzyme Inhibitors: Functional Group Interaction Energy Descriptors for Quantitative Structure-Activity Relationships Study of ACE Inhibitors

  • Kim, Sang-Uk;Chi, Myung-Whan;Yoon, Chang-No;Sung, Ha-Chin
    • BMB Reports
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    • 제31권5호
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    • pp.459-467
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    • 1998
  • A new set of functional group interaction energy descriptors relevant to the ACE (Angiotensin-Converting Enzyme) inhibitory peptide, QSAR (Quantitative Structure Activity Relationships), is presented. The functional group interaction energies approximate the charged interactions and distances between functional groups in molecules. The effective energies of the computationally derived geometries are useful parameters for deriving 3D-QSAR models, especially in the absence of experimentally known active site conformation. ACE is a regulatory zinc protease in the renin-angiotensin system. Therapeutic inhibition of this enzyme has proven to be a very effective treatment for the management of hypertension. The non bond interaction energy values among functional groups of six-feature of ACE inhibitory peptides were used as descriptor terms and analyzed for multivariate correlation with ACE inhibition activity. The functional group interaction energy descriptors used in the regression analysis were obtained by a series of inhibitor structures derived from molecular mechanics and semi-empirical calculations. The descriptors calculated using electrostatic and steric fields from the precisely defined functional group were sufficient to explain the biological activity of inhibitor. Application of the descriptors to the inhibition of ACE indicates that the derived QSAR has good predicting ability and provides insight into the mechanism of enzyme inhibition. The method, functional group interaction energy analysis, is expected to be applicable to predict enzyme inhibitory activity of the rationally designed inhibitors.

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이트륨 함량에 따른 Pd-Ir-Y 3원계 합금 촉매 입자의 특성과 산소 환원 반응의 활성 비교 (Comparison of the Characteristics of Pd-Ir-Y Ternary Alloy Catalyst Particles and Oxygen Reduction Activity According to Yttrium Contents)

  • 김도형;이은애;박찬호
    • 한국수소및신에너지학회논문집
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    • 제29권3호
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    • pp.260-266
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    • 2018
  • To enhance catalyst activity of the palladium (Pd) towards oxygen reduction reaction (ORR), iridium (Ir) and yttrium (Y) were alloyed by polyol method. Due to the low reduction potential of Y, it is hard to reduce Y ion completely by polyol method. In XPS spectra, the binding energy of the Pd is shifted to a lower value, which indicates the d-electron of Pd is filled by the electron from the Y. And other phases of Y are observed by the XPS. Among the catalysts, the $Pd_4IrY_{0.1}/C$ showed the best activity towards ORR, which indicates the metallic Y is effective for improving the catalytic activity. Thus, for further enhancing ORR activity, the novel method for complete reduction of Y is needed.

Experimental simulation of activity release from leaking fuel rods

  • Somfai, Barbara;Hozer, Zoltan;Nagy, Imre
    • Nuclear Engineering and Technology
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    • 제50권7호
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    • pp.1148-1153
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    • 2018
  • The Leaking Fuel Experiment test facility was designed to simulate the activity release from spent leaking fuel rods under steady state and transient conditions in the spent fuel pool. The experimental rig included an electrically heated fuel rod with different defects and a cooling system. The fission product transport was simulated by potassium-chloride. The conductivity changes of the water in the cooling system were measured to provide information about the amount of released solution. Defects of different sizes and positions were applied, together with a wide range of rod powers to simulate decay heat. The produced data can be used for predicting the activity release from leaking fuel under storage conditions and for the interpretation of fuel examination procedures.

Phytochemicals and antioxidant activity in the kenaf plant (Hibiscus cannabinus L.)

  • Ryu, Jaihyunk;Kwon, Soon-Jae;Ahn, Joon-Woo;Jo, Yeong Deuk;Kim, Sang Hoon;Jeong, Sang Wook;Lee, Min Kyu;Kim, Jin-Baek;Kang, Si-Yong
    • Journal of Plant Biotechnology
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    • 제44권2호
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    • pp.191-202
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    • 2017
  • Chemical compounds from four different tissues of the kenaf plant (Hibiscus cannabinus), a valuable medicinal crop originating from Africa, were examined to determine its potential for use as a new drug material. Leaves, bark, flowers, and seeds were harvested to identify phytochemical compounds and measure antioxidant activities. Gas chromatography mass spectrometry analyses identified 22 different phytocompounds in hexane extracts of the different parts of the kenaf plant. The most abundant volatile compounds were E-phytol (32.4%), linolenic acid (47.3%), trisiloxane-1,1,1,5,5,5-hexamethyl-3,3-bis[(trimethylsilyl)oxy] (16.4%), and linoleic acid (46.4%) in leaves, bark, flowers, and seeds, respectively. Ultra-high performance liquid chromatography identified the major compounds in the different parts of the kenaf plant as kaemperitrin, caffeic acid, myricetin glycoside, and p-hydroxybenzoic acid in leaves, bark, flowers, and seeds, respectively. Water extracts of flowers, leaves, and seeds exhibited the greatest DPPH radical scavenging activity and SOD activity. Our analyses suggest that water is the optimal solvent, as it extracted the greatest quantity of functional compounds with the highest levels of antioxidant activity. These results provide valuable information for the development of environmentally friendly natural products for the pharmaceutical industry.

