• Earthquakes and Structures
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• 제3권5호
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• pp.629-647
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• 2012

Multiple acceleration sequences of earthquake ground motions have been observed in many regions of the world. Such ground motions can cause large damage to the structures due to accumulation of inelastic deformation from the repeated sequences. The dynamic analysis of inelastic structures under repeated acceleration sequences generated from simulated and recorded accelerograms without sequences has been recently studied. However, the characteristics of recorded earthquake ground motions of multiple sequences have not been studied yet. This paper investigates the gross characteristics of earthquake records of multiple sequences from an engineering perspective. The definition of the effective number of acceleration sequences of the ground shaking is introduced. The implication of the acceleration sequences on the structural response and damage of inelastic structures is also studied. A set of sixty accelerograms is used to demonstrate the general properties of repeated acceleration sequences and to investigate the associated structural inelastic response.

• Korean Journal of Radiology
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• 제21권1호
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• pp.77-87
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• 2020

Objective: To assess the feasibility of simultaneous multislice-accelerated diffusion-weighted imaging (SMS-DWI) of the rectum in comparison with conventional DWI (C-DWI) in rectal cancer patients. Materials and Methods: This study included 65 patients with initially-diagnosed rectal cancer. All patients underwent C-DWI and SMS-DWI with acceleration factors of 2 and 3 (SMS2-DWI and SMS3-DWI, respectively) using a 3T scanner. Acquisition times of the three DWI sequences were measured. Image quality in the three DWI sequences was reviewed by two independent radiologists using a 4-point Likert scale and subsequently compared using the Friedman test. Apparent diffusion coefficient (ADC) values for rectal cancer and the normal rectal wall were compared among the three sequences using repeated measures analysis of variance. Results: Acquisition times using C-DWI, SMS2-DWI, and SMS3-DWI were 173 seconds, 107 seconds, (38.2% shorter than C-DWI), and 77 seconds (55.5% shorter than C-DWI), respectively. For all image quality parameters other than distortion (margin sharpness, artifact, lesion conspicuity, and overall image quality), C-DWI and SMS2-DWI yielded better results than did SMS3-DWI (Ps < 0.001), with no significant differences observed between C-DWI and SMS2-DWI (Ps ≥ 0.054). ADC values of rectal cancer (p = 0.943) and normal rectal wall (p = 0.360) were not significantly different among C-DWI, SMS2-DWI, and SMS3-DWI. Conclusion: SMS-DWI using an acceleration factor of 2 is feasible for rectal MRI resulting in substantial reductions in acquisition time while maintaining diagnostic image quality and similar ADC values to those of C-DWI.

• Tribology and Lubricants
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• 제36권1호
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• pp.39-46
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• 2020

Air stages are usually applied to precision engineering in sectors such as the semiconductor industry owing to their excellent performance and extremely low friction. Since the productivity of a semiconductor depends on the acceleration and deceleration performance of the air stage, many attempts have been made to improve the speed of the stage. Even during sudden start or stop sequences, the stage should maintain an air film to avoid direct contact between pad and the rail. The purpose of this study is to quantitatively predict the dynamic behavior of the air stage when acceleration and deceleration occur. The air stage is composed of two parts; the stage and the guide-way. The stage transports objects to the guideway, which is supported by an externally pressurized gas bearing. In this study, we use COMSOL Multiphysics to calculate the pressure of the air film between the stage and the guide-way and solve the two-degree-of-freedom equations of motion of the stage. Based on the specified velocity conditions such as the acceleration time and the maximum velocity of stage, we calculate the eccentricity and tilting angle of the stage. The result shows that the stiffness and damping of the gas bearing have non-linear characteristics. Hence, we should consider the operating conditions in the design process of an air stage system because the dynamic behavior of the stage becomes unstable depending on the maximum velocity and the acceleration time.

