• Investigative Magnetic Resonance Imaging
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• 제21권2호
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• pp.71-81
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• 2017

Purpose: To compare three, motion-resistant, T1-weighted MR sequences on the hepatobiliary phase for gadoxetic acid-enhanced MR imaging of the liver. Materials and Methods: In this retrospective study, 79 patients underwent gadoxetic acid-enhanced, 3T liver MR imaging. Fifty-nine were examined using a standard protocol, and 20 were examined using a motion-resistant protocol. During the hepatocyte-specific phase, three MR sequences were acquired: 1) gradient recalled echo (GRE) with controlled aliasing in parallel imaging results in higher acceleration (CAIPIRINHA); 2) radial GRE with the interleaved angle-bisection scheme (ILAB); and 3) radial GRE with golden-angle scheme (GA). Two readers independently assessed images with motion artifacts, streaking artifacts, liver-edge sharpness, hepatic vessel clarity, lesion conspicuity, and overall image quality, using a 5-point scale. The images were assessed by measurement of liver signal-to-noise ratio (SNR), and tumor-to-liver contrast-to-noise ratio (CNR). The results were compared, using repeated post-hoc, paired t-tests with Bonferroni correction and the Wilcoxon signed rank test with Bonferroni correction. Results: In the qualitative analysis of cooperative patients, the results for CAIPIRINHA had significantly higher ratings for streak artifacts, liver-edge sharpness, hepatic vessel clarity, and overall image quality as compared to, radial GRE, (P < 0.016). In the imaging of uncooperative patients, higher scores were recorded for ILAB and GA with respect to all of the qualitative assessments, except for streak artifact, compared with CAIPIRINHA (P < 0.016). However, no significant differences were found between ILAB and GA. For quantitative analysis in uncooperative patients, the mean liver SNR and lesion-to-liver CNR with radial GRE were significantly higher than those of CAIPIRINHA (P < 0.016). Conclusion: In uncooperative patients, the use of the radial GRE sequence can improve the image quality compared to GRE imaging with CAIPIRINHA, despite the data acquisition methods used. The GRE imaging with CAIPIRINHA is applicable for patients without breath-holding difficulties.

• KSII Transactions on Internet and Information Systems (TIIS)
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• 제11권3호
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• pp.1684-1699
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• 2017

The deblocking filter (DF) reduces blocking artifacts in encoded video sequences, and thereby significantly improves the subjective and objective quality of videos. Statistics show that the DF accounts for 5-18% of the total decoding time in high-efficiency video coding. Therefore, speeding up the DF will improve codec performance, especially for the decoder. In view of the rapid development of multicore technology, we propose a parallel DF scheme based on a modified order of accessing the coding tree units (CTUs) by analyzing the data dependencies between adjacent CTUs. This enables the DF to run in parallel, providing accelerated performance and more flexibility in the degree of parallelism, as well as finer parallel granularity. We additionally solve the problems of variable privatization and thread synchronization in the parallelization of the DF. Finally, the DF module is parallelized based on the HM16.1 reference software using OpenMP technology. The acceleration performance is experimentally tested under various numbers of cores, and the results show that the proposed scheme is very effective at speeding up the DF.

• Earthquakes and Structures
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• 제14권2호
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• pp.129-142
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• 2018

The current paper introduces a new approach for development of damage index to obtain the maximum damage in the reinforced concrete frames caused by as-recorded single and consecutive earthquakes. To do so, two sets of strong ground motions are selected based on maximum and approximately maximum peak ground acceleration (PGA) from "PEER" and "USGS" centers. Consecutive earthquakes in the first and second groups, not only occurred in similar directions and same stations, but also their real time gaps between successive shocks are less than 10 minutes and 10 days, respectively. In the following, a suite of six concrete moment resisting frames, including 3, 5, 7, 10, 12 and 15 stories, are designed in OpenSees software and analyzed for more than 850 times under two groups of as-recorded strong ground motion records with/without seismic sequences phenomena. The idealized multilayer artificial neural networks, with the least value of Mean Square Error (MSE) and maximum value of regression (R) between outputs and targets were then employed to generate the empirical charts and several correction equations for design utilization. To investigate the effectiveness of the proposed damage index, calibration of the new approach to existing real data (the result of Park-Ang damage index 1985), were conducted. The obtained results show good precision of the developed ANNs-based model in predicting the maximum damage of regular reinforced concrete frames.

