• 정보학연구
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• 제7권1호
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• pp.87-104
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• 2004

정보통신기술의 발달로 인한 물류활동의 발달로 인하여 물류서비스를 통한 경쟁우위라는 점이 부각되면서 물류기능이 단순한 지원기능이 아니라 고객유지를 위한 전략적인 경쟁우위의 중요한 원천으로 인식되고 있다. 특히 기업경영의 세계화에 따라 물류정보의 첨단화가 요구됨으로써 사이버물루(e-logistics)환경이 전략적 물류관리의 성패요인으로 작용하면서 정보화시대의 e-물류효율화의 중용성이 대두되고 있다. 본 연구는 정보화시대의 e-물류변화와 국제물류의 주축을 이루고 있는 제3자 물류와 제4자 물류의 기능을 비교하고 국제 e-물류를 활성화시키기 위해서 종합물류정보망 구축, 법률과 제도개선, 정보표준화의 추진, 기업의 효율적인 물류전략 추진, 물류업체간 전략적 제휴, e-물류환경의 기반구축 등의 문제들을 중심으로 전략적 물류관리방안들을 제시하였다.

• 한국비블리아학회지
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• 제32권1호
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• pp.315-334
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• 2021

본 연구는 용산구 공공도서관의 발전계획 수립을 위한 기초연구로써, 용산구 도서관의 운영 효율화를 위한 활성화 방안을 제시하는 데 목적이 있다. 이를 위해 공공도서관 운영 현황 및 활성화 방안 관련 선행연구를 조사하여 현황 분석을 위해 고려되어야 할 지역 특성, 도서관 시설, 인력, 장서 및 예산, 프로그램 등의 기본 요인을 도출하였다. 이러한 요인을 기반으로 용산구 지역 여건 및 공공도서관 운영 현황을 분석하였으며, 사서 및 전문가 인터뷰를 통해 용산구 도서관의 문제점 및 운영 개선 방안을 모색하였다. 이를 바탕으로 대표도서관 건립 및 도서관 수 확충, 독서문화확산 및 지역특화프로그램 개발, 인력 및 장서 확충, 지역사회 유기적 협력체계 구축 등의 활성화 방안을 제시하였다.

• 디지털융복합연구
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• 제19권9호
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• pp.299-305
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• 2021

본 연구는 비대면 시대의 온·오프라인 통합매장의 서비스 활성화를 위한 사례 연구이다. COVID-19로 인해 리테일 아포칼립스 위기가 심화되었고, 이를 극복하기 위해 오프라인 매장에 온라인 경험을 제공하는 피지털 전략이 주목을 받고 있다. 하지만 국내 유통업체의 대응은 초기단계이며 소비자의 접근성을 향상시키고 오프라인 매장을 활성화하기 위한 전략적 연구가 필요한 실정이다. 기술 발전에 따른 이론적 고찰을 통해 3가지 전략을 확인하였고, 국내외 선행 사례를 조사, 분석하여 4가지 전략으로 정리하였다. 도출된 전략을 유형화하여 결론적으로 3가지 핵심 전략을 제시하였다. 이 연구는 문헌 조사와 사례조사를 토대로 한 연구로서 향후 온·오프라인 통합매장을 활성화하기 위한 전략적 기초자료를 구축하는 데 도움이 될 것으로 기대한다.

• Natural Product Sciences
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• 제16권4호
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• pp.280-284
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• 2010

During liver fibrosis, hepatic stellate cells (HSCs) undergo a complex activation process characterized by increased proliferation and extracellular matrix deposition, which is the major pathological feature of hepatic cirrhosis. Therefore, suppression of HSCs activation has been proposed as therapeutic strategies for hepatic fibrosis. We tried to screen the antifibrotic activity of natural products employing HSC-T6, hepatic stellate cell lines as an in vitro assay system. In the present study, we investigated the antiproliferative activity of aerial parts and roots of Pulsatilla koreana Nakai (Ranunculaceae). Our present study shows that roots of P. koreana exerted more strong inhibitory activity compared to its aerial parts. In addition, among the fractions of the aqueous methanolic extract of P. koreana roots, both n-hexane and $CHCl_3$ fraction showed the strong inhibitory activity on HSC proliferation. Further study also demonstrated that the n-hexane and $CHCl_3$ fraction of P. koreana roots significantly inhibited the HSC proliferation in time- and concentration-related manners.

• 대한공간정보학회지
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• 제20권2호
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• pp.39-46
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• 2012

최근에 공간정보의 활용 분야가 도시계획, 시설물 관리, 교통서비스 등의 활용 서비스에서 환경오염, 자원확보, u-City 등의 새로운 분야로 확대되고 있다. 특히, 스마트폰을 기반으로 한 모바일 환경에서의 공간정보 활용의 중요성이 높아짐에 따라 모바일 공간정보 서비스를 제공하기 위한 모바일 공간정보기반 구축 및 관련 정책 개발의 필요성도 증대되고 있다. 따라서 본 연구에서는 차세대 전략산업으로 육성할 필요성이 있는 모바일 공간정보분야에 대한 현황조사를 통해 문제점을 분석하고, 이에 대한 활성화 방안으로서 공공부문의 역할과, 모바일 공간정보 서비스 개발, 모바일 공간정보기반 구축방안 및 활성화를 위한 단계적 추진전략을 제시하였다.

