• Journal of Korean Tunnelling and Underground Space Association
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• v.23 no.1
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• pp.25-36
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• 2021

Hydrogen in hydrogen-electric vehicles has a wide range of combustion and explosion ranges, and is a combustible gas with a very fast flame propagation speed, so it has the risk of leakage, diffusion, ignition, and explosion. The fuel tank has a Thermally active Pressure Relief Device (TPRD) to reduce the risk of explosion and other explosions, and in the event of an accident, hydrogen inside the tank is released outside before an explosion or fire occurs. However, if an accident occurs in a semi-closed space such as an underground parking lot, the flow of air flow is smaller than the open space, which can cause the concentration of hydrogen gas emitted from the TPRD to accumulate above the explosion limit. Therefore, in this study, the leakage rate and concentration of hydrogen over time were analyzed according to the diameter of the nozzle of the TPRD. The diameter of the nozzle was considered to be 1 mm, 2.5 mm and 5 mm, and ccording to the diameter of the nozzle, the concentration of hydrogen in the underground parking lot increases in a faster time with the diameter of the nozzle, and the maximum value is also analyzed to be larger with the diameter of the nozzle. In underground parking lots where air currents are stagnant, hydrogen concentrations above LFL (Lowe Flammability Limit) were analyzed to be distributed around the nozzle, and it was analyzed that they did not exceed UFL (Upper Flammability Limit).

• Journal of Korea Trade
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• v.24 no.4
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• pp.71-94
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• 2020

Purpose - Multi-National Enterprises (MNEs) tend to face a high level of institutional pressures in regions with high institutional development level. When complying with institutional pressures, firms try to make decisions to maximize profit while minimizing the risks to them. The purpose of this study is to investigate the influence of the institutional development level on institutional compliance timing by MNEs and the relationship between compliance speed and corporate performance. Design/methodology - The research focuses on three main variables, which are the institutional development level (as a determination of the institutional pressure level), the firm's compliance speed (as a determination of the compliance timing), and the firm's financial performance (as a determination of the corporate performance). We collected 19,869 firm-level data from CSMAR (the China Stock Market and Accounting Research), 6,922 CSR data from RKS (the Rankins CSR Ratings), and province and city-level data from the NERIM (National Economic Research Institute Index of Marketization) and NBSC (National Bureau of Statistics of China). The firms in China were chosen for analysis, and the analysis period was from 2008 to 2017. Random Effects GLS Regression was used to test the relationships among the variables. Findings - This study examined the effect of the institutional development level on the firm's compliance speed, together with the effect of compliance speed on the firm's financial performance of the MNEs in China. We found that the institutional development level positively influenced firms' financial performances, which means the firms' financial performances are better in the region with a high institutional development level. The compliance speed of institutional practice by firms was faster in the higher level of institutional development. However, the firm's delayed compliance led to better financial performance. Originality/value - Studies in the resource dependence view of Institutional Theory often fall short in understanding the theory by overlooking the firm's active decision-making. Thus, the findings do not present a full scope of corporate performance in this regard. This study not only found a way to test the role of a firm's independent decision-making (i.e., compliance timing) when facing the institutional pressure but also prove the significant role of the compliance timing on corporate performance. Also, we were able to test the effect of institutional development level, controlling location-specific variables because we used CSR performance data for MNEs operating in China. Lastly, by doing the above, the findings of this study suggest practical implications to the industry practitioners in MNEs.

• The Magazine of the Society of Air-Conditioning and Refrigerating Engineers of Korea
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• v.39 no.9
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• pp.41-51
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• 2010

