• Proceedings of the Korea Information Processing Society Conference
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• 2005.05a
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• pp.1307-1310
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• 2005

$IP^2$(IP based-IMT Network Platform)은 유비쿼터스 플랫폼으로서 백본 망에서 IP 를 IPha(IP host address)와 IPra(IP routing address)으로 두 가지를 사용하여서 이동성을 지원한다. 그리고 MN(Mobile Node)도 Active 상태와 Dormant 상태로 두 가지 상태로 나뉘는데 Dormant 상태에서 상대방이 통신을 요청하면 페이징(Paging) 과정을 통해서 Active 상태로 전이된다. 페이징을 할 때 LA(Location Area)에 속해있는 모든 셀(Cell)에 페이징 메시지를 전송하게 됨으로서 네트워크의 자원을 과도하게 사용하게 된다. 이것을 해결하기 위해서 프럭시(Proxy) 를 두는 방안을 제안하였다. 프럭시에서 MN 들이 존재하는 셀 정보를 유지 함으로서 페이징 요청이 있을 때 정확한 셀에 메시지를 전송하게 되기 때문에 네트워크 자원의 낭비를 줄일 수 있다.

• Proceedings of the Korean Society for Bioinformatics Conference
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• 2006.02a
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• pp.125-126
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• 2006

NimbleGen has developed strategies to use its high-density oligonucleotide microarray platform (385,000 probes per array) to map both promoter binding sites and copy number variation at very high-resolution in the human genome. Here we describe a genome-wide map of active promoters determined by experimentally locating the sites of transcription imitation complex binding throughout the human genome using microarrays combined with chromatin immunoprecipitation. This map defines 10,567 active promoters corresponding to 6,763 known genes and at least 1,196 un-annotated transcriptional units. Microarray-based comparative genomic hybridisation (CGH) is animportant research tool for investigating chromosomal aberrations frequently associated with complex diseases such as cancer, neuropsychiatric disorders, and congenital developmental disorders. NimbleGen array CGH is an ultra-high resolution (0.5-50 Kb) oligo array platform that can be used to detect amplifications and deletions and map the associated breakpoints on the whole-genome level or with custom fine-tiling arrays. For whole-genome array CGH, probes are tiled through genic and intergenic regions with a median probe spacing of 6 Kb, which provides a comprehensive, unbiased analysis of the genome.

• Nuclear Engineering and Technology
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• v.52 no.10
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• pp.2151-2161
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• 2020

The study presents a review of research advancements in the field of gamma radiation detection systems for emergency radiation monitoring, particularly two major sub-systems namely (i) the radiation detector and (ii) the detection platform - air-borne and ground-based. The dynamics and functional characteristics of modern radiation detector active materials are summarized and discussed. The capabilities of both ground-based and aerial vehicle platforms employed in gamma radiation monitoring are deliberated in depth.

• Journal of the Korean Society of Safety
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• v.36 no.5
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• pp.36-42
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• 2021

Portable ladders are widely used as ascend and descend pathways and platforms for works at height at residential and industrial sites. In the last 10 years, 267 fatalities and 36,571 accidents related to portable ladders have been reported, suggesting a need to develop countermeasures to prevent such accidents. In this study, an in-depth focus group interview (FGI) was conducted with various stakeholders of portable ladders to survey the current usage and requirements for improving work safety. A new portable ladder called active platform ladder was developed based on the requirements suggested by the FGI. A stability test confirmed that the developed ladder is more stable than conventional ones, suggesting that it can reduce the fall accidents.

• Smart Structures and Systems
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• v.23 no.6
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• pp.695-702
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• 2019

The number of cable-stayed bridges has been increasing worldwide, causing issues in maintaining the structural safety and integrity of bridges. The stay cable, one of the most critical members in cable-stayed bridges, is vulnerable to wind-induced vibrations owing to its inherent low damping capacity. Thus, vibration mitigation of stay cables has been an important issue both in academia and practice. While a semi-active control scheme shows effective vibration reduction compared to a passive control scheme, real-world applications are quite limited because it requires complicated equipment, including for data acquisition, and power supply. This study aims to develop an Arduino-based integrated cable vibration control system implementing a semi-active control algorithm. The integrated control system is built on the low-cost, low-power Arduino platform, embedding a semi-active control algorithm. A MEMS accelerometer is installed in the platform to conduct a state feedback for the semi-active control. The Linear Quadratic Gaussian control is applied to estimate a cable state and obtain a control gain, and the clipped optimal algorithm is implemented to control the damping device. This study selects the magnetorheological damper as a semi-active damping device, controlled by the proposed control system. The developed integrated system is applied to a laboratory size cable with a series of experimental studies for identifying the effect of the system on cable vibration reduction. The semi-active control embedded in the integrated system is compared with free and passive mode cases and is shown to reduce the vibration of stay-cables effectively.

