• Title/Summary/Keyword: accelerated conditions

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Numerical Prediction of Permanent Deformation of Automotive Weather Strip (자동차용 웨더스트립의 영구변형 예측)

  • Park, Joon-Chul;Min, Byung-Kwon;Oh, Jeong-Seok;Moon, Hyung-Il;Kim, Heon-Young
    • Transactions of the Korean Society of Automotive Engineers
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    • v.18 no.4
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    • pp.121-126
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    • 2010
  • The automotive weather strip has functions of isolating of water, dust, noise and vibration from outside. To achieve good sealing performance, weather strip should be designed to have the high contact force and wide contact area. However, these design causes excessive permanent deformation of weather strip. The causes of permanent deformation is generally explained to be the chemical material detrioration and physical variation and cyclic loading, etc. This paper introduces a numerical method to predict the permanent deformation using the time dependent viscoelastic model which is represented by Prony series in ABAQUS. Uniaxial tension and creep tests were conducted to obtain the material data. And the lab. test for the permanent deformation was accelerated during shorter time, 300 hours. The permanent deformation of weather strip was successfully predicted under the different loading conditions and different section shapes using the suggested numerical process.

Physicochemical Assessment of Quality Characteristics of Extruded Barley Under Varied Storage Conditions -II. Non-enzymatic Browning- (상이한 조건하에서 저장한 압출보리의 품질특성에 관한 이화학적 평가 -제 2 보 : 비효소적 갈색화-)

  • Shin, Hyo-Sun;Gray, J. Ian;Cuppett, Susan L.
    • Korean Journal of Food Science and Technology
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    • v.15 no.3
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    • pp.287-294
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    • 1983
  • Change of color, browning index, soluble protein, reducing sugar content, and available lysine were monitored for raw and extruded barely powders during four months of ambient and accelerated storage temperatures with $A_w$ of 0.31 and 0.71, respectively. Loss of whiteness and soluble browning pigments increased with increased $A_w$ and temperature. The raw sample had an increased rate of browning intensity than the extruded samples. Among the extruded samples, the added sucrose sample had the lowest rate of browning during storage. Loss of reducing sugar content in all samples increased with increased $A_w$ and temperature. The loss of soluble protein and of the available lysine also increased with increased $A_w$ and temperature. The loss of reducing sugar and of the available lysine was at least partly due to the Maillard browning reaction. These results have important implications in teh processing and storage of raw and extruded burleys.

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Effects of Food Grade Porcine Pancreatic Lipase on the Production of Short-Chain Fatty Acids and its Contribution (식용 돼지췌장 리파제가 저급지방산 생성과 체다치즈 풍미향상에 미치는 영향)

  • Kwak, Hae-Soo;Jeon, Ike-J.;Park, Joung-Nam
    • Korean Journal of Food Science and Technology
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    • v.22 no.3
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    • pp.248-254
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    • 1990
  • Commercial food grade porcine-pancreatic lipase was incorporated into cheese at two different levels of concentration and ripened at $7^{\circ},\;13^{\circ}\;and\;21^{\circ}C$ Gas chromatographic analysis showed that the pancreatic lipase-treated cheese produced significantly higher levels of short-chain free fatty acids than controls. At $21^{\circ}C$ the high level of pancreatic lipase-treated cheese produced medium flavor cheese at 1 wk and close to sharp flavor cheese at 3 wk without causing distinctive defects. The low level of pancreatic lipase-treated cheese developed a number of good quality cheese. They were roughly equivalent to medium and sharp cheeses when ripened at $7^{\circ},\;13^{\circ}\;and\;21^{\circ}C$ for 3 to 15wk. Statistical analyses indicated that there were significant correlations between aged Cheddar flavor and the concentration of c6 as individual short chain free fatty acids (FFA) or C4 and C6 FFA combinations. Pancreatic lipase may be applicable for the accelerated ripening of Cheddar cheese if appropriate conditions are used.