• Fisheries and Aquatic Sciences
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• 제9권4호
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• pp.167-174
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• 2006

Two typical responses have been documented for flatfish when they encounter the ground gear of bottom trawls: herding response and falling back response. These two responses were analyzed from video recordings of fish and were characterized by time sequences for four parameters: swimming speed, angular velocity, acceleration, and distance between the fish and the ground gear. When flatfish displayed the falling-back response, absolute values of the three swimming parameters and their deviations were significantly higher than those during the herding response. However, the swimming parameters were not dependent on the distance between the flatfish and the ground gear, regardless of which response occurred. The dominant periods for most of the movement parameters ranged from 2.0 to 3.7 s, except that no periodicity was observed for swimming speed or angular velocity during the falling-back response. However, variations in the four parameters during the falling -back response revealed greater irregularity in periodicity and higher amplitudes. This complex behavior is best described as a chaos phenomenon' and is discussed as the building block for a model predicting the responses of flatfish to ground gear as part of the general understanding of the fish capture process.

• 천문학회보
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• 제44권1호
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• pp.82.2-82.3
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• 2019

Korea Astronomy and Space Science Institute (KASI), in collaboration with the NASA Goddard Sparce Flight Center (GSFC), will develop a next generation coronagraph for the International Space Station (ISS). COronal Diagnostic EXperiment (CODEX) uses multiple filters to obtain simultaneous measurements of electron density, temperature, and velocity within a single instrument. CODEX's regular, systematic, comprehensive dataset will test theories of solar wind acceleration and source, as well as serve to validate and enable improvement of space-weather/operational models in the crucial source region of the solar wind. CODEX subsystems include the coronagraph, pointing system, command and data handling (C&DH) electronics, and power distribution unit. CODEX is integrated onto a standard interface which provides power and communication. All full resolution images are telemeters to the ground, where data from multiple images and sequences are co-added, spatially binned, and ratioed as needed for analysis.

• 한국항행학회논문지
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• 제27권3호
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• pp.306-313
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• 2023

실사 및 그래픽 기반 가상현실 콘텐츠는 360도 영상을 기반으로 하며, 시청자의 의도나 자동 추천 기능을 통한 뷰포트 추출이 필수적이다. 본 논문은 360도 영상에서 다중 객체 추적 기반의 뷰포트 추출 시스템을 설계하고, 다중 뷰포트 추출에 필요한 병렬화된 연산 구조를 제안한다. 360도 영상에서 뷰포트 추출 과정을 ERP 좌표의 3D 구 표면 좌표 변환과 3D 구 표면 좌표의 뷰포트 내 2D 좌표 변환 과정을 순서대로 픽셀 단위의 스레드로 구성하여 연산을 병렬화하였다. 제안 구조는 항공 360도 영상 시퀀스들에 대하여 최대 30개의 뷰포트 추출 과정에 대한 연산 시간이 평가되었으며, 뷰포트 수에 정비례하는 CPU 기반 연산 시간에 비해 최대 5240배 가속화됨을 확인하였다. ERP 프레임 I/O 시간을 줄일 수 있는 고속의 I/O나 메모리 버퍼를 사용 시 뷰포트 추출 시간을 7.82배 추가 가속화가 가능하다. 제안하는 뷰포트 추출 병렬화 구조는 360도 비디오나 가상현실 콘텐츠들에 대한 동시 다중 접속 서비스나 사용자별 영상 요약 서비스 등에 활용될 수 있다.

• Journal of Advanced Marine Engineering and Technology
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• 제36권4호
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• pp.490-496
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• 2012

본 연구의 목적은 바지선에 의해 발생하는 해상풍력발전기의 충격손상을 최소화 시키기 위한 것이다. 충격해석은 상용유한요소해석 프로그램인 ANSYS LS-Dyna를 통하여 분석하였다. 바지선속을 변화시켜 다양한 상태의 하중케이스를 고려하였고 충격방지고무의 비선형성을 고려한 시간이력해석을 수행하였으며 변형률 에너지, 전체 변형량, 플라스틱 변형률, 내부충격에너지, 영구손상된 변형량 등을 검토하였다. 충격속도에 변화에 따른 영구변형을 확인한 후 자연고무, 복합고무, 네오프렌 등의 고무시험 물성치로부터 구한 Mooney-Rivlin 상수를 적용하여 적절한 충격방지고무의 두께를 제안하였다. 본 연구를 통하여 구조물의 두께와 충격방지고무의 두께비에 대한 경향을 파악할 수 있으며 구조물의 설계에 적용할 수 있다.