건물의 배수 및 통기시스템에서 나타나는 현상중에 확실한 내용이 아직 밝혀지지 않은 부분이 몇 가지 남아 있다. 이것은 19세기 말엽의 근대 위생공학의 시작 단계에서부터 잘 알려진 사실이다. 건물의 배수 및 통기시스템 운용에 대한 내용은 일반 공학과 특정 유체역학의 범위 내에서 가장 잘 이해할 수 있다. 건물의 배수 및 통기시스템의 운영에 종사했던 초기의 기술진들은 이러한 점을 잘 알고 있었으며 유체역학에 적합하게 응용한 많은 사례를 확인할 수 있었다. 제2차 세계대전이 끝나고 이에 대한 많은 연구가 진행되어 왔으며 특히 유럽에서 시작된 전후 재건 붐을 통해 배수 및 통기시스템의 설계에 좀 더 효율적인 접근이 진척되게 되었다. 이러한 배수시스템의 중심에는 배수관 내부의 오염된 공기가 배수구 또는 위생기구를 통하여 주거 공간으로 유입되는 것을 방지하는 트랩(Water Trap)이 있다. 배수트랩의 주요 기능인 봉수는 일반적으로 깊이가 40 mm에서 50 mm 정도로 위생기구의 종류에 따라 봉수의 깊이는 다소 차이가 있다. 배수관내 공기의 흐름이 중요한 것처럼 트랩의 봉수 메커니즘이 중요하기 때문에 이 메커니즘을 소홀히 여긴다면 안전한 배수시스템의 운영을 기대하기는 어렵다. 배수관 내의 공기의 흐름은 배수에 의해 유입되거나 또는 배출된다. 배수관에서 내부 압력의 불규칙한 변화로 인하여 야기되는 불안정한 배수의 흐름은 트랩의 봉수를 파괴하고 나아가 주거공간으로 오염된 공기가 새어 나갈 수 있는 통로를 제공하게 된다. 관내압력의 천이는 이로 인한 문제가 발생할 가능성이 있는 위치에 그 압력을 완화할 수 있는 장치를 설계단계에 반영하여 적용함으로써 제어할 수 있다. 건물 내부에 상당한 길이의 통기배관을 설치하는 것은 배관의 마찰손실로 인하여 천이 현상을 효과적으로 제어할 수 있는 확실한 방법이 되지는 못한다. 그렇지만 통기밸브를 설치하는 것과 같이 배수관 내로 공기를 공급해주는 유입구를 건물 내부에 분산 설치하는 것이 효율적인 통기방식이 될 수 있고, 정압 천이로 인한 위험을 줄여줄 수 있다. 통기밸브는 정압 발생의 원인이 되지 않으며 단지 정압에 반응하여 더욱 기밀하게 닫히며, 약화된 압력파를 반사할 뿐이다. 고층 건물에서 배수입상관과 평행하게 설치된 통기입상관(Parallel Vent Pipe)의 경우 극히 일부분의 정압 천이 현상을 완화할 수 있다. (통기 배관의 직경이 배수 입상배관과 동일한 경우 대략 1/3 정도임), 그러므로 정압의 천이로 인한 압력 파동은 배수 시스템의 나머지 부분을 통해 전파되어 배수 트랩에 영향을 미치게 된다. 정압의 천이가 예상되는 위치에 정압천이 완화 장치(Positive Air Pressure Transient Alleviation Device)를 사용하면 배관 내부압력의 급격한 상승을 방지하여 연결된 트랩의 봉수를 보호할 수 있다. 이렇게 되면 순간적으로 발생하는 배관내 압력의 급등 현상을 90% 정도까지 완화 시킬 수 있다. 경험적으로 배수시스템에서 배관이 완전하게 막혀 과도한 정압이 발생하는 경우는 거의 없다. 이러한 경우에는 가장 낮은 위치에 있는 배수 트랩의 봉수가 깨지면서 자연스럽게 배수시스템의 압력이 해소되게 된다. 이러한 사례는 통기 방식과 상관없이 발생할 수 있다. 실제와 유사한 시뮬레이션을 통하여 통기 밸브(Air Admittance Valves)는 전면 통기 시스템 (Fully Vented System)에서 최소한 트랩의 봉수 보호용으로 적합한 것이 확인 되었다. 어떤 경우 에는 고층 건물에 더욱 적합하다는 것을 확인할 수 있었다. 부압 해소용으로 통기밸브를 이용하고 정압완화용으로 정압 완화장치(PAPAs: Positive Air Pressure Transient Attenuators)를 사용하는 전면적 능동 제어시스템(Fully Engineered Designed Active Control System)이 사용자에게 육안으로는 확인하지 못하는 기능을 보장하면서 배수 시스템의 안전과 효율성에 대한 효과적인 방법을 제공하고 있다.