퇴행성 관절질환을 동반한 비만환자의 운동프로그램 개발에 대한 연구 (A Development of Exercise Program on Obese patients with Osteoarthritis)

  • 임형호;송윤경
    • 한방비만학회지
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    • 제3권1호
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    • pp.17-24
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    • 2003
  • Obesity increases the risk of knee and to a lesser extent hip OA, which combined affect a large percentage of middle-aged and elderly adults and which are major source of disability, and factor of drop a lowering in the physical exercise ability. Energy expenditure from physical activity accounts for up to 30% of total energy expenditure, it can have a significant impact on energy balance. We studied a exercise therapy that improved long-term weight management and produced additional benefits - loss of joint pain, improved joint mobility, and this exercise program will enhance the weight loss and health benefits from physical activity in the treatment of obese patients with osteoarthritis.

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초등학생(고학년)의 에너지필요추정량 산출을 위한 4단계 신체활동단계의 간편 판정법 연구 (Criterion Development of 4 Activity Levels for Estimated Energy Requirement Calculation for Primary School Students)

  • 김미정;나현주;김영남
    • 대한지역사회영양학회지
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    • 제16권3호
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    • pp.307-314
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    • 2011
  • The purpose of this study is finding the easy way of 4 categories activity level confirmation for estimated energy requirement calculation. Total of 386, 5th and 6th grade primary school students participated. The time spent on 7 kinds of activity were collected for 1 day by the internet program developed. Judged by the activity coefficient, sedentary were 6.7% and 5.1%, low active 33.2% and 40.4%, active 43.8%, and45.5%, and very active 16.3% and 9.0% for boy and girl, respectively. The highest and significant correlation coefficient between activity coefficient and time spent on activities shown were 0.339 in commute activity for boys, and 0.466 in leisure for girls. The sensitivity of the sedentary conformation by commute hour for boys was 0.79, and that of very active was 0.56. The sensitivity of the sedentary conformation by leisure hour for girls was 0.67, and that of very active was 0.63. The sensitivity of low active and active by 7 different types of activity was quite low, 0.04~0.37. The exact agreement of activity level conformed by easy way developed was 30.8% and 33.7%, for boys and girls, respectively. More accurate way to identify 4 categories activity level needs to be developed, especially sensitive to conformation of low active and active levels.

Comparison of Hydrogenases from Clostridium butyricum and Thiocapsa roseopersicina: Hydrogenases of C. butyricum and T. roseopersicina

  • Baek Jin-Sook;Choi Eun-Hye;Yun Young-Su;Kim Sun-Chang;Kim Mi-Sun
    • Journal of Microbiology and Biotechnology
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    • 제16권8호
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    • pp.1210-1215
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    • 2006
  • The properties related to the temperature and oxygen stability of the cytoplasmic hydrogenases from the fermentative strict anaerobic bacterium, Clostridium butyricum NCIB 9576 (Cl. butyricum), and purple sulfur phototrophic bacterium, Thiocapsa roseopersicina NCIB 8347 (T. roseopersicina), were compared. The optimum temperatures for the growth of Cl. butyricum and T. roseopersicina were 37$^{\circ}C$ and 25$^{\circ}C$, respectively, whereas those for the H$_2$ evolution of the cytoplasmic hydrogenases prepared from Cl. butyricum (C-H$_2$ase) and T. roseopersicina (T-H$_2$ase) were 45$^{\circ}C$ and 65$^{\circ}C$, respectively. The T-H$_2$ase was more thermostable than the C-H$_2$ase and retained its full activity for 5 h at 50$^{\circ}C$ under anaerobic conditions and 90% of its activity at 60$^{\circ}C$, whereas the C-H$_2$ase lost its activity drastically at 50$^{\circ}C$. The optimum pHs for H$_2$ oxidation of the C-H$_2$ase and T-H$_2$ase were 9.0 and 7.5, respectively. Both enzymes showed a maximum H$_2$ evolution activity at pH 7.0. Under aerobic conditions, 80% of the T-H$_2$ase activity was retained for 10 h at 30$^{\circ}C$, and 50% of the activity remained after 6 days under the same experimental conditions. However, the C-H$_2$ase was labile to oxygen and lost its activity immediately on exposure to air. Therefore, these properties of the T-H$_2$ase are expected to be advantageous for application in in vitro biological H$_2$ production systems.