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Biopharmaceutical Evaluation of a Solid Dispersion System Containing Sibutramine Freebase

  • Lee, Min-Suk;Chang, Hee-Chul;Kim, Taewan;Park, Jung-Hwa;Lee, Bong-Sang;Kim, Sung-Hee;Kim, Do-Hwan;Kim, Bo-Gyun;Oh, Seong-Tae;Kang, Myung-Joo;Park, Jong-Hyeok;Lee, Jaehwi;Choi, Young-Wook
    • Bulletin of the Korean Chemical Society
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    • v.29 no.4
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    • pp.749-754
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    • 2008
  • To increase the solubility of sibutramine freebase, the solid dispersion was prepared using a fluid-bed granulator. The solid dispersion containing sibutramine freebase was characterized by differential scanning calorimetry (DSC) and powder X-ray diffraction (XRD). After filling the sibutramine solid dispersion in the gelatin hard capsule, we performed in vitro dissolution test, the stability test under accelerated conditions and pharmacokinetic study in beagle dogs. The DSC and XRD data showed that sibutramine solid dispersion would be amorphous state. The dissolution rate of sibutramine solid dispersion was significantly increased about 70% than sibutramine freebase. The stability of sibutramine solid dispersion capsules was equivalent or above to commercial product of sibutramine. In beagle dogs, the sibutramine solid dispersion showed equivalent pharmacokinetic behavior with commercial product of sibutramine hydrochloride. In conclusion, the solid dispersion system provided a possible way to overcome the low solubility of sibutramine freebase, and the sibutramine solid dispersion can be a bioequivalent with the commercial product in humans.

Preliminary Study of the Leaching Resistance of Boron from Borate Treated Wood by the Dual Treatment with Water-Repellent Preservative and Methyl Metacrylate (방부성(防腐性) 발수제(撥水劑)와 methyl metacrylate 이중처리(二重處理)에 의(依)한 붕소화합물(硼素化合物) 처리재(處理材)로부터 붕소(硼素)의 용탈(溶脫) 저항성(抵抗性)에 관(關)한 기초연구(基礎硏究))

  • Kim, Gyu-Hyeok;Ra, Jong-Bum
    • Journal of the Korean Wood Science and Technology
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    • v.22 no.4
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    • pp.13-18
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    • 1994
  • Sapwood samples of pitch pine were treated with disodium octaborate alone by dip-diffusion, or in combination with water-repellent preservative(WRP) and methyl metacrylate(MMA). Treated samples were subjected to an accelerated leaching test for determining the improvement of leaching resistance and to soft rot and mold tests for evaluating the increase in bioefficacy, due to the addition of WRP and MMA applied as a second treatment. The addition of WRP and MMA retarded leaching of boron to some extent from treated samples and this retardation can be explained by improved water repellency of WRP and MMA treated samples. Borate /WRP and borate /MMA systems will not qualify borate treated wood for ground and fresh water contact use but may improve performance of borate treated wood in above-ground applications not subjected to continuous wetting conditions. Bioefficacy against soft rot fungi and mold fungi was improved by a second treatment with WRP. However, improvement in the performance of borate /MMA systems was not observed. Considering improvement in both resistance of leaching and bioefficacy against micro fungi by the treatment of WRP and MMA, simultaneously, the dual treatment of borate treated wood by MMA containing co-biocides might be believed as an ideal treatment system.