• Journal of Life Science
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• v.33 no.10
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• pp.791-796
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• 2023

It is well known that any kind of physical activity can be a useful nonpharmacological tool in the prevention and treatment of cardiovascular diseases, including antihypertension. There is also strong evidence that suggests that people with cardiovascular disease are less active than healthy people. Therefore, the aim of this study was to investigate the effect of a 12-week walking exercise intervention program on body composition, insulin resistance, and blood pressure in obese elderly women with stage 1 hypertension. The walking exercise program was performed for 50 min, three times per week. The intensity progressively increased: RPE 11 to 12, 40-50% HRR, for weeks 1-4; RPE 12 to 13, 50-60% HRR, for weeks 5-8; and RPE 13 to 14, 60-65% HRR, for weeks 9-12. The subjects were 20 obese elderly women with stage 1 hypertension (SBP: 140-159 mmHg or DBP: 90-99 mmHg). Half were placed in the walking exercise group (EX, n=10), and half were placed in the control group (CON, n=10). At the end of the program, the EX group members had significantly lower body fat, insulin resistance, and SBP compared to the CON group members. These results suggest that undertaking a 12-week walking exercise program improves body fat, insulin resistance, and SBP, which may improve the incidence of metabolic disease in elderly obese women with stage 1 hypertension.

• Journal of the Society of Cosmetic Scientists of Korea
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• v.50 no.2
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• pp.103-110
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• 2024

Lipid nanoparticles (LNPs) are a stable and an effective system that protects cell-impermeable biologically active compounds such as nucleic acids, proteins, and peptides against degradation caused by subtle environmental changes. This study focuses on developing LNPs encapsulating gallic acid (GA), an antioxidant, to effectively prolong the half-life of tetrahexyldecyl ascorbate (THDC), a oil-soluble vitamin C derivative. These LNPs were synthesized in small, uniform sizes at room temperature and pressure conditions using a microfluidics chip. Compared to liposomes manufactured under high pressure and high temperature conditions through conventional microfluidizers, LNPs manufactured through microfluidics chips had excellent dispersion and temperature stability, and improved skin absorption as well as improved oxidative stability of fat-soluble vitamin C derivatives. Future studies will focus on ex vivo and in vivo evaluations to study skin improvement to further validate these results.

• Journal of The Korean Society of Integrative Medicine
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• v.12 no.2
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• pp.89-100
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• 2024

Purpose : The objective of this study was to determine the major factors influencing the onset of diabetes and prediabetes and for collection of the basic data required to reduce the prevalence of diabetes and plan for administration of an effective health care system. By classifying the level of blood sugar management according to three categories: normal, prediabetes, and diabetes diagnosis, and determining the causes of diabetes in consideration of various variables, we will conduct an analysis of the main factors to be addressed for effective management of blood sugar and for preparation of basic data for use in early management. Methods : In this study, an analysis of raw data from the 8th National Health and Nutrition Examination Survey collected over a period of three years from 2019 to 2021, including 8,110 subjects in 2019, 7,359 subjects in 2020, and 7,090 subjects in 2021 was performed. A total of 22,559 subjects were aged 19 years or older, and 15,821 subjects were classified as subjects for inclusion in the final analysis. In the analysis, categorical variables were tested for difference, analysis of continuous variables using regression was performed, and analysis of influencing factors was performed using multinomial logistic analysis. Result : Significant factors related to the onset of diabetes and prediabetes included age (p<.001), marital status (p<.001), occupation (p<.001), hypertension (p<.001), dyslipidemia (p<.001), cardiovascular disease (p=.008), alcohol (p=.030) smoking (p=.005), systolic blood pressure (p<.001), diastolic blood pressure (p<.001), body mass index (p<.001) and waist circumference (p=.037), blood triglycerides (p<.001), and blood cholesterol (p<.001). Conclusion : Diabetes, a complex disease affected by a variety of diseases, requires active management from the prediabetes stage, and providing an appropriate level of medical information and services to elderly individuals without family support is considered a long-term health care system requirement in Korean society where the demographic structure is changing. In particular, determining the causes of prediabetes and development of a preventive approach to administering the health care system will be important for efficient management of diabetic patients.