• 한국농촌건축학회논문집
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• 제18권2호
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• pp.39-46
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• 2016

The purpose of this study was to analyze the preferences for the physical features of return farmer housing. Housing problems of rural areas is one of the important factors that determine the quality of life in rural areas. Through these return farmer housing as it wants to improve the living environment of rural areas. The purpose of this study aims to find the required characteristics of the return farmer for rural activation. The survey was conducted to target the return farmer households living in housing and expectant return farmer living in the rural. The results of this study were as follows. First, expectant return farmer than return farmer are more importance to house outside(environmental) factors. Showed that environmental conditions are more important than housing conditions, expectant return farmer of residential satisfaction. Second, return farmer prefer ratio was higher House prices and sizes, expectant return farmer among the external factors such as environmental conditions is the distance to the workplace were very important. The results of this study can be a basis for effective strategies for future rural activation. More sustainable in the future, including the analysis of various parameters in progress by being linked to policy measures that will be provided. This study aims to be the foundation of sustainable housing policies for return farmer households.

• PNF and Movement
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• 제2권1호
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• pp.25-33
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• 2004

Purpose : The purpose of this article is to summarize the characteristics of isotonic combination. Method : Some studies of the motor unit activation patterns during isometric, concentric, and eccentric actions, neural strategies in the control of muscle force, and concentric versus combined concentric-eccentric training were reviewed. Results & Conclusions : Eccentric torque may be relatively higher than concentric torque for two potential reasons: 1) stretch responses in the antagonist are not elicited to restrain the motion as can occur concentrically and 2) stretch responses in the agonist may augment eccentric torque production. Concentric-eccentric training has a greater influence on functional capacity than that of concentric training. Both maximal force and average force throughout the motion were significantly higher when the dynamic action was started with preactivation as compared to the mode without preactivation. The peak torques observed during the concentric phase of the eccentric-concentric muscle actions were higher than those noted in the pure concentric contraction.

• 농촌계획
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• 제26권2호
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• pp.83-93
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• 2020

Rural areas have been faced with various problems such as aging and population decline, and in these circumstances, the activation of local communities is suggested as a solution. Agricultural producer organizations are a powerful means of maintaining rural society. The purpose of this study is to understand the characteristics of agricultural community activities by region by comparing the status of organization and activities and analyzing Location Quotient(LQ) based on the regional survey data in the 2015 census of agriculture, forestry, and fisheries. As the results of the analysis, it was found that 38.35% of villages participated in economic organizations and 32.22% of villages were having urban-rural exchange activities. The crop clubs were actively operated in the Gyeongsangbuk province, and other economic organizations were organized in Jeju, Haenam-gun, and Dangjin-si more than other regions. And the urban-rural exchange activities were found in Chungcheongnam province mainly. The results of detailed LQ analysis by organization and activity showed that specialized regions for each community or activity were different. These results could be used for regional planning or the establishment of strategies for community activation.

• The Plant Pathology Journal
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• 제37권5호
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• pp.415-427
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• 2021

A plethora of compounds stimulate protective mechanisms in plants against microbial pathogens and abiotic stresses. Some defense activators are synthetic compounds and trigger responses only in certain protective pathways, such as activation of defenses under regulation by the plant regulator, salicylic acid (SA). This review discusses the potential of naturally occurring plant metabolites as primers for defense responses in the plant. The production of the metabolites, hexanoic acid and melatonin, in plants means they are consumed when plants are eaten as foods. Both metabolites prime stronger and more rapid activation of plant defense upon subsequent stress. Because these metabolites trigger protective measures in the plant they can be considered as "vaccines" to promote plant vigor. Hexanoic acid and melatonin instigate systemic changes in plant metabolism associated with both of the major defense pathways, those regulated by SA- and jasmonic acid (JA). These two pathways are well studied because of their induction by different microbial triggers: necrosis-causing microbial pathogens induce the SA pathway whereas colonization by beneficial microbes stimulates the JA pathway. The plant's responses to the two metabolites, however, are not identical with a major difference being a characterized growth response with melatonin but not hexanoic acid. As primers for plant defense, hexanoic acid and melatonin have the potential to be successfully integrated into vaccination-like strategies to protect plants against diseases and abiotic stresses that do not involve man-made chemicals.

• 한양메디칼리뷰
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• 제33권1호
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• pp.59-64
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• 2013

Cancer remains the leading cause of death worldwide despite intense efforts in developing innovative treatments. Current approaches in cancer therapy are mainly directed to a selective targeting of cancer cells to avoid potential side effects associated with conventional therapy. In this respect, Natural killer (NK) cells have gained growing attention and are now being considered as promising therapeutic tools for cancer therapy owing to their intrinsic ability to rapidly recognize and kill cancer cells, while sparing normal healthy cells. NK cells play a key role in the first line of defense against transformed and virus-infected cells. NK cells sense their target through a whole array of receptors, both activating and inhibitory. Functional outcome of NK cell against target cells is determined by the balance of signals transmitted from diverse activating and inhibiting receptors. Despite significant progress made in the role of NK cells attack as a pivotal sentinel in tumor surveillance, the molecular has been that regulate NK cell responses remain unclear, which restricts the use of NK cells as a therapeutic measure. Accordingly, current efforts for NK cell-based cancer therapy have largely relied on the strategies that are based on the manipulation of inhibitory receptor function. However, if we better understand the mechanisms governing NK cell activation, including those mediated by diverse activating receptors, this knowledge can be applied to the development of optimal design for cancer immunotherapy by targeting NK cells.