• Bulletin of the Korean Chemical Society
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• v.21 no.5
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• pp.487-492
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• 2000

The combustion characteristics of a mixture of acetaldehyde, oxygen and argon behind a reflected shock wave at temperatures ranging from 1320 to 1897 K at 100 torr were studied. The emission from the OH radical at 306.4 nm and the pressure profile behind the reflected shock were measured to monitor ignition delay time. The ignition delay times were computed from a proposed mechanism of 110 elementary reactions involving 34 species. The simulation and sensitivity analysis confirm that the main channel for oxidation of acetaldehyde at high temperature consists of the Rice-herzfeld mechanism, the decomposition and oxidation of HCO, and the reaction of H with $O_2$.

• Korean Journal of Food Science and Technology
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• v.9 no.2
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• pp.116-122
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• 1977

The volatile flavor components of Kimchis were identified and the volatiles of fermented Kimchis (1.29% NaCl and 4.89 NaCl) were compared with those of raw Kimchi (1.29% NaCl). After the existence of carbonyls and sulfur compounds were confirmed by precipitation method, vacuum distillation was carried out to collect the volatiles of Kimchis in traps submerged in ice+salt, dryice-acetone and liquid N, respectively. The volatile flavor components were identified by GLC. The results were; 1. 17 volatile flavor components of Kimchis were identified by comparison of retention time with those of known compounds and acetaldehyde, acetone, ethanol, ethyl sulfide were positively identified by m.p., IR, UV, TLC. etc. 2. Ethanol was the most abundant volatiles of Kimchis and the content was much higher in fermented low salt Kimchi than in unfermented low salt Kimchi. 3. On the contrary, acetaldehyde and volatile sulfur compounds were reduced in fermented Kimchis, especially in fermented low salt Kimchi.

• Journal of Physiology & Pathology in Korean Medicine
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• v.21 no.2
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• pp.387-391
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• 2007

Recently, much attention has been paid to developing various kinds of fermented herbal extracts, a new type of traditional herbal medicine, in the field of Korean traditional medicine. The fermentation of medicinal herbs is intended to exert a favorable influence on digestability, bioavailavility and pharmacological activity of herbal extract in the gastrointestinal tract. It also produces a number of fermentation products that intensify the nutritional and pharmacological aspects of the medicinal herbs. In order to develop a functional beverage of alleviating the aftereffects of the previous drinks, the extracts (HP-1) of fermented herbal mixture, including Artemisia capillaris Thunb., Lonicera japonica Thunberg, and Hovenia dulcis Thunb., were prepared and the medicinal effect as a hangover cure was evaluated in ethanol-loaded rats. The enzyme activities of alcohol dehydrogenase (ADH) and acetaldehyde dehydrogenase-2 (ALDH2) were analyzed by measuring the concentration of blood ethanol and acetaldehyde. The mRNA expression of ADH and ALDH2 was also investigated through RT-PCR analysis. In the HP-1-treated group, the concentration of blood ethanol was significantly reduced at one hour after loading of ethanol, as compared to that in the saline-treated group. The reduced ethanol was converted to acetaldehyde, which resulted in rapid increase in acetaldehyde concentration in an hour. Acetaldehyde was started to decrease at 5 hours after ethanol loading. It implies that HP-1 is highly effective to stimulate the activities of ADH and ALDH2. The HP-1 treatment also activated the mRNA expression of ADH and ALDH. This study suggests that fermented herbal extract, HP-1 can be used as a functional beverage of alleviating the alcohol-induced hangover symptoms by stimulating the activities and gene expression of hepatic alcohol metabolizing enzymes.

• Journal of Life Science
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• v.32 no.2
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• pp.79-85
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• 2022

Recently, many hangover cure products containing natural ingredients have been made available in the market that are effective for alcohol-related liver damage or for improved liver function. However, the cure for of liver damage or medication for improved liver function are different from hangover cure. Therefore, the efficacy hangover cure products needs to be verified. In this study, we investigated and compared the ameliorating effect of four commercially available hangover cure products on acute ethanol-induced hangover in Sprague - Dawley rats. The four samples were labeled as C, M, R, and S. The efficacy of the samples was evaluated based on the serum concentration and area under the curve (AUC) of blood ethanol and acetaldehyde concentrations to quantitatively assess the hangover cure effect. Ethanol administration to the rats significantly raised the serum alcohol and acetaldehyde levels. The Cmax reduction rates of ethanol for the samples C, M, R, and S were 5.9%, 3.1%, 8.4%, and 11.7%, and the AUC were 8.9%, 2.2%, 12.1%, and 19.6%, respectively, whereas the Cmax reduction rates of acetaldehyde were 14.2%, 15.2%, 28.2%, and 35.0%, and the AUC were 21.6%, 7.5%, 22.4%, and 29.9%, respectively. In conclusion, all samples showed a tendency to relieve hangover in the order of S, R, C, and M in terms of the ethanol concentration, but only sample S showed a statistically significant decrease in both Cmax and AUC for ethanol and acetaldehyde. These results suggest that an objective method for verifying the efficacy of hangover cure products is lacking.