• Nuclear Engineering and Technology
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• 제47권1호
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• pp.26-32
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• 2015

During the course of a severe accident in a light water nuclear reactor, large amounts of hydrogen can be generated and released into the containment during reactor core degradation. Additional burnable gases [hydrogen ($H_2$) and carbon monoxide (CO)] may be released into the containment in the corium/concrete interaction. This could subsequently raise a combustion hazard. As the Fukushima accidents revealed, hydrogen combustion can cause high pressure spikes that could challenge the reactor buildings and lead to failure of the surrounding buildings. To prevent the gas explosion hazard, most mitigation strategies adopted by European countries are based on the implementation of passive autocatalytic recombiners (PARs). Studies of representative accident sequences indicate that, despite the installation of PARs, it is difficult to prevent at all times and locations, the formation of a combustible mixture that potentially leads to local flame acceleration. Complementary research and development (R&D) projects were recently launched to understand better the phenomena associated with the combustion hazard and to address the issues highlighted after the Fukushima Daiichi events such as explosion hazard in the venting system and the potential flammable mixture migration into spaces beyond the primary containment. The expected results will be used to improve the modeling tools and methodology for hydrogen risk assessment and severe accident management guidelines. The present paper aims to present the methodology adopted by Institut de Radioprotection et de $S{\hat{u}}ret{\acute{e}}$ $Nucl{\acute{e}}aire$ to assess hydrogen risk in nuclear power plants, in particular French nuclear power plants, the open issues, and the ongoing R&D programs related to hydrogen distribution, mitigation, and combustion.

• 한국소음진동공학회:학술대회논문집
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• 한국소음진동공학회 2009년도 춘계학술대회 논문집
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• pp.108-108
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• 2009

본 연구의 목적은 바지선에 의해 발생하는 해상풍속측정용 마스트 구조물의 충격손상을 최소화 시키기 위한 것이다. 마스트와 바지선 사이의 충격은 보통 복잡한 형태로 이루어진다. 충격해석은 상용유한요소해석 프로그램인 ANSYS LS-Dyna를 통하여 분석하였다. 바지선속을 변화시켜 다양한 상태의 하중케이스를 고려하였고 충격방지고무의 비선형성을 고려한 시간이력해석을 수행하였으며 변형률 에너지, 전체 변형량, 플라스틱 변형률, 내부충격에너지, 영구손상된 변형량 등을 검토하였다. 해상상태조건인 해양파의 운동과 바지선의 상하방향 운동을 무시하는 것으로 가정하였다. 충격속도에 변화에 따른 영구변형을 확인한 후 자연고무, 복합고무, 네오프렌 등의 고무시험 물성치로부터 구한 Mooney-Rivlin 상수를 적용하여 적절한 충격방지고무의 두께를 제안하였다. 본 연구를 통하여 구조물의 두께와 충격방지고무의 두께비에 대한 경향을 파악할 수 있으며 구조물의 설계에 적용할 수 있게 된다. 추후 해상조건을 고려한 연구를 수행해야 할 것이다.

• Journal of Genetic Medicine
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• 제6권1호
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• pp.1-7
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• 2009

프로모터 CpG island 과메틸화와 히스톤 변경으로 대변되는 후성유전적 변화는 거의 모든 종류의 암에서 발견되는 중요한 발암기전이다. 인간유전자의 60-70% 가량이 프로모터에 CpG islands를 가지고 있으며, 이 유전자들 중 일부가 과메틸화됨으로써 해당유전자의 발현이 차단되고, 종양억제기능이 소실되어 종양세포의 성장을 촉진하게 된다. 암에는 프로모터 CpG island 과메틸화라는 국소적 변화 이외에, 유전체 전반에 걸친 탈메틸화를 동시에 보이는 경우가 대부분인데, 이러한 유전체 저메틸화는 염색체 불안정성과 밀접한 연관관계가 있다. 국소적 과메틸화와 전반적인 저메틸화라는 이러한 상반된 DNA 메틸화 변화는 암세포뿐만 아니라 그 전단계 병변인 이 형성 병변에서도 관찰된다. 프로모터CpG island 과메틸화는 유전자 발현억제 기전으로서의 중요성뿐만 아니라 종양표지자로서의 중요성이 부각되고 있다. 즉, 정상세포에서는 관찰되지 않으면서 암세포에서만 관찰되는 프로모터 CpG island 과메틸화는 암세포의 바이오마커로서의 가치가 있으며, 이를 이용하여 체액에서 암을 진단하려는 시도들이 이루어지고, 이를 활용한 암의 분자진단방법이 개발되고 있다. 또한 이러한 DNA 메틸화는 암환자의 예후 판정이나 항암치료제의 감수성 결정 등에 활용되고 있다. 본 원고에서는 인체 암세포에서의 DNA 메틸화 변화에 관하여 소개하고자 한다.