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On the Design of Cantilever Type High Speed Towing Carriage with Excellent Acceleration Performance (가속성능이 우수한 외팔보형 고속예인전차의 설계)

  • Kim, Jae Sung;Kim, Hyochul
    • Journal of the Society of Naval Architects of Korea
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    • v.53 no.3
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    • pp.228-236
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    • 2016
  • Extraordinarily the establishment of towing tank has been initiated after the allocation of space at the basement floor of existing building through remodeling procedure. Therefore the asymmetric tank should be unavoidably determined by compromising with the allowable space and existing building structure. Consequently the shape of towing carriage ought to be selected as a cantilever type to match with the given environmental conditions. Finally the major role of the towing tank has been configured on the fundamental research work for the high speed marine vehicles. Due to the limited length of towing tank, it is appeared that the carriage should accelerated with 1.2m/sec2 which is equivalent to twice of the maximum acceleration in ordinary practices on design application of carriage. In such a condition the exerted total power of motor could not be converted to traction force of the carriage without slip for the acceleration. To overcome these difficulties the contact pressure of a horizontal traction wheel to rail has been reinforced by the elastic recovery force of springs on supporting rollers. It is believed that the design experience of the high speed towing carriage under unusual circumferential condition and acceleration barrier could be utilized not only on the design of high speed towing carriage but also on the improvement of existing facilities.

Study on Mechanisms and Orographic Effect for the Springtime Downslope Windstorm over the Yeongdong Region (봄철 영동 지역 국지 하강풍 메커니즘과 지형 효과에 대한 연구)

  • Kim, Jung-Hoon;Chung, Il-Ung
    • Atmosphere
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    • v.16 no.2
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    • pp.67-83
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    • 2006
  • The statistical analysis for the springtime windstorm in Korea shows that Yeongdong region has the highest occurrence frequency during recent 10 years. The objective of this study is to find possible mechanisms for the downslope windstorm formation in the Yeongdong region by using a mesoscale numerical model, WRF. Dynamical process, wave breaking (hereafter WB), is qualitatively investigated as the candidate mechanism for a windstorm event occurred in 5 April, 2005. WB is developed in upper troposphere downstream, since stable air is lifted by the Taebaek mountain. This process can cause and maintain the severe downslope windstorm by drawing the upper flow down to the surface. And the intensified downslope wind leads the hydraulic jump (hereafter HJ) in downstream region. Froude numbers at Chuncheon (upslope side), Seorak Mountain (crest), Yangyang (lee side), and the East Sea (distant downstream position) are estimated by about 0.4, 1.0, 1.6, and 0.6, respectively. This result implies that the accelerated and supercritical (Fr>1) flow adjusts to the ambient subcritical (Fr<1) conditions in the turbulent HJ. In addition, we find the formation of upstream inversion near top level of the mountain cause the intensification of HJ. Experiments to examine the orographic effect on the mechanisms suggest that the magnitudes of WB and HJ are larger in the experiment of higher topography, but there is no significant difference of windstorm magnitude among the experiments. Another important result from these sensitivity experiments is that the intensity of downslope windstorm strongly depends on the magnitude of upper (2~4 km) wind in upstream side.

Investigation of Degradation Mechanism of Rabeprazole with Solid State Pharmaceutical Excipients

  • Ren, Shan;Tran, Thao Truong-Dinh;Tran, Phuong Ha-Lien;Rhee, Yun-Seok;Lee, Beom-Jin
    • Journal of Pharmaceutical Investigation
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    • v.40 no.6
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    • pp.367-372
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    • 2010
  • Rabeprazole sodium (RPN) is known to be very unstable at acidic condition or some acidic pharmaceutical excipients such as acrylic acid polymer (carbomer 934) with carboxylic acids. Thus, degradation mechanism of binary blends of rabeprazole with pharmaceutical excipients in a solid state without using solvents at three different ratios (3:1, 1:1 and 1:3) was investigated using Fourier transform infrad (FTIR) spectroscopy. Alkalizer (MgO), neutral hydroxypropymethylcellulose (HPMC 4000) were also tested for comparison. The binary blends were stored under accelerated conditions ($40^{\circ}C$/75% relative humidity) for two weeks. The concentration of thioether rabeprazole from the binary blends with acidic carbomer 934 increased as the rabeprazole concentration decreased. In addition, the degradation half-life of rabeprazole as well as the relative peak area ratios obtained from FTIR spectra of S=O stretching at $1094.1\;cm^{-1}$ decreased consistently as the fraction of carbomer 934 increased due to its sensitivity between the basic benzimidazole nitrogen and carboxylic acid group of carbomer 934. The physical appearance also turned into strong brown color in the presence of carbomer 934. In contrast, there were no significant changes in the degradation kinetics of rabeprazole with MgO and HPMC 4000 in a solid state. This present study demonstrated that the solid-state compatibility test with the aid of HPLC chromatographic and FTIR spectral analyses could offer a valuable methodology to select suitable pharmaceutical excipients and to elucidate the degradation mechanism of RPN for drug formulations at the early formulation stages.