• Investigative Magnetic Resonance Imaging
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• 제10권2호
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• pp.70-80
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• 2006

목적: 본 연구의 목적은 스핀에코(spin-echo) 자기공명영상 시퀀스 (sequence)에서 혈류 (blood flow)의 영상 저하를 줄이기 위한 새로운 경사자장 널링 (Gradient moment nulling) 방법 연구에 있다. 대상 및 방법: 스핀에코 시퀀스에서 사용하는 180도 펄스 주위에 혈류 보상과 동시에 180도 펄스의 불완전에서 생기게 되는 영상 저하를 줄일 수 있는 역할을 하는 경사자장을 이용한다. 이 경사자장은 혈류의 1차 (linear flow), 2차 (acceleration flow) 및 3차 (jurk flow) 운동에 대해 항상 같은 형태를 같기 때문에 통일된 경사자장의 형태를 갖는다. 이 기술을 이용하여 1차, 2차 및 3차 혈류 움직임에 의한 보상을 할 수 있는 스핀에코 시퀀스를 만들고 그 것을 펜텀과 사람의 뇌 영상에 사용하였다. 결과: 시뮬레이션을 이용한 혈류의 움직임에 대한 보상을 확인하였고 본 연구에서 제시된 새로운 기술이 기존에 제시된 기술에 비하여 향상된 결과를 펜텀 실험과 사람의 뇌 영상에서 보여 주었다. 결론: 본 연구에서 제시된 방법을 임상에 이용하면 혈류의 움직임에 대한 보상을 최적화 할 수 있으리라고 본다.

• Geomechanics and Engineering
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• 제15권4호
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• pp.987-995
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• 2018

In this study, a relationship between small-strain shear modulus ($G_{max}$) and overconsolidation ratio (OCR) based on shear wave velocity ($V_S$) measurement was established to identify the stress history of centrifuge model ground. A centrifuge test was conducted in various centrifugal acceleration levels including loading and unloading sequences to cause various stress histories on centrifuge model ground. The $V_S$ and vertical effective stress were measured at each level of acceleration. Then, a sensitivity analysis was conducted using testing data to ensure the suitability of OCR function for the tested cohesionless soils and found that OCR can be estimated based on $V_S$ measurements irrespective of normally-consolidated or overconsolidated loading conditions. Finally, the developed $G_{max}$-OCR relationship was applied to centrifuge models constructed and tested under various induced stress-history conditions. Through a series of tests, it was concluded that the induced stress history on centrifuge model by compaction, g-level variation, and past overburden load can be analysed quantitatively, and it is convinced that the OCR evaluation technique will contribute to better interpret the centrifuge test results.

• Investigative Magnetic Resonance Imaging
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• 제21권4호
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• pp.210-222
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• 2017

Purpose: To develop a novel combination of controlled aliasing in parallel imaging results in higher acceleration (CAIPIRINHA) with integrated SSFP (CAIPI-iSSFP) for accelerated SSFP imaging without banding artifacts at 3T. Materials and Methods: CAIPI-iSSFP was developed by adding a dephasing gradient to the balanced SSFP (bSSFP) pulse sequence with a gradient area that results in $2{\pi}$ dephasing across a single pixel. Extended phase graph (EPG) simulations were performed to show the signal behaviors of iSSFP, bSSFP, and RF-spoiled gradient echo (SPGR) sequences. In vivo experiments were performed for brain and abdominal imaging at 3T with simultaneous multi-slice (SMS) acceleration factors of 2, 3 and 4 with CAIPI-iSSFP and CAIPI-bSSFP. The image quality was evaluated by measuring the relative contrast-to-noise ratio (CNR) and by qualitatively assessing banding artifact removal in the brain. Results: Banding artifacts were removed using CAIPI-iSSFP compared to CAIPI-bSSFP up to an SMS factor of 4 and 3 on brain and liver imaging, respectively. The relative CNRs between gray and white matter were on average 18% lower in CAIPI-iSSFP compared to that of CAIPI-bSSFP. Conclusion: This study demonstrated that CAIPI-iSSFP provides up to a factor of four acceleration, while minimizing the banding artifacts with up to a 20% decrease in the relative CNR.

• Molecules and Cells
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• 제43권4호
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• pp.331-339
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• 2020

Genetic modifications in noncoding regulatory regions are likely critical to human evolution. Human-accelerated noncoding elements are highly conserved noncoding regions among vertebrates but have large differences across humans, which implies human-specific regulatory potential. In this study, we found that human-accelerated noncoding elements were frequently coupled with DNase I hypersensitive sites (DHSs), together with monomethylated and trimethylated histone H3 lysine 4, which are active regulatory markers. This coupling was particularly pronounced in fetal brains relative to adult brains, non-brain fetal tissues, and embryonic stem cells. However, fetal brain DHSs were also specifically enriched in deeply conserved sequences, implying coexistence of universal maintenance and human-specific fitness in human brain development. We assessed whether this coexisting pattern was a general one by quantitatively measuring evolutionary rates of DHSs. As a result, fetal brain DHSs showed a mixed but distinct signature of regional conservation and outlier point acceleration as compared to other DHSs. This finding suggests that brain developmental sequences are selectively constrained in general, whereas specific nucleotides are under positive selection or constraint relaxation simultaneously. Hence, we hypothesize that human- or primate-specific changes to universally conserved regulatory codes of brain development may drive the accelerated, and most likely adaptive, evolution of the regulatory network of the human brain.