• Korean Chemical Engineering Research
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• v.61 no.3
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• pp.472-478
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• 2023

In this study, the acetaldehyde removal characteristics of activated carbon (AC) for air purifier filters were investigated using metal catalysts-impregnation and functional group-modification method. The AC with a high specific surface area(1700 m²/g) and micropores was prepared by KOH activation of coconut charcoal and the efficiency of catalyst and functional group immobilization was examined by varying the drying conditions within the pores after immersion. The physical properties of the prepared activated carbon were analyzed by BET, ICP, EA, and FT-IR, and the acetaldehyde adsorption performances were investigated using gas chromatography (GC) at various impregnation and modified conditions. As the concentration of impregnation solution increased, the amount of impregnated metal catalysts increased, while the specific surface area showed a decreasing trend. The adsorption tests of the metal catalyst-impregnated and functional group-modified activated carbons revealed that excellent adsorption performance in compositions MgO10@AC, CaO10@AC, EU10@AC, and H-U3N1@AC, respectively. The MgO10@AC, which showed the highest adsorption performance, had a breakthrough time of 533.8 minutes and adsorption capacity of 57.4 mg/g for acetaldehyde adsorption. It was found that the nano-sized MgO catalyst on the activated carbon improved the adsorption performance by interacting with carbonyl groups of acetaldehyde.

• Proceedings of the Korea Air Pollution Research Association Conference
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• 2001.11a
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• pp.427-428
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• 2001

여수지역은 배후에 여수산단이라는 대규모 석유화학공단이 위치하고 있으며, 대기보전 특별대책지역 (환경부고시 제96-116호)으로 지정되어 있다. 광양만을 중심으로 여수, 광양, 순천지역은 대기환경 규제지역(환경부고시 제99-191호)으로 지정되어 중점 관리되고 있는 지역이다. 특히 acetaldehye 및 methanol은 $O_3$의 전구물질로 배출이 제한되지만 석유화학공단 등에서 반응에 필요한 기초 반응물질로 사용되고 있다. (중략)

• Proceedings of the Korea Air Pollution Research Association Conference
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• 2002.11a
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• pp.348-349
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• 2002

시화·반월 공단은 4000여 중소기업이 밀집되어 있어 대기오염 물질 배출이 다른 지역보다 맡고 이중 다량의 악취 배출업소가 거주지역과 인접되어 있어 주민 생활환경에 심각한 영향을 미치고 있다. 또한 업종의 다양성으로 악취 문제의 원인 파악조차 힘든 지역으로 악취와 관련된 민원이 끊이지 않고 있어 악취에 대한 심각한 경각심을 불러일으키고 있다(김덕현, 시흥환경기술개발센터, 2001). (중략)

• Journal of Microbiology
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• v.37 no.1
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• pp.41-44
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• 1999

Human mitochondrial aldehyde dehydrogenase 2 (ALDH2) is mainly responsible for oxidation of acetaldehyde generated during alcohol oxidation in vivo. A full-length cDNA of human liver ALDH2 was successfully expressed using a vaccinia virus-T7 RNA polymerase system. The expressed ALDH2 had an enzymatic activity as high as the native human liver ALDH2 enzyme.

• Proceedings of the PSK Conference
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• 2003.10b
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• pp.160.3-161
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• 2003

Aldehyde and active form of free oxygen produced in alcohol metabolism in liver are the cause of liver cell damage. The main system of alcohol metabolism is composed of alcohol dehydrogenase(ADH), aldehyde dehydrogenase(ALDH) and cytochrome P4502E1. Alcohol dehydrogenase is reversible in alcohol metabolism. To block the backward reaction and enhance alcohol oxidation, acetaldehyde trapping agents were assayed. The assay was carried out by measuring decreasing NADH at 340nm, using acetaldcehyde and NADH as substrate and coenzyme respectively. (omitted)

• Proceedings of the Korean Institute of Building Construction Conference
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• 2022.11a
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• pp.181-182
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• 2022

The properties of cement mortar with nano-heterojunction photocatalysts were investigated in this study. The following tests were conducted with the cement mortar : (1) Flow test of fresh cement mortar, (2) compressive strength and (3) acetaldehyde removal efficiency under visible light. Results indicated that the cement mortar with nano-heterojunction photocatalysts showed higher compressive strength and higher acetaldehyde removal efficiency as the mixing ratio of nano-heterojunction increased.