• Korean Journal of Exercise Nutrition
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• v.25 no.3
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• pp.28-35
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• 2021

[Purpose] As Panax ginseng C. A. Meyer (ginseng) exhibits various physiological activities and is associated with exercise, we investigated the potential active components of ginseng and related target genes through network pharmacological analysis. Additionally, we analyzed the association between ginseng-related genes, such as the G-protein-coupled receptors (GPCRs), and improved exercise capacity. [Methods] Active compounds in ginseng and the related target genes were searched in the Traditional Chinese Medicine Database and Analysis Platform (TCMSP). Gene ontology functional analysis was performed to identify biological processes related to the collected genes, and a compound-target network was visualized using Cytoscape 3.7.2. [Results] A total of 21 ginseng active compounds were detected, and 110 targets regulated by 17 active substances were identified. We found that the active compound protein was involved in the biological process of adrenergic receptor activity in 80%, G-protein-coupled neurotransmitter in 10%, and leucocyte adhesion to arteries in 10%. Additionally, the biological response centered on adrenergic receptor activity showed a close relationship with G protein through the beta-1 adrenergic receptor gene reactivity. [Conclusion] According to bioavailability analysis, ginseng comprises 21 active compounds. Furthermore, we investigated the ginseng-stimulated gene activation using ontology analysis. GPCR, a gene upregulated by ginseng, is positively correlated to exercise. Therefore, if a study on this factor is conducted, it will provide useful basic data for improving exercise performance and health.

• Herbal Formula Science
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• v.31 no.4
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• pp.295-313
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• 2023

Objectives : While treatments for cancer are advancing, the development of effective treatments for cancer metastasis, the main cause of cancer patient death, remains insufficient. Recent studies on Dichroae Radix have revealed that its active ingredients have the potential to inhibit cancer metastasis. This study aimed to investigate the cancer metastasis inhibitory effect of Dichroae Radix using network pharmacological analysis. Methods : The active compounds of Dichroae Radix have been identified using Traditional Chinese Medicine System Pharmacology Database and Analysis Platform. The UniProt database was used to collect each of information of all target proteins associated with the active compounds. To find the bio-metabolic processes associated with each target, the DAVID6.8 Gene Functional classifier tool was used. Compound-Target and Target-Pathway networks were analyzed via Cytoscape 3.40. Results : In total, 25 active compounds and their 62 non-redundant targets were selected through the TCMSP database and analysis platform. The target genes underwent gene ontology and pathway enrichment analysis. The gene list applied to the gene ontology analysis revealed associations with various biological processes, including signal transduction, chemical synaptic transmission, G-protein-coupled receptor signaling pathways, response to xenobiotic stimulus, and response to drugs, among others. A total of eleven genes, including HSP90AB1, CALM1, F2, AR, PAKACA, PTGS2, NOS2, RXRA, ESR1, ESR2, and NCOA1, were found to be associated with biological pathways related to cancer metastasis. Furthermore, nineteen of the active compounds from Dichroae Radix were confirmed to interact with these genes. Conclusions : The results provide valuable insights into the mechanism of action and molecular targets of Dichroae Radix. Notably, Berberine, the main active ingredient of Dichroae Radix, plays a significant role in degrading AR proteins in advanced prostate cancer. Further studies and validations can provide crucial data to advance cancer metastasis prevention and treatment strategies.

• Journal of Digital Contents Society
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• v.18 no.7
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• pp.1267-1280
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• 2017

This study examines the changes of the online music market and revenue models by the theory of network society and communications of Manuel Castells for the content platform. As a result of this study, we found that active communications among the members in the network, played a crucial role in the creation of contents and the promotions of profit for platform providers. It is especially important to create an environment in which members can voluntarily communicate rather than an artificial control. The content platform business consists of people, thus it has been proven that providing play elements of culture and society are important, as well as necessary conditions to the generation related to content based platform businesses.

• Journal of the Korea Society of Computer and Information
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• v.21 no.7
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• pp.31-38
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• 2016

In this paper, we propose a direction for improving 'Geospatial information open platform' service to support the converged and integrated geospatial information. Since there can be a number of issues relating to the support for geospatial information convergence industry, two qualitative surveys were performed to collect opinions comprehensively and specifically. The responses from 165 experts from 5 areas that use geospatial information were used, and the requirements of demanders were divided into the aspect of policy, aspect of data development and distribution, and aspect of data utilization support in order to effectively analyze the survey results. As a result, a total of 26 major issues were derived and it was deemed that it is necessary to find a way to expand the role of 'Geospatial information open platform' from "Open-API Oriented Passive Spatial Information Open Platform" to "Platform that Comprehensively Provides Active Convergence Support Information" order to resolve the issues derived.

• The Journal of Asian Finance, Economics and Business
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• v.8 no.10
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• pp.317-326
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• 2021

The crowdsourcing system relies heavily on the number of crowd participation on the platform to ensure the platform's success. However, exploring factors that motivate the crowds to sustain on the platform remains unclear, and very little literature was found on this matter. Lately, the COVID-19 pandemic has affected the world, including Malaysia. Due to the pandemic, many people have lost their jobs, and hence, most of them have shifted to digital work. Hence, to understand the motivation for continuous participation on the online crowdsourcing platform among low-income crowd workers (B40) in Malaysia, this paper explores the intrinsic and extrinsic motivations for continuous participation. A qualitative method interview was performed where 14 active participants of Upwork.com, under the GLOW program, took part during the data collection process. This paper used the thematic analysis method to extract the data collected from this study. The finding of this study identified eight intrinsic motivation factors: (1) personal development, (2) pastime, (3) fun, (4) passion, (5) task identity, (6) time-workplace flexibility, (7) altruistic, and (8) peers' success and four extrinsic factors: (1) monetary, (2) job security, (3) personal commitment, and (4) environment.