• Journal of Plant Biology
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• 제37권1호
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• pp.27-36
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• 1994

For establishing a transformation system of rice, an efficient introduction of foreign genes into embryogenic cell suspension by particle bombardment was conducted. The particle inflow gun based on the acceleration of DNA-coated tungsten particles using pressurized helium was constructed for delivery of DNA into rice cells. Several bombardment parameters were optimized using the transient expression of GUS gene. The conditions that gave the highest GUS gene expression of about 1000 blue spots per g fresh weight of bombarded cells include treatment of the cells with 0.5 M osmotic pressure, and use of the 410 kPa helium, 110 mm target distance, 13 mm syringe filter holder and 5 $\mu$L DNA/tungsten mixtures. It was also confirmed that rice actin promoter-intron construct gave the highest expression of all promoter-sequences studied. Eight weeks after the bombardment, stably transformed calluses were obtained on the selection medium containing 100 mg/L G418 and showed the strong activity in in situ GUS assay.

• 방송공학회논문지
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• 제17권6호
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• pp.1091-1105
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• 2012

본 논문에서는 현재 표준화가 진행 중인 HEVC (high efficiency video coding) 부호화기의 고속화, 최적화, 병렬화 연구에 앞서 통계적 특성 및 복잡도 분석을 수행하였다. HEVC는 H.264/AVC에 비해 약 2배의 압축 성능을 나타내지만 부호화기 복잡도는 크게 증가하여 이는 앞으로 해결해야할 문제로 남아있다. HEVC의 높은 부호화기 복잡도를 해결하기 위한 고속화, 최적화, 병렬화 연구에 앞서, 본 논문에서는 HEVC 참조소프트웨어인 HM 7.1을 이용하여 HEVC 부호화기의 복잡도를 측정하였다. 추가적으로, 실제 응용에서 사용될 고속 HEVC 부호화기 소프트웨어에 대한 예상 복잡도를 고속 알고리듬이 적용된 HM 7.1 소프트웨어로 측정하였다. 복잡도 측정은 공통 실험 영상 및 조건을 사용하였으며 PC 환경에서 부호화기 소프트웨어의 동작 사이클을 측정하고 이를 분석하였다. 또한, 부호화를 통해 생성된 비트스트림을 이용하여 HEVC 부호화기 소프트웨어의 부호화 구조에 따른 통계적 특성과 제한적 부호화에 따른 통계적 특성에 대하여 제시하고 이를 분석한다.

• 대한영상의학회지
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• 제85권2호
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• pp.345-362
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• 2024

자기공명영상(이하 MRI)은 복부 영상에서 국소 병변의 감지와 특성을 찾을 수 있는 것 때문에 중요한 역할을 한다. 그러나 MRI 검사에 상대적으로 긴 검사 시간과 호흡 유지 기법에서 움직임 관리와 같은 몇 가지 힘든 요인이 있다. 최근에는 검사 시간을 줄이면서 적절한 이미지 품질을 유지하는 기법인 평행 이미징, 압축 감지(compressed sensing) 및 최첨단 딥 러닝(deep learning) 기술이 등장하여 문제 해결 전략을 가능하게 하고 있다. 또한, 역동적 조영증강 영상에서 자유 호흡 기법은, 추가 차원(extra-dimensional)-부피 보간 호흡 유지 검사(volumetric interpolated breath-hold examination) 및 황금 각도 방사형 희소 병렬(golden-angle radial sparse parallel), 간 가속 볼륨 획득(liver acceleration volume acquisition) 스타와 같은, 심한 호흡곤란이나 마취 중인 환자에게서 복부 MRI를 시행하는 것을 돕는다. 이 임상화보에서는 시간을 줄이면서도 이미지 품질을 유지하기 위한 다양한 고급 복부 MRI 기술과 역동적 영상을 위한 자유 호흡 기술을 제시하고 또한 이를 통한 예시들을 보여주고자 한다. 이러한 첨단 기법들의 고찰은 적용된 시퀀스의 적절한 해석에 도움을 줄 것이다.