• Nuclear Engineering and Technology
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• v.56 no.3
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• pp.803-811
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• 2024

Nuclear accidents such as Fukushima Daiichi have highlighted the potential of passive safety systems to replace or complement active safety systems as part of the overall prevention and/or mitigation strategies. In addition, passive systems are key features of Small Modular Reactors (SMRs), for which they are becoming almost unavoidable and are part of the basic design of many reactors available in today's nuclear market. Nevertheless, their potential to significantly increase the safety of nuclear power plants still needs to be strengthened, in particular the ability of computer codes to determine their performance and reliability in industrial applications and support the safety demonstration. The PASTELS project (September 2020-February 2024), funded by the European Commission "Euratom H2020" programme, is devoted to the study of passive systems relying on natural circulation. The project focuses on two types, namely the SAfety COndenser (SACO) for the evacuation of the core residual power and the Containment Wall Condenser (CWC) for the reduction of heat and pressure in the containment vessel in case of accident. A specific design for each of these systems is being investigated in the project. Firstly, a straight vertical pool type of SACO has been implemented on the Framatome's PKL loop at Erlangen. It represents a tube bundle type heat exchanger that transfers heat from the secondary circuit to the water pool in which it is immersed by condensing the vapour generated in the steam generator. Secondly, the project relies on the CWC installed on the PASI test loop at LUT University in Finland. This facility reproduces the thermal-hydraulic behaviour of a Passive Containment Cooling System (PCCS) mainly composed of a CWC, a heat exchanger in the containment vessel connected to a water tank at atmospheric pressure outside the vessel which represents the ultimate heat sink. Several activities are carried out within the framework of the project. Different tests are conducted on these integral test facilities to produce new and relevant experimental data allowing to better characterize the physical behaviours and the performances of these systems for various thermo-hydraulic conditions. These test programmes are simulated by different codes acting at different scales, mainly system and CFD codes. New "system/CFD" coupling approaches are also considered to evaluate their potential to benefit both from the accuracy of CFD in regions where local 3D effects are dominant and system codes whose computational speed, robustness and general level of physical validation are particularly appreciated in industrial studies. In parallel, the project includes the study of single and two-phase natural circulation loops through a bibliographical study and the simulations of the PERSEO and HERO-2 experimental facilities. After a synthetic presentation of the project and its objectives, this article provides the reader with findings related to the physical analysis of the test results obtained on the PKL and PASI installations as well an overall evaluation of the capability of the different numerical tools to simulate passive systems.

• Sleep Medicine and Psychophysiology
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• v.3 no.1
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• pp.85-95
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• 1996

Obstructive sleep apnea syndrome(OSAS) in childhood is unique and different n-om that in adulthood in several aspects, including pathophysiology, clinical features, diagnostic criteria, complications, management, and prognosis. Characteristic features of childhood OSAS in comparison with the adult form are the variety of severe complications such as developmental delay, more prominent behavioral and cognitive impairments, vivid cardiovascular symptoms, and increased death risk, warranting a special attention to the possible diagnosis of OSAS in children who snore. However, the childhood OSAS is often neglected and unrecognized. We, therefore, report a case of very severe OSAS in a 5-year-old boy who was sucessfully treated with continuous positive airway pressure(CPAP) treatment. Interestingly, the patient was comor-bid with the attention deficit hyperactivity disorder. Prior to the initial visit to us, adenotonsillectomy had been done at the age of 4 with no significant improvement of apneic symptoms and heavy snoring. On the initial diagnostic procedures, marked degree of snoring was audible even in the daytime wake state and the patient was observed to be very hyperactive. Increased pulmonary vascularity with borderline cardiomegaly was noted on chest X-ray. The baseline polysomnography revealed that the patient was very sleep-apneic and snored very heavily, with the respiratory disturbance index(RDI) of 46.9 per hour of sleep, the mean SaO2 of 78.8%, and the lowest SaO2 of 40.0%(the lowest detectable oxygen level by the applied oxymeter). The second night polysomnography was done for CPAP titration and the optimal pressure turned out to be $8.0\;cmH_2O$. The applied CPAP treatment was well tolerated by the patient and was found to be very effective in alleviating heavy snoring and severe repetitive sleep apneas. After 18 months of the CPAP treatment, the patient was followed up with nocturnal polysomnography(baseline and CPAP nights) and clinical examination. Sleep apneas were still present without CPAP on the baseline night. However, the severity of OSAS was significantly decreased(RDI of 15.7, mean SaO2 of 96.2%, and the lowest SaO2 of 83.0%), compared to the initial polysomnographic findings before initiation of long-term CPAP treatment. Wechsler intelligence tests done before and after the CPAP treatment were compared with each other and surprising improvement of intelligence(total 9 points, performance 16 points) was noted. Clinically he was found to be markedly improved in his attention deficit hyperactive behavior after CPAP treatment, but with minimal change of TOVA(test of variables of attention) scores except conversion of reaction time score into normal range. On the chest X-ray taken after 18 months of CPAP application, the initial cardiopulmonary abnormalities were not found at all. We found that the CPAP treatment in a young child is very effective, safe, and well-tolerated and also improves the co-morbid attention deficit hyperactive symptoms. Overall, the growth and development of the child has been facilitated with the long-term use of CPAP. Cardiovascular complications induced by OSAS have been also normalized with CPAP treatment. We suggest that early diagnosis and active treatment intervention of OSAS in children are crucial in preventing and ameliorating possible serious complications caused by repetitive sleep apneas and consequent hypoxic damage during sleep.