THE REMINERALIZING EFFECTS OF EARLY ENAMEL CAR10US LESION BY SUPERSATURATED BUFFER SOLUTION UNDER PH CYCLING MODEL (pH 순환 모델에서 과포화 용액의 초기 우식 법랑질에 대한 재광화 효과)

  • 김소라;홍석진;노병덕;이찬영;금기연
    • Restorative Dentistry and Endodontics
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    • v.26 no.4
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    • pp.341-349
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    • 2001
  • Dental caries is the most common oral disease. There are many factors contributing to its development, but complete understanding and prevention are not fully known. However, it is possible to remineralize the early enamel curious lesion by fluoride containing remineralization solution. Recently the pH-cycling model has been used to examine the effect of fluoride solution on remineralization of artificial caries in vitro as it can closely simulate the conditions encountered in vivo within a carefully controlled environment. The aim of this study was to evaluate the remineralizing effects of supersaturated buffer solutions under pH-cycling model. The specimen with 3mm-diameter was made using mature bovine incisors which has no caries and has sound enamel surface. Early curious lesions were produced by suspending each specimens into demineralization solution at pH 5.0 for 33 hours and the specimen whose surface hardness value ranged from 25 to 45 VHN were used. The pH cycling treatment regimen consisted of 5 min soaks of three treatment solutions four times per days for 15 days and the continuous cycling of demineralization and remineralization were carried out for 15 days. Following the pH-cycling treatment regimen, the specimens' surface microhardness were measured by the Vickers hardness test (VHN) and analyzed by ANOVA and Duncan's multiple-range test. 1. The surface microhardness value of supersaturated solution, Senstime, and Gagline groups were increased after pH cycling, and that of supersaturated solution was significantly Increased compared to saline group(P<0.05). 2. The surface remineralization effect of fluoride containing solutions was accelerated by saliva under pH-cycling mode 3. The pH cycling model was considered appropriate to mimic the intra-oral pH changes when evaluating demineralization and remineralization in vitro. Under the results of above study, salivary remineralization effect can be improved by fluoride containing remineralization solution. The pH-cycling model was considered appropriate to mimic the intra-oral pH changes when evaluating demineralization and remineralization in vitro.

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A Boundary-Scan Based On-Line Circuit Performance Monitoring Scheme (경계 스캔 기반 온-라인 회로 성능 모니터링 기법)

  • Park, Jeongseok;Kang, Taegeun;Yi, Hyunbean
    • Journal of the Institute of Electronics and Information Engineers
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    • v.53 no.1
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    • pp.51-58
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    • 2016
  • As semiconductor technology has developed, device performance has been improved. However, since device structures became smaller, circuit aging due to operational and environmental conditions can be accelerated. Circuit aging causes a performance degradation and eventually a system error. In reliable systems, a failure due to aging might cause a great disaster. Therefore, these systems need a performance degradation prediction function so that they can take action in advance before a failure occurs. This paper presents an on-line circuit performance degradation monitoring scheme for predicting a failure by detecting performance degradation during circuit normal operation. In our proposed scheme, IEEE 1149.1 output boundary scan cells and TAP controller are reused. The experimental result shows that the proposed architecture can monitor the performance degradation during normal operation without stopping the circuit.