• Journal of Plant Biotechnology
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• v.6 no.1
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• pp.15-19
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• 2004

The expression of a chimeric transgene (nos-npt II) has been examined in 9 years old transgenic poplars (Populus koreana x P. nigra) growing in a nursery. The expression of the gene in twenty six independentely transformed plants were examined by 1) enzyme (NPT II) assay, 2) RT-PCR, and 3) resistance to kanamycin. High NPT II activities in young leaves of all the transformed plants were found even without a selection pressure for antibiotics for 9 years. However, the activity varied with the positions of leaves in the stem in that young leaves showed higher activity than did mature tissues. When leaf segments were cultured in the presence of 150 mg/l kanamycin, only those from young leaves produced vigorously growing callus. However, as in the case of NPTII assay, the leaf segments from mature leaves did not form callus well on the media. RT-PCR with nptII specific primers also showed that amplification products were observed only when RNAs from young tissues were used. The total RNA gel showed that while RNA in young leaves are relatively stable and in a large quantity, those in old leaves were mostly degraded. All the above results suggest that the gene is transcriptionally active only in young tissue even though it is attached to a constituitive promoter. Therefore, the expression of foreign gene in poplar plants seemed to be affected by the metabolic state of the cells and thus vary greatly with the developmental stages and the age of tissue.

• Journal of the Korean institute of surface engineering
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• v.34 no.5
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• pp.465-474
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• 2001

Type 304SS coatings were performed at 200$\square$ onto AISI 1045 carbon steel substrate using unbalanced magnetron sputtering (UBMS) with an austenitic AISI 304 stainless steel (SS) target of 100mm diameter. The total deposition pressure in the active Ar gas was 2$\times$10$^{-3}$ Torr. Coatings were done at various target power densities and bias voltages. Chemical compositions of metallic elements of the coatings were measured by energy dispersive X-rays spectroscopy (EDS). The structure and the morphology of Type 304SS coatings were investigated by means of X-ray diffraction (XRD) and scanning electron microscopy (SEM). Corrosion properties of the coated specimens were examined using electrochemical polarization measurements and electrochemical impedance spectroscopy in a deaerated 3.5% NaCl solution. The porosity rate was obtained from a comparison of the dc polarization resistance of the uncoated and coated substrates. Scratch adhesion testing was used to compare the critical loads for different coatings. XRD results showed that the sputtered films exhibit a ferritic b.c.c. $\alpha$-phase. Potentiodynamic polarization curves indicated that all samples had much higher corrosion potential and better corrosion resistance than the bare steel substrate. The corrosion performance increased with increasing power density and the adhesion was enhanced at the bias voltage of -50V. An improvement in the corrosion resistance can be obtained with a better coating adhesion. Finally, an optimized deposition condition for corrosion protection was found as $40W/cm^2$ and -50V.